B. Whittle

B. Whittle, 2002, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

Gastric mucosal damage induced by local intra‐arterial administration of Paf in the rat

J. Esplugues, B. Whittle, B. Whittle, 1988, British journal of pharmacology.

Picomole doses of platelet-activating factor predispose the gastric mucosa to damage by topical irritants.

J. Wallace, B. Whittle, 1986, Prostaglandins.

Potent ulcerogenic actions of platelet-activating factor on the stomach

J. Wallace, B. Whittle, A. Rosam, 1986, Nature.

Gastric Microvascular Effects of the Pro-ulcerogenic Mediator PAF-Acether

J. Esplugues, B. Whittle, P. Guth, 1988 .

Prostanoids and related mediators in gastric damage and disease

J. Wallace, B. Whittle, 1988 .

Profile of gastrointestinal damage induced by platelet-activating factor.

J. Wallace, B. Whittle, 1986, Prostaglandins.

Actions of nitric oxide on the acute gastrointestinal damage induced by PAF in the rat

N. Boughton-Smith, B. Whittle, A. Deakin, 2005, Agents and Actions.

Actions of nitric oxide on the acute gastrointestinal damage induced by PAF in the rat

N. Boughton-Smith, B. Whittle, A. Deakin, 2005, Agents and Actions.

Gastric damage following local intra‐arterial administration of reactive oxygen metabolites in the rat

J. Esplugues, B. Whittle, B. Whittle, 1989, British journal of pharmacology.

The role of nitric oxide and platelet-activating factor in the inhibition by endotoxin of pentagastrin-stimulated gastric acid secretion.

J. Esplugues, J. Piqué, M. Barrachina, 1992, European journal of pharmacology.

Gastrointestinal plasma leakage in endotoxic shock. Inhibition by prostaglandin E2 and by a platelet-activating factor antagonist.

J. Wallace, B. Whittle, G. Steel, 1987, Canadian journal of physiology and pharmacology.

Prevention of endotoxin-induced gastrointestinal damage by CV-3988, an antagonist of platelet-activating factor.

J. Wallace, B. Whittle, 1986, European journal of pharmacology.

Microvascular actions of platelet-activating factor on rat gastric mucosa and submucosa.

F. Leung, B. Whittle, P. Guth, 1986, The American journal of physiology.

Regulation of induction of nitric oxide synthase and the inhibitory actions of dexamethasone in the human intestinal epithelial cell line, Caco‐2: influence of cell differentiation

B. Whittle, M. Cavicchi, 1999, British journal of pharmacology.

Role of oxygen radicals and arachidonic acid metabolites in the reverse passive Arthus reaction and carrageenin paw oedema in the rat

N. Boughton-Smith, B. Whittle, L. G. Garland, 1993, British journal of pharmacology.

Interactions of pro-inflammatory and vasoactive mediators with nitric oxide in the regulation of rat vascular permeability during laparotomy.

I. Pávó, F. László, É. Morschl, 2000, European journal of pharmacology.

Role of nitric oxide and platelet-activating factor in the initiation of indomethacin-provoked intestinal inflammation in rats.

F. László, B. Whittle, 1998, European journal of pharmacology.

The modulation of IL-6 and TNF-alpha release by nitric oxide following stimulation of J774 cells with LPS and IFN-gamma.

S. Moncada, B. Whittle, A. Payne, 1995, Cytokine.

Modulators of Inducible Nitric Oxide Synthase: Potential Drugs for the Therapy of Gut Inflammation?

D. Lamarque, B. Whittle, M. Cavicchi, 2002 .

Carbacyclin--a potent stable prostacyclin analogue for the inhibition of platelet aggregation.

J. Vane, S. Moncada, F. Whiting, 1980, Prostaglandins.

Platelet actions of stable carbocyclic analogues of prostacyclin.

S. Moncada, B. Whittle, 1985, Circulation.

Nitric oxide donors increase mucus gel thickness in rat stomach.

