M. Ijsseldijk

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Treatment of Uremic Anemia with Recombinant Erythropoietin also Reduces the Defects in Platelet Adhesion and Aggregation Caused by Uremic Plasma

J. Sixma, P. D. de Groot, J. Zwaginga, 1991, Thrombosis and Haemostasis.

A3 Domain Is Essential for Interaction of von Willebrand Factor with Collagen Type III

J. Sixma, P. D. de Groot, M. Schiphorst, 1996, Thrombosis and Haemostasis.

Quantification of fibrin deposition in flowing blood with peroxidase-labeled fibrinogen. High shear rates induce decreased fibrin deposition and appearance of fibrin monomers.

J. Sixma, P. D. de Groot, P. Tijburg, 1991, Arteriosclerosis and thrombosis : a journal of vascular biology.

High von Willebrand factor concentration compensates a relative adhesion defect in uremic blood.

J. Sixma, P. D. de Groot, J. Zwaginga, 1990, Blood.

Platelet adhesion to laminin: role of Ca2+ and Mg2+ ions, shear rate, and platelet membrane glycoproteins.

A. Sonnenberg, J. Sixma, P. D. de Groot, 1992, Blood.

Platelet adhesion to fibronectin in flow: the importance of von Willebrand factor and glycoprotein Ib.

J. Sixma, P. D. de Groot, E. Orlando, 1995, Blood.

Role of ADP Receptor P2Y12 in Platelet Adhesion and Thrombus Formation in Flowing Blood

P. Nurden, J. Sixma, P. D. de Groot, 2002, Arteriosclerosis, thrombosis, and vascular biology.

Impaired platelet adhesion to lysed fibrin, whereas neutrophil adhesion remains intact under conditions of flow

J. Sixma, P. D. de Groot, J. Zwaginga, 2006, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

The low-frequency allele of the platelet collagen signaling receptor glycoprotein VI is associated with reduced functional responses and expression.

W. Ouwehand, N. Watkins, A. Goodall, 2003, Blood.

Reduced platelet adhesion in flowing blood to fibrinogen by alterations in segment γ316–322, part of the fibrin‐specific region *

J. Sixma, P. D. de Groot, S. Lord, 2002, British journal of haematology.

Defects in platelet adhesion and aggregate formation in uremic bleeding disorder can be attributed to factors in plasma.

J. Sixma, P. D. de Groot, J. Zwaginga, 1991, Arteriosclerosis and thrombosis : a journal of vascular biology.

Functional studies on platelet adhesion with recombinant von Willebrand factor type 2B mutants R543Q and R543W under conditions of flow.

J. Sixma, P. D. de Groot, M. Schiphorst, 1997, Blood.

A tripeptide mimetic of von Willebrand factor residues 981–983 enhances platelet adhesion to fibrinogen by signaling through integrin βIIbβ3

C. Gahmberg, E. Koivunen, J. Akkerman, 2005 .

Platelet adhesion to fibronectin in flow: dependence on surface concentration and shear rate, role of platelet membrane glycoproteins GP IIb/IIIa and VLA-5, and inhibition by heparin.

J. Sixma, P. D. de Groot, M. Ijsseldijk, 1994, Blood.

Thrombopoietin increases platelet adhesion under flow and decreases rolling

J. Sixma, P. D. de Groot, J. Akkerman, 2003, British journal of haematology.

Platelet Activation by Oxidized Low Density Lipoprotein Is Mediated by Cd36 and Scavenger Receptor-A

P. Lenting, T. V. van Berkel, J. Akkerman, 2007, Arteriosclerosis, thrombosis, and vascular biology.

Type I von Willebrand disease, subtype ‘platelet low’: decreased platelet adhesion can be explained by low synthesis of von Willebrand factor in endothelial cells

J. Sixma, P. Mannucci, M. Moia, 1993, British journal of haematology.

Absence of Fibrinogen in Afibrinogenemia Results in Large but Loosely Packed Thrombi under Flow Conditions

J. Sixma, P. D. de Groot, J. Zwaginga, 2001, Thrombosis and Haemostasis.

Platelet adhesion to collagen in healthy volunteers is influenced by variation of both α2β1 density and von Willebrand factor

J. Sixma, P. D. de Groot, P. Slootweg, 2000 .

Platelet adhesion to collagen in healthy volunteers is influenced by variation of both alpha(2)beta(1) density and von Willebrand factor.

