M. Sasaki

发表

Total synthesis of (+)-neopeltolide.

H. Fuwa, Shinya Naito, T. Goto, 2008, Angewandte Chemie.

Fluorescence-labeled neopeltolide derivatives for subcellular localization imaging.

Shinsuke Niwa, A. Sugimoto, H. Fuwa, 2019, Organic & biomolecular chemistry.

Synthesis and biological evaluation of (+)-neopeltolide analogues: importance of the oxazole-containing side chain.

H. Fuwa, M. Sasaki, T. Noguchi, 2014, Bioorganic & medicinal chemistry letters.

Total synthesis and biological evaluation of (+)-neopeltolide and its analogues.

Asami Saito, M. Yotsu-Yamashita, K. Konoki, 2009, Chemistry.

Total synthesis and biological assessment of (-)-exiguolide and analogues.

H. Kubo, T. Yamori, H. Fuwa, 2011, Chemistry.

Exploiting Ruthenium Carbene-Catalyzed Reactions in Total Synthesis of Marine Oxacyclic Natural Products

H. Fuwa, M. Sasaki, 2016 .

Stereoselective synthesis of 2,6-cis-substituted tetrahydropyrans: Brønsted acid-catalyzed intramolecular oxa-conjugate cyclization of α,β-unsaturated ester surrogates.

H. Fuwa, M. Sasaki, Naoki Ichinokawa, 2012, The Journal of organic chemistry.

A concise total synthesis of (+)-neopeltolide.

Asami Saito, H. Fuwa, M. Sasaki, 2010, Angewandte Chemie.

Synthesis and Biological Evaluation of Aspergillide A/Neopeltolide Chimeras

H. Fuwa, M. Sasaki, M. Kawakami, 2013 .

Total Synthesis of (+)‐Neopeltolide.

H. Fuwa, Shinya Naito, T. Goto, 2008 .

A General Method for Convergent Synthesis of Polycyclic Ethers Based on Suzuki Cross-Coupling: Concise Synthesis of the ABCD Ring System of Ciguatoxin

K. Tachibana, H. Fuwa, M. Sasaki, 1999 .

Total synthesis of gambierol.

M. Satake, K. Tachibana, H. Fuwa, 2002, Organic letters.

Convergent total synthesis of gymnocin-A and evaluation of synthetic analogues.

C. Tsukano, M. Sasaki, Makoto Ebine, 2005, Journal of the American Chemical Society.

Concise and Short Synthesis of Functionalized 5,6-Dihydropyridin-2-ones by Means of Palladium(0)-Catalyzed Cross-Coupling of Ketene Aminal Phosphates

T. Iwatsubo, T. Tomita, H. Fuwa, 2006 .

Total synthesis, structure revision, and absolute configuration of (-)-brevenal.

D. Baden, A. Bourdelais, H. Fuwa, 2006, Journal of the American Chemical Society.

A new method for the generation of indole-2,3-quinodimethanes and 2-(N-alkoxycarbonylamino)-1,3-dienes. Intramolecular Heck/Diels–Alder cycloaddition cascade starting from acyclic α-phosphono enecarbamates

H. Fuwa, M. Sasaki, 2007 .

Strategies for the synthesis of 2-substituted indoles and indolines starting from acyclic alpha-phosphoryloxy enecarbamates.

H. Fuwa, M. Sasaki, 2007, Organic letters.

An efficient method for the synthesis of enol ethers and enecarbamates. Total syntheses of isoindolobenzazepine alkaloids, lennoxamine and chilenine.

H. Fuwa, M. Sasaki, 2007, Organic & biomolecular chemistry.

Pharmacological activity of C10-substituted analogs of the high-affinity kainate receptor agonist dysiherbaine

Pekka A. Postila, R. Sakai, O. Pentikäinen, 2010, Neuropharmacology.

Transition metal tetrachloroaluminate catalysts for probe reactions simulating petroleum resids upgrading

Chunshan Song, M. Sasaki, M. Plummer, 2000 .

2-Oxo-1,2-ethylenedioxy group as a linker for solution-, liquid-, and solid-phase syntheses to discover drug-like small molecules

M. Oikawa, M. Sasaki, Y. Takeda, 2005 .

Alkoxyacetyl (AAc) group as a useful linker for organic synthesis on poly(ethylene glycol) support

M. Oikawa, M. Sasaki, M. Ikoma, 2004 .

Simple formylacetal (CH2) as a novel linker for saccharide synthesis on soluble-polymer support

S. Kusumoto, Tatsushi Tanaka, M. Oikawa, 2004 .

Effect of carbon chain length in acyl coenzyme A on the efficiency of enzymatic transformation of okadaic acid to 7-O-acyl okadaic acid.

M. Yotsu-Yamashita, K. Konoki, H. Fuwa, 2016, Bioorganic & medicinal chemistry letters.

Concise synthesis of the C15-C38 fragment of okadaic acid: application of the Suzuki-Miyaura reaction to spiroacetal synthesis.

H. Fuwa, M. Sasaki, Keita Sakamoto, 2015, Organic letters.

Proteomic analysis reveals multiple patterns of response in cells exposed to a toxin mixture.

