M. Gaunt

发表

Enantioselective catalytic intramolecular cyclopropanation using modified cinchona alkaloid organocatalysts.

S. Ley, D. Owen, Stephen C. Smith, 2006, Angewandte Chemie.

Diastereoselective C–H carbonylative annulation of aliphatic amines: a rapid route to functionalized γ-lactams† †Electronic supplementary information (ESI) available: Experimental procedures, characterization data and kinetic details. CCDC 1850700–1850701. For ESI and crystallographic data in CIF or

Zhuang Mao Png, Jaime R. Cabrera‐Pardo, Jorge Peiró Cadahía, 2018, Chemical science.

Recent developments in natural product synthesis using metal-catalysed C-H bond functionalisation.

M. Gaunt, F. O’Hara, L. McMurray, 2011, Chemical Society reviews.

Palladium(II)-catalyzed C-H bond arylation of electron-deficient arenes at room temperature.

B. Collins, M. Tredwell, C. Johansson, 2011, Angewandte Chemie.

Synthesis of rhazinicine by a metal-catalyzed C-H bond functionalization strategy.

R. Hatley, M. Gaunt, E. M. Beck, 2008, Angewandte Chemie.

Gram-scale enantioselective formal synthesis of morphine through an ortho-para oxidative phenolic coupling strategy.

Robert J. Phipps, R. D. Pace, M. Gaunt, 2014, Angewandte Chemie.

Enantioselective organocatalysis.

A. McNally, C. Johansson, M. Gaunt, 2007, Drug discovery today.

Multicomponent alkene azidoarylation by anion-mediated dual catalysis

M. Gaunt, Ala Bunescu, Yusra Abdelhamid, 2021, Nature.

A Class of N–O-Type Oxidants To Access High-Valent Palladium Species

M. Nappi, M. Gaunt, 2018, Organometallics.

A highly para-selective copper(II)-catalyzed direct arylation of aniline and phenol derivatives.

Robert J. Phipps, Jochen R. Brandt, M. Gaunt, 2011, Angewandte Chemie.

Copper(II)-catalyzed meta-selective direct arylation of α-aryl carbonyl compounds.

Robert J. Phipps, M. Gaunt, Michael L. Cooke, 2011, Angewandte Chemie.

Oxidative Pd(II)-catalyzed C-H bond amination to carbazole at ambient temperature.

C. Johansson, M. Gaunt, E. M. Beck, 2008, Journal of the American Chemical Society.

Palladium-Catalyzed C(sp3)–H Bond Functionalization of Aliphatic Amines

Chuan He, M. Gaunt, W. Whitehurst, 2019, Chem.

Visible light-mediated radical fluoromethylation via halogen atom transfer activation of fluoroiodomethane

M. Gaunt, Roopender Kumar, Patrick J Deneny, 2021, Chemical science.

Visible-light mediated carbonyl trifluoromethylative amination as a practical method for the synthesis of β-trifluoromethyl tertiary alkylamines†

M. Gaunt, Kavoos Kolahdouzan, Roopender Kumar, 2020, Chemical science.

Carboxylate-Assisted Oxidative Addition to Aminoalkyl PdII Complexes: C(sp3 )-H Arylation of Alkylamines by Distinct PdII /PdIV Pathway.

Gary N. Hermann, M. Gaunt, William G Whitehurst, 2019, Angewandte Chemie.

Carboxylate‐Assisted Oxidative Addition to Aminoalkyl Pd II Complexes: C(sp 3 )−H Arylation of Alkylamines by Distinct Pd II /Pd IV Pathway

Gary N. Hermann, M. Gaunt, William G Whitehurst, 2019, Angewandte Chemie.

Novel anti-Markovnikov regioselectivity in the Wacker reaction of styrenes.

Joseph A. Wright, Joseph A Wright, M. Gaunt, 2006, Chemistry.

A steric tethering approach enables palladium-catalysed C-H activation of primary amino alcohols.

M. Gaunt, D. Pla, V. Domingo, 2015, Nature chemistry.

Organocatalytic C-H bond arylation of aldehydes to bis-heteroaryl ketones.

A. McNally, M. Gaunt, Q. Toh, 2013, Journal of the American Chemical Society.

Cu(II)-catalyzed direct and site-selective arylation of indoles under mild conditions.

Robert J. Phipps, N. Grimster, M. Gaunt, 2008, Journal of the American Chemical Society.

Copper-catalyzed arylative Meyer-Schuster rearrangement of propargylic alcohols to complex enones using diaryliodonium salts.

