J. Caen

Y. Legrand, J. Caen, L. Robert, 1968, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Suppression of tumor growth by viral vector-mediated gene transfer of N-terminal truncated platelet factor 4.

Yixin Jin, Z. Han, Yanhan Li, 2003, Cancer biotherapy & radiopharmaceuticals.

Abnormal platelet function, population, and survival-time in a boy with congenital absent radii and thrombocytopenia.

Y. Sultan, F. Rendu, J. Caen, 1972, Lancet.

Studies of in vitro megakaryocytopoiesis in adult immune thrombocytopenic purpura (ITP)

Z. Han, S. Bellucci, J. Caen, 1991, European journal of haematology.

Megakaryocytopoiesis: characterization and regulation in normal and pathologic states.

Z. Han, S. Bellucci, J. Caen, 1991, International journal of hematology.

Quantitation of megakaryocytopoiesis by computerized automatic in culture image analysis.

C. Bal dit Sollier, Z. Han, J. Caen, 1998, Platelets.

Abnormal phosphoinositide metabolism and protein phosphorylation in platelets from a patient with the grey platelet syndrome

J. Maclouf, T. Hovig, M. Lebret, 1987, British journal of haematology.

Thrombin-Induced Platelet Factor Va Formation in Patients with a Gray Platelet Syndrome

D. Baruch, E. Dupuy, J. Caen, 1987, Thrombosis and Haemostasis.

ABNORMAL CALCIUM TRANSPORT INTO MICROSOMES OF GRAY PLATELET SYNDROME

M. Lebret, J. Caen, R. Bredoux, 1987, Thrombosis and Haemostasis.

Molecular membrane organization in normal and pathological platelets: changes in inositide metabolism and membrane fluidity.

J. Viret, F. Rendu, J. Caen, 1985, Nouvelle revue francaise d'hematologie.

Identification of the platelet alloantigen (PlA1) in circulating immune complexes of normal human sera

J. Wautier, B. Boizard, J. Caen, 2004, Cancer Immunology, Immunotherapy.

Histochemical and ultrastructural characterization of subendothelial glycoprotein microfibrils interacting with platelets.

P. Birembaut, M. Bélair, J. Bariéty, 1982, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Hypercalcemia in chronic myelogenous leukemia: evidence for excessive parathyroid hormone secretion.

J. Ballet, J. Wautier, J. Guéris, 1985, Nouvelle revue francaise d'hematologie.

Platelet factor 4 and other CXC chemokines support the survival of normal hematopoietic cells and reduce the chemosensitivity of cells to cytotoxic agents.

Z. Han, J. Caen, N. Schlegel, 1997, Blood.

Further Studies on a Specific Platelet Antibody Found in Bernard‐Soulier Syndrome and its Effects on Normal Platelet Function

C. Malmsten, A. Nurden, L. Degos, 1979, British journal of haematology.

Abnormal Platelets as Models for Understanding the Mechanisms of Platelet Function

A. Nurden, F. Rendu, G. Tobelem, 1979 .

[The receptor of adenosine-dephosphate on the human platelet membrane (author's translation)].

C. Legrand, J. Caen, 1976, Nouvelle revue francaise d'hematologie.

Role of Surface Glycoproteins in Human Platelet Function

A. Nurden, J. Caen, 1976, Thrombosis and Haemostasis.

Binding of 14C-ADP by thrombasthenic platelet membranes.

C. Legrand, J. Caen, 1976, Haemostasis.

Evidence that a collagen-derived nonapeptide is a specific inhibitor of platelet-collagen interaction.

A. Karniguian, Y. Legrand, J. Caen, 1980, Biochemical and biophysical research communications.

Platelet shape change: induction by trypsin and release of an acidic macroglycopeptide from washed human platelets and from those of three cases of Glanzmann's thrombasthenia.

J. Caen, R. Bredoux, A. Nurden, 1974, Haemostasis.

Platelet aggregation: its relation with ADP-induced fibrinogen binding to platelets and ADP-related membrane enzyme activities.