T. Yasumoto, G. Ronzitti, G. Rossini, 2009, Chemical research in toxicology.

A convergent synthesis of the C1-C16 segment of goniodomin A via palladium-catalyzed organostannane-thioester coupling.

H. Fuwa, M. Sasaki, Y. Takeda, 2011, Organic letters.

Calcium oscillations induced by gambierol in cerebellar granule cells

C. Vale, M. Vieytes, L. Botana, 2010, Journal of cellular biochemistry.

SIRVVD model-based verification of the effect of first and second doses of COVID-19/SARS-CoV-2 vaccination in Japan.

J. Toyotani, Y. Gon, M. Sasaki, 2021, Mathematical biosciences and engineering : MBE.

Total Synthesis of (-)-Enigmazole A.

H. Fuwa, M. Sasaki, K. Sakurai, 2018, Angewandte Chemie.

Gambierol Blocks a K+ Current Fraction without Affecting Catecholamine Release in Rat Fetal Adrenomedullary Cultured Chromaffin Cells

J. Molgó, E. Benoit, H. Fuwa, 2022, Toxins.

Synthetic studies on goniodomin A: convergent assembly of the C15–C36 segment via palladium-catalyzed organostannane–thioester coupling

H. Fuwa, M. Sasaki, Tomoyuki Saito, 2011 .

Characteristics of Nonylphenol Polyethoxylate-Degrading Bacteria Isolated from Coastal Sediments

K. Hayakawa, M. Sasaki, T. Maeda, 2005 .

Degradation of Nonylphenol polyethoxylate (NPEOpoly) by Mixed Marine Bacterial Populations

M. Sasaki, B. You, T. Maeda, 2002 .

Bacterial Enzymes Catalyzing the Synthesis of 1,8-Dihydroxynaphthalene, a Key Precursor of Dihydroxynaphthalene Melanin, from Sorangium cellulosum

Seung-Young Kim, N. Funa, M. Sasaki, 2018, Applied and Environmental Microbiology.

Evaluation of gambierol and its analogs for their inhibition of human Kv1.2 and cytotoxicity.

M. Yotsu-Yamashita, K. Konoki, H. Fuwa, 2015, Bioorganic & medicinal chemistry letters.

Potassium currents inhibition by gambierol analogs prevents human T lymphocyte activation

C. Vale, L. Botana, J. Rubiolo, 2014, Archives of Toxicology.

A CONCISE SYNTHESIS OF THE AB-RING FRAGMENT OF (−)-GAMBIEROL

H. Fuwa, M. Sasaki, K. Hirota, 2012 .

Comparative cytotoxicity of gambierol versus other marine neurotoxins.

B. Espiña, M. Vieytes, L. Botana, 2011, Chemical research in toxicology.

The marine polyether gambierol enhances muscle contraction and blocks a transient K(+) current in skeletal muscle cells.

L. Botana, M. C. Louzao, E. Girard, 2010, Toxicon : official journal of the International Society on Toxinology.

The Sodium Channel of Human Excitable Cells is a Target for Gambierol

M. Vieytes, L. Botana, M. C. Louzao, 2006, Cellular Physiology and Biochemistry.

Pathological effects on mice by gambierol, possibly one of the ciguatera toxins.

M. Satake, K. Tachibana, K. Toshimori, 2003, Toxicon : official journal of the International Society on Toxinology.

Total synthesis of gambierol.

M. Satake, K. Tachibana, H. Fuwa, 2002, Organic letters.

Effect of gambierol and its tetracyclic and heptacyclic analogues in cultured cerebellar neurons: a structure-activity relationships study.

C. Vale, M. Vieytes, L. Botana, 2012, Chemical research in toxicology.

Diverted total synthesis and biological evaluation of gambierol analogues: elucidation of crucial structural elements for potent toxicity.

M. Satake, K. Tachibana, C. Tsukano, 2004, Chemistry.

Total synthesis of isoindolobenzazepine alkaloids, lennoxamine and chilenine, based on palladium-catalyzed reduction of alkenyl phosphates

H. Fuwa, M. Sasaki, 2008 .

Glycosylation reaction under high pressure

M. Sasaki, Y. Ishigami, Masahiko Yasumoto, 1990 .

Skeletal diversity by allylation/RCM on Ugi four-component coupling reaction products

M. Oikawa, Shinya Naito, M. Sasaki, 2006 .

Gambierol enhances evoked quantal transmitter release and blocks a potassium current in motor nerve terminals of the mouse neuromuscular junction

D. Servent, M. C. Louzao, J. Molgó, 2022 .

Highly efficient synthesis of medium-sized lactones via oxidative lactonization: concise total synthesis of isolaurepan.

H. Fuwa, M. Sasaki, Makoto Ebine, 2010, Organic & biomolecular chemistry.

A strategy for the synthesis of 2,3-disubstituted indoles starting from N-(o-halophenyl)allenamides.

H. Fuwa, M. Sasaki, 2007, Organic & biomolecular chemistry.

Total Synthesis and Complete Stereostructure of a Marine Macrolide Glycoside, (-)-Lyngbyaloside B.

