R. Adlington

发表

Total synthesis of panepophenanthrin.

J. Baldwin, J. Moses, L. Commeiras, 2003, Organic letters.

The enzymatic synthesis of isotopically labelled penicillin Ns with isopenicillin N synthase

J. Baldwin, I. Pereira, R. Adlington, 1998 .

Syntheses of (6S)-Cephalosporins from 6-Aminopenicillanic Acid

C. Schofield, J. Baldwin, R. Adlington, 2000 .

Isolation of an intermediate in clavulanic acid biosynthesis

M. D. Lloyd, C. Schofield, J. Bryans, 1990 .

Isolation of dihydroclavaminic acid, an intermediate in the biosynthesis of clavulanic acid

M. D. Lloyd, C. Schofield, J. Bryans, 1991 .

Enzymatic synthesis of bicyclic γ-lactams using clavaminic acid synthase

M. D. Lloyd, C. Schofield, J. Bryans, 1992 .

Investigation of the stereospecificity of clavaminic acid synthase in the desaturation of dihydroclavaminic acid to clavaminic acid

J. Baldwin, R. Adlington, N. Crouch, 1994 .

Trifluoromethyl alcohol and ketone inhibitors of metallo-β-lactamases

J. Frère, M. Galleni, C. Schofield, 1996 .

Purification of isopenicillin N synthetase.

J. Baldwin, H. Ting, E. Abraham, 1984, The Biochemical journal.

Stereospecificity of carbon–sulphur bond formation in penicillin biosynthesis

N. Turner, J. Baldwin, H. Ting, 1986 .

Incorporation of 18O-labelled water into oxygenated products produced by the enzyme deacetoxy/deacetylcephalosporin C synthase

J. Baldwin, I. Pereira, R. Adlington, 1993 .

Regio- and stereospecific [3+2] cycloaddition of an unusual nitrone derived from a N-hydroxy-2-pyridone with medium ring enones

A. Cowley, J. Baldwin, G. Pritchard, 2005 .

Synthesis of chiral isoxazolidin-5-ones and their applications to the synthesis of β-amino-alanines and β-(N-hydroxyamino)-alanines

J. Baldwin, R. Adlington, Lisa C. Mellor, 1994 .

Synthesis of new bulky bis(pyrazolyl)methane carboxylate (heteroscorpionate) ligands and their complexes with iron, manganese and nickel.

J. Dilworth, A. Cowley, J. Baldwin, 2012, Dalton transactions.

Stereocontrolled enantiospecific synthesis of anticapsin

J. Baldwin, R. Adlington, M. Mitchell, 1995 .

Stereocontrolled enantiospecific synthesis of anticapsin: revision of the configuration

J. Baldwin, R. Adlington, M. Mitchell, 1993 .

New mononuclear Pd(II) complexes of sterically hindered bispyrazolylmethanes

J. Baldwin, Michael W. Jones, R. Adlington, 2010 .

Total synthesis of a novel 2-thiabicyclo[3.2.0]heptan-6-one analogue of penicillin N

P. Rutledge, A. Cowley, J. Baldwin, 2003 .

New Penicillins from Isopenicillin N Synthase.

M. Bradley, J. Baldwin, R. Adlington, 1991 .

Penicillin biosynthesis: enzymatic synthesis of new cephams

N. Turner, J. Baldwin, H. Ting, 1985 .

Penicillin biosynthesis: active site mapping with aminoadipoylcysteinylvaline variants

Robert L. White, N. Turner, S. Flitsch, 1984 .

An expedient synthesis of trisubstituted allenes

J. Baldwin, R. Adlington, N. Crouch, 1995 .

Design, synthesis, and proposed active site binding analysis of monocyclic 2-azetidinone inhibitors of prostate specific antigen.

G. Becker, B. Neubauer, R. Hermann, 2001, Journal of medicinal chemistry.

Studies on the mechanism of deacetoxy–deacetylcephalosporin C synthase using cyclopropyl substituted cephalosporin probes

C. Schofield, S. Leppard, M. Wood, 1991 .

Prostate-specific antigen (PSA)-mediated proliferation, androgenic regulation and inhibitory effects of LY312340 in HOS-TE85 (TE85) human osteosarcoma cells.

E. Dixon, G. Becker, B. Neubauer, 2002, Anticancer research.

Sir Jack Baldwin, FRS: biomimetic studies at Oxford.

J. Moses, R. Adlington, 2005, Chemical communications.

Towards a Biomimetic Synthesis of the Marine Alkaloids Papuamine and Haliclonadiamine: Model Studies

G. Challis, J. Baldwin, R. Adlington, 2000 .

Conversion of 17O/18O-labelled δ-(L-α-aminoadipyl)–L-cycteinyl–D-valine into 17O/18O-labelled isopenicillin N in a cell-free extract of C. acremonium

Robert L. White, R. Aplin, L. Field, 1982 .