C. Legrand, J. Caen, V. Dubernard, 1984, European journal of biochemistry.

Further Studies on the Glycoprotein Composition of Normal Human, Bernard-Soulier and Thrombasthenic Platelets

A. Nurden, J. Caen, 1977, Thrombosis and Haemostasis.

Evidence that a collagen derived octapeptide inhibits fibrinogen binding to platelets stimulated by collagen and not by ADP.

C. Legrand, A. Karniguian, Y. Legrand, 1985, Biochemical and Biophysical Research Communications - BBRC.

General and Local Factors in Arterial Thrombosis: Platelets, Prostaglandins and Postulates

J. Maclouf, J. Caen, 1984 .

Specific and quantitative method for estimation of platelet adhesion to fibrillar collagen.

J. Wautier, Y. Legrand, J. Caen, 1979, Journal of Laboratory and Clinical Medicine.

Platelet adhesion to type III collagen: Involvement of a sequence of nine aminoacids from α1(III)CB4 peptide

Y. Legrand, J. Caen, P. Fietzek, 1979 .

Platelet-collagen interaction: adhesion of human blood platelets to purified (CB4) peptide from type III collagen.

Y. Legrand, J. Caen, P. Fietzek, 1978, Thrombosis research.

Evidence that the Monoclonal Antibody an 51 is Directed Against Platelet Membrane Glycoprotein IB

A. McMichael, N. Kieffer, G. Tobelem, 1983 .

Monoclonal Antibodies and Platelet Functions

G. Tobelem, J. Caen, 1983 .

Adenosine diphosphate metabolism by cultured human umbilical endothelial cells

B. Escoubet, J. Caen, A. Dosne, 1979, FEBS Letters.

Fibrinogen Dusart: electron microscopy of molecules, fibers and clots, and viscoelastic properties of clots.

J. Soria, C. Soria, J. Weisel, 1996, Biophysical journal.

Rapid evolution in the immunochemical findings of a gamma heavy chain disease.

C. Dosquet, J. Caen, F. Pontet, 1988, Clinical chemistry.

[Hemostasis and cancer].

G. Tobelem, J. Caen, L. Israel, 1974, Pathologie-biologie.

Interaction of blood platelets with a microfibrillar extract from adult bovine aorta: requirement for von Willebrand factor.

D. Jackson, G. Tobelem, Y. Legrand, 1983, Proceedings of the National Academy of Sciences of the United States of America.

C1 and human platelets. III. Role of C1 subcomponents in platelet aggregation induced by aggregated IgG.

J. Wautier, J. Caen, H. Souchon, 1976, Immunology.

Mg plus plus- and Ca plus plus-induced platelet aggregation and ADP.

J. Caen, S. Cronberg, 1970, Thrombosis et diathesis haemorrhagica.

Mg++ - and Ca++-Induced Platelet Aggregation and ADP

J. Caen, S. Cronberg, 1970 .

Further characterization of human platelet ADP binding sites using 5' AMP. Demonstration of a highly reactive population of sites.

C. Legrand, J. Caen, V. Dubernard, 1980, Biochemical and biophysical research communications.

Interaction of adenosine and adenylnucleotides with the human platelet membrane. Further characterization of the ADP binding sites.

C. Legrand, B. Bauvois, J. Caen, 1980, Haemostasis.

Haemophilia in a Female

Y. Sultan, J. Caen, J. McBride, 1971, Thrombosis and Haemostasis.

In Vitro and in Vivo Antithrombotic Effect of a Collagen-Derived Octapeptide

J. Soria, C. Soria, J. Fareed, 1987 .

Increased interaction of vascular endothelium and leucocytes after administration of antiplatelet serum: role in the developing vascular defect.

I. Kovács, J. Caen, 1979, Journal of clinical pathology.

Adsorption of factor VIII antigen-activity complex by collagen.

Y. Legrand, J. Caen, F. Fauvel, 1978, Thrombosis research.

Platelet adhesion to type I collagen and alpha 1 (I)3 trimers: involvement of the C-terminal alpha 1 (I) CB6A peptide.

