Kohsuke Takeda

The ASK1-MAP kinase cascades in mammalian stress response.

H. Ichijo, K. Takeda, A. Matsuzawa, 2004, Journal of biochemistry.

Mammalian thioredoxin is a direct inhibitor of apoptosis signal‐regulating kinase (ASK) 1

Kohei Miyazono, K. Miyazono, M. Kawabata, 1998, The EMBO journal.

Roles of MAPKKK ASK1 in stress-induced cell death.

H. Ichijo, K. Takeda, H. Nishitoh, 2003, Cell structure and function.

ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats.

Kiyoshi Inoue, H. Ichijo, K. Takeda, 2002, Genes & development.

SOD1 as a molecular switch for initiating the homeostatic ER stress response under zinc deficiency.

H. Ichijo, K. Takeda, H. Nishitoh, 2013, Molecular cell.

Als-linked Mutant Sod1 Induces Er Stress-and Ask1-dependent Motor Neuron Death by Targeting Derlin-1 -induced Cell Death Remains Controversial. Here We Show That Sod1 Mut Specifically Interacted with Derlin-1, a Component of Endoplasmic Reticulum (er)-associated Degradation (erad) Machinery and Trig

Takanori Yokota, H. Ichijo, K. Takeda, 2022 .

ASK Family Proteins in Stress Response and Disease

H. Ichijo, K. Takeda, T. Fujisawa, 2007, Molecular biotechnology.

Mitochondrial phosphoglycerate mutase 5 uses alternate catalytic activity as a protein serine/threonine phosphatase to activate ASK1

Tohru Natsume, Yusuke Sekine, Hideyuki Kinoshita, 2009, Proceedings of the National Academy of Sciences.

Apoptosis signal-regulating kinase 1 and cyclin D1 compose a positive feedback loop contributing to tumor growth in gastric cancer

Kei Sakamoto, Masao Omata, Haruhiko Yoshida, 2010, Proceedings of the National Academy of Sciences.