Ryan M. Peterson

发表

Biosynthetic Potential-Based Strain Prioritization for Natural Product Discovery: A Showcase for Diterpenoid-Producing Actinomycetes

Yijun Yan, Ming Ma, Ben Shen, 2014, Journal of natural products.

Development of an RNAi therapeutic for alpha-1-antitrypsin liver disease.

S. Kanner, D. Lewis, V. Subbotin, 2020, JCI insight.

Ether modifications to 1-[2-(3,4-dimethoxyphenyl)ethyl]-4-(3-phenylpropyl)piperazine (SA4503): effects on binding affinity and selectivity for sigma receptors and monoamine transporters.

J. Lever, Ryan M. Peterson, S. Z. Lever, 2015, Bioorganic & medicinal chemistry.

Engineering of Streptomyces platensis MA7339 for overproduction of platencin and congeners.

M. Smanski, B. Shen, Zhiguo Yu, 2010, Organic letters.

Mechanisms of self-resistance in the platensimycin- and platencin-producing Streptomyces platensis MA7327 and MA7339 strains.

M. Smanski, B. Shen, J. Rudolf, 2014, Chemistry & biology.

Isolation and structural elucidation of glucoside congeners of platencin from Streptomyces platensis SB12600

M. Smanski, B. Shen, M. Rateb, 2013, The Journal of Antibiotics.

Bacterial diterpene synthases: new opportunities for mechanistic enzymology and engineered biosynthesis.

M. Smanski, B. Shen, Ryan M. Peterson, 2012, Current opinion in chemical biology.

Dedicated ent-kaurene and ent-atiserene synthases for platensimycin and platencin biosynthesis

M. Smanski, B. Shen, Zhiguo Yu, 2011, Proceedings of the National Academy of Sciences.

Expression of the platencin biosynthetic gene cluster in heterologous hosts yielding new platencin congeners.

M. Smanski, B. Shen, Zhiguo Yu, 2012, Journal of natural products.

Phosphorylation-specific status of RNAi triggers in pharmacokinetic and biodistribution analyses

Darren H. Wakefield, S. Kanner, D. Lewis, 2016, Nucleic acids research.

Platensimycin and platencin biosynthesis in Streptomyces platensis, showcasing discovery and characterization of novel bacterial diterpene synthases.

M. Smanski, B. Shen, Ryan M. Peterson, 2012, Methods in enzymology.

Engineered Streptomyces platensis Strains That Overproduce Antibiotics Platensimycin and Platencin

M. Smanski, B. Shen, S. Rajski, 2009, Antimicrobial Agents and Chemotherapy.

Treatment of Chronically HBV-Infected Chimpanzees with RNA Interference Therapeutic ARC-520 LED to Potent Reduction of Viral MRNA, DNA and Proteins without Observed Drug Resistance

S. Kanner, D. Lewis, R. Gish, 2016 .