N. Tricoche

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An Integrated Approach to Identify New Anti-Filarial Leads to Treat River Blindness, a Neglected Tropical Disease

M. Mitreva, M. Arkin, J. Janetka, 2021, Pathogens.

Preliminary evaluations of 3-dimensional human skin models for their ability to facilitate in vitro the long-term development of the debilitating obligatory human parasite Onchocerca volvulus

J. Hansmann, S. Lustigman, N. Tricoche, 2020, PLoS neglected tropical diseases.

Optimizing 3-dimensional human skin models to facilitate long-term development of Onchocerca volvulus, a debilitating obligatory human parasite

J. Hansmann, S. Lustigman, N. Tricoche, 2020, bioRxiv.

DNA Immunization with Hepatitis C Virus (HCV) Polycistronic Genes or Immunization by HCV DNA Priming-Recombinant Canarypox Virus Boosting Induces Immune Responses and Protection from Recombinant HCV-Vaccinia Virus Infection in HLA-A2.1-Transgenic Mice

M. Perkus, P. Pancholi, A. Prince, 2003, Journal of Virology.

Short-course quinazoline drug treatments are effective in the Litomosoides sigmodontis and Brugia pahangi jird models

H. M. Petrassi, Malina A. Bakowski, A. Hoerauf, 2019, International journal for parasitology. Drugs and drug resistance.

Repurposing Auranofin as a Lead Candidate for Treatment of Lymphatic Filariasis and Onchocerciasis

Brian M. Suzuki, J. Gut, M. Arkin, 2015, PLoS neglected tropical diseases.

Development of a preliminary in vitro drug screening assay based on a newly established culturing system for pre-adult fifth-stage Onchocerca volvulus worms

D. Voronin, S. Lustigman, M. T. Suderman, 2019, PLoS neglected tropical diseases.

Pyrvinium Pamoate and Structural Analogs Are Early Macrofilaricide Leads

A. Renslo, Ian A. Vogel, B. Beerntsen, 2022, Pharmaceuticals.

Repositioning of an existing drug for the neglected tropical disease Onchocerciasis

Amanda L. Garner, Kim D. Janda, K. Janda, 2010, Proceedings of the National Academy of Sciences.

Macrofilaricidal Benzimidazole–Benzoxaborole Hybrids as an Approach to the Treatment of River Blindness: Part 2. Ketone Linked Analogs

J. McKerrow, S. Lustigman, J. Plattner, 2019, ACS infectious diseases.

Macrofilaricidal Benzimidazole–Benzoxaborole Hybrids as an Approach to the Treatment of River Blindness: Part 1. Amide Linked Analogs

K. Jarnagin, A. Hoerauf, J. McKerrow, 2019, ACS infectious diseases.

Onchocerca volvulus Molting Inhibitors Identified through Scaffold Hopping.

K. Janda, Sacha Javor, S. Lustigman, 2015, ACS infectious diseases.

Dual Protonophore–Chitinase Inhibitors Dramatically Affect O. volvulus Molting

K. Janda, S. Lustigman, N. Tricoche, 2014, Journal of medicinal chemistry.

Characterization of the immune response against hepatitis C infection in recovered, and chronically infected chimpanzees

D. Anthony, A. Prince, B. Brotman, 2002, Journal of viral hepatitis.

gC1qR expression in chimpanzees with resolved and chronic infection: potential role of HCV core/gC1qR-mediated T cell suppression in the outcome of HCV infection.

A. Prince, B. Brotman, Z. Yao, 2006, Virology.

Serological Assays Estimate Highly Variable SARS-CoV-2 Neutralizing Antibody Activity in Recovered COVID-19 Patients

P. Bieniasz, C. Hillyer, Y. Weisblum, 2020, Journal of Clinical Microbiology.

Serological Assays Estimate Highly Variable SARS-CoV-2 Neutralizing Antibody Activity in Recovered COVID19 Patients

P. Bieniasz, C. Hillyer, Y. Weisblum, 2020, medRxiv.

Serological Assays Estimate Highly Variable SARS-CoV-2 Neutralizing Antibody Activity in Recovered COVID19 Patients

P. Bieniasz, C. Hillyer, Y. Weisblum, 2020, medRxiv.

The Adjuvanticity of an O. volvulus-Derived rOv-ASP-1 Protein in Mice Using Sequential Vaccinations and in Non-Human Primates

P. Marx, Lu Lu, Shibo Jiang, 2012, PloS one.

DNA prime-canarypox boost with polycistronic hepatitis C virus (HCV) genes generates potent immune responses to HCV structural and nonstructural proteins.

