A. Barbuti

发表

In Vitro Epigenetic Reprogramming of Human Cardiac Mesenchymal Stromal Cells into Functionally Competent Cardiovascular Precursors

M. Capogrossi, C. Gaetano, V. Meraviglia, 2012, PloS one.

Human cardiac and bone marrow stromal cells exhibit distinctive properties related to their origin.

Qingbo Xu, M. Mayr, M. Capogrossi, 2011, Cardiovascular research.

Results 3 . 1 CStC and BMStC morphology , immunophenotype , and molecular marker expression

Qingbo Xu, M. Mayr, M. Capogrossi, 2011 .

Localization of Pacemaker Channels in Lipid Rafts Regulates Channel Kinetics

D. DiFrancesco, A. Barbuti, B. Gravante, 2004, Circulation research.

Modulation of the intrinsic neuronal excitability by multifunctional liposomes tailored for the treatment of Alzheimer’s disease

M. Masserini, F. Re, A. Panariti, 2018, International journal of nanomedicine.

Neuropeptide Y Is an Essential In Vivo Developmental Regulator of Cardiac ICa,L

R. Palmiter, R. Robinson, S. Steinberg, 2003, Circulation research.

The expression of the rare caveolin-3 variant T78M alters cardiac ion channels function and membrane excitability

S. Severi, R. Cappato, M. Francolini, 2017, Cardiovascular research.

Embryonic Stem Cell–Derived CD166+ Precursors Develop Into Fully Functional Sinoatrial-Like Cells

S. Benedetti, S. Antonini, D. DiFrancesco, 2013, Circulation research.

Human iPSC modelling of a familial form of atrial fibrillation reveals a gain of function of If and ICaL in patient-derived cardiomyocytes

M. Memo, A. Consiglio, Á. Raya, 2019, Cardiovascular research.

Optical Investigation of Action Potential and Calcium Handling Maturation of hiPSC-Cardiomyocytes on Biomimetic Substrates

M. Regnier, D. Mack, C. Poggesi, 2019, International journal of molecular sciences.

Molecular composition and functional properties of f-channels in murine embryonic stem cell-derived pacemaker cells.

D. DiFrancesco, M. Baruscotti, A. Barbuti, 2009, Journal of molecular and cellular cardiology.

Heart rate reduction via selective 'funny' channel blockers.

D. DiFrancesco, A. Bucchi, M. Baruscotti, 2007, Current opinion in pharmacology.

Chinese natural compound decreases pacemaking of rabbit cardiac sinoatrial cells by targeting second messenger regulation of f-channels

Yi Wang, D. DiFrancesco, Yi Wang, 2022, eLife.

The natural compound TMYX reduces SAN cells rate by antagonizing the cAMP modulation of f-channels

Yi Wang, D. DiFrancesco, Yi Wang, 2021, bioRxiv.

Cardiac mesoangioblasts are committed, self-renewable progenitors, associated with small vessels of juvenile mouse ventricle

R. Latini, M. Sampaolesi, G. Cossu, 2008, Cell Death and Differentiation.

Liraglutide preserves CD34+ stem cells from dysfunction Induced by high glucose exposure

E. Sacco, P. Fiorina, A. Raucci, 2022, Cardiovascular Diabetology.

Anacardic acid and thyroid hormone enhance cardiomyocytes production from undifferentiated mouse ES cells along functionally distinct pathways

F. Trimarchi, C. Colussi, S. Mattiussi, 2016, Endocrine.

PCSK9 deficiency rewires heart metabolism and drives heart failure with preserved ejection fraction

E. Donetti, N. Mitro, P. Benzoni, 2021, European heart journal.

Preferential myofibroblast differentiation of cardiac mesenchymal progenitor cells in the presence of atrial fibrillation

D. DiFrancesco, M. C. Lionetti, G. Pompilio, 2017, Translational research : the journal of laboratory and clinical medicine.

Block of the background K(+) channel TASK-1 contributes to arrhythmogenic effects of platelet-activating factor.

R. Robinson, Takao Shimizu, S. Ishii, 2002, American journal of physiology. Heart and circulatory physiology.

Activation of Protein Kinase C ϵ Inhibits the Two-pore Domain K+ Channel, TASK-1, Inducing Repolarization Abnormalities in Cardiac Ventricular Myocytes*

R. Robinson, S. Feinmark, A. Symes, 2004, Journal of Biological Chemistry.

OP-EHEA210437 1..13

E. Donetti, N. Mitro, P. Benzoni, 2021 .

HCN ion channels and accessory proteins in epilepsy: genetic analysis of a large cohort of patients and review of the literature

B. Castellotti, C. Gellera, S. Franceschetti, 2019, Epilepsy Research.

Recessive Loss-of-Function Mutation in the Pacemaker HCN2 Channel Causing Increased Neuronal Excitability in a Patient with Idiopathic Generalized Epilepsy

