M. Webb

发表

Probing the domain structure of the type IC DNA methyltransferase M.EcoR124I by limited proteolysis.

I. Taylor, K. Firman, G. Kneale, 1995, Journal of molecular biology.

Surface labelling of the type I methyltransferase M.EcoR124I reveals lysine residues critical for DNA binding.

I. Taylor, G. Kneale, M. Webb, 1996, Journal of molecular biology.

Deletions within the DNA recognition subunit of M.EcoR124I that identify a region involved in protein-protein interactions between HsdS and HsdM.

K. Firman, J. Patel, V. Zinkevich, 1994, Journal of molecular biology.

Developing functional assays for BRCA1 unclassified variants.

M. Webb, 2010, Methods in molecular biology.

Cancer Susceptibility

M. Webb, 2010, Methods in Molecular Biology.

The eukaryotic elongation factor eEF1A1 interacts with SAMHD1.

I. Taylor, Y. Crow, D. Schwefel, 2015, The Biochemical journal.

Highly branched stimuli responsive poly[(N-isopropyl acrylamide)-co-(1,2-propandiol-3-methacrylate)]s with protein binding functionality.

S. Rimmer, S. Carter, M. Webb, 2005, Macromolecular bioscience.

HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase

Geoff Kelly, Michelle Webb, Jonathan P. Stoye, 2011, Nature.

A guide for functional analysis of BRCA1 variants of uncertain significance

Etienne Rouleau, Aneliya Velkova, Alvaro Galli, 2012, Human mutation.

Structural requirements for cooperative binding of HMG1 to DNA minicircles.

A. Travers, D. Payet, M. Webb, 2001, Journal of molecular biology.

Phospho-dependent Regulation of SAMHD1 Oligomerisation Couples Catalysis and Restriction

I. Taylor, S. Howell, H. Groom, 2015, PLoS pathogens.

Identification and purification of a soluble region in the breast cancer susceptibility protein BRCA2.

M. Webb, D. Finch, 2005, Protein expression and purification.

The pH-dependence of the Escherichia coli RNase HII-catalysed reaction suggests that an active site carboxylate group participates directly in catalysis.

J. Grasby, M. Webb, James A Bastock, 2007, Journal of molecular biology.

GTF2IRD1 regulates transcription by binding an evolutionarily conserved DNA motif ‘GUCE’

M. Tassabehji, A. Sharrocks, T. Jowitt, 2007, FEBS letters.

A kinetic analysis of the nucleotide-induced allosteric transitions of GroEL.

A. Clarke, S. Burston, N. Hay, 1999, Journal of molecular biology.

Structure-specific binding of the two tandem HMG boxes of HMG1 to four-way junction DNA is mediated by the A domain.

M. Webb, J. Thomas, Jean O. Thomas, 1999, Journal of molecular biology.

Chemical modification of lysine by reductive methylation. A probe for residues involved in DNA binding.

I. Taylor, M. Webb, 2001, Methods in molecular biology.

A critical role in structure-specific DNA binding for the acetylatable lysine residues in HMGB1.

Matthew A. Watson, K. Stott, R. Assenberg, 2008, The Biochemical journal.

Proteomic analysis of Escherichia coli biofilms reveals the overexpression of the outer membrane protein OmpA

C. Douglas, S. Rimmer, M. Webb, 2006, Proteomics.

Analysis of the DNA Binding Activity of BRCA1 and Its Modulation by the Tumour Suppressor p53

R. Naseem, M. Webb, 2008, PloS one.

Mapping and conformational characterization of the DNA-binding region of the breast cancer susceptibility protein BRCA1.

T. Jowitt, R. Naseem, M. Webb, 2006, The Biochemical journal.

Purification and characterisation of a soluble N-terminal fragment of the breast cancer susceptibility protein BRCA1.

Michelle Webb, Riffat Naseem, R. Naseem, 2004, Journal of molecular biology.

Purification and characterisation of the breast cancer metastasis suppressor, BRMS1.

R. Naseem, M. Webb, J. Smith, 2009, Protein expression and purification.

A guide for functional analysis of BRCA1 variants of uncertain significance

F. Couch, R. Brandão, M. Blok, 2012, Human mutation.