A. Mcnicol

发表

Mechanisms of oral bacteria-induced platelet activation.

S. Israels, A. Mcnicol, 2010, Canadian journal of physiology and pharmacology.

Toll‐like receptor 4 ligand can differentially modulate the release of cytokines by human platelets

B. Pozzetto, O. Garraud, F. Cognasse, 2008, British journal of haematology.

Effects of the mitogen-activated protein (MAP) kinase kinase inhibitor 2-(2'-amino-3'-methoxyphenyl)-oxanaphthalen-4-one (PD98059) on human platelet activation.

S. Israels, A. Mcnicol, C. Philpott, 1998, Biochemical pharmacology.

Cellular prion protein is released on exosomes from activated platelets.

S. Booth, Catherine Robertson, M. Coulthart, 2006, Blood.

A role for intracellular histamine in collagen-induced platelet aggregation.

A. Becker, J. Gerrard, A. Mcnicol, 1990, Blood.

Incorporation of map kinases into the platelet cytoskeleton.

S. Israels, A. Mcnicol, T. S. Shibou, 2001, Thrombosis research.

Identification of Patients with Storage Pool Deficiency Using ATP Release and Dense Granule Counts.

S. Israels, A. Mcnicol, C. Robertson, 1997, Hematology.

Expression of functional recombinant mosquito salivary apyrase: A potential therapeutic platelet aggregation inhibitor

A. James, A. Mcnicol, D. Sun, 2006, Platelets.

Platelets and anti-platelet therapy.

S. Israels, A. Mcnicol, 2003, Journal of pharmacological sciences.

implications for mechanisms of pathogenesis familial platelet disorder with predisposition to acute myelogenous leukemia: In vitro analyses of known and novel RUNX1/AML1 mutations in dominant

S. Antonarakis, C. Rossier, S. Israels, 2013 .

Post-receptor events associated with thrombin-induced platelet activation.

J. Gerrard, A. Mcnicol, 1993, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

CD63 Associates with the αIIbβ3 Integrin-CD9 Complex on the Surface of Activated Platelets

S. Israels, E. McMillan-Ward, A. Mcnicol, 2001, Thrombosis and Haemostasis.

Platelet dense granules: structure, function and implications for haemostasis.

S. Israels, A. Mcnicol, 1999, Thrombosis research.

The effects of genistein on platelet function are due to thromboxane receptor antagonism rather than inhibition of tyrosine kinase.

A. Mcnicol, 1993, Prostaglandins, leukotrienes, and essential fatty acids.

Vanadate activates platelets by enhancing arachidonic acid release.

J. Gerrard, A. Mcnicol, C. Robertson, 1993, Blood.

Vanadate activates platelets by enhancing arachidonic acid release

J. Gerrard, A. Mcnicol, C. Robertson, 1993 .

Bleeding disorders: characterization, dental considerations and management.

S. Israels, A. Mcnicol, N. Schwetz, 2006, Journal.

A role for protein kinase C in the membrane fusion necessary for platelet granule secretion.

S. Israels, E. Cragoe, J. Park, 1989, Blood.

6 – Protein Kinase C and Granule Membrane Fusion in Platelets

J. Gerrard, A. Mcnicol, S. P. Saxena, 1993 .

Quantification of a novel dense granule protein (granulophysin) in platelets of patients with dense granule storage pool deficiency

S. Israels, A. Greenberg, A. Mcnicol, 1992 .

Quantification of a novel dense granule protein (granulophysin) in platelets of patients with dense granule storage pool deficiency.

J. White, S. Israels, A. Greenberg, 1992, Blood.

Agonist-induced inositol phospholipid metabolism and Ca++ flux in human platelet activation.

D. Macintyre, A. Mcnicol, W. Pollock, 1985, Advances in experimental medicine and biology.

Translocation and phosphorylation of cytosolic phospholipase A2 in activated platelets.

A. Mcnicol, T. S. Shibou, 1998, Thrombosis research.

Human platelets can discriminate between various bacterial LPS isoforms via TLR4 signaling and differential cytokine secretion.

B. Pozzetto, O. Garraud, F. Cognasse, 2012, Clinical immunology.

A role for immunoglobulin G in donor-specific Streptococcus sanguis-induced platelet aggregation

T. Zelinski, A. Mcnicol, G. Bowden, 2006, Thrombosis and Haemostasis.

Inhibition of platelet-activating-factor-induced human platelet activation by prostaglandin D2. Differential sensitivity of platelet transduction processes and functional responses to inhibition by cyclic AMP.

D. Macintyre, A. Mcnicol, M. Bushfield, 1985, The Biochemical journal.

Further Studies on the Effects of the Intracellular Histamine Antagonist DPPE on Platelet Function.