J. Sixma, P. D. de Groot, P. Slootweg, 2000, Blood.

adhesion defect in uremic blood High von Willebrand factor concentration compensates a relative

J. Sixma, J. Zwaginga, M. Ijsseldijk, 2011 .

Adhesion of blood platelets is inhibited by VCL, a recombinant fragment (leucine504 to lysine728) of von Willebrand factor.

J. Sixma, P. D. de Groot, A. Panet, 1996, Arteriosclerosis, thrombosis, and vascular biology.

and platelet membrane glycoproteins Platelet adhesion to laminin: role of Ca2+ and Mg2+ ions, shear rate,

A. Sonnenberg, J. Sixma, M. Ijsseldijk, 2011 .

A selective medium for the two major subgroups of the bacterium Streptococcus mutans isolated from human dental plaque and saliva.

W. H. van Palenstein Helderman, J H Huis in 't Veld, M. Ijsseldijk, 1983, Archives of oral biology.

Novel molecular defect in the platelet ADP receptor P2Y12 of a patient with haemorrhagic diathesis

R. Slingerland, B. Dikkeschei, A. Abbes, 2007, Clinical chemistry and laboratory medicine.

Lipoprotein(a) inhibits collagen-induced aggregation of thrombocytes.

J. Sixma, T. Kenner, G. Kostner, 1996, Arteriosclerosis, thrombosis, and vascular biology.

The Platelet Adhesion Capacity to Subendothelial Matrix and Collagen in a Flow Model during Storage of Platelet Concentrates for 7 Days

C. Homburg, D. de Korte, M. Ijsseldijk, 1994, Thrombosis and Haemostasis.

Adhesive Domains in the Collagen III Fragment α1(III)CB4 that Support α2β1- and von Willebrand Factor-mediated Platelet Adhesion under Flow Conditions

J. Sixma, P. D. de Groot, E. Huizinga, 1999, Thrombosis and Haemostasis.

Thrombogenicity of vascular cells. Comparison between endothelial cells isolated from different sources and smooth muscle cells and fibroblasts.

J J Sixma, J J Zwaginga, J. Sixma, 1990, Arteriosclerosis.

von Willebrand Factor without the A2 Domain Is Resistant to Proteolysis

J. Sixma, P. D. de Groot, M. Schiphorst, 1997, Thrombosis and Haemostasis.

The effect of recombinant IgG antibodies against the leucine-33 form of the platelet β3 integrin (HPA-1a) on platelet function

W. Ouwehand, N. Watkins, P. D. de Groot, 2004, Thrombosis and Haemostasis.

Identification of the primary collagen-binding surface on human glycoprotein VI by site-directed mutagenesis and by a blocking phage antibody.

Richard W Farndale, Ashley Buckle, W. Ouwehand, 2004, Blood.

Recombinant vWF Type 2A Mutants R834Q and R834W Show a Defect in Mediating Platelet Adhesion to Collagen, Independent of Enhanced Sensitivity to a Plasma Protease

J. Sixma, P. D. de Groot, M. Schiphorst, 1999, Thrombosis and Haemostasis.

Platelet thrombus formation on collagen at high shear rates is mediated by von Willebrand factor-glycoprotein Ib interaction and inhibited by von Willebrand factor-glycoprotein IIb/IIIa interaction.

J. Sixma, P. D. de Groot, M. Schiphorst, 2000, Arteriosclerosis, thrombosis, and vascular biology.

A new perfusion chamber to detect platelet adhesion using a small volume of blood.

J. Sixma, P. D. de Groot, M. Ijsseldijk, 1998, Thrombosis research.

Role of the fibrinogen gamma-chain sequence gamma316-322 in platelet-mediated clot retraction.

J. Remijn, M. Ijsseldijk, P. G. D. Groot, 2003, Journal of thrombosis and haemostasis : JTH.

ALX-0081 Nanobody™, an Engineered Bivalent Anti-Thrombotic Drug Candidate with Improved Efficacy and Safety as Compared to the Marketed Drugs.

K. Silence, P. Casteels, H. Jonckheere, 2006 .