Asami Saito, Naoya Yamagata, H. Fuwa, 2016, Chemistry.

Total synthesis and biological evaluation of (-)-exiguolide analogues: importance of the macrocyclic backbone.

H. Kubo, H. Fuwa, M. Sasaki, 2013, Organic & biomolecular chemistry.

Total synthesis of 13-demethyllyngbyaloside B.

Asami Saito, Naoya Yamagata, H. Fuwa, 2013, Organic letters.

Synthetic Studies toward Ciguatoxin. Stereocontrolled Construction of the KLM Ring Fragment

K. Tachibana, M. Inoue, M. Sasaki, 1994 .

Regioselective Domino Metathesis of 7-Oxanorbornenes and Its Application to the Synthesis of Biologically Active Glutamate Analogues.

R. Sakai, K. Shimamoto, M. Oikawa, 2008, European journal of organic chemistry.

Regioselective Domino Metathesis of Unsymmetrical 7-Oxanorbornenes with Electron-Rich Vinyl Acetate toward Biologically Active Glutamate Analogues.

R. Sakai, K. Shimamoto, M. Oikawa, 2009, European journal of organic chemistry.

Stereoselective Synthesis of the C1–C16 Fragment of Goniodomin A

H. Fuwa, M. Sasaki, M. Nakajima, 2012 .

Tandem catalysis in domino olefin cross-metathesis/intramolecular oxa-conjugate cyclization: concise synthesis of 2,6-cis-substituted tetrahydropyran derivatives.

H. Fuwa, M. Sasaki, T. Noguchi, 2012, Organic & biomolecular chemistry.

Enzymatic synthesis of useful alkyl β-glucosides

T. Fujii, H. Shinoyama, M. Sasaki, 1991 .

Synthesis and stereochemical confirmation of the cis-fused L/M and N/O ring systems of maitotoxin

K. Tachibana, M. Murata, M. Sasaki, 1994 .

Synthesis of bruceantin skeleton

M. Sasaki, T. Konosu, T. Murae, 1986 .

Novel Analogs and Stereoisomers of the Marine Toxin Neodysiherbaine with Specificity for Kainate Receptors

Pekka A. Postila, R. Sakai, O. Pentikäinen, 2008, Journal of Pharmacology and Experimental Therapeutics.

A new method for the generation of indole-2,3-quinodimethanes from allenamides

H. Fuwa, M. Sasaki, Makoto Ebine, 2008 .

Simultaneous accumulation of both skeletal and appendage-based diversities on tandem Ugi/Diels–Alder products

M. Oikawa, M. Sasaki, M. Ikoma, 2005 .

Parallel synthesis of tandem Ugi/Diels–Alder reaction products on a soluble polymer support directed toward split-pool realization of a small molecule library

M. Oikawa, M. Sasaki, M. Ikoma, 2005 .

Stereodivergent Synthesis and Configurational Assignment of the C1-C15 Segment of Amphirionin-5.

M. Tsuda, Sota Sato, M. Sasaki, 2016, The Journal of organic chemistry.

Synthetic Studies on Amphirionin-5: Stereochemical Assignment/Reassignment of the C1-C9 Portion through Stereodivergent Synthesis.

M. Sasaki, Moemi Kanto, 2016, Organic letters.

Studies toward the Total Synthesis of Amphidinolide N: Stereocontrolled Synthesis of the C13–C29 Segment

Y. Kawashima, H. Fuwa, M. Sasaki, 2015 .

A convergent synthesis of the trans-fused hexahydrooxonine ring system and reproduction of conformational behavior shown by ring F of ciguatoxin

K. Tachibana, M. Inoue, M. Sasaki, 1999 .

A new strategy for the synthesis of substituted dihydropyrones and tetrahydropyrones via palladium-catalyzed coupling of thioesters

H. Fuwa, M. Sasaki, K. Mizunuma, 2011 .

Total Synthesis of Polycyclic Ether Natural Products Based on Suzuki-Miyaura Cross-Coupling

H. Fuwa, M. Sasaki, 2004 .

BIGINELLI REACTION USING ACETOACETAMIDE DERIVATIVES

M. Sasaki, T. Chiba, Tetsuzo Kato, 1981 .

Synthetic Studies on Dragmacidin D: Synthesis and Assembly of Three Fragments Towards an Advanced Intermediate

M. Oikawa, M. Sasaki, M. Ikoma, 2011 .

Synthesis and domino metathesis of functionalized 7-oxanorbornene analogs toward cis-fused heterocycles

M. Oikawa, M. Sasaki, M. Ikoma, 2008 .

Stereoselective synthesis of substituted tetrahydropyrans via domino olefin cross-metathesis/intramolecular oxa-conjugate cyclization.

H. Fuwa, M. Sasaki, Kenkichi Noto, 2010, Organic letters.

Divergent synthesis of multifunctional molecular probes to elucidate the enzyme specificity of dipeptidic gamma-secretase inhibitors.