Ring-nitrogen of β-isoxazolinone-alanine is incorporated into the neurotoxin β-N-oxalyl-l-α,β-diaminopropionic acid, in callus tissue of Lathyrus sativus

J. Baldwin, R. Adlington, F. Lambein, 1994 .

The biomimetic synthesis of SNF4435C and SNF4435D, and the total synthesis of the polyene metabolites aureothin, N-acetyl-aureothamine and spectinabilin

M. Jacobsen, J. Baldwin, J. Moses, 2006 .

Expedient synthesis of a highly substituted tropolone via a 3-oxidopyrylium [5+2] cycloaddition reaction

A. Mayweg, J. Baldwin, R. Adlington, 2003 .

Synthesis of substituted pyrano[3,2-c]pyridines via Diels–Alder reaction of 3-methylenepyridin-4-one

J. Baldwin, K. Tchabanenko, R. Adlington, 2006 .

Synthesis of novel C-nucleosides with potential applications in combinatorial and parallel synthesis

J. Baldwin, R. Adlington, G. J. Pritchard, 2000 .

Recent applications of the Shapiro reaction

A. Barrett, R. Adlington, 1983 .

Radical reactions in synthesis: carbon–carbon bond formation from 2-substituted allyl trialkyl stannanes

J. Baldwin, J. Sweeney, R. Adlington, 1986 .

Practical routes to diacetylenic ketones and their application for the preparation of alkynyl substituted pyridines, pyrimidines and pyrazoles

Mauro F. A. Adamo, J. Baldwin, R. Adlington, 2003 .

New access to the 1H-pyrazolo[4,3-c]pyridine core from bis-acetylenic-N-benzoylhydrazones

S. C. Woodcock, A. Cowley, J. Baldwin, 2004 .

A short biomimetic synthesis of the meroterpenoids guajadial and psidial A.

J. Baldwin, R. Adlington, Jessica A. Kershaw, 2010, Organic letters.

A novel entry to carbenoid species viaβ-ketosulfoxonium ylides

J. Baldwin, R. Adlington, C. Godfrey, 1993 .

Studies towards the biomimetic synthesis of pyridomacrolidin

A. Cowley, J. Baldwin, R. Adlington, 2006 .

Total synthesis of pyridovericin

J. Baldwin, A. Conte, R. Adlington, 2004 .

An unusual oxidative cyclization: studies towards the biomimetic synthesis of pyridomacrolidin.

A. Cowley, J. Baldwin, R. Adlington, 2003, Organic letters.

Total synthesis of pyridovericin: studies toward the biomimetic synthesis of pyridomacrolidin.

J. Baldwin, A. Conte, R. Adlington, 2002, Organic letters.

Design and synthesis of novel monocyclic β-lactam inhibitors of prostate specific antigen

G. Becker, B. Neubauer, R. Hermann, 1997 .

The reaction cycle of isopenicillin N synthase observed by X-ray diffraction

P. Roach, P. Rutledge, N. Burzlaff, 1999, Nature.

Synthesis of δ-L-α-aminoadipoyl-L-cysteinyl-D-allylglycine, and eight deuterated analogues, substrates for the investigation of the mechanism of action of isopenicillin N synthase

M. Bradley, A. Pitt, H. Sheridan, 1991 .

Enzymic conversion of deuterated analogues of δ--α-aminoadipoyl--cysteinyl--allylglycine, an unnatural substrate for isopenicilin n synthase: A unified theory of second ring closure.

M. Bradley, A. Pitt, N. Turner, 1991 .

Use of the cyclopropylcarbinyl test to detect a radical-like intermediate in penicillin biosynthesis

J. Baldwin, H. Ting, R. Adlington, 1987 .

Stepwise ring closure in penicillin biosynthesis. Intitial β-lactam formation

S. Moroney, L. Field, J. Baldwin, 1984 .

The efficient, enantioselective synthesis of quinoxaline, pyrazine and 1,2,4-triazine substituted α-amino acids from vicinal tricarbonyls

J. Baldwin, R. Adlington, D. Catterick, 2001 .

A short total synthesis of aureothin and N-acetylaureothamine.

M. Jacobsen, J. Baldwin, J. Moses, 2005, Organic letters.

Studies on the biomimetic synthesis of SNF4435 C and D.

A. Cowley, J. Baldwin, J. Moses, 2002, Organic letters.

A novel oxidative rearrangement of 6-methoxypyran-2-ones.

M. Walter, A. Cowley, J. Baldwin, 2005, Organic letters.

The synthesis of pyrimidin-4-yl substituted α-amino acids. A versatile approach from alkynyl ketones

J. Baldwin, R. Adlington, D. Catterick, 1999 .

Chemo-enzymatic synthesis of bicyclic γ-lactams using clavaminic acid synthase

M. D. Lloyd, C. Schofield, J. Bryans, 1997 .

Synthesis of rac-Lindenene via a thermally induced cyclopropanation reaction.

Michael W. Jones, R. Adlington, Victor C. S. Lee, 2013, Organic & biomolecular chemistry.

Dimerization of butenolide structures. A biomimetic approach to the dimeric sesquiterpene lactones (+/-)-biatractylolide and (+/-)-biepiasterolide.

