Fuchun Xie

发表

YHHU0895, a novel synthetic small-molecule microtubule-destabilizing agent, effectively overcomes P-glycoprotein-mediated tumor multidrug resistance.

L. Lou, H. Quan, Cheng-ying Xie, 2012, Cancer letters.

Synthesis and biological evaluation of 2,4,5-substituted pyrimidines as a new class of tubulin polymerization inhibitors.

Xiao-Ping Shi, L. Lou, H. Quan, 2011, Journal of medicinal chemistry.

Synthesis and biological evaluation of novel 2,4,5-substituted pyrimidine derivatives for anticancer activity.

L. Lou, Lizhi Zhao, Youhong Hu, 2009, Bioorganic & medicinal chemistry letters.

Bidirectional Control of Coronary Vascular Resistance by Eicosanoids via a Novel GPCR

Jonathan W. Nelson, S. Kaul, M. Grafe, 2018, bioRxiv.

Synthesis of 14,15-EET from Arachidonic Acid Using Urea–Hydrogen Peroxide as the Oxidant

N. Alkayed, Bingbing X. Li, Xiangshu Xiao, 2015 .

Identification, synthesis and evaluation of substituted benzofurazans as inhibitors of CREB-mediated gene transcription.

Bingbing X. Li, Xiangshu Xiao, Fuchun Xie, 2013, Bioorganic & medicinal chemistry letters.

Systemic Inhibition of CREB is Well-tolerated in vivo

D. Qian, S. Kazmierczak, B. Habecker, 2016, Scientific Reports.

Domino reaction to functionalized 2-hydroxybenzophenones from electron-deficient chromones and 1,3-dicarbonyl compounds.

J. Gong, Hong Chen, Youhong Hu, 2011, The Journal of organic chemistry.

Three-component, one-pot synthesis of 2,4,5-substituted pyrimidines library for screening against human hepatocellular carcinoma BEL-7402 cells.

L. Lou, Shukun Li, Youhong Hu, 2007, Journal of combinatorial chemistry.

Synthesis of novel functional polycyclic chromones through Michael addition and double cyclizations.

Youhong Hu, Fuchun Xie, Xuxing Chen, 2011, Organic & biomolecular chemistry.

Base-promoted one-pot tandem reaction of 3-(1-alkynyl)chromones under microwave irradiation to functionalized amino-substituted xanthones.

Youhong Hu, Fuchun Xie, Yang Liu, 2010, The Journal of organic chemistry.

An efficient approach to functionalized benzo[a]xanthones through reactions of 2-methyl-3-(1-alkynyl)chromones with electron-deficient chromone-fused dienes.

J. Gong, Hong Chen, Youhong Hu, 2010, Organic letters.

Efficient construction of a 3C-xanthone-linked 3C-chromone scaffold by novel double Michael additions and cyclizations.

Hong Chen, Youhong Hu, Fuchun Xie, 2010, Organic letters.

A base-promoted tandem reaction of 3-(1-alkynyl)chromones with 1,3-dicarbonyl compounds: an efficient approach to functional xanthones.

Lizhi Zhao, Youhong Hu, Fuchun Xie, 2009, Angewandte Chemie.

Three-component, one-pot reaction for the combinatorial synthesis of 1,3,4-substituted pyrazoles.

Youhong Hu, Fuchun Xie, Gang Cheng, 2006, Journal of combinatorial chemistry.

Three‐Component, One‐Pot Reaction for the Combinatorial Synthesis of 1,3,4‐Substituted Pyrazoles.

Youhong Hu, Fuchun Xie, Gang Cheng, 2006 .

An organic molecule modulated chemoselective cyclization of alkynyl nitriles tethered to 2-alkyl substituted chromones with multireactive sites.

Youhong Hu, Fuchun Xie, Yang Liu, 2012, Organic letters.

Domino reactions of 2-methyl chromones containing an electron withdrawing group with chromone-fused dienes.

J. Gong, Hong Chen, Youhong Hu, 2012, Organic & biomolecular chemistry.

Design, synthesis, and biological evaluation of conformationally constrained analogues of naphthol AS-E as inhibitors of CREB-mediated gene transcription.

Min Jiang, Bingbing X. Li, Xiangshu Xiao, 2012, Journal of medicinal chemistry.

Synthesis and Evaluation of an O-Aminated Naphthol AS-E as a Prodrug of CREB-mediated Gene Transcription Inhibition.

Bingbing X. Li, Xiangshu Xiao, Fuchun Xie, 2013, Letters in organic chemistry.

A base-promoted desalicyloylative dimerization of 3-(1-alkynyl)chromones: an unusual approach to 2-alkynyl xanthones.

Youhong Hu, Xuan Pan, Fuchun Xie, 2010, Organic & biomolecular chemistry.

Identification of a Potent Inhibitor of CREB-Mediated Gene Transcription with Efficacious in Vivo Anticancer Activity

D. Qian, R. Sears, Bingbing X. Li, 2015, Journal of medicinal chemistry.

The ITIM-containing receptor LAIR1 is essential for acute myeloid leukemia development

Zhigang Lu, Cheng Cheng Zhang, Xin Han, 2015, Nature Cell Biology.

Novel Type of Prodrug Activation through a Long-Range O,N-Acyl Transfer: A Case of Water-Soluble CREB Inhibitor.

K. Barnhart, A. Rheingold, C. Moore, 2014, ACS medicinal chemistry letters.

Functional screening for G protein-coupled receptor targets of 14,15-epoxyeicosatrienoic acid.

Jonathan W. Nelson, S. Kaul, N. Alkayed, 2017, Prostaglandins & other lipid mediators.

Mechanistic Insights into the Activation of Ester Prodrugs of 666-15.

Bingbing X. Li, Xiangshu Xiao, Fuchun Xie, 2020, Bioorganic & medicinal chemistry letters.

Discovery of a Synergistic Inhibitor of cAMP-Response Element Binding Protein (CREB)-mediated Gene Transcription with 666-15.

Bingbing X. Li, Xiangshu Xiao, Fuchun Xie, 2019, Journal of medicinal chemistry.

Design, synthesis and biological evaluation of regioisomers of 666-15 as inhibitors of CREB-mediated gene transcription.

Bingbing X. Li, Xiangshu Xiao, Fuchun Xie, 2017, Bioorganic & medicinal chemistry letters.