J. McAllister

发表

Heirarchical clustering and beyond in PCOS endometrium: brave new world.

R. Legro, J. McAllister, 2009, The Journal of clinical endocrinology and metabolism.

The Cebpd (C/EBPδ) Gene Is Induced by Luteinizing Hormones in Ovarian Theca and Interstitial Cells But Is Not Essential for Mouse Ovary Function

M. Raffeld, M. Rudelius, E. Sterneck, 2007, PloS one.

Augmented androgen production is a stable steroidogenic phenotype of propagated theca cells from polycystic ovaries.

R. Legro, J. Strauss, J. McAllister, 1999, Molecular endocrinology.

The Journal of Clinical Endocrinology & Metabolism Printed in U.S.A. Copyright © 2000 by The Endocrine Society Differential Activity of the Cytochrome P450 17�- Hydroxylase and Steroidogenic Acute Regulatory Protein Gene Promoters in Normal and Polycystic

P. G. Quinn, R. Legro, J. Strauss, 2022 .

Valproate potentiates androgen biosynthesis in human ovarian theca cells.

J. Wood, R. Legro, J. Strauss, 2004, Endocrinology.

use and metabolic side effects expression: clues to the association between valproate Valproate-induced alterations in human theca cell gene

Jeffrey T. Chang, S. Jeffrey, R. Soldi, 2015 .

Valproate-induced alterations in human theca cell gene expression: clues to the association between valproate use and metabolic side effects.

Jerome F Strauss, J. Wood, J. Strauss, 2005, Physiological genomics.

Mesenchymal stem cell therapy ameliorates metabolic dysfunction and restores fertility in a PCOS mouse model through interleukin-10

A. Al-Hendy, A. El Andaloussi, N. Ismail, 2021, Stem cell research & therapy.

Mesenchymal stem cell therapy ameliorates metabolic dysfunction and restores fertility in a PCOS mouse model through interleukin-10

A. Al-Hendy, A. El Andaloussi, N. Ismail, 2021, Stem Cell Research & Therapy.

Increased cytochrome P450 17alpha-hydroxylase promoter function in theca cells isolated from patients with polycystic ovary syndrome involves nuclear factor-1.

P. G. Quinn, J. McAllister, J. Wickenheisser, 2004, Molecular endocrinology.

Insulin and insulin-like growth factor-I and -II modulate human granulosa-lutein cell steroidogenesis: enhancement of steroidogenic acute regulatory protein (StAR) expression.

A. Makrigiannakis, J. Strauss, L. Christenson, 1999, Molecular human reproduction.

The PCOS GWAS Candidate Gene ZNF217 Influences Theca Cell Expression of DENND1A.V2, CYP17A1, and Androgen Production

J. Strauss, J. McAllister, Jordan Newell, 2022, Journal of the Endocrine Society.

Loci on chromosome 12q13.2 encompassing ERBB3, PA2G4 and RAB5B are associated with polycystic ovary syndrome

J. Strauss, T. York, J. McAllister, 2022, medRxiv.

Human DENND1A.V2 Drives Cyp17a1 Expression and Androgen Production in Mouse Ovaries and Adrenals

M. Subler, J. Windle, J. Strauss, 2020, International journal of molecular sciences.

The Genetics of Polycystic Ovary Syndrome: From Genome-Wide Association to Molecular Mechanisms

J. Strauss, B. Modi, J. McAllister, 2018 .

Dysregulation of cytochrome P450 17alpha-hydroxylase messenger ribonucleic acid stability in theca cells isolated from women with polycystic ovary syndrome.

J. McAllister, J. Wickenheisser, Velen L. Nelson-DeGrave, 2005, The Journal of clinical endocrinology and metabolism.

Conditional response of the human steroidogenic acute regulatory protein gene promoter to sterol regulatory element binding protein-1a.

T. Osborne, J. Strauss, L. Christenson, 2001, Endocrinology.

Alterations in mitogen-activated protein kinase kinase and extracellular regulated kinase signaling in theca cells contribute to excessive androgen production in polycystic ovary syndrome.

T. Asano, M. Fujishiro, S. Kimball, 2005, Molecular endocrinology.

Alterations in MEK and ERK Signaling in Theca Cells Contribute to Excessive Androgen Production in Polycystic Ovary Syndrome (PCOS).

T. Asano, M. Fujishiro, S. Kimball, 2004 .

VCAM1 Is Induced in Ovarian Theca and Stromal Cells in a Mouse Model of Androgen Excess.