S. Bagal, J. Baldwin, R. Adlington, 2004, The Journal of organic chemistry.

Studies Towards the Biomimetic Synthesis of Bisesquiterpene Lactones

S. Bagal, A. Cowley, J. Baldwin, 2003 .

Synthesis of linked heterocycles via use of bis-acetylenic compounds

C. Smith, J. Baldwin, K. Tchabanenko, 2006 .

The synthesis of novel heterocyclic substituted α-amino acids; further exploitation of α-amino acid alkynyl ketones

J. Baldwin, R. Adlington, D. Catterick, 2000 .

A versatile approach to pyrimidin-4-yl substituted α-aminoacids from alkynyl ketones; the total synthesis of l-lathyrine

J. Baldwin, R. Adlington, D. Catterick, 1997 .

A study of the intramolecular stille cross coupling reaction of vinylstannyl chloroformates: application to the synthesis of α-methylene lactones

J. Baldwin, R. Adlington, A. Russell, 1994 .

Synthesis of a novel thiabicyclo[3.2.0]heptan-6-one analogue of penicillin

M. Probert, D. Watkin, J. Baldwin, 2001 .

Azo anions in synthesis. t-Butylhydrazones as acyl-anion equivalents

J. Baldwin, R. Adlington, J. Bottaro, 1983 .

Total Synthesis of Pyridovericin.

J. Baldwin, A. Conte, R. Adlington, 2005 .

Synthesis of n-benzyloxycarbonyl-l-α-aminoadipic acid, α-benzyl ester

J. Baldwin, R. Adlington, S. J. Killin, 1988 .

An Investigation of the N-Arylsulfonylation of 2-Azetidinones

N. Westwood, C. Schofield, J. Baldwin, 1997 .

Carbocyclic ring expansion reactiuon VIA radical chain processes

J. Robertson, J. Baldwin, R. Adlington, 1989 .

The ring expansion of penama to cephams: a possible biomimetic process

C. Schofield, J. Baldwin, R. Adlington, 1988 .

The synthesis and antimicrobial activity of (1s,2s)-1-hydroxy-2-[(s)-valylamino]cyclobutane-1-acetic acid (1) and (1s, 2s)-1-hydroxy-2-aminocyclobutane-1-acetic acid (2)

J. Baldwin, H. Ting, M. F. Parisi, 1986 .

Stereospecific synthesis of (1S,2S)-1-hydroxy-2-[(S)-valylamino]-cyclobutane-1-acetic acid, a novel microbial antimetabolite

J. Baldwin, Richard H. Jones, M. F. Parisi, 1983 .

New Domino Silyl Enol Ether Reactions in the Synthesis of a Tetrodecamycin Fragment

A. Cowley, J. Baldwin, K. Tchabanenko, 2006 .

The synthesis of novel heterocyclic substituted α-amino acids; further exploitation of α-amino acid alkynyl ketones as reactive substrates

J. Baldwin, R. Adlington, D. Catterick, 2000 .

Carbon based nucleophilic ring opening of activated monocyclic β-lactams; Synthesis and stereochemical assignment of the ACE inhibitor WF-10129

J. Baldwin, R. Adlington, A. Russell, 1995 .

Penicillin biosynthesis the immediate origin of the sulphur atom

D. Arigoni, J. Baldwin, H. Ting, 1985 .

Design and Synthesis of Novel Monocyclic β-Lactam Inhibitors of Prostate Specific Antigen.

G. Becker, B. Neubauer, R. Hermann, 1997 .

Stereospecific synthesis of dealanylalahopcin

C. Schofield, J. Baldwin, R. Adlington, 1990 .

Synthesis of L-quisqualic acid: a general method for enantio-efficient synthesis of β-aminoalanine derivatives

J. Baldwin, R. Adlington, D. Birch, 1985 .

Biomimetic synthesis of polycyclic polyprenylated acylphloroglucinol natural products isolated from Hypericum papuanum.

J. Baldwin, R. Adlington, M. Hesse, 2010, Organic letters.

Enzymic Conversion of Deuterated Analogues of δ-L-α- Aminoadipoyl-L-cysteinyl-D-allylglycine, an Unnatural Substrate for Isopenicillin N Synthase: A Unified Theory of Second Ring Closure

M. Bradley, A. Pitt, N. Turner, 1992 .

Terminally Truncated Isopenicillin N Synthase Generates a Dithioester Product: Evidence for a Thioaldehyde Intermediate during Catalysis and a New Mode of Reaction for Non‐Heme Iron Oxidases

C. Schofield, P. Rutledge, T. Claridge, 2017, Chemistry.

Unexpected Oxidation of a Depsipeptide Substrate Analogue in Crystalline Isopenicillin N Synthase

P. Rutledge, I. Clifton, J. Baldwin, 2006, Chembiochem : a European journal of chemical biology.

Synthesis of δ‐L‐α‐Aminoadipoyl‐L‐cysteinyl‐D‐allylglycine (I), and Eight Deuterated Analogues, Substrates for the Investigation of the Mechanism of Action of Isopenicillin N Synthase.