Y. Legrand, J. Caen, F. Fauvel, 1978, Thrombosis research.

Two simple methods for the quantitative evaluation of platelet adhesion to collagen.

M. Lebret, Y. Legrand, J. Caen, 1976, Pathologie-biologie.

Inhibition of platelet collagen interactions by the C1s subcomponent of the first component of complement

J. Wautier, Y. Legrand, J. Caen, 1981 .

Recent data on thrombasthenia.

J. Caen, 2009, Acta medica Scandinavica. Supplementum.

Granulocytic sarcoma of the small intestine: a case report.

J. Caen, C. Cywiner-Golenzer, M. Grange, 1988, Nouvelle revue francaise d'hematologie.

Reassessment of protein tyrosine phosphorylation in thrombasthenic platelets: evidence that phosphorylation of cortactin and a 64-kD protein is dependent on thrombin activation and integrin alphaIIb beta3.

J. Rosa, J. Maclouf, F. Grelac, 1997, Blood.

Association of autoimmune thrombocytopenic purpura (AITP), Graves' disease and ovarian carcinoma.

C. Dosquet, S. Bellucci, J. Caen, 1991, Nouvelle revue francaise d'hematologie.

Specific determination and identification of cross-linked fibrin degradation products in patients under thrombolytic therapy for myocardial infarction.

J. Soria, C. Soria, M. Samama, 1987, Seminars in thrombosis and hemostasis.

[Fibrinogen, a vascular risk factor].

J. Soria, C. Soria, J. Collet, 1993, Bulletin de l'Academie nationale de medecine.

Probing Conformational Changes in the I-like Domain and the Cysteine-rich Repeat of Human β3 Integrins following Disulfide Bond Disruption by Cysteine Mutations

N. Kieffer, N. Brons, J. Caen, 2001, The Journal of Biological Chemistry.

Enhanced expression of urokinase activity on U 937 cell line by 1,25-dihydroxyvitamin D3 induction.

J. Soria, C. Soria, C. Dosquet-Bernard, 1988, Thrombosis research. Supplement.

In vivo effect of ticlopidine on fibrinogen-platelet cofactor activity and binding of fibrinogen to platelets.

J. Soria, C. Soria, J. Caen, 1984, Agents and actions. Supplements.

Indapamide Inhibits Human Platelet Aggregation in vitro: Comparison with Hydrochlorothiazide

D. Mollé, F. Rendu, J. Caen, 1993, Journal of cardiovascular pharmacology.

[Effects of acetylsalicylic acid in hemorrhagic diseases].

J. Beaumont, J. Caen, J. Bernard, 1956, Le Sang.

Complement (C6) and platelet activation by thrombin in humans.

J. Wautier, J. Caen, A. Peltier, 1979, Thrombosis Research.

Evidence for C1 on human platelets.

J. Wautier, G. Tobelem, J. Caen, 1973, Haemostasis.

[Utilization of P.P.B. in congenital deficiencies of a factor of the prothrombin complex (Stuart factor deficiency, true hypoconvertinemia)].

J. Caen, M. Larrieu, J. Bernard, 1959, Pathologie et biologie.

Analogy between fibrinogen and casein. Effect of an undecapeptide isolated from kappa-casein on platelet function.

C. Soria, P. Jollès, A. Fiat, 1986, European journal of biochemistry.

Some Considerations about the Purification and Standardization of Collagen from Patients with Prolonged Bleeding Time

Y. Legrand, J. Caen, 1975, Thrombosis and Haemostasis.

KRDS, a new peptide derived from human lactotransferrin, inhibits platelet aggregation and release reaction.

P. Jollès, A. Fiat, F. Rendu, 1990, European journal of biochemistry.

Platelet acquired defect in PDGF and β thromboglobulin content in hairy cell leukaemia: improvement after interferon therapy

F. Sigaux, G. Flandrin, L. Degos, 1987, British journal of haematology.

Platelet interaction with polymerizing fibrin in Glanzmann's thrombasthenia.