F. Stossi, J. Richards, Sheng Wu, 2019, Endocrinology.

Human ovarian theca cells in culture

J. McAllister, J. Wickenheisser, Velen L. Nelson-DeGrave, 2006, Trends in Endocrinology & Metabolism.

Human skin is a steroidogenic tissue: steroidogenic enzymes and cofactors are expressed in epidermis, normal sebocytes, and an immortalized sebocyte cell line (SEB-1).

G. Clawson, D. Thiboutot, J. McAllister, 2003, The Journal of investigative dermatology.

Alternative splicing of DENND1A, a PCOS candidate gene, generates variant 2

W. Miller, J. Strauss, M. Speek, 2016, Molecular and Cellular Endocrinology.

Decreased myo-inositol to chiro-inositol (M/C) ratios and increased M/C epimerase activity in PCOS theca cells demonstrate increased insulin sensitivity compared to controls.

J. Larner, J. McAllister, D. Heimark, 2014, Endocrine journal.

Family-based analysis of candidate genes for polycystic ovary syndrome.

Stephen C. J. Parker, E. H. Margulies, M. Urbanek, 2010, The Journal of clinical endocrinology and metabolism.

The biochemical basis for increased testosterone production in theca cells propagated from patients with polycystic ovary syndrome.

J. Wood, R. Legro, J. Strauss, 2001, The Journal of clinical endocrinology and metabolism.

Growth differentiation factor-9 inhibits 3'5'-adenosine monophosphate-stimulated steroidogenesis in human granulosa and theca cells.

J. Strauss, L. Christenson, N. Yamamoto, 2002, The Journal of clinical endocrinology and metabolism.

Loss of expression of a differentiated function gene, steroid 17 alpha-hydroxylase, as adrenocortical cells senescence in culture.

P. Hornsby, J. McAllister, R. F. Ryan, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Multiple steroidogenic factor 1 binding elements in the human steroidogenic acute regulatory protein gene 5'-flanking region are required for maximal promoter activity and cyclic AMP responsiveness.

M. Kiriakidou, T. Sugawara, J. Strauss, 1997, Biochemistry.

Expression of steroidogenic acute regulatory protein (StAR) in the human ovary.

M. Kiriakidou, T. Sugawara, J. Strauss, 1996, The Journal of clinical endocrinology and metabolism.

Stromal cells of the human postmenopausal ovary display a distinctive biochemical and molecular phenotype.

A. Dunaif, J. Strauss, L. Christenson, 2003, The Journal of clinical endocrinology and metabolism.

Defects in Ovarian Steroid Hormone Biosynthesis

J. Strauss, B. Modi, J. McAllister, 2014 .

Oxysterol Regulation of Steroidogenic Acute Regulatory Protein Gene Expression

T. Osborne, J. Strauss, L. Christenson, 1998, The Journal of Biological Chemistry.

CCAAT/Enhancer-binding Proteins Regulate Expression of the Human Steroidogenic Acute Regulatory Protein (StAR) Gene*

P. Johnson, J. Strauss, L. Christenson, 1999, The Journal of Biological Chemistry.

Steroidogenic abnormalities in ovarian theca cells in polycystic ovary syndrome

J. Strauss, J. McAllister, J. Wickenheisser, 2002 .

Functional genomics of PCOS: from GWAS to molecular mechanisms

R. Legro, J. Strauss, B. Modi, 2015, Trends in Endocrinology & Metabolism.

Cholesterol Side-Chain Cleavage Gene Expression in Theca Cells: Augmented Transcriptional Regulation and mRNA Stability in Polycystic Ovary Syndrome

Jessica M. Biegler, R. Legro, J. Strauss, 2012, PloS one.

Persistence pays off for PCOS gene prospectors.

M. Urbanek, J. Strauss, J. McAllister, 2012, The Journal of clinical endocrinology and metabolism.

The effects of growth factors and phorbol esters on steroid biosynthesis in isolated human theca interna and granulosa-lutein cells in long term culture.

E. Simpson, W. Byrd, J. McAllister, 1994, The Journal of clinical endocrinology and metabolism.

Regulation of expression of the steroidogenic acute regulatory protein (StAR) gene: A central role for steroidogenic factor 1

M. Kiriakidou, T. Sugawara, J. Holt, 1997, Steroids.

Uptake of P32-labelled cyclophosphamide from arthritic knee joints.

M. Cawley, A. Thould, J. McAllister, 1969, Annals of the rheumatic diseases.

Proliferating human granulosa-lutein cells in long term monolayer culture: expression of aromatase, cholesterol side-chain cleavage, and 3 beta-hydroxysteroid dehydrogenase.