M. Bradley, A. Pitt, H. Sheridan, 1992 .

The synthesis and reactions of a monocyclic β-lactam tripeptide, 1-[(1R)-carboxy-2-methylpropyl]- (3R -[(5S-5-amino- 5-carboxypentanamido]-(4R)-mercaptoazetidin-2-one, a putative intermediate in penicillin biosynthesis

Robert L. White, L. Field, J. Baldwin, 1984 .

Novel syntheses of 3-methylene-azetidin-2-one derivatives and related systems

A. Barrett, M. J. Betts, R. Adlington, 1981 .

Biomimetic synthesis of pyrone-derived natural products: exploring chemical pathways from a unique polyketide precursor.

M. Walter, J. Baldwin, J. Moses, 2008, The Journal of organic chemistry.

Recent applications of the Shapiro reaction

A. Barrett, R. Adlington, 1983 .

A versatile synthetic route to quinoxaline, pyrazine and 1,2,4-triazine substituted α-amino acids from vicinal tricarbonyls

J. Baldwin, R. Adlington, D. Catterick, 2000 .

A parallel synthesis approach towards a family of C-nucleosides

Mauro F. A. Adamo, J. Baldwin, R. Adlington, 2004 .

The preparation and reactions of 1-lithio-alkylamino-1-lithio-oxy-allene derivatives

A. Barrett, R. Adlington, 1981 .

Direct Ring Expansion of Penicillins to 3-Exomethylene Cephalosporins

J. Baldwin, R. Adlington, T. Kang, 1991 .

Biomimetic studies on polyenes.

J. Baldwin, J. Moses, R. Adlington, 2003, Organic & biomolecular chemistry.

Biomimetic synthesis of the crispatene core.

T. Claridge, J. Baldwin, J. Moses, 2003, Organic letters.

Azo anions in synthesis: α-amino carbanion equivalents from t-butyldiphenyl-methylhydrazones

J. Baldwin, R. Adlington, I. Newington, 1986 .

Azo anions in systhesis. pt 1. t-butylhydrazones as acyl-anion equivalents

J. Baldwin, J. Bottaro, M. Perry, 1986 .

A Short Asymmetric Synthesis of (R,R)-(-)-Pyrenophorin

J. Baldwin, R. Adlington, S. H. Ramcharitar, 1992 .

Azo anions in synthesis : Use of trityl- and diphenyl-4-pyridylmethylhydrazones for reductive C-C bond formation

J. Baldwin, M. Perry, J. Kolhe, 1986 .

Carbocyclic ring expansion reactions via free radical pathways - part III

J. Baldwin, R. Adlington, Rajinder Singh, 1992 .

Allene transfer reactions. A new synthesis of terminal allenes

J. Baldwin, A. Basak, R. Adlington, 1985 .

Regioselectivity of dimerisation of butenolides via captodative stabilised radicaloid intermediates

S. Bagal, J. Baldwin, R. Adlington, 2005 .

Thermal and palladium catalyzed pericyclic rearrangements of a pentaene ester

T. Claridge, J. Baldwin, B. Odell, 2004 .

Intramolecular SH2′ macrocyclisations

J. Robertson, J. Baldwin, R. Adlington, 1991 .

Radical reactions in synthesis: intramolecular SH2′ macrocyclisations

J. Robertson, J. Baldwin, R. Adlington, 1990 .

Evidence for an insertion-homolysis mechanism for carbon-sulphur bond formation in penicillin biosynthesis .1. Synthesis of tripeptide probes

A. Pitt, J. Baldwin, R. Adlington, 1996 .

Enantiospecific, biosynthetically inspired formal total synthesis of (+)-liphagal.

J. Baldwin, R. Adlington, J. George, 2010, Organic letters.

Applications of the thermal ene reaction of aldehyde t-butyl- and phenyl-hydrazones

J. Baldwin, M. Perry, J. Kolhe, 1986 .

Azo anions in synthesis. Use of trityl- and diphenyl-4-pyridylmethyl-hydrazones for reductive C–C bond formation from aldehydes and ketones

J. Baldwin, J. Bottaro, J. Kolhe, 1984 .

Michael additions of hydrazones for carbon–carbon bond formation

J. Baldwin, J. Bottaro, M. Perry, 1984 .

Improved Synthesis of α-Methylene-γ-lactones via Organotin Reagents.

J. Baldwin, J. Sweeney, R. Adlington, 1987 .

The role of α-ketoglutarate in cephalosporin biosynthesis

C. Schofield, M. Wood, J. Baldwin, 1989 .

Applications of radical addition reactions to the synthesis of a C-glucoside and a functionalised amino-acid

J. Baldwin, A. Basak, R. Adlington, 1983 .

Biomimetic synthetic studies on meroterpenoids from the marine sponge Aka coralliphaga: Divergent total syntheses of siphonodictyal B, liphagal and corallidictyals A-D.