T. Iwatsubo, T. Kan, T. Tomita, 2007, ACS chemical biology.

Chemospecific Allylation and Domino Metathesis of 7‐Oxanorbornenes for Skeletal and Appendage Diversity

M. Oikawa, M. Sasaki, M. Ikoma, 2008 .

A three-component approach to isoquinoline derivatives by cycloaddition/Heck reaction sequence

D. Hashizume, H. Koshino, M. Oikawa, 2007 .

Total Synthesis of Polycavernosides A and B, Two Lethal Toxins from Red Alga.

M. Yotsu-Yamashita, Y. Kasai, Y. Kawashima, 2017, The Journal of organic chemistry.

Total synthesis and complete structural assignment of gambieric acid A, a large polycyclic ether marine natural product.

H. Fuwa, M. Sasaki, 2014, Chemical record.

Total synthesis and structure revision of didemnaketal B.

H. Fuwa, M. Sasaki, T. Muto, 2014, Chemistry.

Total synthesis of (-)-polycavernoside A: Suzuki-Miyaura coupling approach.

Y. Kasai, M. Sasaki, Takanori Ito, 2012, Organic letters.

Studies toward the total synthesis of gambieric acids, potent antifungal polycyclic ethers: convergent synthesis of a fully elaborated GHIJ-ring fragment

H. Fuwa, M. Sasaki, Koichi Tsubone, 2011 .

Studies toward the total synthesis of gambieric acids: convergent synthesis of the GHIJ-ring fragment having a side chain

H. Fuwa, M. Sasaki, Koichi Tsubone, 2011 .

Convergent synthesis of the ABCDE ring fragment of ciguatoxins

H. Takakura, K. Tachibana, H. Fuwa, 2004 .

Synthetic studies on dragmacidin D: synthesis of the left-hand fragment

M. Oikawa, M. Sasaki, M. Ikoma, 2008 .

Studies toward the total synthesis of azaspiracids: synthesis of the FGHI ring domain

M. Oikawa, M. Sasaki, Yuko Iwamuro, 2003 .

Convergent synthesis of an HIJK ring model of ciguatoxin via Suzuki cross-coupling reaction

K. Tachibana, H. Fuwa, M. Sasaki, 2000 .

Toward a total synthesis of amphidinolide N: convergent synthesis of the C1–C13 segment

A. Toyoshima, M. Sasaki, 2016 .

A general strategy for the convergent synthesis of fused polycyclic ethers via B-alkyl Suzuki coupling: synthesis of the ABCD ring fragment of ciguatoxins

K. Tachibana, M. Ishikawa, H. Fuwa, 2002 .

Synthetic studies on a marine polyether toxin, gambierol: stereoselective synthesis of the FGH ring system via B-alkyl Suzuki coupling

K. Tachibana, H. Fuwa, M. Sasaki, 2000 .

Total synthesis and complete stereostructure of gambieric acid A.

H. Fuwa, M. Sasaki, Keisuke Hashizume, 2012, Journal of the American Chemical Society.

Toward the total synthesis of goniodomin A, an actin-targeting marine polyether macrolide: convergent synthesis of the C15-C36 segment.

H. Fuwa, M. Sasaki, Tomoyuki Saito, 2009, Organic letters.

Toward the Total Synthesis of Amphidinolide N: Synthesis of the C8-C29 Fragment.

A. Toyoshima, Y. Kawashima, H. Fuwa, 2016, Organic letters.

Synthesis of the CDE/FG ring models of prymnesins: reassignment of the relative configuration of the E/F ring juncture.

M. Satake, T. Yasumoto, H. Takakura, 2004, Organic letters.

Synthesis of 2-substituted indoles and indolines via Suzuki-Miyaura coupling/5-endo-trig cyclization strategies.

H. Fuwa, M. Sasaki, 2009, The Journal of organic chemistry.

Synthesis of skeleton of antitumor quassinoid

M. Sasaki, N. Tanaka, Y. Usuki, 1988 .

The Complete Structure of Maitotoxin, Part I: Configuration of the C1C14 Side Chain

N. Matsumori, T. Yasumoto, K. Tachibana, 1996 .

The Complete Structure of Maitotoxin, Part II: Configuration of the C135 ? C142 Side Chain and Absolute Configuration of the Entire Molecule

N. Matsumori, T. Yasumoto, K. Tachibana, 1996 .

Total synthesis of (-)-brevenal: a streamlined strategy for practical synthesis of polycyclic ethers.

H. Fuwa, M. Sasaki, Makoto Ebine, 2011, Chemistry.

Convergent strategies for the total synthesis of polycyclic ether marine metabolites.

H. Fuwa, M. Sasaki, 2008, Natural product reports.

Stereocontrolled Synthesis of the JKLM Ring Fragment of Ciguatoxin

K. Tachibana, M. Inoue, M. Sasaki, 1999 .

Synthesis of open-chain C21-C40 fragment of azaspiracid-1

M. Oikawa, M. Sasaki, Taizo Iwayama, 2009 .

An Efficient Synthesis of 2,6-Disubstituted 2,3-Dihydro-4H-pyran-4-ones via Sonogashira Coupling of p-Toluenethiol Esters

H. Fuwa, M. Sasaki, S. Matsukida, 2010 .

Synthetic study of azaspiracid-1: synthesis of the EFGHI-ring fragment.

