J. Khillan

发表

Requirement of the RNA editing deaminase ADAR1 gene for embryonic erythropoiesis.

K. Nishikura, P. Gadue, Qingde Wang, 2000, Science.

Genome Editing in Mice Using CRISPR/Cas9 Technology

B. Hall, J. Khillan, A. Cho, 2018, Current protocols in cell biology.

Tissue-specific and developmentally regulated expression of human elastin promoter activity in transgenic mice.

J. Rosenbloom, J. Uitto, J. Khillan, 1994, The Journal of biological chemistry.

Vitamin A/Retinol and Maintenance of Pluripotency of Stem Cells

J. Khillan, 2014, Nutrients.

Cryopreservation Protocols for Genetically Engineered Mice

A. Kulkarni, J. Khillan, Kyoungin Cho, 2021, Current protocols.

Restoration of normal bone development by human homologue of collagen type II (COL2A1) gene in Col2a1 null mice

R. Tuan, P. U. Rani, E. Stringa, 1999, Developmental dynamics : an official publication of the American Association of Anatomists.

Defects in lens fiber differentiation are linked to c-mos overexpression in transgenic mice.

G. V. Vande Woude, H. Westphal, J. Khillan, 1987, Genes & development.

Crystallin genes: lens specificity of the murine alpha A-crystallin gene.

J. Piatigorsky, P. Overbeek, H. Westphal, 1987, Environmental health perspectives.

Specificity of Gene Expression and Insertional Mutagenesis in Transgenic Mice

J. Piatigorsky, P. Overbeek, H. Westphal, 1987 .

Lens-specific expression and developmental regulation of the bacterial chloramphenicol acetyltransferase gene driven by the murine alpha A-crystallin promoter in transgenic mice.

J. Piatigorsky, P. Overbeek, H. Westphal, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Phenotypic variability and incomplete penetrance of spontaneous fractures in an inbred strain of transgenic mice expressing a mutated collagen gene (COL1A1).

B. Sokolov, D. Prockop, J. Khillan, 1994, The Journal of clinical investigation.

Regulation of the alpha 1(I) collagen promoter in vascular smooth muscle cells. Comparison with other alpha 1(I) collagen-producing cells in transgenic animals and cultured cells.

B. Sokolov, D. Breault, B. Kream, 1994, The Journal of biological chemistry.

The human immunodeficiency virus long terminal repeat is preferentially expressed in Langerhans cells in transgenic mice.

H. Gendelman, J. Leonard, M. Martin, 1989, AIDS research and human retroviruses.

Apoptosis of chondrocytes in transgenic mice lacking collagen II.

H. Helminen, D. Prockop, S. W. Li, 1997, Experimental cell research.

Oncogenesis of the lens in transgenic mice.

J. Piatigorsky, P. Overbeek, H. Westphal, 1987, Science.

Mutations in Type 1 Procollagen That Cause Osteogenesis Imperfecta: Effects of the Mutations on the Assembly of Collagen into Fibrils, the Basis of Phenotypic Variations, and Potential Antisense Therapies

H. Helminen, D. Prockop, A. Colige, 1993, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Suppression of liver regeneration and hepatocyte proliferation in hepatocyte‐targeted glypican 3 transgenic mice

A. Bell, G. Michalopoulos, Jian-Hua Luo, 2010, Hepatology.

Gata3 ZsG and Gata3 ZsG-fl: Novel murine Gata3 reporter alleles for identifying and studying Th2 cells and ILC2s in vivo

J. Kabat, Jinfang Zhu, Chengyu Liu, 2022, Frontiers in Immunology.

Expression of a partially deleted gene of human type II procollagen (COL2A1) in transgenic mice produces a chondrodysplasia.

L. Ala‐Kokko, H. Helminen, D. Prockop, 1991, Proceedings of the National Academy of Sciences of the United States of America.

An inbred line of transgenic mice expressing an internally deleted gene for type II procollagen (COL2A1). Young mice have a variable phenotype of a chondrodysplasia and older mice have osteoarthritic changes in joints.

L. Ala‐Kokko, H. Helminen, M. Tammi, 1993, The Journal of clinical investigation.

Developmental and tissue-specific expression directed by the alpha 2 type I collagen promoter in transgenic mice.

P. Overbeek, H. Westphal, J. Khillan, 1986, Proceedings of the National Academy of Sciences of the United States of America.

The complete cDNA coding sequence for the mouse proα1(I) chain of type I procollagen

D. Prockop, J. Khillan, Shi-Wu Li, 1995 .

Structural and functional analysis of Ccr1l1, a Rodentia-restricted eosinophil-selective chemokine receptor homologue

I. Hsu, P. Murphy, J. Khillan, 2021, The Journal of biological chemistry.

Transgenic mice expressing a partially deleted gene for type I procollagen (COL1A1). A breeding line with a phenotype of spontaneous fractures and decreased bone collagen and mineral.

H. Helminen, D. Prockop, E. Hume, 1993, The Journal of clinical investigation.

Stress-induced Apoptosis Associated with Null Mutation of ADAR1 RNA Editing Deaminase Gene*

M. Weiss, K. Nishikura, M. Miyakoda, 2004, Journal of Biological Chemistry.

Identification and cloning of integration site of DNA by PCR.

D. Prockop, S. W. Li, J. Khillan, 1996, BioTechniques.

Genes inducing iPS phenotype play a role in hepatocyte survival and proliferation in vitro and liver regeneration in vivo

A. Bell, G. Michalopoulos, W. Bowen, 2011, Hepatology.

Differential regulation of transcription factor T-bet induction during NK cell development and T helper-1 cell differentiation.