S. Franceschetti, D. DiFrancesco, C. Ferrarese, 2011, The Journal of Neuroscience.

A detailed characterization of the hyperpolarization-activated “funny” current (If) in human-induced pluripotent stem cell (iPSC)–derived cardiomyocytes with pacemaker activity

A. Rossini, P. Benzoni, P. Dell’Era, 2021, Pflügers Archiv - European Journal of Physiology.

Identification of the Molecular Site of Ivabradine Binding to HCN4 Channels

M. Nardini, M. Bolognesi, D. DiFrancesco, 2013, PloS one.

Human cord blood CD34+ progenitor cells acquire functional cardiac properties through a cell fusion process.

M. Pesce, M. Capogrossi, P. Devanna, 2011, American journal of physiology. Heart and circulatory physiology.

processcardiac properties through a cell fusion

M. Pesce, M. Capogrossi, P. Devanna, 2011 .

The 'hearty' fat: adipocytes as a source of functional cardiomyocytes.

A. Barbuti, 2010, Cardiovascular research.

Postexercise autonomic function after repeated-sprints training

G. Merati, L. Agnello, G. Vernillo, 2015, European Journal of Applied Physiology.

A caveolin-binding domain in the HCN4 channels mediates functional interaction with caveolin proteins.

D. DiFrancesco, M. Baruscotti, A. Barbuti, 2012, Journal of molecular and cellular cardiology.

Interaction of the Pacemaker Channel HCN1 with Filamin A*

D. DiFrancesco, C. Viscomi, A. Barbuti, 2004, Journal of Biological Chemistry.

A Loss-of-Function HCN4 Mutation Associated With Familial Benign Myoclonic Epilepsy in Infancy Causes Increased Neuronal Excitability

B. Castellotti, T. Gnecchi-Ruscone, C. Gellera, 2018, Front. Mol. Neurosci..

MiR-320a as a Potential Novel Circulating Biomarker of Arrhythmogenic CardioMyopathy

M. Giacca, A. Dello Russo, C. Tondo, 2017, Scientific Reports.

Virus-free iPS-derived cardiomyocytes: a new piece in the puzzle of patient-tailored therapies.

A. Barbuti, 2011, Cardiovascular research.

Stem Cell–Derived Nodal-Like Cardiomyocytes as a Novel Pharmacologic Tool: Insights from Sinoatrial Node Development and Function

R. Robinson, A. Barbuti, 2015, Pharmacological Reviews.

The “Funny” Pacemaker Current

D. DiFrancesco, A. Bucchi, Georgia Bottelli, 2009 .

Higher cardiogenic potential of iPSCs derived from cardiac versus skin stromal cells.

L. Fassina, P. Pramstaller, C. Gaetano, 2016, Frontiers in bioscience.

The Pacemaker Current: From Basics to the Clinics

D. DiFrancesco, M. Baruscotti, A. Barbuti, 2007, Journal of cardiovascular electrophysiology.

HCN Channels and Cardiac Pacemaking

D. DiFrancesco, A. Bucchi, M. Baruscotti, 2018 .

Funny Current and Cardiac Rhythm: Insights from HCN Knockout and Transgenic Mouse Models

D. DiFrancesco, A. Bucchi, M. Baruscotti, 2012, Front. Physio..

HCN1 mutation spectrum: from neonatal epileptic encephalopathy to benign generalized epilepsy and beyond

K. Hamacher, C. Mercer, P. Striano, 2018, Brain : a journal of neurology.

Acetylation mediates Cx43 reduction caused by electrical stimulation.

P. Pramstaller, F. Recchia, M. Capogrossi, 2015, Journal of molecular and cellular cardiology.

Effects of repeated sprints training on fracture risk-associated miRNA

G. Banfi, G. Merati, G. Vernillo, 2018, Oncotarget.

The funny current: Even funnier than 40 years ago. Uncanonical expression and roles of HCN/f channels all over the body.

P. Benzoni, M. Pecchiari, A. Bucchi, 2021, Progress in biophysics and molecular biology.

A gain-of-function mutation in the cardiac pacemaker HCN4 channel increasing cAMP sensitivity is associated with familial Inappropriate Sinus Tachycardia

R. Cappato, T. Gnecchi-Ruscone, D. DiFrancesco, 2017, European heart journal.

A novel de novo HCN1 loss-of-function mutation in genetic generalized epilepsy causing increased neuronal excitability

B. Castellotti, C. Gellera, S. Franceschetti, 2018, Neurobiology of Disease.

Mesoangioblasts from ventricular vessels can differentiate in vitro into cardiac myocytes with sinoatrial-like properties.

