Claudia Generaux

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Synergistic Effects of a GPR 119 Agonist with Metformin on Weight Loss in Diet-Induced Obese Mice

Lihong Chen, Judi A McNulty, J. Binz, 2015 .

Synergistic Effects of a GPR119 Agonist with Metformin on Weight Loss in Diet-Induced Obese Mice

Lihong Chen, Judi A McNulty, J. Binz, 2015, The Journal of Pharmacology and Experimental Therapeutics.

In Vitro and in Vivo Determination of Piperacillin Metabolism in Humans

K. Brouwer, A. Bridges, G. Ghibellini, 2007, Drug Metabolism and Disposition.

Effects of parasitic infection on the pharmacokinetics and disposition of pentamidine analogs

Claudia Generaux, 2010 .

Identification of potent, nonabsorbable agonists of the calcium-sensing receptor for GI-specific administration.

S. Roller, S. M. Sparks, Grace Chen, 2017, Bioorganic & medicinal chemistry letters.

Linking (Pyr)1apelin-13 pharmacokinetics to efficacy: Stabilization and measurement of a high clearance peptide in rodents.

Michael C. Myers, Rongan Zhang, P. Gargalovic, 2019, Analytical biochemistry.

Compartmental and Enzyme Kinetic Modeling To Elucidate the Biotransformation Pathway of a Centrally Acting Antitrypanosomal Prodrug

D. Boykin, D. Thakker, M. Paine, 2013, Drug Metabolism and Disposition.

Synthesis, DNA affinity, and antiprotozoal activity of linear dications: Terphenyl diamidines and analogues.

W. Wilson, D. Boykin, J. Hall, 2006, Journal of medicinal chemistry.

Diamidines for human African trypanosomiasis.

M. Barrett, H. D. de Koning, W. Wilson, 2010, Current opinion in investigational drugs.

Thoracic Lymph Duct Catheterization with a Venous Shunt in the Nonhuman Primate

V. Mendenhall, Claudia Generaux, A. Rose, 2021, Journal of investigative surgery : the official journal of the Academy of Surgical Research.

A Semiphysiologically Based Pharmacokinetic Modeling Approach to Predict the Dose-Exposure Relationship of an Antiparasitic Prodrug/Active Metabolite Pair

Harvey J. Clewell, Miyoung Yoon, Kim L. R. Brouwer, 2012, Drug Metabolism and Disposition.

Application of monoclonal antibodies to measure metabolism of an anti‐trypanosomal compound in vitro and in vivo

H. Reisner, R. Tidwell, Claudia Generaux, 2010, Journal of clinical laboratory analysis.

Design and preparation of N-linked hydroxypyridine-based APJ agonists.

P. Gargalovic, D. Gordon, R. Wexler, 2022, Bioorganic & medicinal chemistry letters.

In Vitro and In Vivo Evaluation of a Small-Molecule APJ (Apelin Receptor) Agonist, BMS-986224, as a Potential Treatment for Heart Failure

P. Gargalovic, M. Bouvier, D. Gordon, 2021, Circulation. Heart failure.

Identification of 6-Hydroxypyrimidin-4(1H)-one-3-carboxamides as Potent and Orally Active APJ Receptor Agonists.

P. Gargalovic, D. Gordon, R. Wexler, 2021, ACS medicinal chemistry letters.

Identification of 6-Hydroxy-5-phenylsulfonylpyrimidin-4(1H)-one APJ Receptor Agonists.

Michael A. Galella, P. Gargalovic, R. Wexler, 2021, Bioorganic & Medicinal Chemistry Letters.

Identification of nonabsorbable inhibitors of the scavenger receptor-BI (SR-BI) for tissue-specific administration.

J. Parham, S. M. Sparks, C. Jayawickreme, 2016, Bioorganic & medicinal chemistry letters.

Identification of a Hydroxypyrimidinone Compound (21) as a Potent APJ Receptor Agonist for the Potential Treatment of Heart Failure.

P. Gargalovic, R. Wexler, Tao Wang, 2021, Journal of medicinal chemistry.

Discovery of a Hydroxypyridinone APJ Receptor Agonist as a Clinical Candidate.

Michael A. Galella, P. Gargalovic, Soong-Hoon Kim, 2021, Journal of medicinal chemistry.

Lymphatic Distribution of Etanercept Following Intravenous and Subcutaneous Delivery to Rats

A. Kozhich, L. Kagan, Xizhe Gao, 2020, Pharmaceutical Research.