A. Sher, Kairong Cui, K. Zhao, 2022, Immunity.

Maintenance of feeder free anchorage independent cultures of ES and iPS cells by retinol/vitamin A

J. Khillan, Rohit Sharma, H. Bhatia, 2012, Journal of cellular biochemistry.

Neuropathological changes in transgenic mice carrying copies of a transcriptionally activated Mos protooncogene

G. V. Vande Woude, L. Cork, H. Westphal, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Amplification of tumor inducing putative cancer stem cells (CSCs) by vitamin A/retinol from mammary tumors.

Qingde Wang, J. Khillan, Rohit Sharma, 2013, Biochemical and biophysical research communications.

Accelerated liver regeneration and hepatocarcinogenesis in mice overexpressing serine‐45 mutant β‐catenin

C. Dai, Sucha Singh, S. Monga, 2010, Hepatology.

Immunopathogenesis of human immunodeficiency virus infection in the central nervous system

H. Gendelman, J. Leonard, M. Meltzer, 1988, Annals of neurology.

Suppression of ES cell differentiation by retinol (vitamin A) via the overexpression of Nanog.

J. Khillan, Minying Yang, Joyce Dawes, 2007, Differentiation; research in biological diversity.

A genome-wide screen uncovers multiple roles for mitochondrial nucleoside diphosphate kinase D in inflammasome activation

Eugen C. Buehler, I. Fraser, Sharat J. Vayttaden, 2021, Science Signaling.

A Novel Signaling by Vitamin A/Retinol Promotes Self Renewal of Mouse Embryonic Stem Cells by Activating PI3K/Akt Signaling Pathway via Insulin‐Like Growth Factor‐1 Receptor

J. Khillan, Liguo Chen, 2009, Stem cells.

Limb bud progenitor cells induce differentiation of pluripotent embryonic stem cells into chondrogenic lineage.

J. Khillan, Yaping Sui, Trena Clarke, 2003, Differentiation; research in biological diversity.

Gene transactivation mediated by the TAT gene of human immunodeficiency virus in transgenic mice.

H. Westphal, M. Rosenberg, R. Sweet, 1988, Nucleic acids research.

Dermis resident macrophages orchestrate localized ILC2-eosinophil circuitries to maintain their M2-like properties and promote non-healing cutaneous leishmaniasis

J. Kabat, O. Kamenyeva, B. Kelsall, 2023, Research square.

Promotion of Feeder‐Independent Self‐Renewal of Embryonic Stem Cells by Retinol (Vitamin A)

J. Khillan, Liguo Chen, 2008, Stem cells.

Feeder-independent culture of mouse embryonic stem cells using vitamin A/retinol.

J. Khillan, Liguo Chen, 2010, Methods in molecular biology.

Preparation of animals with a high degree of chimerism by one-step coculture of embryonic stem cells and preimplantation embryos.

J. Khillan, Y. Bao, 1997, BioTechniques.

A Simple and Convenient Method for Preparing Chimeric Animals from Embryonic stem (ES) Cells

J. Khillan, P. U. Rani, 2003, Transgenic Research.

Tissue-specific Expression of the Gene for Type I Procollagen (COL1A1) in Transgenic Mice

B. Sokolov, D. Prockop, J. Khillan, 1995, The Journal of Biological Chemistry.

Transgenic animals as bioreactors for expression of recombinant proteins.

J. Khillan, 1997, Methods in molecular biology.

Multiple ovarian transplants to rescue a transgenic line of mice

G. Michalopoulos, W. Mars, Bowen Liu, 2010, Lab Animal.

Partial rescue of a lethal phenotype of fragile bones in transgenic mice with a chimeric antisense gene directed against a mutated collagen gene.

D. Prockop, S. W. Li, J. Khillan, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Generation of chondrocytes from embryonic stem cells.

J. Khillan, 2006, Methods in molecular biology.

An ultrastructural, microanalytical, and spectroscopic study of bone from a transgenic mouse with a COL1.A1 pro-alpha-1 mutation.

D. Prockop, J. Cassella, J. Khillan, 1994, Bone.

Transgenic Mice Expressing a Partially

H. Helminen, D. Prockop, E. Hume, 2013 .

Transgenic mice that express a mini-gene version of the human gene for type I procollagen (COL1A1) develop a phenotype resembling a lethal form of osteogenesis imperfecta.

A. Olsen, D. Prockop, S. Kontusaari, 1991, Journal of Biological Chemistry.

Transgenic mice with inactivation of the COL11A2 gene demonstrate a minimal cartilage phenotype at birth and at 7 months

D. Prockop, R. Mayne, J. Khillan, 1996 .

Promoter sequences of murine alpha A crystallin, murine alpha 2(I) collagen or of avian sarcoma virus genes linked to the bacterial chloramphenicol acetyl transferase gene direct tissue-specific patterns of chloramphenicol acetyl transferase expression in transgenic mice.

J. Piatigorsky, P. Overbeek, K. Bernstein, 1985, Cold Spring Harbor symposia on quantitative biology.

Ovarian transplant for transgenic rescue

J. Khillan, 2010, Lab Animal.

Anthrax lethal factor cleaves regulatory subunits of phosphoinositide-3 kinase to contribute to toxin lethality

S. Leppla, M. Moayeri, T. Bugge, 2020, Nature Microbiology.

Genotyping Protocols for Genetically Engineered Mice

B. Hall, J. Khillan, A. Limaye, 2023, Current protocols.