J. F. Brown, B. Whittle, P. J. Hanson, 1992, European journal of pharmacology.

Biosynthesis of lipoxygenase and cyclo-oxygenase products from [14C]-arachidonic acid by human colonic mucosa.

C. Hawkey, N. Boughton-Smith, B. Whittle, 1983, Gut.

Synthesis of Hexahydrocyclopentimidazol-2-(1H)-one derivatives displaying selective DP-receptor agonist properties.

A. Robertson, C. Harris, P. Leff, 1996, Bioorganic & medicinal chemistry.

Synthesis and Inhibitory Activity on Platelet Aggregation of 13′‐Aza and Other ω‐Chain Modified BW245C Analogues

W. R. King, C. Harris, B. Whittle, 1994, Archiv der Pharmazie.

Interaction of prostaglandin D2 with prostacyclin, carbacyclin and the hydantoin prostaglandin, BW245C, in guinea‐pig platelets

B. Whittle, B. Whittle, S. Hamid, 1985, British journal of pharmacology.

Specificity between the anti-aggregatory actions of prostacyclin, prostaglandin E1 and D2 on platelets.

B. Whittle, P. Lidbury, A. Rosam, 1985, Advances in experimental medicine and biology.

The use of stable prostaglandins to investigate prostacyclin (PGI2)-binding sites and PGI2-sensitive adenylate cyclase in human platelet membranes.

J. Vane, S. Moncada, R. Paoletti, 1984, Prostaglandins.

Prostacyclin and its analogues for the therapy of thromboembolic disorders.

S. Moncada, B. Whittle, 1984, Advances in experimental medicine and biology.

Platelet and cardiovascular activity of the hydantoin BW245C, a potent prostaglandin analogue.

J. Vane, S. Moncada, K. Mullane, 1983, Prostaglandins.

Relative potency of prostacyclin, prostaglandin E1 and D2 as inhibitors of platelet aggregation in several species [proceedings].

J. Vane, S. Moncada, B. Whittle, 1977, The Journal of physiology.

Colorectal leukotriene B4 synthesis in vitro in inflammatory bowel disease: inhibition by the selective 5-lipoxygenase inhibitor BWA4C.

C. Hawkey, N. Boughton-Smith, A. Hawthorne, 1992, Gut.

Role of bacteria and inducible nitric oxide synthase activity in the systemic inflammatory microvascular response provoked by indomethacin in the rat.

B. Whittle, S. Evans, 2003, European journal of pharmacology.

Pharmacological interactions between prostacyclin and thromboxanes.

S. Moncada, B. Whittle, 1983, British medical bulletin.

Nitric oxide modulates the gastrointestinal plasma extravasation following intraabdominal surgical manipulation in rats.

I. Pávó, F. László, É. Morschl, 1999, European journal of pharmacology.

Attenuation by nitrosothiol NO donors of acute intestinal microvascular dysfunction in the rat

S. Moncada, F. László, B. Whittle, 1995, British journal of pharmacology.

Modulation of human colonic arachidonic acid metabolism by sulfasalazine

C. Hawkey, N. Boughton-Smith, B. Whittle, 1985, Digestive Diseases and Sciences.

Biological actions of prostacyclin and its pharmacological use in platelet studies.

S. Moncada, B. Whittle, 1985, Advances in experimental medicine and biology.

Detrimental effects of oestradiol on cysteamine-induced gastroduodenal ulceration in the female rat

I. Pávó, F. László, Z. Szepes, 1999, Journal of Physiology-Paris.

Biosynthesis of endogenous arachidonate products involved in gastric damage and protection

N. Boughton-Smith, B. Whittle, 1984 .

GW273629 is a highly selective, short-acting iNOS (NOS-2) inhibitor both in vitro and in vivo: beneficial effects in endotoxin shock

Richard Graham Knowles, S. Moncada, E. Garvey, 2000 .

The role of leukotrienes in the pathogenesis of gastric ulceration.