B. Collins, M. Suero, M. Gaunt, 2013, Angewandte Chemie.

Selective Chemical Functionalization at N6-Methyladenosine Residues in DNA Enabled by Visible-Light-Mediated Photoredox Catalysis

S. Balasubramanian, M. Nappi, M. Gaunt, 2020, Journal of the American Chemical Society.

The α-tertiary amine motif drives remarkable selectivity for Pd-catalyzed carbonylation of β-methylene C–H bonds† †Electronic supplementary information (ESI) available: Experimental procedures, characterization data and kinetic details. CCDC 1570476. For ESI and crystallographic data in CIF or other

M. Gaunt, Kirsten F Hogg, A. Trowbridge, 2017, Chemical science.

Ligand-Enabled Catalytic C-H Arylation of Aliphatic Amines by a Four-Membered-Ring Cyclopalladation Pathway.

Chuan He, M. Gaunt, 2015, Angewandte Chemie.

Palladium-catalyzed intermolecular alkenylation of indoles by solvent-controlled regioselective C-H functionalization.

N. Grimster, M. Gaunt, C. Godfrey, 2005, Angewandte Chemie.

Synthesis of the C-1-C-28 ABCD unit of spongistatin 1.

S. Ley, P. Orsini, Alan S. Jessiman, 2003, Organic letters.

Copper-catalyzed alkene arylation with diaryliodonium salts.

Robert J. Phipps, M. Gaunt, L. McMurray, 2012, Journal of the American Chemical Society.

Enantioselective α-arylation of N-acyloxazolidinones with copper(II)-bisoxazoline catalysts and diaryliodonium salts.

Alice E. Williamson, M. Gaunt, A. Bigot, 2011, Journal of the American Chemical Society.

A Meta-Selective Copper-Catalyzed C–H Bond Arylation

Robert J. Phipps, M. Gaunt, 2009, Science.

Mild aerobic oxidative palladium (II) catalyzed C-H bond functionalization: regioselective and switchable C-H alkenylation and annulation of pyrroles.

N. Grimster, R. Hatley, M. Gaunt, 2006, Journal of the American Chemical Society.

A general catalytic β-C–H carbonylation of aliphatic amines to β-lactams

Adam P Smalley, M. Gaunt, Ben G. N. Chappell, 2016, Science.

Pd-catalyzed C-H bond functionalization on the indole and pyrrole nucleus.

M. Gaunt, E. M. Beck, 2010, Topics in current chemistry.

Cobalt-catalysed C–H carbonylative cyclisation of aliphatic amides† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c6sc05581h Click here for additional data file.

M. Gaunt, P. Williamson, Alicia Galván, 2017, Chemical science.

A protein functionalization platform based on selective reactions at methionine residues

Jennifer E. Nelson, Marcos Suero, Michael T. Taylor, 2018, Nature.

A general carbonyl alkylative amination for tertiary amine synthesis facilitated by visible light

M. Gaunt, Roopender Kumar, William G Whitehurst, 2020, Nature.

Evidence that the availability of an allylic hydrogen governs the regioselectivity of the Wacker oxidation.

M. Gaunt, J. Spencer, J. Yu, 2001, Chemical communications.

Copper-catalyzed intramolecular electrophilic carbofunctionalization of allylic amides.

N. Bremeyer, M. Gaunt, Elise Cahard, 2013, Angewandte Chemie.

Derailing the Wacker oxidation: development of a palladium-catalyzed amidation reaction.

M. Gaunt, J. Spencer, 2001, Organic letters.

Rapid syntheses of (-)-FR901483 and (+)-TAN1251C enabled by complexity-generating photocatalytic olefin hydroaminoalkylation.

Dominik Reich, M. Gaunt, A. Trowbridge, 2020, Angewandte Chemie.

Rapid Syntheses of (−)‐FR901483 and (+)‐TAN1251C Enabled by Complexity‐Generating Photocatalytic Olefin Hydroaminoalkylation

Dominik Reich, M. Gaunt, A. Trowbridge, 2019, Angewandte Chemie.

Modular Photocatalytic Synthesis of α-Trialkyl-α-Tertiary Amines.

M. Gaunt, J. Henry Blackwell, Georgia R Harris, 2021, Journal of the American Chemical Society.

Selective Reductive Elimination at Alkyl Palladium(IV) by Dissociative Ligand Ionization: Catalytic C(sp3 )-H Amination to Azetidines.

Chuan He, M. Nappi, M. Gaunt, 2018, Angewandte Chemie.

Recent developments in the use of catalytic asymmetric ammonium enolates in chemical synthesis.

C. Johansson, M. Gaunt, 2007, Chemical reviews.

Enantioselective organocatalytic cyclopropanation via ammonium ylides.

S. Ley, C. Papageorgiou, M. Gaunt, 2004, Angewandte Chemie.

An intramolecular organocatalytic cyclopropanation reaction.

