F. Tanious

发表

DNA sequence dependent monomer-dimer binding modulation of asymmetric benzimidazole derivatives.

Donald Hamelberg, Christian Bailly, C. Bailly, 2004, Journal of the American Chemical Society.

Synthesis and structure-DNA binding relationship analysis of DNA triple-helix specific intercalators.

L. Strekowski,, W. Wilson, A. Kiselyov, 1996, Journal of medicinal chemistry.

Bis-4-aminoquinolines: novel triple-helix DNA intercalators and antagonists of immunostimulatory CpG-oligodeoxynucleotides.

L. Strekowski,, W. Wilson, L. Manzel, 2003, Bioorganic & Medicinal Chemistry.

New triple-helix DNA stabilizing agents.

L. Strekowski,, W. Wilson, T. Górecki, 2005, Bioorganic & medicinal chemistry letters.

Interaction of unfused tricyclic aromatic cations with DNA: a new class of intercalators.

L. Strekowski,, W. Wilson, F. Tanious, 1989, Biochemistry.

The interaction with DNA of unfused aromatic systems containing terminal piperazino substituents. Intercalation and groove-binding.

S B Kong, W D Wilson, L. Strekowski,, 1990, Biophysical chemistry.

Sequence-dependent binding of bis-amidine carbazole dications to DNA.

C. Bailly, P. Colson, W. Wilson, 2001, European journal of biochemistry.

Molecular basis for bleomycin amplification: conformational and stereoelectronic effects in unfused amplifiers.

L. Strekowski,, W. Wilson, F. Tanious, 1988, Journal of medicinal chemistry.

Binding of 4',6-diamidino-2-phenylindole (DAPI) to GC and mixed sequences in DNA: intercalation of a classical groove-binding molecule

L. Strekowski,, W. Wilson, D. Boykin, 1989 .

Kinetic and equilibrium analysis of a threading intercalation mode: DNA sequence and ion effects.

W. Wilson, F. Tanious, S. Yen, 1991, Biochemistry.

DAPI (4',6-diamidino-2-phenylindole) binds differently to DNA and RNA: minor-groove binding at AT sites and intercalation at AU sites.

J. Veal, W. Wilson, F. Tanious, 1992, Biochemistry.

Diguanidino and "reversed" diamidino 2,5-diarylfurans as antimicrobial agents.

J. Perfect, W. Wilson, D. Boykin, 2001, Journal of medicinal chemistry.

Kinetic Analysis of Drug-Nucleic Acid Binding Modes: Absolute Rates and Effects of Salt Concentration

W. Wilson, F. Tanious, 1994 .

Substituent position dictates the intercalative DNA-binding mode for anthracene-9,10-dione antitumor drugs.

S. Neidle, W. Wilson, T. C. Jenkins, 1992, Biochemistry.

Distribution of furamidine analogues in tumor cells: targeting of the nucleus or mitochondria depending on the amidine substitution.

C. Bailly, W. Wilson, Arvind Kumar, 2002, Cancer research.

Trisubstituted acridine derivatives as potent and selective telomerase inhibitors.

James M. Morrell, G. Chessari, S. Neidle, 2003, Journal of medicinal chemistry.

Synthesis and antiprotozoal activity of aza-analogues of furamidine.

W. Wilson, D. Boykin, R. Brun, 2003, Journal of medicinal chemistry.

Strand Invasion of DNA Quadruplexes by PNA: Comparison of Homologous and Complementary Hybridization

D. Ly, W. Wilson, B. Armitage, 2013, Chembiochem : a European journal of chemical biology.

Effect of base-pair sequence on the conformations and thermally induced transitions in oligodeoxyribonucleotides containing only AT base pairs.

G. Zon, W. Wilson, R. Wartell, 1990, Biochemistry.

Dicationic biphenyl benzimidazole derivatives as antiprotozoal agents.

W. Wilson, D. Boykin, R. Brun, 2004, Bioorganic & medicinal chemistry.

Synthesis, DNA affinity, and antiprotozoal activity of fused ring dicationic compounds and their prodrugs.

W. Wilson, D. Boykin, R. Brun, 2005, Journal of medicinal chemistry.

Anti-Pneumocystis carinii pneumonia activity of dicationic carbazoles

W. Wilson, D. Boykin, J. Hall, 1997 .

DNA sequence dependent binding modes of 4',6-diamidino-2-phenylindole (DAPI).

R. L. Jones, L. Strekowski,, W. Wilson, 1990, Biochemistry.

Synthesis and DNA interactions of benzimidazole dications which have activity against opportunistic infections.

W. Wilson, R. Tidwell, F. Tanious, 1996, Journal of medicinal chemistry.

New triple-helix DNA stabilizing agents.

L. Strekowski,, W. Wilson, T. Górecki, 2005, Bioorganic & medicinal chemistry letters.

DNA triple-helix specific intercalators as antigene enhancers: unfused aromatic cations.