N. Boughton-Smith, B. Whittle, 1988, Pharmacological research communications.

Laboratory methods for studying the role of eicosanoids in inflammatory bowel disease

N. Boughton-Smith, B. Whittle, 1988 .

Involvement of endogenous nitric oxide in the inhibition by endotoxin and interleukin‐1β of gastric acid secretion

J. Esplugues, S. Calatayud, M. Barrachina, 1994, Journal of gastroenterology and hepatology.

Increase In Gastric Intramucosal Hydrogen Ion Concentration Following Endotoxin Challenge In The Rat And The Actions Of Nitric Oxide Synthase Inhibitors

D. Lamarque, B. Whittle, Brendan Jr Whittle, 2001, Clinical and experimental pharmacology & physiology.

Lipopolysaccharide induces Ca2+-independent nitric oxide synthase activity in rat gastric mucosal cells

B. Tepperman, B. Whittle, P. J. Hanson, 1994 .

Role of mucus in the repair of gastric epithelial damage in the rat

J. Wallace, B. Whittle, 1986 .

Modulation by prostanoids of the release of inflammatory mediators from mast cells: involvement in mucosal protection?

B. Whittle, 1993, Gastroenterology.

Arachidonic acid metabolites and the gastro-intestinal toxicity of anti-inflammatory agents.

B. Whittle, 1981, Prostaglandins.

Use of the rabbit transverse stomach-strip to identify and assay prostacyclin, PGA2, PGD2 and other prostaglandins.

S. Moncada, B. Whittle, K. Mugridge, 1979, European journal of pharmacology.

Effects of prostaglandin E2 methyl analogues on the anti‐inflammatory and gastric erosive activity of indomethacin

L. Youlten, E. McCall, B. Whittle, 1976, The Journal of pharmacy and pharmacology.

Involvement of peroxynitrite in the lipid peroxidation induced by nitric oxide in rat gastric mucosa

D. Lamarque, B. Whittle, 1996 .

Temporal relationship between cyclooxygenase inhibition, as measured by prostacyclin biosynthesis, and the gastrointestinal damage induced by indomethacin in the rat.

B. Whittle, 1981, Gastroenterology.

Opioid-sensitive peripheral neuronal activity in the modulation of gastric mucosal injury.

J. Esplugues, B. Whittle, 1991, Advances in experimental medicine and biology.

The cardiovascular and platelet actions of 9β‐methyl carbacyclin (ciprostene), a chemically stable analogue of prostacyclin, in the dog and monkey

P. Oliver, B. Whittle, G. Allan, 1985, British journal of pharmacology.

Failure of the inhibition of rat gastric mucosal 5‐lipoxygenase by novel acetohydroxamic acids to prevent ethanol‐induced damage

N. Boughton-Smith, B. Whittle, B.J.R. Whittle, 1988, British journal of pharmacology.

Gastric vasoconstrictor actions of leukotriene C4, PGF2 alpha, and thromboxane mimetic U-46619 on rat submucosal microcirculation in vivo.

B. Whittle, P. Guth, N. Oren-Wolman, 1985, The American journal of physiology.

Actions of prostacyclin (PGI2) and its product, 6-oxo-PGF1alpha on the rat gastric mucosa in vivo and in vitro.

J. Vane, S. Moncada, N. Boughton-Smith, 1978, Prostaglandins.

Advances In Drug Therapy Of Gastrointestinal Ulceration

B. Whittle, A. Garner, 1989 .

Assessment of the actions of prostanoids in the protection and repair of the gastric mucosa.

J. Wallace, B. Whittle, G. Steel, 1986, Scandinavian journal of gastroenterology. Supplement.

Prostacyclin-sensitive adenylate cyclase in cultured myocytes: differences between rabbit aorta and mesenteric artery.

J. Vane, S. Moncada, F. Bernini, 1984, European journal of pharmacology.

Prostacyclin analogues inhibit canine parietal cell activity and cyclic AMP formation.

