I. El-Deeb

发表

Synthesis of New N-Arylpyrimidin-2-amine Derivatives Using a Palladium Catalyst

J. Ryu, So Ha Lee, I. El-Deeb, 2008, Molecules.

Optical Gain Coefficient Measurements for 1-(4’-(Diphenylamino)-[1,1’-biphenyl]-4-yl)ethanone

F. Henari, I. El-Deeb, 2017 .

Curcumin–Copper Complex Nanoparticles for the Management of Triple-Negative Breast Cancer

K. Greish, V. Pittalà, S. Taurin, 2018, Nanomaterials.

A novel potential therapeutic avenue for autism: design, synthesis and pharmacophore generation of SSRIs with dual action.

D. A. Ibrahim, Ola M Ghoneim, So Ha Lee, 2011, Bioorganic & medicinal chemistry letters.

Anticancer effects of KI-10F: a novel compound affecting apoptosis, angiogenesis and cell growth in colon cancer.

Byung Sun Park, Soon-Sun Hong, Hong-Mei Zheng, 2012, International journal of oncology.

Cross-species malaria immunity induced by chemically attenuated parasites.

Dorela D. Shuboni-Mulligan, S. Hoffman, M. Batzloff, 2013, The Journal of clinical investigation.

New antiviral approaches for human parainfluenza: Inhibiting the haemagglutinin-neuraminidase.

M. von Itzstein, R. Thomson, I. El-Deeb, 2019, Antiviral research.

A New Efficient Convergent Synthesis of Conjugated Aryl-containing Dendrimers

So Ha Lee, I. El-Deeb, 2010 .

Neurodegenerative Disease Treatment Drug PBT2 Breaks Intrinsic Polymyxin Resistance in Gram-Positive Bacteria

M. Davies, A. McEwan, D. Paterson, 2022, Antibiotics.

Neisseria gonorrhoeae Becomes Susceptible to Polymyxin B and Colistin in the Presence of PBT2.

T. Haselhorst, M. von Itzstein, M. Jennings, 2019, ACS infectious diseases.

A drug candidate for Alzheimer's and Huntington's disease, PBT2, can be repurposed to render Neisseria gonorrhoeae susceptible to natural cationic antimicrobial peptides.

M. von Itzstein, M. Jennings, J. Edwards, 2021, The Journal of antimicrobial chemotherapy.

Rescuing Tetracycline Class Antibiotics for the Treatment of Multidrug-Resistant Acinetobacter baumannii Pulmonary Infection

S. Beatson, A. McEwan, D. Paterson, 2022, mBio.

Vaccination with chemically attenuated Plasmodium falciparum asexual blood-stage parasites induces parasite-specific cellular immune responses in malaria-naïve volunteers: a pilot study

S. Hoffman, Mei-Fong Ho, M. Good, 2018, BMC Medicine.

Multiple Bactericidal Mechanisms of the Zinc Ionophore PBT2

M. Brimble, M. von Itzstein, C. McDevitt, 2020, mSphere.

New Phenylaminopyrimidine (PAP) Anticancer Lead Compound with High Efficacy: Design, Synthesis, and in vitro Screening

D. Han, I. Kim, So Ha Lee, 2010 .

A versatile synthesis of "tafuramycin A": a potent anticancer and parasite attenuating agent.

Faith J. Rose, M. von Itzstein, P. Healy, 2014, Organic & biomolecular chemistry.

Exploring human parainfluenza virus type-1 hemagglutinin-neuraminidase as a target for inhibitor discovery.

T. Haselhorst, J. C. Dyason, M. von Itzstein, 2014, Journal of medicinal chemistry.

Repurposing the Ionophore, PBT2, for Treatment of Multidrug-Resistant Neisseria gonorrhoeae Infections

M. von Itzstein, J. Edwards, M. Walker, 2022, Antimicrobial agents and chemotherapy.

Design, synthesis and biological evaluation of new potent and highly selective ROS1-tyrosine kinase inhibitor.

Byung Sun Park, S. Cho, D. Han, 2009, Bioorganic & medicinal chemistry letters.

Design and synthesis of new potent anticancer pyrazoles with high FLT3 kinase inhibitory selectivity.

So Ha Lee, I. El-Deeb, 2010, Bioorganic & medicinal chemistry.

Design and synthesis of novel phenylaminopyrimidines with antiproliferative activity against colorectal cancer

A. M. Al-Abd, F. Al-Abbasi, I. El-Deeb, 2019, RSC advances.

Synthesis and antitumor evaluation of novel cyclic arylsulfonylureas: ADME-T and pharmacophore prediction.