S. Ley, Stephen C. Smith, N. Bremeyer, 2004, Angewandte Chemie.

Organic-catalyst-mediated cyclopropanation reaction.

S. Ley, C. Papageorgiou, M. Gaunt, 2003, Angewandte Chemie.

Convenient preparation of trans-arylalkenes via palladium(II)-catalyzed isomerization of cis-arylalkenes.

M. Gaunt, J. Spencer, Jinquan Yu, 2002, The Journal of organic chemistry.

Rational Design of Benzyl-Type Protecting Groups Allows Sequential Deprotection of Hydroxyl Groups by Catalytic Hydrogenolysis

M. Gaunt, J. Spencer, Jinquan Yu, 1998 .

Palladium-catalysed C–H activation of aliphatic amines to give strained nitrogen heterocycles

Andrew McNally, B. Collins, A. McNally, 2014, Nature.

New Strategies for the Transition-Metal Catalyzed Synthesis of Aliphatic Amines.

M. Gaunt, A. Trowbridge, Scarlett M Walton, 2020, Chemical reviews.

Multicomponent synthesis of tertiary alkylamines by photocatalytic olefin-hydroaminoalkylation

Dominik Reich, M. Gaunt, A. Trowbridge, 2018, Nature.

Oxidative Pd(II)-Catalyzed C—H Bond Amination to Carbazole at Ambient Temperature.

C. Johansson, M. Gaunt, Moisés Gulías, 2009 .

Double conjugate addition of dithiols to propargylic carbonyl systems to generate protected 1,3-dicarbonyl compounds.

S. Ley, A. Hirsch, M. Gaunt, 2006, The Journal of organic chemistry.

Selective Palladium(II)-Catalyzed Carbonylation of Methylene β-C-H Bonds in Aliphatic Amines.

Jaime R. Cabrera‐Pardo, M. Nappi, M. Gaunt, 2017, Angewandte Chemie.

Amine directed Pd(II)-catalyzed C–H bond functionalization under ambient conditions

M. Gaunt, Moisés Gulías, B. Haffemayer, 2011 .

A concise and scalable strategy for the total synthesis of dictyodendrin B based on sequential C-H functionalization.

M. Gaunt, F. O’Hara, R. Snell, 2015, Angewandte Chemie.

Chemical synthesis of Aspidosperma alkaloids inspired by the reverse of the biosynthesis of the rhazinilam family of natural products.

M. Gaunt, E. M. Beck, L. McMurray, 2012, Angewandte Chemie.

Palladium-catalyzed C(sp 3 )–H activation of amines to strained nitrogen heterocycles

B. Collins, A. McNally, M. Gaunt, 2021 .

Catalytic C(sp3)–H bond activation in tertiary alkylamines

Matthew Burns, M. Nappi, M. Gaunt, 2019, Nature Chemistry.

Palladium(II)-Catalyzed C(sp3)–H Activation of N,O-Ketals towards a Method for the β-Functionalization of Ketones

M. Gaunt, Jonás Calleja, D. H. Ho, 2019, Synlett.

Selective Pd(II)-Catalyzed Carbonylation of Methylene beta-C-H Bonds in Aliphatic Amines

Jaime R. Cabrera‐Pardo, M. Nappi, M. Gaunt, 2017 .

Mechanistic Insights into the Palladium-Catalyzed Aziridination of Aliphatic Amines by C-H Activation.

Matthew J Gaunt, Adam P Smalley, M. Gaunt, 2015, Journal of the American Chemical Society.

Multicomponent linchpin couplings. Reaction of dithiane anions with terminal epoxides, epichlorohydrin, and vinyl epoxides: efficient, rapid, and stereocontrolled assembly of advanced fragments for complex molecule synthesis.

A. M. Boldi, Amos B. Smith, S. Pitram, 2003, Journal of the American Chemical Society.

Organocatalytic sigmatropic reactions: development of a [2,3] Wittig rearrangement through secondary amine catalysis.

A. McNally, M. Gaunt, B. Evans, 2006, Angewandte Chemie.

Enantioselective and Regiodivergent Copper-Catalyzed Electrophilic Arylation of Allylic Amides with Diaryliodonium Salts

M. Gaunt, M. Tissot, Elise Cahard, 2015, Journal of the American Chemical Society.

Visible-Light-Mediated Modification and Manipulation of Biomacromolecules.

M. Nappi, M. Gaunt, J. Chu, 2021, Chemical reviews.

Development of beta-keto 1,3-dithianes as versatile intermediates for organic synthesis.

S. Ley, P. Orsini, M. Gaunt, 2003, Organic & biomolecular chemistry.

Addition of dithiols to bis-ynones: development of a versatile platform for the synthesis of polyketide natural products.