B. Whittle, A. Soll, 1981, Prostaglandins.

New light on the anti-colitic actions of therapeutic aminosalicylates: the role of heme oxygenase

B. Whittle, C. Varga, 2010, Pharmacological reports : PR.

Assessment of anticolitic drugs in the trinitrobenzene sulfonic acid (TNBS) rat model of inflammatory bowel disease.

D. Lamarque, B. Whittle, M. Cavicchi, 2003, Methods in molecular biology.

Rapid induction of the antioxidant, heme oxygenase-1 (HO-1) in human intestinal epithelial cells: Interaction with glutathione levels

D. Lamarque, B. Whittle, C. Varga, 2001 .

Heme oxygenase-1 (HO-l) induction in human intestinal epithelial cells by sulphasalazine and 5-aminosalicylic acid: A potential therapeutic mechanism

L. Gibbs, B. Whittle, M. Cavicchi, 2000 .

Synthesis of nitric oxide from L-arginine by neutrophils. Release and interaction with superoxide anion.

S. Moncada, R. Palmer, N. Boughton-Smith, 1989, The Biochemical journal.

Cyclooxygenase and nitric oxide systems in the gut as therapeutic targets for safer anti-inflammatory drugs.

B. Whittle, 2004, Current opinion in pharmacology.

Modulation by nitric oxide of spontaneous motility of the rat isolated duodenum: role of tachykinins

J. Esplugues, B. Whittle, M. Martínez-Cuesta, 1996, British journal of pharmacology.

Selective inhibition of prostaglandin production in inflammatory exudates and gastric mucosa

J. Vane, S. Moncada, B. Whittle, 1980, Nature.

Synthesis and Platelet Aggregation Inhibiting Activity of Acid Side‐chain Modified Hydantoin Prostaglandin Analogues

R. Glen, C. Harris, N. Whittaker, 1993, Archiv der Pharmazie.

Nitric oxide synthase activity in ulcerative colitis and Crohn's disease

C. Hawkey, M. Balsitis, S. Moncada, 1993, The Lancet.

Nitric oxide synthase activity, viability and cyclic GMP levels in rat colonic epithelial cells: effect of endotoxin challenge.

J. F. Brown, B. Tepperman, B. Whittle, 1994, The Journal of pharmacology and experimental therapeutics.

Failure of prostaglandin E2 and its 16,16‐dimethyl analogue to prevent the gastric mucosal damage induced by Paf

J. Wallace, B. Whittle, G. Steel, 1987, British journal of pharmacology.

Evaluation of the protection of rat gastric mucosa by a prostaglandin analogue using cellular enzyme marker and histologic techniques.

B. Whittle, G. Steel, 1985, Gastroenterology.

Gastrointestinal actions of carbacyclin, a stable mimic of prostacyclin

N. Boughton-Smith, B. Whittle, G. Steel, 1980, The Journal of pharmacy and pharmacology.

Relationship between the prevention of rat gastric erosions and the inhibition of acid secretion by prostaglandins.

B. Whittle, 1976, European journal of pharmacology.

Role of prostanoids in the protective actions of BW755C on the gastric mucosa.

J. Wallace, B. Whittle, 1985, European journal of pharmacology.

Differential distribution of nitric oxide synthase between cell fractions isolated from the rat gastric mucosa.

J. F. Brown, S. Moncada, B. Tepperman, 1992, Biochemical and biophysical research communications.

The vasodilator role of endogenous nitric oxide in the rat gastric microcirculation.

J. Esplugues, J. Piqué, B. Whittle, 1989, European journal of pharmacology.

1400W Is a Slow, Tight Binding, and Highly Selective Inhibitor of Inducible Nitric-oxide Synthase in Vitro and in Vivo*

Richard Graham Knowles, E. Garvey, E. Furfine, 1997, The Journal of Biological Chemistry.

Site-specific lesion formation, inflammation and inducible nitric oxide synthase expression by indomethacin in the rat intestine.