M. Waterman, E. Simpson, J. Mason, 1990, The Journal of clinical endocrinology and metabolism.

TPA inhibits the synthesis of androgens and cortisol and enhances the synthesis non-17 alpha-hydroxylated steroids in cultured human adrenocortical cells.

P. Hornsby, J. McAllister, 1987, Endocrinology.

Culturing steroidogenic cells.

P. Hornsby, J. McAllister, 1991, Methods in enzymology.

Dual regulation of 3 beta-hydroxysteroid dehydrogenase, 17 alpha-hydroxylase, and dehydroepiandrosterone sulfotransferase by adenosine 3',5'-monophosphate and activators of protein kinase C in cultured human adrenocortical cells.

P. Hornsby, J. McAllister, 1988, Endocrinology.

MicroRNA Profiling Reveals miRNA-130b-3p Mediates DENND1A Variant 2 Expression and Androgen Biosynthesis.

K. Archer, J. Strauss, L. Christenson, 2019, Endocrinology.

Retinoids and retinol differentially regulate steroid biosynthesis in ovarian theca cells isolated from normal cycling women and women with polycystic ovary syndrome.

R. Legro, J. Strauss, J. McAllister, 2005, The Journal of clinical endocrinology and metabolism.

Overexpression of a DENND1A isoform produces a polycystic ovary syndrome theca phenotype

Bruce A. Miller, Jessica M. Biegler, R. Legro, 2014, Proceedings of the National Academy of Sciences.

Improved clonal and nonclonal growth of human, rat and bovine adrenocortical cells in culture

P. Hornsby, J. McAllister, 1987, In Vitro Cellular & Developmental Biology.

Increased transcription and increased messenger ribonucleic acid (mRNA) stability contribute to increased GATA6 mRNA abundance in polycystic ovary syndrome theca cells.

R. Spielman, K. Ewens, J. Wood, 2005, The Journal of clinical endocrinology and metabolism.

Human intraovarian interleukin-1 (IL-1) system: highly compartmentalized and hormonally dependent regulation of the genes encoding IL-1, its receptor, and its receptor antagonist.

E. Adashi, E. Katz, R. Rohan, 1992, The Journal of clinical investigation.

Hormonal regulation of androgen biosynthesis by primary cultures of testis cells from neonatal rats.

R. Meidan, A. Hsueh, J. McAllister, 1985, Endocrinology.

The homeodomain protein Pbx1 is involved in cAMP-dependent transcription of human CYP17.

M. Waterman, N. Kagawa, J. McAllister, 1997, Archives of biochemistry and biophysics.

Regulation of cholesterol side-chain cleavage and 17 alpha-hydroxylase/lyase activities in proliferating human theca interna cells in long term monolayer culture.

M. Waterman, R. Estabrook, E. Simpson, 1989, Endocrinology.

The Molecular Phenotype of Polycystic Ovary Syndrome (PCOS) Theca Cells and New Candidate PCOS Genes Defined by Microarray Analysis*

M. Urbanek, J. Wood, J. Strauss, 2003, Journal of Biological Chemistry.

Regulation of corticotropin responsiveness in human fetal adrenal cells.

W. Rainey, J. Mason, B. Carr, 1991, American journal of obstetrics and gynecology.

The molecular signature of polycystic ovary syndrome (PCOS) theca cells defined by gene expression profiling.

J. Wood, J. Strauss, J. McAllister, 2004, Journal of reproductive immunology.

Functional, long-term human theca and granulosa cell cultures from polycystic ovaries

J. McAllister, 1995, Endocrine.

PDE8A genetic variation, polycystic ovary syndrome and androgen levels in women.

R. Spielman, K. Ewens, R. Legro, 2009, Molecular human reproduction.

Ovarian Steroidogenic Abnormalities in PCOS

J. McAllister, J. Wickenheisser, 2007 .

Colocalization of Polycystic Ovary Syndrome Candidate Gene Products in Theca Cells Suggests Novel Signaling Pathways

J. Strauss, J. McAllister, M. Teves, 2019, Journal of the Endocrine Society.

Strategies to elucidate the mechanism of excessive theca cell androgen production in PCOS

J. Wood, J. Strauss, L. Christenson, 2002, Molecular and Cellular Endocrinology.

Single-Cell RNA-Seq Identifies Pathways and Genes Contributing to the Hyperandrogenemia Associated with Polycystic Ovary Syndrome

J. Strauss, J. McAllister, R. A. Harris, 2023, International journal of molecular sciences.

Functional genomics of PCOS: from GWAS to molecular mechanisms

R. Legro, J. Strauss, B. Modi, 2015, Trends in Endocrinology & Metabolism.