J. Baldwin, R. Adlington, Adrian W Markwell-Heys, 2019, Bioorganic & medicinal chemistry.

Free radical macrocyclisation via propiolate esters

J. Baldwin, R. Adlington, S. H. Ramcharitar, 1992 .

Investigations towards the synthesis of (-)-coprinolone, via a thermal 8π-6π electrocyclization cascade of 1,5,7-trien-4-ones

H. Wegner, M. Jacobsen, J. Baldwin, 2006 .

Synthesis of a biologically active analogue of antibiotic A-32390A

J. Baldwin, R. Adlington, A. Russell, 1994 .

The Efficient, Enantioselective Synthesis of Quinoxaline, Pyrazine and 1,2-4-Triazine Substituted α-Amino Acids from Vicinal Tricarbonyls.

J. Baldwin, R. Adlington, D. Catterick, 2001 .

Syntheses of (6S,7S)- and (6S,7R)-deacetoxycephalosporanic acids from 6-aminopenicillanic acid

C. Schofield, J. Baldwin, R. Adlington, 1996 .

Cephalosporin C biosynthesis : On the mechanism of hydroxylation of deacetoxycephalosporin C to deacetylcephalosporin C.

R. Aplin, J. Baldwin, R. Adlington, 1992 .

The enzymatic conversion of exomethylene cephalosporin c into deacetyl cephalosporin c and the role of molecular oxygen in cephalosporin c biosynthesis

C. Schofield, J. Baldwin, R. Adlington, 1988 .

Total synthesis of cyercene A and the biomimetic synthesis of (±)-9,10-deoxytridachione and (±)-ocellapyrone A

M. Walter, J. Baldwin, J. Moses, 2007 .

A Short Total Synthesis of Aureothin (Ia) and N‐Acetylaureothamine (Ib).

M. Jacobsen, J. Baldwin, J. Moses, 2005 .

The total synthesis of spectinabilin and its biomimetic conversion to SNF4435C and SNF4435D.

M. Jacobsen, J. Baldwin, J. Moses, 2005, Organic letters.

An efficient synthesis of cyercene A

J. Baldwin, J. Moses, R. Adlington, 2004 .

Studies on the biomimetic synthesis of SNF4435 C and D.

A. Cowley, J. Baldwin, J. Moses, 2002, Organic letters.

A new and efficient method for o-quinone methide intermediate generation: application to the biomimetic synthesis of the benzopyran derived natural products (+/-)-lucidene and (+/-)-alboatrin.

J. Baldwin, J. Moses, R. Adlington, 2005, Organic & biomolecular chemistry.

A new and efficient method for o-quinone methide intermediate generation: application to the biomimetic synthesis of (+/-)-Alboatrin.

A. Cowley, J. Baldwin, J. Moses, 2004, Organic letters.

Biomimetic cycloaddition approach to tropolone natural products via a tropolone ortho-quinone methide.

A. Mayweg, J. Baldwin, R. Adlington, 2002, Organic letters.

Base-assisted intramolecular 6-acetoxypyranone-acetylene [5+2] cycloaddition. Synthesis and reactivity of novel oxa-tricyclo[5.3.1.01,5]undecenones

J. Baldwin, Sylvain Celanire, F. Marlin, 2005 .

A New and Efficient Method for o‐Quinone Methide Intermediate Generation: Application to the Biomimetic Synthesis of the Benzopyran Derived Natural Products (.+‐.)‐Lucidene and (.+‐.)‐Alboatrin.

J. Baldwin, J. Moses, R. Adlington, 2006 .

A biomimetic synthesis of lucidene.

D. Watkin, J. Baldwin, A. Williams, 1999, Organic letters.

A New and Efficient Method for o‐Quinone Methide Intermediate Generation: Application to the Biomimetic Synthesis of (.+‐.)‐Alboatrin.

A. Cowley, J. Baldwin, J. Moses, 2005 .

Intramolecular palladium-catalysed cross coupling; a direct route to γ-Oxo-α,β-unsaturated macrocycles.

J. Baldwin, R. Adlington, S. H. Ramcharitar, 1992 .

ASYMMETRIC TOTAL SYNTHESIS OF THE INDIVIDUAL DIASTEREOISOMERS OF HYPOGLYCIN A

J. Baldwin, R. Adlington, A. Russell, 1995 .

Biomimetic rearrangements of simplified labdane diterpenoids

J. Baldwin, R. Adlington, J. George, 2010 .

Biomimetic synthesis of biatractylolide and biepiasterolide.

S. Bagal, A. Cowley, J. Baldwin, 2003, Organic letters.

On the stereochemistry of ethylene biosynthesis

J. Baldwin, R. Adlington, B. Rawlings, 1983 .

The resolution of racemic 2-alkyl-1-aminocyclopropane-1-carboxylic acids

J. Baldwin, Richard H. Jones, R. Adlington, 1985 .

A convenient synthesis of regio-specifically 2-alkylated-3-deuteriated-1-aminocyclopropane-1-carboxylic acids

J. Baldwin, R. Adlington, B. Rawlings, 1985 .

On the biosynthesis of ethylene. Determination of the stereochemical course using modified substrates

G. Lajoie, J. Baldwin, R. Adlington, 1985 .

The stereochemistry of oxidation of 1-amino-cyclopropanecarboxylic acid

D. Jackson, J. Baldwin, R. Adlington, 1985 .

Unique binding of a non-natural L,L,L-substrate by isopenicillin N synthase.