F. László, B. Whittle, S. Evans, 2000, European journal of pharmacology.

Neuronal and endothelium‐derived mediators in the modulation of the gastric microcirculation: integrity in the balance

B. Whittle, 1993, British journal of pharmacology.

Nitric Oxide and the Gastrointestinal Tract

B. Whittle, 1993 .

Biosynthesis and Role of the Endothelium‐Derived Vasodilator, Nitric Oxide, in the Gastric Mucosa

S. Moncada, N. Boughton-Smith, B. Whittle, 1992, Annals of the New York Academy of Sciences.

Polyethylene Glycol Conjugation of Protein and Small Molecule Drugs

B. Whittle, R. Shorr, Michael Bentley, 2004 .

Modulation by heme and zinc protoporphyrin of colonic heme oxygenase-1 and experimental inflammatory bowel disease in the rat.

P. Fritz, F. László, D. Lamarque, 2007, European journal of pharmacology.

Gastric ulcer formation and cyclo-oxygenase inhibition in cat antrum follows parenteral administration of aspirin but not salicylate.

J. Salmon, B. Whittle, D. Hansen, 1985, European journal of pharmacology.

Endotoxin can decrease isolated rat parotid acinar cell amylase secretion in a nitric oxide-independent manner.

Á. Kittel, T. Zelles, A. Kovács, 2005, European journal of pharmacology.

Prostaglandin protection of rat colonic mucosa from damage induced by ethanol

J. Wallace, N. Boughton-Smith, B. Whittle, 1985, Digestive Diseases and Sciences.

Microsomal Prostaglandin E Synthase-1 Expression in Inflammatory Conditions Is Downregulated by Dexamethasone: Seminal Role of the Regulatory Phosphatase MKP-1

E. Moilanen, B. Whittle, M. Hämäläinen, 2017, Front. Pharmacol..

Endogenous nitric oxide as a mediator of gastric mucosal vasodilatation during acid secretion.

J. Esplugues, J. Piqué, B. Whittle, 1992, Gastroenterology.

Effects of prostacyclin and a stable analogue, 6β-PGI1, on gastric acid secretion, mucosal blood flow, and blood pressure in conscious dogs

J. Vane, B. Whittle, G. Kauffman, 1979 .

The Pharmacological Background

J. Salmon, R. Ferris, B. Whittle, 2020, Early Phase Drug Evaluation in Man.

THE GASTRIC ANTISECRETORY ACTIONS OF PROSTAGLANDIN E2 AND STABLE PROSTACYCLIN ANALOGUES AGAINST DIFFERENT SECRETAGOGUES IN PERFUSED WHOLE‐STOMACHS OF RAT OR MOUSE in vitro

N. Boughton-Smith, B. Whittle, 1981, British journal of pharmacology.

Helicobacter pylori lipopolysaccharide provokes iNOS-mediated acute systemic microvascular inflammatory responses in rat cardiac, hepatic, renal and pulmonary tissues

A. Moran, F. László, É. Morschl, 2001, Journal of Physiology-Paris.

Helicobacter pylori lipopolysaccharide-provoked injury to rat gastroduodenal microvasculature involves inducible nitric oxide synthase.

A. Moran, F. László, É. Morschl, 2001, European journal of pharmacology.

The induction of nitric oxide synthase and intestinal vascular permeability by endotoxin in the rat

S. Moncada, N. Boughton-Smith, B. Whittle, 1993, British journal of pharmacology.

Cytotoxicity associated with induction of nitric oxide synthase in rat duodenal epithelial cells in vivo by lipopolysaccharide of Helicobacter pylori: inhibition by superoxide dismutase

A. Moran, Z. Szepes, D. Lamarque, 2000, British journal of pharmacology.

Induction of nitric oxide synthase in vivo and cell injury in rat duodenal epithelium by a water soluble extract of Helicobacter pylori

D. Lamarque, B. Whittle, J. Delchier, 1998, British journal of pharmacology.

Association of microvascular leakage with induction of nitric oxide synthase: effects of nitric oxide synthase inhibitors in various organs.

S. Moncada, F. László, B. Whittle, 1995, European journal of pharmacology.

Interactive roles of superoxide and inducible nitric oxide synthase in rat intestinal injury provoked by non-steroidal anti-inflammatory drugs.