M. Oikawa, M. Sasaki, T. Uehara, 2006, Organic letters.

Convergent and Scalable Synthesis of the ABCDE-Ring Fragment of Caribbean Ciguatoxin C-CTX-1.

M. Sasaki, Atsushi Umehara, Miku Seida, 2022, The Journal of organic chemistry.

Total synthesis and biological evaluation of (+)-gambieric acid A and its analogues.

M. Yotsu-Yamashita, H. Fuwa, M. Sasaki, 2013, Chemistry.

Convergent synthesis of the BCDEFGHIJ-ring polyether core of gambieric acids, potent antifungal polycyclic ethers

Kazushi Sato, M. Sasaki, 2007 .

Studies toward the total synthesis of gambieric acids A and C: convergent assembly of the nonacyclic polyether skeleton.

Kazushi Sato, M. Sasaki, 2007, Angewandte Chemie.

Concise synthesis of the A/BCD-ring fragment of gambieric acid A

H. Fuwa, M. Sasaki, Ryouko Fukazawa, 2014, Front. Chem..

Novel gamma-secretase inhibitors discovered by library screening of in-house synthetic natural product intermediates.

Yasuko Takahashi, Takeshi Iwatsubo, Makoto Sasaki, 2006, Bioorganic & medicinal chemistry letters.

Recent Applications of the Suzuki-Miyaura Cross-coupling to Complex Polycyclic Ether Synthesis

H. Fuwa, M. Sasaki, Makoto Ebine, 2011 .

Development and Application of a Convergent Strategy for the Total Synthesis of Polycyclic Ether Natural Products

M. Sasaki, 2007 .

Synthesis and biological evaluation of gambierol analogues.

M. Satake, H. Fuwa, M. Sasaki, 2003, Bioorganic & medicinal chemistry letters.

Total synthesis of (-)-gambierol.

K. Tachibana, H. Fuwa, M. Sasaki, 2002, Journal of the American Chemical Society.

Synthetic studies toward gambierol. Convergent synthesis of the octacyclic polyether core.

K. Tachibana, H. Fuwa, M. Sasaki, 2001, Organic letters.

Synthetic Studies on Polyether Natural Products : New Synthetic Methods for Construction of Medium-Sized Cyclic Ethers and Convergent Coupling of Polyether Fragments

M. Inoue, M. Sasaki, 2001 .

Recent Advances in Total Synthesis of Marine Polycyclic Ethers

M. Sasaki, 2008 .

Synthetic Studies on Ciguatoxin: A Highly Convergent Synthesis of the GHIJKLM Ring System Based on B-Alkyl Suzuki Coupling.

H. Takakura, K. Tachibana, M. Sasaki, 2001, Angewandte Chemie.

Construction of fused oxonene ring and reproduction of conformational behavior shown by ring F of ciguatoxin

K. Tachibana, M. Inoue, M. Sasaki, 1997 .

Stereoselective synthesis of a KLM ring model of ciguatoxin : confirmation of the C54 stereochemistry

A. Hasegawa, K. Tachibana, M. Sasaki, 1993 .

Synthesis of the JK/LM-ring model of prymnesins, potent hemolytic and ichthyotoxic polycyclic ethers isolated from the red tide alga Prymnesium parvum: confirmation of the relative configuration of the K/L-ring juncture

Ryuichi Watanabe, M. Satake, H. Fuwa, 2006 .

Progress toward the Total Synthesis of Goniodomin A: Stereocontrolled, Convergent Synthesis of the C12-C36 Fragment.

Y. Kawashima, H. Fuwa, M. Sasaki, 2016, The Journal of organic chemistry.

Studies toward the total synthesis of gymnocin A, a cytotoxic polyether: a highly convergent entry to the F-N ring fragment.

K. Tachibana, C. Tsukano, M. Sasaki, 2002, Organic letters.

Synthesis and stereochemical confirmation of the HI/JK ring system of prymnesins, potent hemolytic and ichthyotoxic glycoside toxins isolated from the red tide alga

Takeshi Shida, K. Tachibana, M. Sasaki, 2001 .

Stereochemical assignment of the C35-C39 Acyclic linkage in maitotoxin: completion of stereochemical determination of C15-C134

N. Matsumori, T. Yasumoto, K. Tachibana, 1995 .

Total synthesis of (−)-dysiherbaine, a novel neuroexcitotoxic amino acid

R. Sakai, K. Tachibana, M. Sasaki, 2000 .

Studies toward the total synthesis of gambieric acids, potent antifungal polycyclic ethers: convergent synthesis of the CDEFG-ring system.

Kazushi Sato, M. Sasaki, 2005, Organic letters.

Synthesis of the FGH ring fragment of ciguatoxin

K. Tachibana, M. Sasaki, Tetsuji Noguchi, 1999 .

Convergent and stereoselective method for synthesis of O-linked oxepane ring system by intramolecular radical cyclization

K. Tachibana, M. Inoue, M. Sasaki, 1998 .

Synthetic Studies on Ciguatoxin: A Convergent Strategy for Construction of the F-M Ring Framework.