J. Caen, S. Niewiarowski, S. Levy‐toledano, 1981, Thrombosis research.

Biologically active peptides of casein and lactotransferrin implicated in platelet function

P. Jollès, A. Fiat, J. Caen, 1989, Journal of Dairy Research.

Carboxyterminal peptides with the dimeric form of PF4 retain the inhibitory effect on the growth of human megakaryoblastic cell lines.

J. Amiral, Z. Han, J. Caen, 1996, The Journal of laboratory and clinical medicine.

Negative regulation of human megakaryocytopoiesis by human platelet factor 4 (PF4) and connective tissue-activating peptide (CTAP-III).

M. Baggiolini, A. Walz, Z. Han, 1990, International journal of cell cloning.

Platelet fibrinogen

J. Caen, P. Castaldi, 1965, Journal of clinical pathology.

Platelet-associated fibrinogen: Conformational change of fibrinogen induced by its adsorption to platelet-surface

J. Soria, C. Soria, A. Bernadou, 1986 .

New insights into the regulation of megakaryocytopoiesis by haematopoietic and fibroblastic growth factors and transforming growth factor beta 1.

Z. Han, S. Bellucci, J. Caen, 1992, British journal of haematology.

[Epsilon aminocaproic acid and hematurias in hemophiliacs. 3 cases of transient unilateral renal obstruction].

Y. Sultan, D. Meyer, J. Caen, 1966, Bibliotheca haematologica.

Separation of human blood platelet elastase and proelastase by affinity chromatography.

L. Robert, Y. Legrand, J. Caen, 1975, Biochemical and Biophysical Research Communications - BBRC.

Purification of platelet proteases: Activation of proelastase by a trypsin‐like enzyme

Y. Legrand, J. Caen, G. Pignaud, 1977, FEBS letters.

[Norgestrienone, a possible therapeutic agent in hereditary angioneurotic edema].

J. Wautier, J. Caen, 1986, Presse medicale.

patients with the gray platelet syndrome Specific protein and glycoprotein deficiencies in platelets isolated from two

C. Soria, A. Nurden, T. Kunicki, 2011 .

Substrate Specificity of Leukocyte and Platelet Elastases

Y. Legrand, J. Caen, L. Robert, 1978, Thrombosis and Haemostasis.

Comparison of von Willebrand Disease and Bernard-Soulier Syndrome

Y. Sultan, A. Nurden, G. Tobelem, 1977, Thrombosis and Haemostasis.

Platelet Elastase and Leukocyte Elastase are two Different Entities

J. Wautier, Y. Legrand, J. Caen, 1977, Thrombosis and Haemostasis.

Human blood platelet elastase and proelastase. Activation of proelastase and release of elastase after ahesion of platelets to collagen.

Y. Legrand, J. Caen, G. Pignaud, 1977, Haemostasis.

[Platelet factor 4 acts as both inhibitor and protector of hematopoietic precursor cells: possible mechanism of action].

X. Wang, X. Zhang, Z. Han, 1995, Shi yan sheng wu xue bao.

A Ser752→Pro substitution in the cytoplasmic domain of β3 in a Glanzmann thrombasthenia variant fails to prevent interactions between the αIIbβ3 integrin and the platelet granule pool of fibrinogen

P. Nurden, A. Nurden, J. Caen, 2002 .

A 13-24 C-terminal peptide related to PF4 accelerates hematopoietic recovery of progenitor cells in vivo in mice treated with 5-fluorouracil.

J. Amiral, Z. Han, J. Caen, 1997, International journal of hematology.

Release of Elastolytic Activity from Blood Platelets

L. Robert, Y. Legrand, J. Caen, 1970, Nature.

Thrombocytopenia with thrombocytopathy possibly related to abnormalities of intracellular Ca++ fluxes and followed by the development of leukaemia.

J. Maclouf, F. Rendu, G. Tobelem, 2009, Scandinavian journal of haematology.

[Platelets and aging].

S. Bellucci, J. Caen, 1992, Comptes rendus des seances de la Societe de biologie et de ses filiales.

Influence of lithium on aggregation, release-reaction and function of human platelets.

