Sandrine Desrayaud

Brain region-specific enhancement of remyelination and prevention of demyelination by the CSF1R kinase inhibitor BLZ945

Wilfried Frieauff, E. Giorgetti, N. Accart, 2018, Acta Neuropathologica Communications.

Discovery of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors: structure-based design and in vivo reduction of amyloid β-peptides.

Jean-Michel Rondeau, Laura Jacobson, M. Staufenbiel, 2012, Journal of medicinal chemistry.

Macrocyclic peptidomimetic beta-secretase (BACE-1) inhibitors with activity in vivo.

Jean-Michel Rondeau, Marina Tintelnot-Blomley, M. Staufenbiel, 2009, Bioorganic & medicinal chemistry letters.

Structure based design, synthesis and SAR of cyclic hydroxyethylamine (HEA) BACE-1 inhibitors.

Clive McCarthy, Jean-Michel Rondeau, Marina Tintelnot-Blomley, 2011, Bioorganic & medicinal chemistry letters.

Design and Development of a Cyclic Decapeptide Scaffold with Suitable Properties for Bioavailability and Oral Exposure

Hans-Jörg Roth, Marianne Fouché, Markus Blatter, 2016, ChemMedChem.

Benzimidazoles as Potent and Orally Active mGlu5 Receptor Antagonists with an Improved PK Profile.

M. Fendt, I. Vranesic, S. Desrayaud, 2011, ACS medicinal chemistry letters.