L. Strekowski,, G. Zon, W. Wilson, 1993, Biochemistry.

DNA binding affinity of bisguanidine and bis(2-aminoimidazoline) derivatives with in vivo antitrypanosomal activity.

M. Barrett, C. Dardonville, W. Wilson, 2006, Journal of medicinal chemistry.

Distribution of furamidine analogues in tumor cells: influence of the number of positive charges.

C. Bailly, W. Wilson, Arvind Kumar, 2002, Journal of medicinal chemistry.

Molecular determinants for DNA minor groove recognition: design of a bis-guanidinium derivative of ethidium that is highly selective for AT-rich DNA sequences.

Christian Bailly, C. Bailly, P. Colson, 2005, Biochemistry.

The interaction of unfused polyaromatic heterocycles with DNA: intercalation, groove-binding and bleomycin amplification.

R. L. Jones, L. Strekowski,, W. Wilson, 1990, Anti-cancer drug design.

Nucleic Acid Interactions of Unfused Aromatic Cations: Evaluation of Proposed Minor-Groove, Major-Groove, and Intercalation Binding Modes

Christian Bailly, W. David Wilson, C. Bailly, 1998 .

Synthesis and structure-DNA binding relationship analysis of DNA triple-helix specific intercalators.

L. Strekowski,, S. Lin, W. Wilson, 1996, Journal of medicinal chemistry.

Antiparasitic compounds that target DNA.

W. Wilson, D. Boykin, J. Hall, 2008, Biochimie.

Effects of compound structure on carbazole dication-DNA complexes: tests of the minor-groove complex models.

W D Wilson, C. Bailly, W. Wilson, 2000, Biochemistry.

Trisubstituted acridines as G-quadruplex telomere targeting agents. Effects of extensions of the 3,6- and 9-side chains on quadruplex binding, telomerase activity, and cell proliferation.

Stephen Neidle, Javier Cuesta, Mekala Gunaratnam, 2006, Journal of medicinal chemistry.

2,4-Diphenyl furan diamidines as novel anti-Pneumocystis carinii pneumonia agents.

W. Wilson, D. Boykin, J. Hall, 1999, Journal of medicinal chemistry.

Synthesis and antiprotozoal activity of novel bis-benzamidino imidazo[1,2-a]pyridines and 5,6,7,8-tetrahydro-imidazo[1,2-a]pyridines.

W. Wilson, D. Boykin, R. Brun, 2008, Bioorganic & medicinal chemistry.

Novel Dications with Unfused Aromatic Systems: Trithiophene and Trifuran Derivatives of Furimidazoline

C. Bailly, P. Colson, W. Wilson, 2001, Chembiochem : a European journal of chemical biology.

The activity of diguanidino and 'reversed' diamidino 2,5-diarylfurans versus Trypanosoma cruzi and Leishmania donovani.

W. Wilson, D. Boykin, R. Brun, 2003, Bioorganic & medicinal chemistry letters.

Synthesis and antiparasitic evaluation of bis-2,5-[4-guanidinophenyl]thiophenes.

W. Wilson, D. Boykin, R. Brun, 2007, European journal of medicinal chemistry.

Synthesis and anti-Pneumocystis carinii pneumonia activity of novel dicationic dibenzothiophenes and orally active prodrugs.

W. Wilson, J. Hall, R. Tidwell, 1999, European journal of medicinal chemistry.

Dicationic dibenzofuran derivatives as anti-Pneumocystis carinii pneumonia agents: synthesis, DNA binding affinity, and anti-P. carinii activity in an immunosuppressed rat model

W. Wilson, J. Hall, R. Tidwell, 1999 .

Anti-Pneumocystis carinii Pneumonia Activity of Dicationic Carbazoles.

W. Wilson, D. Boykin, J. Hall, 1998 .

Structure-based design of selective and potent G quadruplex-mediated telomerase inhibitors

Stephen Neidle, W. David Wilson, S. Neidle, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Structure-specific recognition of quadruplex DNA by organic cations: influence of shape, substituents and charge.

S. Neidle, W. Wilson, D. Boykin, 2007, Biophysical chemistry.

A new type of DNA minor-groove complex: carbazole dication-DNA interactions.

W. Wilson, R. Tidwell, F. Tanious, 1997, Biochemistry.

Targeting DNA with novel diphenylcarbazoles.

Christian Bailly, C. Bailly, P. Colson, 2004, Biochemistry.

Binding of unfused aromatic cations to DNA. The influence of molecular twist on intercalation

L. Strekowski,, S. Neidle, W. Wilson, 1988 .

New approach to conformational analysis of heterobiaryls in solution

L. Strekowski,, W. Wilson, S. Chandrasekaran, 1986 .

Amplification of bleomycin-mediated degradation of DNA.

