Roman K Thomas

发表

Mutations in BRAF and KRAS converge on activation of the mitogen-activated protein kinase pathway in lung cancer mouse models.

Levi A Garraway, Lynda Chin, Kwok-Kin Wong, 2007, Cancer research.

Blood-Based Gene Expression Signatures in Non–Small Cell Lung Cancer

Thomas Zander, Andrea Hofmann, Joachim L Schultze, 2011, Clinical Cancer Research.

Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions.

Laura Tolosi, Michael Peyton, Thomas Zander, 2009, The Journal of clinical investigation.

Targeting Drug Resistance in EGFR with Covalent Inhibitors: A Structure-Based Design Approach.

Jochen Heil, Franziska Hoffgaard, Julian Engel, 2015, Journal of medicinal chemistry.

Sensitive mutation detection in heterogeneous cancer specimens by massively parallel picoliter reactor sequencing

Thomas LaFramboise, Levi A Garraway, Kwok-Kin Wong, 2006, Nature Medicine.

Genomic and Functional Fidelity of Small Cell Lung Cancer Patient-Derived Xenografts.

Mehmet Toner, Martin Peifer, Mari Mino-Kenudson, 2018, Cancer discovery.

Integrative genomic profiling of large-cell neuroendocrine carcinomas reveals distinct subtypes of high-grade neuroendocrine lung tumors

Martin Vingron, Thomas Zander, Yupeng Cun, 2018, Nature Communications.

The tumour suppressor CYLD regulates the p53 DNA damage response

Reinhard Büttner, Björn Schumacher, David Komander, 2016, Nature Communications.

Chemogenomic profiling provides insights into the limited activity of irreversible EGFR Inhibitors in tumor cells expressing the T790M EGFR resistance mutation.

Martin Peifer, Daniel Rauh, Lars Ruddigkeit, 2010, Cancer research.

Prognostic and predictive gene signature for adjuvant chemotherapy in resected non-small-cell lung cancer.

Igor Jurisica, Matthew Meyerson, Lesley Seymour, 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

A framework for identification of actionable cancer genome dependencies in small cell lung cancer

Herbert Waldmann, Takashi Ninomiya, Martin Peifer, 2012, Proceedings of the National Academy of Sciences.

Novel MEK1 mutation identified by mutational analysis of epidermal growth factor receptor signaling pathway genes in lung adenocarcinoma.

Li Ding, William Pao, Elaine R Mardis, 2008, Cancer research.

Frequent mutations in chromatin-remodeling genes in pulmonary carcinoids

Martin Vingron, Thomas Zander, Viktor Achter, 2014, Nature Communications.

Rationale for co-targeting IGF-1R and ALK in ALK fusion positive lung cancer

William Pao, Zhongming Zhao, Ronglai Shen, 2014, Nature Medicine.