G. Cossu, D. DiFrancesco, C. Brioschi, 2010, Journal of molecular and cellular cardiology.

The cardiac pacemaker current.

Annalisa Bucchi, Mirko Baruscotti, A. Bucchi, 2010, Journal of molecular and cellular cardiology.

Human derived cardiomyocytes: A decade of knowledge after the discovery of induced pluripotent stem cells

P. Benzoni, P. Dell’Era, A. Barbuti, 2016, Developmental dynamics : an official publication of the American Association of Anatomists.

Control of Cardiac Rate by “Funny” Channels in Health and Disease

Dario DiFrancesco, D. DiFrancesco, Andrea Barbuti, 2008, Annals of the New York Academy of Sciences.

Localization of f-channels to caveolae mediates specific beta2-adrenergic receptor modulation of rate in sinoatrial myocytes.

D. DiFrancesco, C. Brioschi, A. Barbuti, 2007, Journal of molecular and cellular cardiology.

Kinetic and ionic properties of the human HCN2 pacemaker channel

Dario DiFrancesco, Mirko Baruscotti, D. DiFrancesco, 2000, Pflügers Archiv.

Action of internal pronase on the f‐channel kinetics in the rabbit SA node

D. DiFrancesco, A. Moroni, M. Baruscotti, 1999, The Journal of physiology.

HCN2 Overexpression in Newborn and Adult Ventricular Myocytes: Distinct Effects on Gating and Excitability

R B Robinson, R. Robinson, B. Santoro, 2001, Circulation research.

25 – Stem Cell–Derived Sinoatrial-Like Cardiomyocytes as a Novel Pharmacological Tool

R. Robinson, A. Barbuti, 2018 .

Chemical modification of methionine residues of the phosphatidylcholine transfer protein from bovine liver. A spin-label study.

K. Wirtz, E. Quagliariello, D. van Loon, 1985, European journal of biochemistry.

Bone turnover response is linked to both acute and established metabolic changes in ultra-marathon runners

F. Schena, G. Banfi, G. Merati, 2017, Endocrine.

Modeling incomplete penetrance in arrhythmogenic cardiomyopathy by human induced pluripotent stem cell derived cardiomyocytes

P. Pramstaller, Eva König, V. Meraviglia, 2023, Computational and structural biotechnology journal.

Deep bradycardia and heart block caused by inducible cardiac-specific knockout of the pacemaker channel gene Hcn4

Nicola Montano, Dario DiFrancesco, Annalisa Bucchi, 2011, Proceedings of the National Academy of Sciences.

L. Carnevali, D. DiFrancesco, A. Bucchi, 2021, Frontiers in Neuroscience.

Effects of dronedarone on Acetylcholine‐activated current in rabbit SAN cells

D. DiFrancesco, C. Viscomi, M. Baruscotti, 2000, British journal of pharmacology.

Distribution of the pacemaker HCN4 channel mRNA and protein in the rabbit sinoatrial node.

R. Longhi, M. Boyett, H. Dobrzynski, 2009, Journal of molecular and cellular cardiology.

Plasminogen activator inhibitor-1 as a marker of cardiovascular response in professional mountain ultra-marathon runners

F. Schena, G. Banfi, G. Merati, 2017, Clinical chemistry and laboratory medicine.

Human iPSC modelling of a familial form of atrial fibrillation reveals a gain of function of I f and I CaL in patient-derived cardiomyocytes

E. Crescini, A. Consiglio, P. Benzoni, 2019 .

A novel de novo HCN1 loss-of-function mutation in genetic generalized epilepsy causing increased neuronal excitability

B. Castellotti, C. Gellera, S. Franceschetti, 2018, Neurobiology of Disease.

Dual role of miR-1 in the development and function of sinoatrial cells.

P. Benzoni, A. Bucchi, M. Baruscotti, 2021, Journal of molecular and cellular cardiology.

A caveolin-binding domain in the HCN4 channels mediates functional interaction with caveolin proteins.

D. DiFrancesco, M. Baruscotti, A. Barbuti, 2012, Journal of molecular and cellular cardiology.

Striatin knock out induces a gain of function of INa and impaired Ca2+ handling in mESC-derived cardiomyocytes.

P. Benzoni, A. Bucchi, M. Baruscotti, 2024, Acta physiologica.

Caveolin-3 and Caveolin-1 Interaction Decreases Channel Dysfunction Due to Caveolin-3 Mutations

P. Benzoni, S. Baratto, A. Bucchi, 2024, International Journal of Molecular Sciences.

Generation of human induced pluripotent stem cells (EURACi001-A, EURACi002-A, EURACi003-A) from peripheral blood mononuclear cells of three patients carrying mutations in the CAV3 gene.

P. Pramstaller, V. Meraviglia, B. Motta, 2018, Stem cell research.