B. Whittle, S. Evans, 2001, European journal of pharmacology.

Induction of nitric oxide synthase and microvascular injury in the rat jejunum provoked by indomethacin

S. Moncada, B. Whittle, S. Evans, 1995, British journal of pharmacology.

Aminoguanidine inhibits both constitutive and inducible nitric oxide synthase isoforms in rat intestinal microvasculature in vivo.

F. László, B. Whittle, S. Evans, 1995, European journal of pharmacology.

The role of extracellular mucus as a protective cap over gastric mucosal damage.

J. Wallace, B. Whittle, 1986, Scandinavian journal of gastroenterology. Supplement.

Role of nitric oxide in maintaining vascular integrity in endotoxin‐induced acute intestinal damage in the rat

N. Boughton-Smith, B. Whittle, I. R. Hutcheson, 1990, British journal of pharmacology.

Inhibitory effects of histamine H4 receptor antagonists on experimental colitis in the rat.

R. Thurmond, B. Whittle, C. Varga, 2005, European journal of pharmacology.

Nitric oxide in physiology and pathology

B. Whittle, 1995, The Histochemical Journal.

Nitric oxide in physiology and pathology

B. Whittle, 2004, The Histochemical Journal.

Inhibition of gastric acid secretion by stress: a protective reflex mediated by cerebral nitric oxide.

J. Esplugues, S. Moncada, S. Calatayud, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Nitric oxide--a mediator of inflammation or mucosal defence.

B. Whittle, Brendan J.r. Whittle, B. Whittle, 1997, European journal of gastroenterology & hepatology.

Involvement of endogenous nitric oxide in the regulation of rat intestinal motility in vivo.

S. Moncada, A. Calignano, M. Di Rosa, 1992, European journal of pharmacology.

Immediate anaphylactic bronchoconstriction induces airway hyperreactivity in anaesthetized guinea‐pigs

B. Whittle, B. Whittle, L. Daffonchio, 1988, British journal of pharmacology.

Actions of Selective and Non-selective Nitric Oxide Synthase Inhibitors on Multiple-Organ Microvacular Injury Provoked by Lipopolysaccharide

F. László, B. Whittle, 1999 .

Mechanisms contributing to gastric motility changes induced by PAF-acether and endotoxin in rats.

J. Esplugues, B. Whittle, 1989, The American journal of physiology.

Evidence for platelet-activating factor as a mediator of endotoxin-induced gastrointestinal damage in the rat. Effects of three platelet-activating factor antagonists.

J. Wallace, B. Vargaftig, V. Lagente, 1987, Gastroenterology.

Gastric vascular actions of prostanoids and the dual effect of arachidonic acid.

B. Whittle, G. Kauffman, 1982, The American journal of physiology.

Formation of prostacyclin and its product 6-oxo-PGF1alpha by the gastric mucosa of several species [proceedings].

J. Salmon, J. Vane, S. Moncada, 1978, The Journal of physiology.

Induction of nitric oxide synthase in rat intestine and its association with tissue injury

S. Moncada, N. Boughton-Smith, B. Whittle, 2005, Agents and Actions.

Nitric oxide: The elusive mediator of the hyperdynamic circulation of cirrhosis?

S. Moncada, B. Whittle, Brendan J. R. Whittle, 1992, Hepatology.

Acceleration of recovery of gastric epithelial integrity by 16,16‐dimethyl prostaglandin E2

J. Wallace, B. Whittle, 1985, British journal of pharmacology.

Nitric oxide mediates rat mucosal vasodilatation induced by intragastric capsaicin.

S. Moncada, J. López-Belmonte, B. Whittle, 1992, European journal of pharmacology.

Close-arterial administration of the thromboxane mimetic U-46619 induces damage to the rat gastric mucosa.

J. Esplugues, B. Whittle, 1988, Prostaglandins.

Interaction between prostaglandins and cyclic AMP in the gastric mucosa.

