Stefan Christian Metzler

URI is an oncogene amplified in ovarian cancer cells and is required for their survival.

Wilhelm Krek, Holger Moch, Alex Soltermann, 2011, Cancer cell.

S6K1-mediated disassembly of mitochondrial URI/PP1gamma complexes activates a negative feedback program that counters S6K1 survival signaling.

R. Aebersold, M. Gstaiger, A. Schmidt, 2007, Molecular cell.