Alexander P Hynes

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Widespread anti-CRISPR proteins in virulent bacteriophages inhibit a range of Cas9 proteins

Philippe Horvath, Sylvain Moineau, Christian Cambillau, 2018, Nature Communications.

Temperate phage-antibiotic synergy across antibiotic classes reveals new mechanism for preventing lysogeny

Alexander P Hynes, Rabia Fatima, A. M. Al-Anany, 2024, mBio.

CRISPR-Cas Systems: Making the Cut: Unlike restriction-modification systems, CRISPR-Cas systems readily acquire new specificities to confer adaptive immune-like responses

S. Moineau, Alexander P Hynes, 2014 .

DNA packaging bias and differential expression of gene transfer agent genes within a population during production and release of the Rhodobacter capsulatus gene transfer agent, RcGTA

A. Lang, Alexander P Hynes, R. Mercer, 2012, Molecular microbiology.

Anti-CRISPR AcrIIa6 cubic form

Y. Doyon, C. Cambillau, P. Horvath, 2018 .

Widespread anti-CRISPR proteins in virulent bacteriophages inhibit a range of Cas9 proteins

Y. Doyon, C. Cambillau, P. Horvath, 2018, Nature Communications.

Temperate phage-antibiotic synergy eradicates bacteria through depletion of lysogens.

Alexander P Hynes, Rabia Fatima, A. M. Al-Anany, 2021, Cell reports.

An anti-CRISPR from a virulent streptococcal phage inhibits Streptococcus pyogenes Cas9

Philippe Horvath, Alexander P. Hynes, Sylvain Moineau, 2017, Nature Microbiology.

Detecting natural adaptation of the Streptococcus thermophilus CRISPR-Cas systems in research and classroom settings

H. Deveau, S. Moineau, D. Tremblay, 2017, Nature Protocols.

Programming Native CRISPR Arrays for the Generation of Targeted Immunity

Alexander P. Hynes, Simon J. Labrie, Sylvain Moineau, 2016, mBio.

Adaptation in bacterial CRISPR-Cas immunity can be driven by defective phages

S. Moineau, M. Villion, Alexander P Hynes, 2014, Nature Communications.

Applications of CRISPR-Cas in its natural habitat.

S. Moineau, Alexander P Hynes, Marie-Laurence Lemay, 2016, Current opinion in chemical biology.

Bacterial membrane vesicles and phages in blood after consumption of lacticaseibacillus rhamnosus JB-1

J. Bienenstock, M. F. Mian, Alexander P Hynes, 2021, Gut microbes.

Efficacy of Salmonella Bacteriophage S1 Delivered and Released by Alginate Beads in a Chicken Model of Infection

Alexander P Hynes, Susana E Mendoza-Elvira, E. Hernández-Baltazar, 2021, Viruses.

Characterization of a newly discovered Mu-like bacteriophage, RcapMu, in Rhodobacter capsulatus strain SB1003.

J. Beatty, A. Lang, P. Fogg, 2011, Virology.

Functional and Evolutionary Characterization of a Gene Transfer Agent’s Multilocus “Genome”

M. Shakya, O. Zhaxybayeva, A. Lang, 2016, Molecular biology and evolution.

Phagebook: The Social Network.

S. Moineau, Alexander P Hynes, 2017, Molecular cell.

Common Oral Medications Lead to Prophage Induction in Bacterial Isolates from the Human Gut

Alexander P Hynes, Michael Shamash, S. Sutcliffe, 2021, Viruses.

Does over a century of aerobic phage work provide a solid framework for the study of phages in the gut?

Alexander P Hynes, Hiba Shareefdeen, 2021, Anaerobe.

Metabolomic Investigation of the Bacterial Response to a Metal Challenge

Alexander P. Hynes, V. Tremaroli, H. Vogel, 2008, Applied and Environmental Microbiology.

In the Anti-CRISPR Jungle, Only the Weak Thrive?

Alexander P Hynes, F. R. Croteau, 2020, Cell host & microbe.