P. Rutledge, I. Clifton, J. Baldwin, 2005, Biochemical and biophysical research communications.

Unusual stereospecificity in the hydrogenation of an isopropenyl function with Wilkinson's catalyst; a route to chiral methyl valine

J. Baldwin, D. Crout, R. Adlington, 1981 .

On the biosynthesis of ethylene

R. Aplin, J. Baldwin, R. Adlington, 1982 .

Purification and initial characterization of an enzyme with deacetoxycephalosporin C synthetase and hydroxylase activities.

C. Schofield, M. Crabbe, J. Baldwin, 1987, The Biochemical journal.

An efficient substitute for the α-amimoadipoyl moiety of δ-(-α-aminloadipoytl)--cisteintl--valine in the emzymatic synthesis of penicillins

C. Schofield, M. Crabbe, J. Baldwin, 1987 .

On the biosynthesis of ethylene: further evidence for stepwise enzymatic cyclopropane ring cleavage

G. Lajoie, J. Baldwin, R. Adlington, 1988 .

Synthetic Approaches to 2-Methoxycysteine containing Peptides. The conversion of [(5S)-5-amino-5-carboxy-2-oxapentanoyl]-2-methoxy-(2S)-cysteinyl-(2R)-valine into 10-Oxa-6α-methoxyisopenicillin N by the Enzyme Isopenicillin N Synthase

N. Moss, J. Baldwin, R. Adlington, 1989 .

Interactions of isopenicillin N synthase with cyclopropyl-containing substrate analogues reveal new mechanistic insight.

J. Elkins, P. Roach, P. Rutledge, 2007, Biochemistry.

Structure and synthesis of new cyclopentenyl isonitriles from Trichoderma hamatum (Bon.) Bain. aggr. HLX 1379

J. Baldwin, C. Ziegler, J. W. Keeping, 1985 .

Synthesis of L-β-(isoxazolin-5-one-2-yl)-alanine: a novel method for the synthesis of N-substituted 3,4-unsubstituted isoxazolin-5-ones

J. Baldwin, R. Adlington, D. Birch, 1985 .

A Synthetic Approach to theCommunesins

R. Adlington, J. George, 2008 .

Evidence for an insertion-homolysis mechanism for carbon-sulphur bond formation in penicillin biosynthesis; 2. Incubation and interpretation

A. Pitt, J. Baldwin, R. Adlington, 1996 .

Enantiospecific synthesis of dealanylalahopcin

C. Schofield, J. Baldwin, R. Adlington, 1990 .

Biomimetic synthesis of (′)-aculeatin D

J. Baldwin, P. Bulger, R. Adlington, 2005 .

Studies towards the Synthesis of Lindenene: Unexpected Stereochemical Outcome of an Intramolecular Cyclopropanation Reaction and Synthesis of (±)-epi-Lindenene and (±)-iso-Lindenene

A. Mayweg, J. Baldwin, R. Adlington, 2007 .

Synthesis of epi-Chloranthalactones A, B, D and E

Michael W. Jones, R. Adlington, Victor C. S. Lee, 2018, Synlett.

Cephalosporin biosynthesis: A branched pathway sensitive to an isotope effect

C. Schofield, N. Turner, R. Aplin, 1991 .

Reinvestigation of the dimerisation process forming isoglaucanic acid

D. Watkin, J. Baldwin, R. Adlington, 1999 .

Intramolecular palladium-catalysed cross coupling; a route to γ-oxo-α,β-unsaturated macrocycles

J. Baldwin, R. Adlington, S. H. Ramcharitar, 1991 .

An unusual oxidative cyclization: studies towards the biomimetic synthesis of pyridomacrolidin.

A. Cowley, J. Baldwin, R. Adlington, 2003, Organic letters.

Total synthesis of the epoxyquinol dimer (+)-panepophenanthrin: application of a diastereospecific biomimetic Diels–Alder dimerisation

G. Grant, A. Cowley, J. Baldwin, 2006 .

The total synthesis of (±)-trichoviridin

J. Baldwin, I. O'neil, R. Adlington, 1996 .

Application of bis-acetylenic ketones in synthesis: one-pot preparation of the 1,2,4-triazepine and oxatriazaindenone cores.

Mauro F. A. Adamo, J. Baldwin, R. Adlington, 2005, The Journal of organic chemistry.

Nucleophilic ring opening of aziridine-2-carboxylates with Wittig reagents; an enantioefficient synthesis of unsaturated amino acids

J. Baldwin, R. Adlington, N. G. Robinson, 1987 .

A new method for C–C coupling of terminal alkenes via a sulphonylation–alkylation–desulphinylation sequence: synthesis of E- and Z-α-bisabolenes

J. Baldwin, R. Adlington, Y. Ichikawa, 1988 .

Desulfhurisation of Penicillins with Triphenylstannane

J. Baldwin, V. Patel, R. Adlington, 1989 .

Reactions of a glycidyl radical equivalent with 2-functionalised allyl stannanes

C. Schofield, J. Baldwin, J. Sweeney, 1988 .

Reaction of (Trifluoromethyl)trimethylsilane with Oxazolidin-5-ones: Synthesis of Peptidic and Nonpeptidic Trifluoromethyl Ketones

C. Schofield, M. Walter, J. Baldwin, 1998 .

Biomimetic synthesis of (+/-)-9,10-deoxytridachione.

