D. Buzard

发表

GPR119 agonists for the treatment of type 2 diabetes

Robert M. Jones, J. Leonard, D. Buzard, 2009, Expert opinion on therapeutic patents.

GPR119 agonists 2009-2011.

Robert M. Jones, D. Buzard, J. Lehmann, 2012, Pharmaceutical patent analyst.

Discovery of a novel trans-1,4-dioxycyclohexane GPR119 agonist series.

S. H. Kim, Michael E. Morgan, Robert M. Jones, 2015, Bioorganic & medicinal chemistry letters.

Discovery and optimization of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists.

S. H. Kim, Michael E. Morgan, K. Whelan, 2014, Bioorganic & medicinal chemistry letters.

C-H activation reactions as useful tools for medicinal chemists.

M. Urbano, Robert M. Jones, D. Buzard, 2016, Bioorganic & medicinal chemistry letters.

A modular route to nonracemic cyclo-NOBINs. Preparation of the parent ligand for homo- and heterogeneous catalysis

D. Buzard, B. Lipshutz, K. Noson, 2004 .

Kinetics of 5-HT2B Receptor Signaling: Profound Agonist-Dependent Effects on Signaling Onset and Duration

I. Gaidarov, John M Frazer, D. Unett, 2013, The Journal of Pharmacology and Experimental Therapeutics.

New Organometallic Solutions to Problems in Polyene Natural and Unnatural Product Synthesis

David P. Dickson, C. Lindsley, S. Pecchi, 1999 .

(7-Benzyloxy-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-yl)acetic Acids as S1P1 Functional Antagonists.

A. Blackburn, I. Gaidarov, S. H. Kim, 2014, ACS medicinal chemistry letters.

Fused tricyclic indoles as S1P₁ agonists with robust efficacy in animal models of autoimmune disease.

D. Sengupta, Michael E. Morgan, K. Whelan, 2012, Bioorganic & medicinal chemistry letters.

Alkylations of Functionalized Organozinc Reagents with Allylic Epoxides Catalyzed by A Cyanocuprate

K. Woo, D. Buzard, B. Lipshutz, 1997 .

Complementary asymmetric routes to (R)-2-(7-hydroxy-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-yl)acetate.

D. Sengupta, Robert M. Jones, D. Buzard, 2012, Organic letters.

Pd(0)-Mediated couplings of aryl nonaflates and triflates with diphenylphosphine-borane. Preparation of BH3-stabilized, unsymmetrical triarylphosphines

D. Buzard, B. Lipshutz, Chol Steve Yun, 1999 .

Synthesis of a broad array of highly functionalized, enantiomerically pure cyclohexanecarboxylic acid derivatives by microbial dihydroxylation of benzoic acid and subsequent oxidative and rearrangement reactions.

D. Siegel, A. Myers, D. Buzard, 2001, Organic letters.

Alkylations of Functionalized Organozinc Reagents with Allylic Epoxides Catalyzed by a Cyanocuprate.

K. Woo, D. Buzard, B. Lipshutz, 1997 .

An Electrospray Ionization Mass Spectrometry Study of the Aggregation States of Organocopper Complexes in Solution

D. Buzard, B. Lipshutz, J. Keith, 1999 .

Reductions of aryl perfluorosulfonates with dimethylamine · borane (Me2NH·BH3) catalyzed by Pd(0): an operationally simple, inexpensive, and general protocol

D. Buzard, B. Lipshutz, Randall W. Vivian, 1999 .

Therapeutic utility of cannabinoid receptor type 2 (CB(2)) selective agonists.

Robert M. Jones, D. Buzard, Sangdon Han, 2013, Journal of medicinal chemistry.

Recent progress in the development of selective S1P1 receptor agonists for the treatment of inflammatory and autoimmune disorders

Robert M. Jones, D. Buzard, J. Edwards, 2008 .

A New Bromo Trienyne: Synthesis of all-E, Conjugated Tetra-, Penta-, and Hexaenes Common to Oxo Polyene Macrolide Antibiotics.

David P. Dickson, C. Lindsley, S. Pecchi, 1998, The Journal of organic chemistry.

Discovery and characterization of potent and selective 4-oxo-4-(5-(5-phenyl-1,2,4-oxadiazol-3-yl)indolin-1-yl)butanoic acids as S1P₁ agonists.

C. Sage, Robert M. Jones, Yinghong Gao, 2011, Bioorganic & medicinal chemistry letters.

Discovery of APD334: Design of a Clinical Stage Functional Antagonist of the Sphingosine-1-phosphate-1 Receptor.

A. Blackburn, David Mills, I. Gaidarov, 2014, ACS medicinal chemistry letters.

Design and synthesis of new tricyclic indoles as potent modulators of the S1P1 receptor.

S. H. Kim, Robert M. Jones, Yinghong Gao, 2015, Bioorganic & medicinal chemistry letters.

An Efficient Scale-Up Process for the Preparation of the APD334 Precursor 4-Chloromethyl-1-cyclopentyl-2-(trifluoromethyl)benzene

Robert M. Jones, D. Sengupta, Robert M. Jones, 2015 .

Fused tricyclic indoles as S1P₁ agonists with robust efficacy in animal models of autoimmune disease.

D. Sengupta, Michael E. Morgan, K. Whelan, 2012, Bioorganic & medicinal chemistry letters.

Identification of 2-arylbenzimidazoles as potent human histamine H4 receptor ligands.

James P Edwards, Lars Karlsson, J Guy Breitenbucher, 2006, Bioorganic & medicinal chemistry letters.