Yupeng Li

发表

Design, synthesis, and biological evaluation of 3-(1H-1,2,3-triazol-1-yl)benzamide derivatives as Potent Pan Bcr-Abl inhibitors including the threonine(315)→isoleucine(315) mutant.

Xiaoyun Lu, Zheng-chao Tu, Fengxiang Zhang, 2012, Journal of medicinal chemistry.

Hyaluronic Acid Conjugates of TLR7/8 Agonists for Targeted Delivery to Secondary Lymphoid Tissue.

B. Lambrecht, Nikunj M. Shukla, B. D. De Geest, 2018, Bioconjugate chemistry.

Resolution and quantitation of mercapturic acids derived from crotonaldehyde, methacrolein, and methyl vinyl ketone in the urine of smokers and non-smokers.

S. Hecht, S. Carmella, Yupeng Li, 2020, Chemical research in toxicology.

Design, Synthesis, and Biological Evaluation of Novel EGFR PROTACs Targeting Del19/T790M/C797S Mutation.

Jian Li, Yupeng Li, Tianfeng Xu, 2022, ACS medicinal chemistry letters.

Discovery of the First-in-Class Agonist-Based SOS1 PROTACs Effective in Human Cancer Cells Harboring Various KRAS Mutations.

Hualiang Jiang, Yupeng Li, Guizhen Zhou, 2022, Journal of medicinal chemistry.

Potent anti-viral vaccine adjuvant based on pH-degradable nanogels with covalently linked small molecule imidazoquinoline TLR7/8 agonist.

B. Lambrecht, B. Schepens, X. Saelens, 2018, Biomaterials.

Mass Spectrometric Quantitation of N'-Nitrosonornicotine-1N-oxide in the Urine of Cigarette Smokers and Smokeless Tobacco Users.

S. Hecht, Yupeng Li, 2022, Chemical research in toxicology.

Investigation of 2'-Deoxyadenosine-Derived Adducts Specifically Formed in Rat Liver and Lung DNA by N'-Nitrosonornicotine Metabolism.

S. Hecht, E. Carlson, Yupeng Li, 2021, Chemical research in toxicology.

Mass Spectrometric Quantitation of Pyridyloxobutyl DNA Phosphate Adducts in Rats Chronically Treated with N'-Nitrosonornicotine.

S. Hecht, S. Balbo, Yupeng Li, 2019, Chemical research in toxicology.

Identification of an N'-Nitrosonornicotine-Specific Deoxyadenosine Adduct in Rat Liver and Lung DNA.

S. Hecht, Yupeng Li, 2021, Chemical research in toxicology.

Coumarin-benzimidazole hybrids: A review of developments in medicinal chemistry.

Yupeng Li, Ramesh Gondru, Janardhan Banothu, 2021, European journal of medicinal chemistry.

Recent Developments in the Synthesis of Indole‐Pyrazole Hybrids

Yupeng Li, K. Fabitha, C. Arya, 2022, ChemistrySelect.

Identification of GZD824 as an orally bioavailable inhibitor that targets phosphorylated and nonphosphorylated breakpoint cluster region-Abelson (Bcr-Abl) kinase and overcomes clinically acquired mutation-induced resistance against imatinib.

Xiaoyun Lu, Zheng-chao Tu, Deping Wang, 2013, Journal of medicinal chemistry.

Design, Synthesis, and Bioevaluation of Pyrido[2,3-d]pyrimidin-7-ones as Potent SOS1 Inhibitors.

Kaixian Chen, Meiying Liu, Yupeng Li, 2023, ACS medicinal chemistry letters.

Design and Optimization of 3'-(Imidazo[1,2-a]pyrazin-3-yl)-[1,1'-biphenyl]-3-carboxamides as Selective DDR1 Inhibitors.

Yong Xu, Xiaoyun Lu, Zheng-chao Tu, 2020, ACS medicinal chemistry letters.

Small molecule discoidin domain receptor kinase inhibitors and potential medical applications.

Xiaoyun Lu, Ke Ding, Yupeng Li, 2015, Journal of medicinal chemistry.

Nanoparticle‐Conjugate TLR7/8 Agonist Localized Immunotherapy Provokes Safe Antitumoral Responses

B. Lambrecht, J. Tavernier, B. D. De Geest, 2018, Advanced materials.

Lymph-Node-Targeted Immune Activation by Engineered Block Copolymer Amphiphiles-TLR7/8 Agonist Conjugates.

B. Lambrecht, B. D. De Geest, N. Sanders, 2018, Journal of the American Chemical Society.

Mass Spectrometry-Based Metabolic Profiling of Urinary Metabolites of N'-Nitrosonornicotine (NNN) in the Rat.

S. Hecht, S. Balbo, Yupeng Li, 2023, Chemical research in toxicology.

Discovery of a Potent, Cooperative, and Selective SOS1 PROTAC ZZ151 with In Vivo Antitumor Efficacy in KRAS-Mutant Cancers.

Yupeng Li, Guizhen Zhou, Tianfeng Xu, 2023, Journal of medicinal chemistry.

Small molecule discoidin domain receptor kinase inhibitors and potential medical applications.

Xiaoyun Lu, Ke Ding, Yupeng Li, 2015, Journal of medicinal chemistry.

DNA Adducts in Cancer Chemotherapy.

Yupeng Li, 2024, Journal of medicinal chemistry.