Todd J. Sullivan

发表

Targeting Fatty Acid Biosynthesis for the Development of Novel Chemotherapeutics against Mycobacterium tuberculosis: Evaluation of A-Ring-Modified Diphenyl Ethers as High-Affinity InhA Inhibitors

Peter J. Tonge, Richard A. Slayden, P. Tonge, 2007, Antimicrobial Agents and Chemotherapy.

Virtual screening reveals allosteric inhibitors of the Toxoplasma gondii thymidylate synthase-dihydrofolate reductase.

William L. Jorgensen, Markus K. Dahlgren, Karen S. Anderson, 2014, Bioorganic & medicinal chemistry letters.

Synthesis and in vitro antimycobacterial activity of B-ring modified diaryl ether InhA inhibitors.

Peter J Tonge, P. Tonge, F. Johnson, 2008, Bioorganic & medicinal chemistry letters.

Inhibition of the bacterial enoyl reductase FabI by triclosan: a structure-reactivity analysis of FabI inhibition by triclosan analogues.

P. Tonge, C. Simmerling, F. Johnson, 2004, Journal of medicinal chemistry.

[d4U]-spacer-[HI-236] double-drug inhibitors of HIV-1 reverse-transcriptase.

Christopher M. Bailey, K. Anderson, Todd J. Sullivan, 2010, Bioorganic & medicinal chemistry.

Design, Synthesis, and Antiviral Evaluation of Chimeric Inhibitors of HIV Reverse Transcriptase.

K. Anderson, M. Chordia, K. Frey, 2013, ACS medicinal chemistry letters.

Bifunctional inhibition of human immunodeficiency virus type 1 reverse transcriptase: mechanism and proof-of-concept as a novel therapeutic design strategy.

Christopher M. Bailey, W. L. Jorgensen, K. Anderson, 2013, Journal of medicinal chemistry.

Mechanism and inhibition of saFabI, the enoyl reductase from Staphylococcus aureus.

Christopher F Stratton, T. Kirikae, P. Tonge, 2008, Biochemistry.

Substituted diphenyl ethers as a broad-spectrum platform for the development of chemotherapeutics for the treatment of tularaemia.

Peter J Tonge, P. Tonge, R. Slayden, 2009, The Journal of antimicrobial chemotherapy.

High affinity InhA inhibitors with activity against drug-resistant strains of Mycobacterium tuberculosis.

Peter J Tonge, Christopher F Stratton, P. Tonge, 2006, ACS chemical biology.

Synthesis and in vitro antimycobacterial activity of B-ring modified diaryl ether InhA inhibitors.

P. Tonge, F. Johnson, R. Slayden, 2008, Bioorganic & medicinal chemistry letters.