J. Schupp

发表

A Pathway for the Control of Anoikis Sensitivity by E-Cadherin and Epithelial-to-Mesenchymal Transition

Fan Zhang, Sun Hee Park, David L. Rimm, 2011, Molecular and Cellular Biology.

Heterogeneity of O6-alkylguanine-DNA-alkyltransferase measured by flow cytometric analysis in blood and bone marrow mononuclear cells.

S. Gerson, O. Koç, K. Lee, 1998, Clinical cancer research : an official journal of the American Association for Cancer Research.

Acetylation of Aβ40 alters aggregation in the presence and absence of lipid membranes.

S. Valentine, J. Schupp, David M. Smith, 2019, ACS chemical neuroscience.

BRCA1 activates a G2-M cell cycle checkpoint following 6-thioguanine-induced DNA mismatch damage.

T. Kinsella, K. Yamane, J. Schupp, 2007, Cancer research.

Methoxyamine potentiates iododeoxyuridine-induced radiosensitization by altering cell cycle kinetics and enhancing senescence

T. Kinsella, Xuehuo Zeng, T. Yan, 2006, Molecular Cancer Therapeutics.

Ionizing Radiation and G2 Arrest Responses without Altering Survival after Loss of DNA Mismatch Repair Imparts Defective cdc2 Signaling

H. Hwang, T. Yan, J. Schupp, 2013 .

Schedule-dependent drug effects of oral 5-iodo-2-pyrimidinone-2'-deoxyribose as an in vivo radiosensitizer in U251 human glioblastoma xenografts.

T. Kinsella, T. Yan, T. Radivoyevitch, 2005, Clinical cancer research : an official journal of the American Association for Cancer Research.

Schedule-Dependent Drug Effects of Oral 5-Iodo-2-Pyrimidinone-2′-Deoxyribose as an In vivo Radiosensitizer in U251 Human Glioblastoma Xenografts

T. Kinsella, T. Yan, T. Radivoyevitch, 2005, Clinical Cancer Research.

Preclinical study of the systemic toxicity and pharmacokinetics of 5-iodo-2-deoxypyrimidinone-2'-deoxyribose as a radiosensitizing prodrug in two, non-rodent animal species: implications for phase I study design.

H. Hwang, T. Davis, T. Kinsella, 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

Quantitative Analysis of the Effects of Iododeoxyuridine and Ionizing Radiation Treatment on the Cell Cycle Dynamics of DNA Mismatch Repair Deficient Human Colorectal Cancer Cells

K. Loparo, T. Kinsella, Evren Gurkan-Cavusoglu, 2014 .

Quantitative analysis of the effects of iododeoxyuridine and ionising radiation treatment on the cell cycle dynamics of DNA mismatch repair deficient human colorectal cancer cells.

K. Loparo, T. Kinsella, Evren Gurkan-Cavusoglu, 2013, IET systems biology.

Selection for G156A O6-methylguanine DNA methyltransferase gene-transduced hematopoietic progenitors and protection from lethality in mice treated with O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea.

S. Gerson, O. Koç, K. Lee, 1997, Cancer research.

Leukocyte O6-alkylguanine-DNA alkyltransferase from human donors is uniformly sensitive to O6-benzylguanine.

S. Gerson, J. Schupp, L. Liu, 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

Leukocyte O 6-Alkylguanine-DNA Alkyltransferase from Human Donors Is Uniformly Sensitive to O 6-Benzylguanine 1

Lili Liu, A. Pegg, S. Gerson, 1999 .

The interaction between two radiosensitizers: 5-iododeoxyuridine and caffeine.

Tomas Radivoyevitch, Yuji Seo, Tao Yan, 2006, Cancer research.

Differential Radiosensitization in DNA Mismatch Repair-Proficient and -Deficient Human Colon Cancer Xenografts with 5-Iodo-2-pyrimidinone-2′-deoxyribose

Yuji Seo, Tao Yan, T. Kinsella, 2004, Clinical Cancer Research.

Preclinical toxicity and efficacy study of a 14-day schedule of oral 5-iodo-2-pyrimidinone-2'-deoxyribose as a prodrug for 5-iodo-2'-deoxyuridine radiosensitization in U251 human glioblastoma xenografts.

K. Kunugi, T. Davis, T. Kinsella, 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

Differential degradation rates of inactivated alkyltransferase in blood mononuclear cells and tumors of patients after treatment with O(6)-benzylguanine.

J. Haaga, J. Willson, S. Gerson, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

Selective radiosensitization of drug-resistant MutS homologue-2 (MSH2) mismatch repair-deficient cells by halogenated thymidine (dThd) analogues: Msh2 mediates dThd analogue DNA levels and the differential cytotoxicity and cell cycle effects of the dThd analogues and 6-thioguanine.

N. de Wind, H. Hwang, T. Davis, 2000, Cancer research.

Loss of DNA mismatch repair imparts defective cdc2 signaling and G(2) arrest responses without altering survival after ionizing radiation.

M. Veigl, D. Boothman, H. Hwang, 2001, Cancer research.

Inhibition of base excision repair potentiates iododeoxyuridine-induced cytotoxicity and radiosensitization.

H. Hwang, T. Kinsella, T. Radivoyevitch, 2003, Cancer research.

The DNA N-glycosylase MED1 exhibits preference for halogenated pyrimidines and is involved in the cytotoxicity of 5-iododeoxyuridine.

T. Kinsella, A. Bellacosa, Salvatore Cortellino, 2006, Cancer research.

Modulation of the activity of methyl binding domain protein 4 (MBD4/MED1) while processing iododeoxyuridine generated DNA mispairs

T. Kinsella, M. Aziz, J. Schupp, 2009, Cancer biology & therapy.

A conceptual modeling framework for the study of DNA mismatch repair pathway to improve therapeutic gain in cancer treatment

K. Loparo, T. Kinsella, J. Schupp, 2007, 2007 IEEE/NIH Life Science Systems and Applications Workshop.

ATP binding to neighbouring subunits and intersubunit allosteric coupling underlie proteasomal ATPase function

J. Schupp, David M. Smith, Aaron Snoberger, 2015, Nature Communications.

Probabilistic modeling of DNA mismatch repair effects on cell cycle dynamics and iododeoxyuridine-DNA incorporation.

Kenneth A Loparo, K. Loparo, T. Kinsella, 2007, Cancer research.

DNA Mismatch Repair Initiates 6-Thioguanine–Induced Autophagy through p53 Activation in Human Tumor Cells

T. Kinsella, Xuehuo Zeng, T. Yan, 2007, Clinical Cancer Research.

A Pathway for the Control of Anoikis Sensitivity by E-Cadherin and Epithelial-to-Mesenchymal Transition

B. Cieply, D. Rimm, Fan Zhang, 2011, Molecular and Cellular Biology.

Analysis of cell cycle dynamics using probabilistic cell cycle models

Kenneth A. Loparo, Evren Gurkan-Cavusoglu, Jane E. Schupp, 2011, 2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.