M. Perkus, P. Pancholi, A. Prince, 2000, The Journal of infectious diseases.

Antibody responses against the vaccine antigens Ov-103 and Ov-RAL-2 are associated with protective immunity to Onchocerca volvulus infection in both mice and humans

P. Hotez, M. Bottazzi, B. Zhan, 2019, PLoS neglected tropical diseases.

Evidence for Protection against Chronic Hepatitis C Virus Infection in Chimpanzees by Immunization with Replicating Recombinant Vaccinia Virus

A. Folgori, F. Cosset, M. Dreux, 2008, Journal of Virology.

Attempted therapeutic immunization in a chimpanzee chronic HBV carrier with a high viral load

K. Murthy, A. Prince, Dong‐Hun Lee, 2006, Journal of medical primatology.

Exposure to low infective doses of HCV induces cellular immune responses without consistently detectable viremia or seroconversion in chimpanzees.

M. Perkus, L. Tobler, A. Prince, 2003, Virology.

Protection against chronic hepatitis C virus infection after rechallenge with homologous, but not heterologous, genotypes in a chimpanzee model.

A. Prince, Dong‐Hun Lee, B. Brotman, 2005, The Journal of infectious diseases.

Drugs that target early stages of Onchocerca volvulus: A revisited means to facilitate the elimination goals for onchocerciasis

S. Lustigman, J. Sakanari, Christina A. Bulman, 2021, PLoS neglected tropical diseases.

Optimization of recombinant vaccinia-based ELISPOT assay.

M. Perkus, A. Prince, A. Talal, 2003, Journal of immunological methods.

Yeast-expressed recombinant protein of the receptor-binding domain in SARS-CoV spike protein with deglycosylated forms as a SARS vaccine candidate

Elissa M. Hudspeth, P. Hotez, Shibo Jiang, 2014, Human vaccines & immunotherapeutics.

Design, synthesis, and biological activities of closantel analogues: structural promiscuity and its impact on Onchocerca volvulus.

K. Janda, C. Gloeckner, F. Cho-Ngwa, 2011, Journal of medicinal chemistry.

Ligand binding properties of two Brugia malayi fatty acid and retinol (FAR) binding proteins and their vaccine efficacies against challenge infection in gerbils

P. Hotez, L. Lian, M. Bottazzi, 2018, PLoS neglected tropical diseases.

Exploiting the Polypharmacology of ß-Carbolines to Disrupt O. volvulus Molting.

K. Janda, Sacha Javor, S. Lustigman, 2015, ACS medicinal chemistry letters.

Discovery of New Broad-Spectrum Anti-Infectives for Eukaryotic Pathogens Using Bioorganometallic Chemistry

Robert W. Li, M. Mitreva, M. Moretto, 2023, bioRxiv.

in HLA-A 2 . 1-Transgenic Mice Recombinant HCV-Vaccinia Virus Infection Responses and Protection from Canarypox Virus Boosting Induces Immune by HCV DNA Priming-Recombinant Immunization ( HCV ) Polycistronic Genes or DNA Immunization with Hepatitis C Virus

M. Perkus, P. Pancholi, A. Prince, 2002 .

Adjuvanted Fusion Protein Vaccine Induces Durable Immunity to Onchocerca volvulus in Mice and Non-Human Primates

N. Petrovsky, D. Carter, M. Bottazzi, 2023, Vaccines.

Anti-Plasmodium falciparum invasion ligand antibodies in a low malaria transmission region, Loreto, Peru

D. Gamboa, J. Vinetz, S. Lustigman, 2012, Malaria Journal.

Discovery of New Broad-Spectrum Anti-Infectives for Eukaryotic Pathogens Using Bioorganometallic Chemistry.

M. Mitreva, S. Lustigman, J. Sakanari, 2023, Journal of medicinal chemistry.