J. Baldwin, J. Moses, R. Adlington, 2005, Chemical communications.

The Interaction of Isopenicillin N Synthase with Homologated Substrate Analogues δ‐(L‐α‐Aminoadipoyl)‐L‐homocysteinyl‐D‐Xaa Characterised by Protein Crystallography

P. Rutledge, I. Clifton, J. Baldwin, 2013, Chembiochem : a European journal of chemical biology.

The crystal structure of isopenicillin N synthase with a dipeptide substrate analogue.

P. Rutledge, I. Clifton, J. Baldwin, 2013, Archives of biochemistry and biophysics.

The crystal structure of isopenicillin N synthase with δ-((L)-α-aminoadipoyl)-(L)-cysteinyl-(D)-methionine reveals thioether coordination to iron.

P. Rutledge, I. Clifton, J. Baldwin, 2011, Archives of biochemistry and biophysics.

Isopenicillin N Synthase Binds δ‐(L‐α‐Aminoadipoyl)‐L‐Cysteinyl‐D‐Thia‐allo‐Isoleucine through both Sulfur Atoms

P. Rutledge, I. Clifton, J. Baldwin, 2011, Chembiochem : a European journal of chemical biology.

Crystallographic studies on the binding of selectively deuterated LLD- and LLL-substrate epimers by isopenicillin N synthase.

Jeanette E. Stok, P. Rutledge, I. Clifton, 2010, Biochemical and biophysical research communications.

The crystal structure of an LLL-configured depsipeptide substrate analogue bound to isopenicillin N synthase.

Jeanette E. Stok, P. Rutledge, I. Clifton, 2010, Organic & biomolecular chemistry.

Structural Studies on the Reaction of Isopenicillin N Synthase with a Sterically Demanding Depsipeptide Substrate Analogue

P. Rutledge, I. Clifton, J. Baldwin, 2009, Chembiochem : a European journal of chemical biology.

A Cyclobutanone Analogue Mimics Penicillin in Binding to Isopenicillin N Synthase

P. Rutledge, I. Clifton, J. Baldwin, 2007, Chembiochem : a European journal of chemical biology.

Crystallographic studies on the reaction of isopenicillin N synthase with an unsaturated substrate analogue.

J. Elkins, P. Roach, P. Rutledge, 2003, Organic & biomolecular chemistry.

Alternative oxidation by isopenicillin N synthase observed by X-ray diffraction.

J. Elkins, P. Roach, J. M. Ogle, 2001, Chemistry & biology.

Stereochemical course of the conversion of α-ketoisocaproate to β-hydroxyisovalerate by soluble, recombinant mammalian 4-hydroxyphenylpyruvate dioxygenase☆

J. Baldwin, R. Adlington, N. Crouch, 1997 .

A mechanistic rationalisation for the substrate specificity of recombinant mammalian 4-hydroxyphenylpyruvate dioxygenase (4-HPPD)

J. Baldwin, R. Adlington, N. Crouch, 1997 .

Water exchange of intermediates in a non-haem iron, α-ketoglutarate dioxygenase, deacetoxy-/deacetylcephalosporin C synthase

C. Robinson, R. Aplin, J. Baldwin, 1993 .

Synthesis of metallo-β-lactamase inhibitors

C. Schofield, M. Walter, J. Baldwin, 1997 .

Hydroxamate Inhibitors ofAeromonas hydrophilaAE036 Metallo-B-lactamase

Christopher J. Schofield, Magnus W. Walter, Gianfranco Amicosante, 1999 .

Synthesis of Metallo-β-lactamase Inhibitors.

C. Schofield, M. Walter, J. Baldwin, 1997 .

Reaction of ruppert's reagent (TMS-CF3) with Oxazolidinones: Synthesis of protected α-amino trifluoromethylketones

C. Schofield, M. Walter, J. Baldwin, 1995 .

Enantiospecific synthesis of (3r, 4r)-3-amino-1-hydroxy-4-methyl pyrrolidin-2-one (l-687,414), an nmda receptor antagonist

J. Baldwin, R. Adlington, A. Elend, 1995 .

Thermally induced cascade pericyclic reaction pathways from tetraene esters

A. Cowley, J. Baldwin, J. Moses, 2003 .

Stereochemistry of hydroxylation during the conversion of α-ketoisocaproate to β-hydroxyisovalerate by 4-hydroxyphenylpyruvate dioxygenase

J. Baldwin, R. Adlington, D. R. Paul, 1996 .

Isolation of Dihydroclavaminic Acid (I), an Intermediate in the Biosynthesis of Clavulanic Acid

M. D. Lloyd, C. Schofield, J. Bryans, 1991 .

Substrate specificity of cloned deacetoxycephalosporin C/deacetylcephalosporin C synthetase.