C. Haanen, J. Caen, H. Wessels, 1972, Pathologie-biologie.

Abnormal cAMP‐induced phosphorylation of rap 1, protein in grey platelet syndrome platelets

F. Wuytack, J. Caen, E. Corvazier, 1994, British journal of haematology.

Dual structural requirements for multilineage hematopoietic-suppressive activity of chemokine-derived peptides.

M. Delepierre, M. Rholam, P. Cohen, 2000, Biochemistry.

γ M Globulin and Thrombasthenie Platelets

J. Caen, S. Cronberg, D. Hurez, 1970, Thrombosis and Haemostasis.

[FUNCTIONAL RELATION BETWEEN ERYTHROPLASTIN (ERYTHROCYTE COAGULANT FACTOR) AND PLASMA FACTORS: PROACCELERIN (V), PROCONVERTIN (VII) AND STUART FACTOR(X)].

J. Caen, H. Gaertner, 1964, Acta physiologica Polonica.

[Erythroplastin: coagulant factor of the erythrocytes. Relation to proaccelerin, proconvertin and the Stuart factor].

J. Caen, H. Gaertner, 1961, Pathologie et biologie.

[Expression of cyclin B in megakaryocytes and cells of other hematopoietic lines].

L. Li, D. Tenza, Z. Han, 1993, Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie.

Prelining of polytetrafluoroethylene grafts with cultured human endothelial cells isolated from varicose veins.

A. Bikfalvi, G. Tobelem, E. Dupuy, 1989, Surgery.

[Endothelial cells and adhesion of red cells in diabetes and sickle cell anemia. Quantitative and qualitative aspects].

F. Galactéros, J. Wautier, P. Passa, 1984, Nouvelle revue francaise d'hematologie.

Vincristine-induced thrombocytosis in the rat. Thrombopoiesis and platelet populations.

C. Legrand, J. Caen, A. Eberlin, 1973, Pathologie et biologie.

Impaired Prothrombin Consumption in Bernard-Soulier Syndrome Is Corrected In Vitro by Human Factor VIII

D. Meyer, J. Girma, S. Bellucci, 1997, Thrombosis and Haemostasis.

Defective adhesion of blood platelets to vascular microfibrils in the Bernard-Soulier syndrome.

F. Fauvel-Lafève, Y. Legrand, J. Caen, 1993, Blood.

Platelets : physiology and pathology

P. Kubisz, J. Caen, S. Cronberg, 1977 .

Diffuse Severe Digestive Angiodysplasia in Bernard-Soulier Syndrome

L. Drouet, P. Bitoun, G. Tobelem, 1995, Thrombosis and Haemostasis.

PDGF modifies phosphoinositide metabolism and inhibits aggregation and release in human platelets.

M. Bryckaert, F. Rendu, G. Tobelem, 1986, Biochemical and biophysical research communications.

Are megakaryocytes and endothelial cells sisters?

Z. Han, J. Caen, 1993, The Journal of laboratory and clinical medicine.

Cytokines acting on committed haematopoietic progenitors.

Z. Han, J. Caen, 1994, Bailliere's clinical haematology.

PHARMACOLOGICAL STUDIES OF PLATELET ANTIAGGREGANTS USING AN IN VITRO MODEL OF PRIMARY HEMOSTASIS.

S. Bellucci, J. Caen, E. Cambau, 1987, Thrombosis and Haemostasis.

A Glanzmann thrombasthenia family associated with a TUBB1‐related macrothrombocytopenia

P. Nurden, B. Guillet, X. Pillois, 2019, Journal of thrombosis and haemostasis : JTH.

Release reaction in washed platelet suspensions induced by kaolin and other particles.

J. Caen, S. Cronberg, 2009, Scandinavian journal of haematology.

Elastolytic protease in blood platelets.

Y. Legrand, J. Caen, G. Pignaud, 1971, Series haematologica.

The antithrombotic effect of KRDS, a lactotransferrin peptide, compared with RGDS.

A. Fiat, L. Drouet, C. Bal dit Sollier, 1990, Nouvelle revue francaise d'hematologie.