Jessica S. Blackburn

发表

Improved Somatic Mutagenesis in Zebrafish Using Transcription Activator-Like Effector Nucleases (TALENs)

J. Keith Joung, Jeffry D. Sander, C. L. Ramirez, 2012, PloS one.

Selection-Free Zinc-Finger Nuclease Engineering by Context-Dependent Assembly (CoDA)

Feng Zhang, Drena Dobbs, Daniel F. Voytas, 2010, Nature Methods.

Long-read sequencing of the zebrafish genome reorganizes genomic architecture

Jessica S. Blackburn, J. Blackburn, Jinze Liu, 2021, bioRxiv.

Notch signaling expands a pre-malignant pool of T-cell acute lymphoblastic leukemia clones without affecting leukemia-propagating cell frequency

S. Ramaswamy, D. Neuberg, A. Look, 2012, Leukemia.

Single-cell transcriptional analysis of normal, aberrant, and malignant hematopoiesis in zebrafish

C. Ceol, R. Mylvaganam, R. Sadreyev, 2016, The Journal of experimental medicine.

TOX Regulates Growth, DNA Repair, and Genomic Instability in T-cell Acute Lymphoblastic Leukemia.

R. Young, A. Look, K. Stegmaier, 2017, Cancer discovery.

Optimized cell transplantation using adult rag2 mutant zebrafish

Y. Houvras, J. Berman, D. Langenau, 2014, Nature Methods.

Clonal evolution enhances leukemia-propagating cell frequency in T cell acute lymphoblastic leukemia through Akt/mTORC1 pathway activation.

Charles Lee, D. Langenau, K. Dobrinski, 2014, Cancer cell.

High-throughput cell transplantation establishes that tumor-initiating cells are abundant in zebrafish T-cell acute lymphoblastic leukemia.

L. Zon, D. Langenau, Yi Zhou, 2010, Blood.

Matrix metalloproteinase and G protein coupled receptors: co-conspirators in the pathogenesis of autoimmune disease and cancer.

C. Brinckerhoff, P. Burrage, Jessica S. Blackburn, 2009, Journal of autoimmunity.

In vivo imaging of tumor-propagating cells, regional tumor heterogeneity, and dynamic cell movements in embryonal rhabdomyosarcoma.

A. Rosenberg, D. Langenau, T. Mempel, 2012, Cancer cell.

Protein tyrosine phosphatase 4A3 (PTP4A3/PRL-3) drives migration and progression of T-cell acute lymphoblastic leukemia in vitro and in vivo

Jessica S. Blackburn, M. Wei, J. Blackburn, 2020, Oncogenesis.

Imaging tumour cell heterogeneity following cell transplantation into optically clear immune-deficient zebrafish

C. Bourque, A. Look, Y. Houvras, 2016, Nature Communications.

Zebrafish Cancer Avatars: A Translational Platform for Analyzing Tumor Heterogeneity and Predicting Patient Outcomes

Analiz Rodriguez, Jessica S. Blackburn, J. Blackburn, 2023, International journal of molecular sciences.

Generation of conditional Hoxc8 loss‐of‐function and Hoxc8→Hoxc9 replacement alleles in mice

Nima Ghitani, Jeh-Ping Liu, Jessica S. Blackburn, 2009, Genesis.

A Matrix Metalloproteinase-1/Protease Activated Receptor-1 signaling axis promotes melanoma invasion and metastasis

C. Brinckerhoff, C. I. Coon, Jessica S. Blackburn, 2009, Oncogene.

Matrix metalloproteinase-1 and thrombin differentially activate gene expression in endothelial cells via PAR-1 and promote angiogenesis.

C. Brinckerhoff, Jessica S. Blackburn, J. Blackburn, 2008, The American journal of pathology.

RNA interference inhibition of matrix metalloproteinase-1 prevents melanoma metastasis by reducing tumor collagenase activity and angiogenesis.

C. Brinckerhoff, C. I. Coon, C. Rhodes, 2007, Cancer research.

Optimization of human cancer cell xenograft into zebrafish larvae for anti-cancer drug screening

R. Sun, Jessica S. Blackburn, M. Wei, 2021 .

Targeting phosphatases of regenerating liver (PRLs) in cancer

K. Korotkov, Jessica S. Blackburn, M. Wei, 2018, Pharmacology & therapeutics.

Quantifying the Frequency of Tumor-propagating Cells Using Limiting Dilution Cell Transplantation in Syngeneic Zebrafish

D. Langenau, Jessica S. Blackburn, J. Blackburn, 2011, Journal of visualized experiments : JoVE.

A screen of FDA-approved drugs identifies inhibitors of protein tyrosine phosphatase 4A3 (PTP4A3 or PRL-3)

Jessica S. Blackburn, Donghan Lee, J. Blackburn, 2020, Scientific Reports.

Zebrafish as a model to assess cancer heterogeneity, progression and relapse

D. Langenau, Jessica S. Blackburn, J. Blackburn, 2014, Disease Models & Mechanisms.

Zebrafish as a model to assess cancer heterogeneity, progression and relapse

D. Langenau, Jessica S. Blackburn, J. Blackburn, 2014, Disease Models & Mechanisms.

Zebrafish Drug Screening Identifies Erlotinib as an Inhibitor of Wnt/β-Catenin Signaling and Self-Renewal in T-cell Acute Lymphoblastic Leukemia

Wen Zhang, Chunming Liu, Jessica S. Blackburn, 2023, bioRxiv.