C. Schofield, J. Sutherland, J. Baldwin, 1988, The Journal of antibiotics.

γ-Lactam analogues of carbapenicillanic acids

C. Schofield, J. Baldwin, R. Adlington, 1985 .

A study of the biosynthesis of the tripeptide delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine in a beta-lactam-negative mutant of Cephalosporium acremonium.

J. Baldwin, R. Adlington, J. Murphy, 1983, The Biochemical journal.

Studies on the exchange of valine-oxygen during the biosynthesis of δ-(L-α-Aminoadipoyl)-L-cysteinyl-D-valine.

R. Field, C. Schofield, J. Baldwin, 1992 .

Mechanistic evidence supporting the biosynthesis of photodeoxytridachione

A. Cowley, J. Baldwin, J. Moses, 2003 .

Substrate specificity of recombinant Streptomyces clavuligerus deacetoxycephalosporin C synthase.

I. Andersson, J. Sutherland, J. Baldwin, 1994 .

Evidence for epoxidase activity in deacetoxy/deacetylcephalosporin C synthase

J. Baldwin, I. Pereira, R. Adlington, 1993 .

Substrate specificity of soluble recombinant deacetoxycephalosporin C/deacetylcephalosporin C synthase

R. Heath, J. Sutherland, J. Baldwin, 1992 .

Cephalosporin Biosynthesis: A Branched Pathway Sensitive to an Isotope Effect.

C. Schofield, N. Turner, R. Aplin, 1992 .

Further evidence for the involvement of a monocyclic β-lactam in the enzymatic conversion of δ-L-α-aminoadipoyl-L-cysteinyl-D-valine into isopenicillin N.

M. Bradley, N. Turner, J. Baldwin, 1991 .

The emzymatic ring expansion of penicillins to cephalosporins : side chain specificity

C. Schofield, M. Crabbe, J. Baldwin, 1987 .

Conversion of 17O/18O labelled δ-(L-α-aminoadlpyl)-L-cysteinyl-D-valine to 17O/18O labelled isopenicillin n in a cell-free extract of . A study by 17O-NMR spectroscopy and mass spectrometry

Robert L. White, R. Aplin, L. Field, 1983 .

The ring opening of aziridine-2-carboxylate esters with organometallic reagents

C. Schofield, J. Baldwin, J. Sweeney, 1989 .

APPLICATIONS OF RADICAL ADDITION REACTIONS TO THE SYNTHESIS OF A C-GLUCOSIDE AND A FUNCTIONALIZED AMINO ACID

J. Baldwin, A. Basak, R. Adlington, 1983 .

Stereospecific Synthesis of Chlamydocin

J. Baldwin, V. Patel, R. Adlington, 1993 .

RETRACTED: Biomimetic approach to Galbulimina type I alkaloids

J. Baldwin, K. Tchabanenko, R. Adlington, 2005 .

Biomimetic total synthesis of (+)-himbacine.

A. Cowley, J. Baldwin, K. Tchabanenko, 2005, Organic letters.

NOVEL SYNTHESES OF 3‐METHYLENEAZETIDIN‐2‐ONE DERIVATIVES AND RELATED SYSTEMS

A. Barrett, M. J. Betts, R. Adlington, 1981 .

Studies towards the biomimetic synthesis of the nonadrides CP-225,917 and CP-263,114

A. Mayweg, F. Roussi, J. Baldwin, 2001 .

Studies Towards the Synthesis of Lindenene: Unexpected Stereochemical Outcome of an Intramolecular Cyclopropanation Reaction and Synthesis of (.+-.)-epi-Lindenene and (.+-.)-iso-Lindenene.

A. Mayweg, J. Baldwin, R. Adlington, 2008 .

Carbocyclic ring expansion reactions via radical chain processes. Part II.

J. Robertson, J. Baldwin, R. Adlington, 1991 .

Radical dearomatising spirocyclisations onto the C-2 position of benzofuran and indole

J. Baldwin, K. Tchabanenko, R. Adlington, 2004 .

Concise syntheses of 3-methylenetetrahydrofuran-2-one derivatives and related systems

A. Barrett, R. Adlington, 1982 .

Formation of novel unsaturated side chain penicillins with isopenicillin N synthase

M. Bradley, J. Baldwin, R. Adlington, 1990 .

Isopenicillin N synthase mediates thiolate oxidation to sulfenate in a depsipeptide substrate analogue: implications for oxygen binding and a link to nitrile hydratase?

P. Rutledge, I. Clifton, J. Baldwin, 2008, Journal of the American Chemical Society.

A radical route to 2(S)-4-exomethylene proline

S. Mantell, R. Adlington, 1992 .

The crystal structure of an isopenicillin N synthase complex with an ethereal substrate analogue reveals water in the oxygen binding site

P. Rutledge, I. Clifton, J. Baldwin, 2013, FEBS letters.

Penicillin biosynthesis. Dual pathways from a modified substrate

N. B. Green, L. Field, J. Baldwin, 1983 .