Chang X. Zhang

发表

Genetic ablation of the tumor suppressor menin causes lethality at mid-gestation with defects in multiple organs

A. Aguzzi, Zhao-Qi Wang, I. Radovanovic, 2003, Mechanisms of Development.

Comparison of nonsense-mediated mRNA decay efficiency in various murine tissues

Olga Anczuków, S. Mazoyer, M. Buisson, 2008, BMC Genetics.

Deletion of Menin in craniofacial osteogenic cells in mice elicits development of mandibular ossifying fibroma

P. Liu, Sooyeon Lee, J. Tuckermann, 2018, Oncogene.

Generation of a conditional mouse model to target Acvr1b disruption in adult tissues

R. Pommier, L. Bartholin, P. Bertolino, 2013, Genesis.

Chemoprevention with Enalapril and Aspirin in Men1(+/T) Knockout Mouse Model

V. Fendrich, D. Bartsch, B. Joos, 2018, Neuroendocrinology.

Loss of menin in osteoblast lineage affects osteocyte–osteoclast crosstalk causing osteoporosis

J. David, Sooyeon Lee, M. Zaiss, 2017, Cell Death and Differentiation.

Transdifferentiation of pancreatic α-cells into insulin-secreting cells: From experimental models to underlying mechanisms.

Jieli Lu, P. Bertolino, Chang X. Zhang, 2014, World journal of diabetes.

Expression and chromosomal localization of the Requiem gene

C. Larsson, B. Teh, N. Copeland, 1998, Mammalian Genome.

Islet Cells Serve as Cells of Origin of Pancreatic Gastrin-Positive Endocrine Tumors

J. Rehfeld, F. Pattou, V. Hervieu, 2015, Molecular and Cellular Biology.

Heterozygous Men1 mutant mice develop a range of endocrine tumors mimicking multiple endocrine neoplasia type 1.

Zhao-Qi Wang, W. Tong, D. Galendo, 2003, Molecular endocrinology.

Alpha cell-specific Men1 ablation triggers the transdifferentiation of glucagon-expressing cells and insulinoma development.

P. Herrera, Jieli Lu, A. Calender, 2010, Gastroenterology.

Menin directs regionalized decidual transformation through epigenetically setting PTX3 as an obstacle balancing FGF and BMP signaling

Zhong-xian Lu, Haili Bao, Haibin Wang, 2021 .

Deregulation of anti-Mullerian hormone/BMP and transforming growth factor-beta pathways in Leydig cell lesions developed in male heterozygous multiple endocrine neoplasia type 1 mutant mice.

Jieli Lu, A. Calender, N. Hussein, 2008, Endocrine-related cancer.

Tumour suppressor menin is essential for development of the pancreatic endocrine cells.

R. Scharfmann, Zhao-Qi Wang, B. Duvillié, 2008, The Journal of endocrinology.

The scaffold protein menin is essential for activating the MYC locus and MYC‐mediated androgen receptor transcription in androgen receptor‐dependent prostate cancer cells

V. Vlaeminck-Guillem, M. Le Romancer, P. Bertolino, 2021, Cancer communications.

Foxa2, a novel protein partner of the tumour suppressor menin, is deregulated in mouse and human MEN1 glucagonomas

F. Pattou, Rui Du, E. Leteurtre, 2017, The Journal of pathology.

novel protein partner of tumour suppressor menin , is deregulated in mouse and human MEN 1 glucagonomas Deregulation of Foxa 2 in menin-deficient pancreatic α-cells

F. Pattou, Rui Du, E. Leteurtre, 2017 .

Reconstituted expression of menin in Men1-deficient mouse Leydig tumour cells induces cell cycle arrest and apoptosis.

N. Hussein, A. Morera, M. Asensio, 2007, European journal of cancer.

Both PAX4 and MAFA Are Expressed in a Substantial Proportion of Normal Human Pancreatic Alpha Cells and Deregulated in Patients with Type 2 Diabetes

F. Pattou, E. Leteurtre, J. Kerr-Conte, 2013, PloS one.

Generation and characterization of Men1 mutant mouse models for studying MEN1 disease

Chang X. Zhang, Yakun Luo, R. A. Ziki, 2019, Journal of Pancreatology.

Characterisation of prostate cancer lesions in heterozygous Men1 mutant mice

Zhao-Qi Wang, Jieli Lu, L. Frappart, 2010, BMC Cancer.

Men1 disruption in Nkx3.1-deficient mice results in ARlow/CD44+ microinvasive carcinoma development with the dysregulated AR pathway

V. Firlej, F. Vacherot, V. Vlaeminck-Guillem, 2020, Oncogene.

Expression analysis of endogenous menin, the product of the multiple endocrine neoplasia type 1 gene, in cell lines and human tissues

G. Lenoir, A. Calender, L. Frappart, 2000, International journal of cancer.

Analysis of p27Kip1 Expression in Insulinomas Developed in Pancreatic β-cell Specific Men1 Mutant Mice

P. Bertolino, H. Casse, Chang X. Zhang, 2005, Familial Cancer.

Reduction of Menin Expression Enhances Cell Proliferation and Is Tumorigenic in Intestinal Epithelial Cells*

J. Chayvialle, A. Calender, Chang X. Zhang, 2004, Journal of Biological Chemistry.

Exploring the MEN1 dependent modulation of caspase 8 and caspase 3 in human pancreatic and murine embryo fibroblast cells

M. Buchholz, P. Di Fazio, P. Bertolino, 2021, Apoptosis.

Functional characterization of a promoter region in the human MEN1 tumor suppressor gene.

C. Vercherat, M. Fromaget, J. Chayvialle, 2003, Journal of molecular biology.

Pancreatic beta-cell-specific ablation of the multiple endocrine neoplasia type 1 (MEN1) gene causes full penetrance of insulinoma development in mice.

Zhao-Qi Wang, P. Herrera, W. Tong, 2003, Cancer research.

Pancreatic-Cell-specific Ablation of the Multiple Endocrine Neoplasia Type 1 ( MEN 1 ) Gene Causes Full Penetrance of Insulinoma Development in Mice 1

Zhao-Qi Wang, P. Herrera, W. Tong, 2003 .

Reduced menin expression leads to decreased ERα expression and is correlated with the occurrence of human luminal B-like and ER-negative breast cancer subtypes

I. Treilleux, T. Bachelot, L. Corbo, 2021, Breast Cancer Research and Treatment.

Menin regulates Inhbb expression through an Akt/Ezh2-mediated H3K27 histone modification.

M. Chanal, A. Hennino, P. Bertolino, 2017, Biochimica et biophysica acta. Gene regulatory mechanisms.

ActivinB Is Induced in Insulinoma To Promote Tumor Plasticity through a β-Cell-Induced Dedifferentiation

O. Andersson, O. Ritvos, A. Hennino, 2015, Molecular and Cellular Biology.

MEN1 silencing aggravates tumorigenic potential of AR-independent prostate cancer cells through nuclear translocation and activation of JunD and β-catenin

S. Baron, V. Vlaeminck-Guillem, M. Le Romancer, 2021, Journal of experimental & clinical cancer research : CR.

Expressions of Livin and IGF-II in colorectal carcinoma and their relationship

Chang X. Zhang, Ge Wang, Guanming Bao, 2010 .

Alpha cell-specific Men1 ablation triggers the transdifferentiation of glucagon-expressing cells and insulinoma development.

P. Herrera, Jieli Lu, A. Calender, 2010, Gastroenterology.