L. Strekowski,, W. Wilson, F. Tanious, 1987, Journal of medicinal chemistry.

Quantitative structure-activity relationship analysis of cation-substituted polyaromatic compounds as potentiators (amplifiers) of bleomycin-mediated degradation of DNA.

L. Strekowski,, W. Wilson, S. Crow, 1991, Journal of medicinal chemistry.

Unusually strong binding to the DNA minor groove by a highly twisted benzimidazole diphenylether: induced fit and bound water.

P. Peixoto, C. Bailly, M. Georgiadis, 2007, Biochemistry.

Dications that target the DNA minor groove: compound design and preparation, DNA interactions, cellular distribution and biological activity.

W. Wilson, Binh Nguyen, D. Boykin, 2005, Current medicinal chemistry. Anti-cancer agents.

Novel dicationic imidazo[1,2-a]pyridines and 5,6,7,8-tetrahydro-imidazo[1,2-a]pyridines as antiprotozoal agents.

W. Wilson, D. Boykin, R. Brun, 2004, Journal of medicinal chemistry.

A thermodynamic and structural analysis of DNA minor-groove complex formation.

S Neidle, W D Wilson, S. Neidle, 2000, Journal of molecular biology.

Different binding mode in AT and GC sequences for unfused-aromatic dications.

W. Wilson, A. Kumar, F. Tanious, 1994, Journal of biomolecular structure & dynamics.

A high-throughput, high-resolution strategy for the study of site-selective DNA binding agents: analysis of a "highly twisted" benzimidazole-diamidine.

M. Georgiadis, W. Wilson, E. Long, 2006, Journal of the American Chemical Society.

Biosensor-surface plasmon resonance: quantitative analysis of small molecule-nucleic acid interactions.

Binh Nguyen, W. Wilson, Binh Nguyen, 2007, Methods.

Diphenyl Furans and Aza Analogs: Effects of Structural Modification on In Vitro Activity, DNA Binding, and Accumulation and Distribution in Trypanosomes

W. Wilson, Arvind Kumar, D. Boykin, 2007, Antimicrobial Agents and Chemotherapy.

A crystallographic and spectroscopic study of the complex between d(CGCGAATTCGCG)2 and 2,5-bis(4-guanylphenyl)furan, an analogue of berenil. Structural origins of enhanced DNA-binding affinity.

S Neidle, W D Wilson, S. Neidle, 1995, Biochemistry.

Carboranyl Oligonucleotides. 2. Synthesis and Physicochemical Properties of Dodecathymidylate Containing 5-(o-Carboran-1-yl)-2'-deoxyuridine

R. Schinazi, W. Wilson, F. Tanious, 1994 .

Kinetic Discrimination in Recognition of Dna Quadruplex Targets by Guanine-rich Heteroquadruplex-forming Pna Probes. Kinetic Discrimination in Recognition of Dna Quadruplex Targets by Guanine-rich Heteroquadruplex-forming Pna Probes Nih Public Access Supplementary Material Refer to Web Version on Pu

D. Ly, W. Wilson, B. Armitage, 2022 .

Loop and backbone modifications of peptide nucleic acid improve g-quadruplex binding selectivity.

D. Ly, W. Wilson, B. Armitage, 2009, Journal of the American Chemical Society.

High-affinity homologous peptide nucleic acid probes for targeting a quadruplex-forming sequence from a MYC promoter element.

D. Ly, W. Wilson, B. Armitage, 2007, Biochemistry.

Antitumor polycyclic acridines. 20. Search for DNA quadruplex binding selectivity in a series of 8,13-dimethylquino[4,3,2-kl]acridinium salts: telomere-targeted agents.

W. Wilson, J. Mergny, C. Laughton, 2008, Journal of medicinal chemistry.

Evaluation of drug-nucleic acid interactions by thermal melting curves.

W. Wilson, C. T. Rigl, F. Tanious, 1997, Methods in molecular biology.

Biosensor-surface plasmon resonance methods for quantitative analysis of biomolecular interactions.

Binh Nguyen, W. Wilson, Binh Nguyen, 2008, Methods in cell biology.

The Effects of Ligand Structure on Binding Mode and Specificity in the Interaction of Unfused Aromatic Cations with DNA

W. Wilson, D. Boykin, B. Das, 1990 .

Cooperative dimerization of a heterocyclic diamidine determines sequence-specific DNA recognition.

Lei Wang, Christian Bailly, C. Bailly, 2003, Biochemistry.

Diguanidino and “Reversed” Diamidino 2,5‐Diarylfurans as Antimicrobial Agents.

J. Perfect, W. Wilson, D. Boykin, 2001 .

Kinetic discrimination in recognition of DNA quadruplex targets by guanine-rich heteroquadruplex-forming PNA probes.

F. Tanious, Danith H. Ly, Connor T. Murphy, 2011, Chemical communications.

Antiparasitic compounds that target DNA.

D. Boykin, F. Tanious, D. Tevis, 2008, Biochimie.