B. Whittle, A. Soll, 1981, Prostaglandins.

Hemostatic mechanisms, independent of platelet aggregation, arrest gastric mucosal bleeding.

S. Moncada, B. Whittle, G. Kauffman, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Ulceration induced by an endoperoxide analog and by indomethacin in the canine stomach.

S. Moncada, B. Whittle, 1983, Advances in prostaglandin, thromboxane, and leukotriene research.

Gastric Venous Prostaglandin Concentrations during Basal and Stimulated Acid Secretion in Dog

J. Salmon, B. Whittle, G. Kauffman, 1982, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Localization of constitutive isoforms of nitric oxide synthase in the gastric glandular mucosa of the rat

B. Whittle, P. J. Hanson, K. Price, 1996, Cell and Tissue Research.

Protective effect of S-nitroso-N-acetyl-penicillamine in endotoxin-induced acute intestinal damage in the rat.

S. Moncada, I. Hutcheson, N. Boughton-Smith, 1990, European journal of pharmacology.

Stimulation by carbachol of mucus gel thickness in rat stomach involves nitric oxide.

B. Whittle, K J Price, P J Hanson, 1994, European journal of pharmacology.

The nitric oxide donor, S-nitroso-N-acetyl-penicillamine, inhibits secretory activity in rat isolated parietal cells.

J. F. Brown, B. Whittle, P. J. Hanson, 1993, Biochemical and biophysical research communications.

Nitric oxide donors preferentially inhibit neuronally mediated rat gastric acid secretion.

S. Moncada, S. Calatayud, B. Whittle, 1994, European journal of pharmacology.

Endogenous bacteria-triggered inducible nitric oxide synthase activation protects the ovariectomized rat stomach

I. Pávó, É. Morschl, G. Varga, 2001, Journal of Physiology-Paris.

Nitric oxide and sensory afferent neurones modulate the protective effects of low-dose endotoxin on rat gastric mucosal damage.

J. Esplugues, S. Calatayud, B. Whittle, 1995, European journal of pharmacology.

Lymphocytic infiltration and expression of inducible nitric oxide synthase in human duodenal and colonic mucosa is a characteristic feature of ankylosing spondylitis.

M. Breban, J. Nhieu, Z. Szepes, 2003, The Journal of rheumatology.

Beneficial effect of P54, A novel curcumin preparation in Tnbs-induced colitis in rats

Dominique Lamarque, D. Lamarque, B. Whittle, 2001 .

The modulation of IL-6 and TNF-α release by nitric oxide following stimulation of J774 cells with LPS and IFN-γ

Salvador Moncada, S. Moncada, B. Whittle, 1995 .

Characterisation of nitric oxide synthase activity in the rat colonic mucosa and muscle after endotoxin and in a model of colitis

N. Boughton-Smith, B. Whittle, S. Evans, 1994, Agents and Actions.

Colonic microvascular integrity in acute endotoxaemia: interactions between constitutive nitric oxide and 5-lipoxygenase products.

F. László, B. Whittle, 1995, European journal of pharmacology.

Cardiopulmonary and Gastric Ulcerogenic Actions of Endothelin‐1 in the Guinea Pig and Rat

J. Esplugues, B. Whittle, A. Payne, 1989, Journal of cardiovascular pharmacology.

Nitric oxide and the gut injury induced by non-steroidal anti-in ammatory drugs

B. Whittle, 2022 .

The relative activity of prostacyclin (PGI2) and a stable analogue 6β‐PGI1 on the gastrointestinal and cardiovascular systems

J. Vane, S. Moncada, N. Boughton-Smith, 1978, The Journal of pharmacy and pharmacology.

Activity of prostacyclin, a stable analogue, 61&-PGI1 and 6-oxo-PGFiaon canine isolated parietal cells

B. Whittle, A. Soll, 2007 .

Indomethacin potentiates endotoxin‐induced blood flow reduction and histological injury in rat gastric mucosa

Y. Yonei, F. Leung, J. Piqué, 1988, British journal of pharmacology.

Inhibition by 16,16-dimethyl PGE2 of ethanol-induced gastric mucosal damage and leukotriene B4 and C4 formation.