A. Becker, J. Gerrard, A. Mcnicol, 1991, Platelets.

Bacteria-induced intracellular signalling in platelets

A. Mcnicol, 2015, Platelets.

A role for von Willebrand factor in Streptococcus sanguis-induced platelet activation

S. Israels, A. Mcnicol, E. Jackson, 2007, Thrombosis and Haemostasis.

Platelet dense granule membranes contain both granulophysin and P-selectin (GMP-140).

M. Nishibori, S. Israels, D. Bainton, 1992, Blood.

Rapid ultrastructural changes in the dense tubular system following platelet activation.

J. Gerrard, A. Mcnicol, C. Robertson, 1992, Blood.

Inhibition of collagen-induced platelet activation by arachidonyl trifluoromethyl ketone.

A. Mcnicol, B. Nickolaychuk, 1995, Biochemical pharmacology.

The Lysosomal Granule Membrane Protein, Lamp-2, Is also Present in Platelet Dense Granule Membranes

S. Israels, A. Mcnicol, C. Robertson, 1996, Thrombosis and Haemostasis.

Anisomycin does not activate p38MAPK in human platelets.

A. Mcnicol, C. Pampolina, 1999, Thrombosis research.

Suppression of Lymphocyte Mitogenesis by Tamoxifen: Studies on Protein Kinase C, Calmodulin and Calcium

I. Bérczi, É. Nagy, A. Mcnicol, 1999, Neuroimmunomodulation.

Markers of Platelet Activation Are Increased in Adolescents With Type 2 Diabetes

S. Israels, F. Cognasse, H. Dean, 2014, Diabetes Care.

Platelet activation by Streptococcus sanguinis is accompanied by MAP kinase phosphorylation

A. Mcnicol, E. Jackson, Ahmed Y Abdulrehman, 2013, Platelets.

Mechanism of Collagen Activation in Human Platelets*

A. Mcnicol, D. Roberts, R. Bose, 2004, Journal of Biological Chemistry.

Fibroblasts require protein kinase C activation to respond to hyaluronan with increased locomotion.

E. Turley, J. Gerrard, C. Hall, 2001, Matrix biology : journal of the International Society for Matrix Biology.

Thrombin receptor-activating peptide releases arachidonic acid from human platelets: a comparison with thrombin and trypsin.

A. Mcnicol, C. Robson, 1997, The Journal of pharmacology and experimental therapeutics.

Streptococcus sanguis-induced platelet activation involves two waves of tyrosine phosphorylation mediated by FcγRIIA and αIIbβ3

A. Mcnicol, C. Pampolina, Caroline Pampolina, 2005, Thrombosis and Haemostasis.

Histamine as an intracellular messenger in human platelets.

J. Gerrard, A. Mcnicol, S. P. Saxena, 1993, Advances in experimental medicine and biology.

Cyclic nucleotides inhibit MAP kinase activity in low-dose collagen-stimulated platelets.

A. Mcnicol, E. Jackson, 2010, Thrombosis research.

Inherited platelet‐storage pool deficiency associated with a high incidence of acute myeloid leukaemia

S. Israels, E. Israels, L. Israels, 1991, British journal of haematology.

In vitro analyses of known and novel RUNX1/AML1 mutations in dominant familial platelet disorder with predisposition to acute myelogenous leukemia: implications for mechanisms of pathogenesis.

Yoshiaki Ito, Joëlle Michaud, Hamish S Scott, 2002, Blood.

Platelet Morphology, Aggregation, and Secretion

J. Gerrard, A. Mcnicol, 1997 .

Defective thrombin-induced calcium changes and aggregation of Bernard-Soulier platelets are not associated with deficient moderate-affinity receptors.

J. Drouin, A. Mcnicol, M. Sutherland, 1996, Arteriosclerosis, thrombosis, and vascular biology.

Evidence for a role of mitogen-activated protein kinases in proliferating and differentiating odontogenic epithelia of inflammatory and developmental cysts.

A. Mcnicol, J. Gilchrist, C. Birek, 2002, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics.

Histamine as an intracellular messenger.

G. Glavin, J. Gerrard, A. Mcnicol, 1990, Biochemical pharmacology.

Phospholipase C activity in platelets from Bernard-Soulier syndrome patients.

J. Gerrard, J. Drouin, A. Mcnicol, 1993, Arteriosclerosis and thrombosis : a journal of vascular biology.

The empty sack syndrome: a platelet storage pool deficiency associated with empty dense granules

S. Israels, J. Gerrard, A. Mcnicol, 1994, British journal of haematology.

The Inflammatory Role of Platelets via Their TLRs and Siglec Receptors

B. Pozzetto, O. Garraud, F. Cognasse, 2015, Front. Immunol..

Inhibition of the MEK/ERK pathway has no effect on agonist-induced aggregation of human platelets.

A. Mcnicol, E. Jackson, 2003, Biochemical pharmacology.

The protein CD63 is in platelet dense granules, is deficient in a patient with Hermansky-Pudlak syndrome, and appears identical to granulophysin.