I. El-Deeb, A. Abdel-Aziz, M. A. El-Sherbeny, 2010, European journal of medicinal chemistry.

Dysregulation of Streptococcus pneumoniae zinc homeostasis breaks ampicillin resistance in a pneumonia infection model

A. McEwan, M. Maher, A. Iverson, 2022, Cell reports.

Targeting Human Parainfluenza Virus Type-1 Haemagglutinin-Neuraminidase with Mechanism-Based Inhibitors

M. von Itzstein, I. El-Deeb, P. Guillon, 2019, Viruses.

The Catalytic Mechanism of Human Parainfluenza Virus Type 3 Haemagglutinin-Neuraminidase Revealed†

L. Chavas, M. Itzstein, Cindy J. Carroux, 2015 .

The impact of the butterfly effect on human parainfluenza virus haemagglutinin-neuraminidase inhibitor design

L. Chavas, M. Itzstein, I. El-Deeb, 2017, Scientific Reports.

Structure-guided discovery of potent and dual-acting human parainfluenza virus haemagglutinin–neuraminidase inhibitors

T. Haselhorst, J. C. Dyason, M. von Itzstein, 2014, Nature Communications.

ROS receptor tyrosine kinase: a new potential target for anticancer drugs

K. Yoo, So Ha Lee, I. El-Deeb, 2010, Medicinal research reviews.

Chemical Synergy between Ionophore PBT2 and Zinc Reverses Antibiotic Resistance

G. Dougan, M. Davies, A. McEwan, 2018, mBio.

Design, Synthesis and in-vitro Screening of New 1H-Pyrazole and 1,2-Isoxazole Derivatives as Potential Inhibitors for ROS and MAPK14 Kinases

M. M. Al-Sanea, So Ha Lee, I. El-Deeb, 2013 .

Synthesis and Biological Activity of New 4-(Pyridin-4-yl)-(3-methoxy-5-methylphenyl)-1H-pyrazoles Derivatives as ROS Receptor Tyrosine Kinase Inhibitors

Byung Sun Park, D. Han, K. Yoo, 2012 .

A Highly Selective Staurosporine Derivative Designed by a New Selectivity Filter

Byung Sun Park, D. Han, Kihang Choi, 2011 .

Design and synthesis of new anticancer pyrimidines with multiple-kinase inhibitory effect.

So Ha Lee, I. El-Deeb, 2010, Bioorganic & medicinal chemistry.

Exploring inhibitor structural features required to engage the 216-loop of human parainfluenza virus type-3 hemagglutinin-neuraminidase.

M. von Itzstein, I. El-Deeb, P. Guillon, 2017, MedChemComm.

Transcriptomic Data Sets To Determine Gene Expression Changes Mediated by the Presence of PBT2 in Growth Medium of Multidrug-Resistant Neisseria gonorrhoeae WHO Z

M. von Itzstein, M. Jennings, I. El-Deeb, 2020, Microbiology Resource Announcements.

Design, synthesis, screening, and molecular modeling study of a new series of ROS1 receptor tyrosine kinase inhibitors.

Byung Sun Park, S. Cho, D. Han, 2009, Bioorganic & medicinal chemistry letters.

Repurposing a neurodegenerative disease drug to treat Gram-negative antibiotic-resistant bacterial sepsis

S. Beatson, J. Lacey, M. Davies, 2020, Science Translational Medicine.

A dual drug regimen synergistically blocks human parainfluenza virus infection

R. Altmeyer, M. von Itzstein, I. El-Deeb, 2016, Scientific Reports.

Graphical Abstract

I. El-Deeb, So Ha Lee, 2011 .

The catalytic mechanism of human parainfluenza virus type 3 haemagglutinin-neuraminidase revealed.

L. Chavas, M. von Itzstein, Cindy J. Carroux, 2015, Angewandte Chemie.

Anticancer effects of KI-10F: a novel compound affecting apoptosis, angiogenesis and cell growth in colon cancer.

Byung Sun Park, Soon-Sun Hong, Hong-Mei Zheng, 2012, International journal of oncology.

Discovery of Cofactor Competitive Inhibitors against the Human Methyltransferase Fibrillarin

L. Hartley-Tassell, M. Itzstein, T. Ve, 2021, Pharmaceuticals.

Design and synthesis of new anticancer pyrimidines with multiple-kinase inhibitory effect.

So Ha Lee, I. El-Deeb, 2010, Bioorganic & medicinal chemistry.