N. Boughton-Smith, B. Whittle, 1988, Prostaglandins.

Pharmacological modulation of bronchial anaphylaxis induced by aerosol challenge in anaesthetized guinea‐pigs

B. Whittle, B. Whittle, L. Daffonchio, 1987, British journal of pharmacology.

The differential response of a novel bioassay tissue, the rabbit transverse stomach-strip, to prostacyclin (PGI2) and other prostaglandins [proceedings].

S. Moncada, B. Whittle, K. Mugridge, 1977, British journal of pharmacology.

Attenuation of Helicobacter pylori endotoxin-provoked rat intestinal inflammation by selective inhibition of the inducible nitric oxide synthase

A. Moran, Z. Szepes, É. Morschl, 2001, Journal of Physiology-Paris.

Stimulation of gastric alkaline secretion by stable prostacyclin analogues in rat and dog.

N. Boughton-Smith, B. Whittle, G. Kauffman, 1984, European journal of pharmacology.

Nitric oxide mediates the inhibition by interleukin‐1β of pentagastrin‐stimulated rat gastric acid secretion

J. Esplugues, S. Calatayud, J. Piqué, 1993 .

Nitric oxide mediates the inhibition by interleukin-1 beta of pentagastrin-stimulated rat gastric acid secretion.

J. Esplugues, S. Calatayud, J. Piqué, 1993, British Journal of Pharmacology.

Involvement of neuronal processes and nitric oxide in the inhibition by endotoxin of pentagastrin-stimulated sastric acid secretion

J. Esplugues, J. Piqué, M. Barrachina, 1994, Naunyn-Schmiedeberg's Archives of Pharmacology.

Endogenous nitric oxide in the maintenance of rat microvascular integrity against widespread plasma leakage following abdominal laparotomy

B. Whittle, F. László, 1999, British journal of pharmacology.

Relationship between arachidonic acid metabolism, myeloperoxidase activity and leukocyte infiltration in a rat model of inflammatory bowel disease

J. Wallace, N. Boughton-Smith, B. Whittle, 1988, Agents and Actions.

Activity of prostacyclin, a stable analogue, 6 beta-PGI1 and 6-oxo-PGF1 alpha on canine isolated parietal cells [proceedings].

B. Whittle, A. Soll, 1979, British Journal of Pharmacology.

Time‐dependent enhancement or inhibition of endotoxin‐induced vascular injury in rat intestine by nitric oxide synthase inhibitors

S. Moncada, F. László, B. Whittle, 1994, British journal of pharmacology.

Platelet actions of stable carbocyclic analogues of prostacyclin.

S. Moncada, B. Whittle, 1985, Circulation.

Prostanoid EP2 Receptors Are Up-Regulated in Human Pulmonary Arterial Hypertension: A Key Anti-Proliferative Target for Treprostinil in Smooth Muscle Cells

A. Silverstein, R. McAnulty, X. Norel, 2018, International journal of molecular sciences.

Protocols to assess the gastrointestinal side effects resulting from inhibition of cyclo-oxygenase isoforms.

B. Whittle, 2010, Methods in molecular biology.

Induction of rat gastric damage by the endothelium‐derived peptide, endothelin

J. Esplugues, B. Whittle, B. Whittle, 1988, British journal of pharmacology.

Early phase microvascular interactions in rat jejunum between nitric oxide and vasopressin following indomethacin administration

F. László, B. Whittle, 1998 .

Early phase microvascular interactions in rat jejunum between nitric oxide and vasopressin following indomethacin administration

B. Whittle, Ferenc Lászloa, 1998, Journal of gastroenterology and hepatology.

Inducible nitric oxide synthase attenuates chronic colitis in human histocompatibility antigen HLA-B27/human beta2 microglobulin transgenic rats.

M. Breban, J. Nhieu, Z. Szepes, 2001, European cytokine network.