M. Nishibori, J. Gerrard, A. Mcnicol, 1993, The Journal of clinical investigation.

Impaired Signal Transduction in Neonatal Platelets

S. Israels, E. McMillan-Ward, A. Mcnicol, 1999, Pediatric Research.

Streptococcus sanguinis‐induced cytokine release from platelets

F. Cognasse, O. Garraud, H. Hamzeh-Cognasse, 2011, Journal of thrombosis and haemostasis : JTH.

Platelet storage pool deficiency, leukemia, and myelodysplastic syndromes.

J. Gerrard, A. Mcnicol, 1992, Leukemia & lymphoma.

Platelet storage pool deficiency: diagnosis in patients with prolonged bleeding times and normal platelet aggregation

S. Israels, J. Gerrard, A. Mcnicol, 1990, British journal of haematology.

Beyond hemostasis: the role of platelets in inflammation, malignancy and infection.

S. Israels, A. Mcnicol, 2008, Cardiovascular & hematological disorders drug targets.

Deficient Thromboxane Synthesis and Response in Platelets from Premature Infants

S. Israels, A. Mcnicol, C. Robertson, 1997, Pediatric Research.

Possible mechanisms of the potentiation of blood-platelet activation by adrenaline.

D. Macintyre, A. Mcnicol, M. Bushfield, 1987, The Biochemical journal.

Tumour‐promoting phorbol esters inhibit agonist‐induced phosphatidate formation and Ca2+ flux in human platelets

A. H. Drummond, D. Macintyre, A. Mcnicol, 1985, FEBS letters.

The Effects of an Inhibitor of Diglyceride Lipase on Collagen-Induced Platelet Activation

G. Ortar, A. Mcnicol, E. Jackson, 2013, The Journal of Pharmacology and Experimental Therapeutics.

Evidence for a Role for Phospholipase C, but not Phospholipase A2, in Platelet Activation in Response to Low Concentrations of Collagen

A. Mcnicol, B. Nickolaychuk, L. Lockhart, 2001, Thrombosis and Haemostasis.

The phospholipase C inhibitor U73122 inhibits phorbol ester-induced platelet activation.

A. Mcnicol, L. Lockhart, Leslie K. Lockhart, 1999, The Journal of pharmacology and experimental therapeutics.

In vivo measurement of thromboxane B2 and 6-keto-prostaglandin F1 alpha in humans in response to a standardized vascular injury and the influence of aspirin.

S. Taback, J. Docherty, N. Kobrinsky, 1989, Circulation.

Increased phosphatidic acid and decreased lysophosphatidic acid in response to thrombin is associated with inhibition of platelet aggregation.

J. Gerrard, A. Mcnicol, P. Robinson, 1993, Biochemistry and cell biology = Biochimie et biologie cellulaire.

NF-κB Links TLR2 and PAR1 to Soluble Immunomodulator Factor Secretion in Human Platelets

B. Payrastre, B. Pozzetto, O. Garraud, 2017, Front. Immunol..

Streptococcus sanguinis-induced cytokine and matrix metalloproteinase-1 release from platelets

O. Garraud, F. Cognasse, H. Hamzeh-Cognasse, 2014, BMC Immunology.

Endogenous and pharmacological mechanisms for the regulation of human platelet cytosolic free Ca2+.

D. Macintyre, A. Mcnicol, M. Bushfield, 1985, Nouvelle revue francaise d'hematologie.

Histamine formed in stimulated human platelets is cytoplasmic.

A. Becker, J. Gerrard, A. Mcnicol, 1989, Biochemical and biophysical research communications.

A role for intracellular histamine in ultrastructural changes induced in platelets by phorbol esters.

J. Gerrard, A. Mcnicol, L. J. Brandes, 1989, Arteriosclerosis.

Evidence for two mechanisms of thrombin-induced platelet activation: one proteolytic, one receptor mediated.

D. Macintyre, J. Gerrard, A. Mcnicol, 1989, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Biochemical and Ultrastructural Studies Suggest that the Effects of Thapsigargin on Human Platelets Are Mediated by Changes in Intracellular Calcium but not by Intracellular Histamine

O. Thastrup, J. Gerrard, A. Mcnicol, 1992, Thrombosis and Haemostasis.

Streptococcus sanguis-induced platelet activation involves two waves of tyrosine phosphorylation mediated by FcgammaRIIA and alphaIIbbeta3.

A. Mcnicol, Caroline Pampolina, 2005, Thrombosis and haemostasis.

Platelets from bleeding Simmental cattle mobilize calcium, phosphorylate myosin light chain and bind normal numbers of fibrinogen molecules but have abnormal cytoskeletal assembly and aggregation in response to ADP.

A. Mcnicol, C. Robertson, Gene P. Searcy, 1994, Thrombosis and haemostasis.