Keerthana Gnanapradeepan

发表

Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser

K. Wellen, R. Ahima, J. Baur, 2020, bioRxiv.

Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser

K. Wellen, R. Ahima, J. Baur, 2020, bioRxiv.

Prospective functional classification of all possible missense variants in PPARG

Inês Barroso, Ted Sharpe, Sekar Kathiresan, 2016, Nature Genetics.

PLTP is a p53 target gene with roles in cancer growth suppression and ferroptosis

N. Clarke, M. Murphy, Keerthana Gnanapradeepan, 2022, The Journal of biological chemistry.

A Novel Inhibitor of HSP70 Induces Mitochondrial Toxicity and Immune Cell Recruitment in Tumors

D. Speicher, M. Murphy, D. George, 2020, Cancer Research.

The p53 Tumor Suppressor in the Control of Metabolism and Ferroptosis

M. Murphy, Keerthana Gnanapradeepan, Subhasree Basu, 2018, Front. Endocrinol..

Mutant p53 controls tumor metabolism and metastasis by regulating PGC-1α

M. Murphy, A. Kossenkov, Keerthana Gnanapradeepan, 2018, Genes & development.

African-centric TP53 variant increases iron accumulation and bacterial pathogenesis but improves response to malaria toxin

M. Murphy, D. George, A. Kossenkov, 2020, Nature Communications.

Paradoxical Role for Wild-Type p53 in Driving Therapy Resistance in Melanoma.

Stephen M. Douglass, A. Weeraratna, M. Herlyn, 2019, Molecular cell.

African-centric TP53 variant increases iron accumulation and bacterial pathogenesis but improves response to malaria toxin

M. Murphy, D. George, A. Kossenkov, 2020, Nature Communications.