K. Tachibana, M. Inoue, M. Sasaki, 1998, Angewandte Chemie.

Convergent assembly of the spiroacetal subunit of didemnaketal B.

H. Fuwa, M. Sasaki, Sayaka Noji, 2010, Organic letters.

Total Synthesis of Dysiherbaine.

R. Sakai, M. Oikawa, M. Sasaki, 2007 .

Total synthesis of the proposed structure of didemnaketal B.

H. Fuwa, M. Sasaki, K. Sekine, 2013, Organic letters.

Asymmetric Synthesis and in vivo Biological Inactivity of the Right‐Hand Terpenoid Fragment of Terpendole E

M. Oikawa, M. Sasaki, R. Hashimoto, 2011 .

A concise total synthesis of (±)-centrolobine

H. Fuwa, M. Sasaki, Kenkichi Noto, 2010 .

Concise synthesis and biological assessment of (+)-neopeltolide and a 16-member stereoisomer library of 8,9-dehydroneopeltolide: identification of pharmacophoric elements.

M. Yotsu-Yamashita, K. Konoki, H. Fuwa, 2013, Chemistry.

Adducts of acetylene and dimethylacetylenedicarboxylate at sulfurs in sulfur-bridged incomplete cubane-type tungsten clusters.

M. Sasaki, T. Shibahara, Yasuhiro Ide, 2004, Inorganic Chemistry.

Rapid and efficient synthesis of dysiherbaine and analogues to explore structure-activity relationships.

R. Sakai, K. Shimamoto, M. Oikawa, 2008, The Journal of organic chemistry.

Studies toward the Total Synthesis of Caribbean Ciguatoxin C-CTX-1: Synthesis of the LMN-Ring Fragment through Reductive Olefin Cross-Coupling.

M. Sasaki, Kotaro Iwasaki, Keisuke Arai, 2018, Organic letters.

A unified total synthesis of aspergillides A and B.

H. Fuwa, M. Sasaki, H. Yamaguchi, 2010, Organic letters.

Synthesis, structure, and oxidation of 3,4-dihydro-1,2,5-benzotrithiepins†

S. Ogawa, M. Sasaki, Y. Kawai, 1995 .

Stereoselective synthesis of medium-sized cyclic ethers: application of C-glycosylation chemistry to seven- to nine-membered lactone-derived thioacetals and their sulfone counterparts.

H. Fuwa, M. Sasaki, Yuto Suga, 2014, The Journal of organic chemistry.

Diastereoselective Ring-Closing Metathesis as a Means to Construct Medium-Sized Cyclic Ethers: Application to the Synthesis of a Photoactivatable Gambierol Derivative.

M. Yotsu-Yamashita, K. Konoki, H. Fuwa, 2016, The Journal of organic chemistry.

Physical Properties of Nematic Tolans

H. Takatsu, M. Sasaki, K. Takeuchi, 1986 .

Synthesis and Some Properties of 3-Fluoro-4-Cyanophenyl 4′-n-alkylbenzoates

H. Takatsu, M. Sasaki, K. Takeuchi, 1984 .

Design and synthesis of skeletal analogues of gambierol: attenuation of amyloid-β and tau pathology with voltage-gated potassium channel and N-methyl-D-aspartate receptor implications.

F. LaFerla, C. Vale, M. Vieytes, 2012, Journal of the American Chemical Society.

Total synthesis, stereochemical reassignment, and biological evaluation of (-)-lyngbyaloside B.

Naoya Yamagata, H. Fuwa, M. Sasaki, 2015, Angewandte Chemie.

Inhibition of Maitotoxin‐Induced Ca2+ Influx in Rat Glioma C6 Cells by Brevetoxins and Synthetic Fragments of Maitotoxin

K. Konoki, K. Tachibana, M. Murata, 1998, Journal of neurochemistry.

Long-range carbon-proton coupling constants for stereochemical assignment of acyclic structures in natural products: Configuration of the C5C9 portion of maitotoxin

N. Matsumori, M. Satake, T. Yasumoto, 1996 .

A highly efficient synthesis of tri-O-acyl-α-D-glucopyranose 1,2-(orthoesters) under high pressure

M. Sasaki, Y. Ishigami, Masahiko Yasumoto, 1990 .

An efficient and stereocontrolled synthesis of the nephritogenoside core structure

H. Nakanishi, K. Tachibana, M. Sasaki, 1991 .

Solvent and Pressure Dependence of the Energy Profile for the Thermal Fading of a Merocyanine Formed from a Spironaphthoxazine

Toru Takahashi, T. Asano, M. Sasaki, 2001 .

Dynamic solvent effects on the fading of a merocyanine formed from a spironaphthoxazine. A case of a strong coupling between chemical and medium coordinate

Toru Takahashi, T. Asano, M. Sasaki, 2004 .

Concise synthesis of the C15–C38 fragment of okadaic acid, a specific inhibitor of protein phosphatases 1 and 2A

H. Fuwa, M. Sasaki, Keita Sakamoto, 2015 .

Synthetic studies on gambieric acids, potent antifungal polycyclic ether natural products: reassignment of the absolute configuration of the nonacyclic polyether core by NMR analysis of model compounds.

