Carlos G. Hidalgo

发表

Titin-Actin Interaction: PEVK-Actin-Based Viscosity in a Large Animal

Siegfried Labeit, H. Granzier, S. Labeit, 2011, Journal of biomedicine & biotechnology.

Effect of exercise training on post-translational and post-transcriptional regulation of titin stiffness in striated muscle of wild type and IG KO mice.

H. Granzier, Carlos G. Hidalgo, Chandra Saripalli, 2014, Archives of biochemistry and biophysics.

Tuning the molecular giant titin through phosphorylation: role in health and disease.

H. Granzier, Carlos G. Hidalgo, 2013, Trends in cardiovascular medicine.

Shortening of the Elastic Tandem Immunoglobulin Segment of Titin Leads to Diastolic Dysfunction

Caiying Guo, H. Granzier, Mei Methawasin, 2013, Circulation.

PKC Phosphorylation of Titin’s PEVK Element: A Novel and Conserved Pathway for Modulating Myocardial Stiffness

Siegfried Labeit, Henk Granzier, Brian R. Anderson, 2009, Circulation research.

Phosphorylating Titin's Cardiac N2B Element by ERK2 or CaMKIIδ Lowers the Single Molecule and Cardiac Muscle Force.

Brian R. Anderson, G. Del Favero, O. Sbaizero, 2015, Biophysical journal.

The multifunctional Ca(2+)/calmodulin-dependent protein kinase II delta (CaMKIIδ) phosphorylates cardiac titin's spring elements.

H. Granzier, Mei Methawasin, G. Tsaprailis, 2013, Journal of molecular and cellular cardiology.

Excision of titin's cardiac PEVK spring element abolishes PKCalpha-induced increases in myocardial stiffness.

H. Granzier, M. Gotthardt, B. Hudson, 2010, Journal of molecular and cellular cardiology.

Altered contractility of skeletal muscle in mice deficient in titin's M-band region.

C. Ottenheijm, H. Granzier, M. Gotthardt, 2009, Journal of molecular biology.

CaMKII effects on inotropic but not lusitropic force frequency responses require phospholamban.

Mark E. Anderson, X. Wehrens, H. Granzier, 2012, Journal of molecular and cellular cardiology.

Nebulin Alters Cross-bridge Cycling Kinetics and Increases Thin Filament Activation

C. Ottenheijm, H. Granzier, S. Ford, 2009, The Journal of Biological Chemistry.

Recessive truncating titin gene, TTN, mutations presenting as centronuclear myopathy

Nasim Vasli, Jocelyn Laporte, Alan H Beggs, 2013, Neurology.

Troponin activator augments muscle force in nemaline myopathy patients with nebulin mutations

C. Ottenheijm, A. Beggs, N. Clarke, 2013, Journal of Medical Genetics.

Experimentally Increasing Titin Compliance in a Novel Mouse Model Attenuates the Frank-Starling Mechanism But Has a Beneficial Effect on Diastole

C. Ottenheijm, H. Granzier, Mei Methawasin, 2014, Circulation.

Mouse and computational models link Mlc2v dephosphorylation to altered myosin kinetics in early cardiac disease.

Andrew D McCulloch, Richard L Moss, Ju Chen, 2012, The Journal of clinical investigation.

Right Ventricular Diastolic Impairment in Patients With Pulmonary Arterial Hypertension

W. Paulus, N. Westerhof, M. Humbert, 2013, Circulation.

Protein Changes Contributing to Right Ventricular Cardiomyocyte Diastolic Dysfunction in Pulmonary Arterial Hypertension

N. Westerhof, M. Humbert, C. Ottenheijm, 2014, Journal of the American Heart Association.

Titin based viscosity in ventricular physiology: an integrative investigation of PEVK-actin interactions.

H. Granzier, M. Gotthardt, M. Radke, 2011, Journal of molecular and cellular cardiology.

Hyperphosphorylation of Mouse Cardiac Titin Contributes to Transverse Aortic Constriction-Induced Diastolic Dysfunction

H. Granzier, Carlos G. Hidalgo, Chandra Saripalli, 2011, Circulation research.

Shortening of Titin’s Elastic Tandem Ig Segment Leads to Diastolic Dysfunction

Caiying Guo, H. Granzier, Mei Methawasin, 2013 .

Mouse and computational models link Mlc2v dephosphorylation to altered myosin kinetics in early cardiac disease.

A. McCulloch, Yusu Gu, N. Dalton, 2012, The Journal of clinical investigation.

Effect of diastolic pressure on MLC2v phosphorylation in the rat left ventricle.

H. Granzier, Jun Peng, K. Campbell, 2006, Archives of biochemistry and biophysics.