Protocol for rapid assessment of the efficacy of novel Wnt inhibitors using zebrafish models

Chunming Liu, Jessica S. Blackburn, J. Blackburn, 2021, STAR protocols.

Epigenetic Regulation of Wnt Signaling by Carboxamide-Substituted Benzhydryl Amines that Function as Histone Demethylase Inhibitors

C. Zhan, D. Watt, Tianxin Yu, 2020, iScience.

Drug Screening of Primary Patient Derived Tumor Xenografts in Zebrafish.

Jessica S. Blackburn, J. Blackburn, M. Haney, 2020, Journal of visualized experiments : JoVE.

A series of N-terminal epitope tagged Hdh knock-in alleles expressing normal and mutant huntingtin: their application to understanding the effect of increasing the length of normal huntingtin’s polyglutamine stretch on CAG140 mouse model pathogenesis

Nima Ghitani, S. Zeitlin, Jeh-Ping Liu, 2012, Molecular Brain.

In vivo imaging defines vascular interplay in the development of lymphocytic leukemia in zebrafish models

Jessica S. Blackburn, J. Blackburn, S. Revskoy, 2019, bioRxiv.

Development and characterization of nanobodies that specifically target the oncogenic Phosphatase of Regenerating Liver-3 (PRL-3) and impact its interaction with a known binding partner, CNNM3

L. Hersh, K. Korotkov, Jessica S. Blackburn, 2023, PloS one.

Development and characterization of nanobodies specifically targeting the oncogenic Phosphatase of Regenerating Liver-3 (PRL-3)

L. Hersh, K. Korotkov, Jessica S. Blackburn, 2022, bioRxiv.

Development and characterization of nanobodies specifically targeting the oncogenic Phosphatase of Regenerating Liver-3 (PRL-3)

K., L. Hersh, K. Korotkov, 2020, bioRxiv.

TOX Regulates Growth, DNA Repair, and Genomic Instability in T-cell Acute Lymphoblastic Leukemia.

A. Look, K. Stegmaier, K. Shah, 2017, Cancer discovery.

Biological Investigations of Ru(II) Complexes With Diverse β-diketone Ligands.

S. Parkin, D. Havrylyuk, Jessica S. Blackburn, 2021, European journal of inorganic chemistry.

Triarylphosphine-Coordinated Bipyridyl Ru(II) Complexes Induce Mitochondrial Dysfunction.

S. Parkin, J. Unrine, Viral Oza, 2023, Inorganic chemistry.

Wild‐type versus mutant MMP‐8 in melanoma: ‘When you come to a fork in the road, take it’ *

C. Brinckerhoff, Jessica S. Blackburn, J. Blackburn, 2009, Pigment cell & melanoma research.

Matrix metalloproteinase-1 and thrombin differentially activate gene expression in endothelial cells via PAR-1 and promote angiogenesis.

C. Brinckerhoff, Jessica S. Blackburn, 2008, The American journal of pathology.

PRL3 enhances T cell acute lymphoblastic leukemia growth through suppressing T cell signaling pathways and apoptosis

F. Speleman, S. Iyer, W. Haas, 2020, Leukemia.

Phosphatase and Pseudo-Phosphatase Functions of Phosphatase of Regenerating Liver 3 (PRL-3) Are Insensitive to Divalent Metals In Vitro

Jessica S. Blackburn, Jeffery T. Jolly, Ty C. Cheatham, 2023, ACS omega.

In vivo imaging of tumor-propagating cells, regional tumor heterogeneity, and dynamic cell movements in embryonal rhabdomyosarcoma.

A. Rosenberg, D. Langenau, T. Mempel, 2012, Cancer cell.

Nanopore sequencing of clonal IGH rearrangements in cell-free DNA as a biomarker for acute lymphoblastic leukemia

Thomas C. Badgett, Jessica S. Blackburn, J. Blackburn, 2022, Frontiers in Oncology.

Nanopore sequencing methods detect cell-free DNA associated with MRD and CNS infiltration in pediatric Acute Lymphoblastic Leukemia

Thomas C. Badgett, Jessica S. Blackburn, J. Blackburn, 2021 .

Avobenzone incorporation in a diverse range of Ru(II) scaffolds produces potent potential antineoplastic agents.

D. Kim, D. Havrylyuk, Jessica S. Blackburn, 2020, Dalton transactions.

Collagenase Activity and Angiogenesis Prevents Melanoma Metastasis by Reducing Tumor RNA Interference Inhibition of Matrix Metalloproteinase-1

C. Brinckerhoff, C. I. Coon, C. Rhodes, 2007 .

Semisynthetic aurones inhibit tubulin polymerization at the colchicine-binding site and repress PC-3 tumor xenografts in nude mice and myc-induced T-ALL in zebrafish

J. Chen, L. Dwoskin, C. Zhan, 2019, Scientific Reports.