H. Fuwa, T. Goto, M. Sasaki, 2009, The Journal of organic chemistry.

Stereoselective synthesis of the AB-ring fragment of gambieric acid A

Kazushi Sato, H. Fuwa, M. Sasaki, 2007 .

Progress toward the total synthesis of ciguatoxins: a convergent synthesis of the FGHIJKLM ring fragment.

H. Takakura, K. Tachibana, M. Sasaki, 2002, Organic letters.

Total synthesis and biological evaluation of neodysiherbaine A and analogues.

R. Sakai, K. Shimamoto, M. Oikawa, 2006, The Journal of organic chemistry.

Isolation, structure determination, and synthesis of neodysiherbaine A, a new excitatory amino acid from a marine sponge.

R. Sakai, A. Yano, K. Shimamoto, 2001, Organic letters.

5'-Nuclease PCR Assay of Gliding Bacteria that Kill Skeletonema costatum in Seawater

M. Sasaki, T. Maeda, M. Furushita, 2003 .

Hybridization Independent Increase of Fluorescence in a 5' Nuclease PCR Assay

M. Sasaki, B. You, T. Maeda, 2001 .

A formal synthesis of bruceantin

M. Sasaki, T. Murae, 1989 .

Programmed Cell Death Induced by (−)-8,9-Dehydroneopeltolide in Human Promyelocytic Leukemia HL-60 Cells under Energy Stress Conditions

H. Fuwa, M. Sasaki, M. Sato, 2014, Marine drugs.

Lantibiotic Transporter Requires Cooperative Functioning of the Peptidase Domain and the ATP Binding Domain*

J. Nakayama, T. Zendo, K. Sonomoto, 2011, The Journal of Biological Chemistry.

Determination of Binding Site Residues Responsible for the Subunit Selectivity of Novel Marine-Derived Compounds on Kainate Receptors

R. Sakai, Mark S. Johnson, L. Settimo, 2006, Molecular Pharmacology.

Dysiherbaine: A New Generation of Excitatory Amino Acids of Marine Origin

R. Sakai, K. Shimamoto, G. Swanson, 2006 .

Divergent Pharmacological Activity of Novel Marine-Derived Excitatory Amino Acids on Glutamate Receptors

R. Sakai, Mark S. Johnson, L. Settimo, 2005, Journal of Pharmacology and Experimental Therapeutics.

Effect of ciguatoxin 3C on voltage-gated Na+ and K+ currents in mouse taste cells.

T. Yasumoto, G. Rossini, M. Inoue, 2006, Chemical senses.

Cytotoxicity of goniodomin A and B in non contractile cells.

B. Espiña, M. Vieytes, L. Botana, 2016, Toxicology letters.

Structure–activity relationship studies of gymnocin-A

C. Tsukano, M. Sasaki, 2006 .

Suppression of colon cancer metastasis by Aes through inhibition of Notch signaling.

Masahiro Aoki, Makoto Sasaki, Masahiro Sonoshita, 2011, Cancer cell.

Improved synthesis and in vitro/in vivo activities of natural product-inspired, artificial glutamate analogs.

R. Sakai, K. Shimamoto, M. Oikawa, 2010, Bioorganic & medicinal chemistry.

Total synthesis of gymnocin-A.

C. Tsukano, M. Sasaki, 2003, Journal of the American Chemical Society.

Intramolecular radical cyclization-ring-closing metathesis approach to fused polycyclic ethers. Convergent synthesis and conformational analysis of the (E)FGH ring system of ciguatoxin.

K. Tachibana, M. Sasaki, Tetsuji Noguchi, 2002, The Journal of organic chemistry.

Unified Total Synthesis of (-)-Enigmazole A and (-)-15-O-Methylenigmazole A.

H. Fuwa, M. Sasaki, Keita Sakamoto, 2020, Chemistry, an Asian journal.

Tetracyclic Truncated Analogue of the Marine Toxin Gambierol Modifies NMDA, Tau, and Amyloid β Expression in Mice Brains: Implications in AD Pathology.

J. M. Cifuentes, L. Botana, E. Alonso, 2017, ACS Chemical Neuroscience.

Antinociceptive effects of MSVIII-19, a functional antagonist of the GluK1 kainate receptor

R. Sakai, R. Gereau, G. Swanson, 2011, PAIN.

An enantioselective total synthesis of aspergillides A and B

H. Fuwa, M. Sasaki, H. Yamaguchi, 2010 .

Synthesis of the NO ring model of gymnocin-B

C. Tsukano, M. Sasaki, 2005 .

Inhibition of voltage-gated potassium currents by gambierol in mouse taste cells.

T. Yasumoto, G. Rossini, A. Bigiani, 2005, Toxicological sciences : an official journal of the Society of Toxicology.

Gambierol Potently Increases Evoked Quantal Transmitter Release and Reverses Pre- and Post-Synaptic Blockade at Vertebrate Neuromuscular Junctions

D. Servent, L. Botana, M. C. Louzao, 2020, Neuroscience.

Synthesis and Structural Implication of the JKLMN-Ring Fragment of Caribbean Ciguatoxin C-CTX-1.

M. Sasaki, Kotaro Iwasaki, Keisuke Arai, 2021, The Journal of organic chemistry.

Binding and selectivity of the marine toxin neodysiherbaine A and its synthetic analogues to GluK1 and GluK2 kainate receptors.

R. Sakai, K. Doh-ura, M. Ikeda-Saito, 2011, Journal of molecular biology.

ENANTIOSELECTIVE TRANSFORMATION OF PROPARGYL ESTERS TO DIHYDROFURANS

H. Saimoto, H. Sashiwa, Y. Shigemasa, 1991 .

Assignment of the absolute configuration of goniodomin A by NMR spectroscopy and synthesis of model compounds.

M. Oikawa, M. Sasaki, Y. Takeda, 2008, Organic letters.

Complete Stereochemical Assignment of Campechic Acids A and B.

Y. Igarashi, H. Fuwa, M. Sasaki, 2016, The Journal of organic chemistry.

New strategy for convergent synthesis of trans-fused polyether frameworks based on palladium-catalyzed suzuki cross-coupling reaction

K. Tachibana, M. Inoue, H. Fuwa, 1998 .

Synthetic entry to the ABCD ring fragment of gymnocin-A, a cytotoxic marine polyether

K. Tachibana, C. Tsukano, M. Sasaki, 2003 .

New Strategy for Convergent Synthesis of trans-Fused Polyether Frameworks Based on Palladium-Catalyzed Suzuki Cross-Coupling Reaction.

K. Tachibana, M. Inoue, H. Fuwa, 1999 .

Synthesis of (.+-.)-15-deoxybruceolide and conversion of (-)-15-deoxybruceolide into (-)-bruceantin: total synthesis of bruceantin

M. Sasaki, T. Murae, Takeyoshi Takahashi, 1990 .

Synthesis of Bulky N‐Acyl Heterocycles by DMAPO/Boc2O‐Mediated One‐Pot Direct N‐Acylation of Less Nucleophilic N‐Heterocycles with α‐Fully Substituted Carboxylic Acids

M. Sasaki, Atsushi Umehara, Soma Shimizu, 2023, Advanced Synthesis & Catalysis.

Stereocontrolled Synthesis of the DEFG-ring Skeleton of Gambieric Acids

H. Fuwa, M. Sasaki, Sayaka Noji, 2009 .

SYNTHESIS AND BIOLOGICAL ACTIVITY OF DYSIHERBAINE MODEL COMPOUND

R. Sakai, K. Tachibana, M. Sasaki, 1999 .

Full Domain Closure of the Ligand-binding Core of the Ionotropic Glutamate Receptor iGluR5 Induced by the High Affinity Agonist Dysiherbaine and the Functional Antagonist 8,9-Dideoxyneodysiherbaine*

R. Sakai, P. Naur, J. Kastrup, 2009, Journal of Biological Chemistry.

Binding Modes and the Selectivity of the Compounds Bound to the Kainate-Type Glutamate Receptors at Atomic Level Resolution

R. Sakai, M. Ikeda-Saito, M. Sasaki, 2012 .

Design, total synthesis, and biological evaluation of neodysiherbaine A derivative as potential probes.

R. Sakai, K. Shimamoto, M. Oikawa, 2006, Bioorganic & medicinal chemistry letters.

Brewing characteristics of sake yeast resistant to an inhibitor of mitochondrial pyruvate transport for brewing low alcohol sake on a pilot scale.

T. Oba, H. Kitagaki, M. Sasaki, 2011 .

Potassium currents inhibition by gambierol analogs prevents human T lymphocyte activation

C. Vale, J. Rubiolo, H. Fuwa, 2015, Archives of Toxicology.

Total synthesis of (-)-exiguolide.

H. Fuwa, M. Sasaki, 2010, Organic letters.

Convergent strategies for the total synthesis of polycyclic ether marine metabolites.

H. Fuwa, M. Sasaki, 2008, Natural product reports.

Total synthesis of the proposed structure of brevenal.

H. Fuwa, M. Sasaki, Makoto Ebine, 2006, Journal of the American Chemical Society.

Complete Stereochemical Assignment of Campechic Acids A and B.

Y. Igarashi, H. Fuwa, M. Sasaki, 2016, The Journal of organic chemistry.

A concise total synthesis of (+)-neopeltolide.

Asami Saito, H. Fuwa, M. Sasaki, 2010, Angewandte Chemie.

Total synthesis and structure revision of didemnaketal B.

H. Fuwa, M. Sasaki, T. Muto, 2014, Chemistry.

Synthesis of dysiherbaine analogue

R. Sakai, M. Oikawa, M. Sasaki, 2005 .

Design and synthesis of skeletal analogues of gambierol: attenuation of amyloid-β and tau pathology with voltage-gated potassium channel and N-methyl-D-aspartate receptor implications.

F. LaFerla, C. Vale, M. Vieytes, 2012, Journal of the American Chemical Society.