S. Ley, M. Gaunt, H. Sneddon, 2003, Organic letters.

Callipeltosides A, B and C: Total Syntheses and Structural Confirmation

Richard A Booth, Steven V Ley, James R Frost, 2015, Chemistry.

Dithiane additions to vinyl epoxides: steric control over the SN2 and SN2' manifolds.

S. Kozmin, Amos B. Smith, S. Pitram, 2002, Journal of the American Chemical Society.

A counteranion triggered arylation strategy using diaryliodonium fluorides† †Electronic supplementary information (ESI) available: Experimental data for all new compounds and procedures. See DOI: 10.1039/c4sc02856b Click here for additional data file. Click here for additional data file.

Abraham Mendoza, A. McNally, M. Gaunt, 2014, Chemical science.

An enantioselective organocatalytic oxidative dearomatization strategy.

R. D. Pace, M. Gaunt, F. O’Hara, 2008, Journal of the American Chemical Society.

Alkynes to (E)-enolates using tandem catalysis: stereoselective anti-aldol and syn-[3,3]-rearrangement reactions

N. Grimster, D. Owen, C. Green, 2010 .

Enantioselective Cu-Catalyzed Arylation of Secondary Phosphine Oxides with Diaryliodonium Salts toward the Synthesis of P-Chiral Phosphines

Robert J. Phipps, R. Beaud, M. Gaunt, 2016, Journal of the American Chemical Society.

Organic Catalyst Mediated Cyclopropanation Reaction.

S. Ley, C. Papageorgiou, M. Gaunt, 2003 .

Recent Developments in the Use of Catalytic Asymmetric Ammonium Enolates in Chemical Synthesis

C. Johansson, M. Gaunt, 2008 .

Multicomponent synthesis of α-chloro alkylboronic esters via visible-light-mediated dual catalysis

Bo Li, M. Gaunt, Ala Bunescu, 2022, Chem.

Mechanistic investigation into the C(sp3)–H acetoxylation of morpholinones† †Electronic supplementary information (ESI) available: Experimental procedures, characterization data and kinetic details. See DOI: 10.1039/c8sc03434f

M. Gaunt, Ben G. N. Chappell, D. Willcox, 2018, Chemical science.

Palladium-Catalyzed Enantioselective C-H Activation of Aliphatic Amines Using Chiral Anionic BINOL-Phosphoric Acid Ligands.

Adam P Smalley, M. Gaunt, J. Cuthbertson, 2017, Journal of the American Chemical Society.

Enantioselective Copper-Catalyzed Arylation-Driven Semipinacol Rearrangement of Tertiary Allylic Alcohols with Diaryliodonium Salts.

M. Gaunt, Daniel H. Lukamto, 2017, Journal of the American Chemical Society.

Cu-catalyzed cascades to carbocycles: union of diaryliodonium salts with alkenes or alkynes exploiting remote carbocations.

Michael T. Taylor, Shoubhik Das, Alicia Casitas, 2014, Journal of the American Chemical Society.

Copper-catalyzed electrophilic carbofunctionalization of alkynes to highly functionalized tetrasubstituted alkenes.

B. Collins, M. Suero, M. Gaunt, 2013, Journal of the American Chemical Society.

Catalytic enantioselective assembly of complex molecules containing embedded quaternary stereogenic centres from simple anisidine derivatives

M. Gaunt, A. Jawalekar, Rafael León, 2011 .

Organic chemistry: Metals are not the only catalysts

M. Gaunt, 2011, Nature.

Copper-Catalyzed Oxy-Alkenylation of Homoallylic Alcohols to Generate Functional syn-1,3-Diol Derivatives.

M. Gaunt, Dean Holt, 2015, Angewandte Chemie.

Preferential hydrogenolysis of NAP esters provides a new orthogonal protecting group strategy for carboxylic acids

C. Boschetti, M. Gaunt, J. Spencer, 1999 .

Rational Design of Benzyl-Type Protecting Groups Allows Sequential Deprotection of Hydroxyl Groups by Catalytic Hydrogenolysis

M. Gaunt, J. Spencer, Jinquan Yu, 1998 .

Thiol-Mediated α-Amino Radical Formation via Visible-Light-Activated Ion-Pair Charge-Transfer Complexes.

M. Gaunt, A. Trowbridge, Milo A Smith, 2021, Journal of the American Chemical Society.

Total synthesis of spongistatin 1: a synthetic strategy exploiting its latent pseudo-symmetry.

S. Ley, P. Orsini, Alan S. Jessiman, 2005, Angewandte Chemie.

Copper-catalyzed carboarylation of alkynes via vinyl cations.

M. Suero, M. Gaunt, Wen-Hua Xu, 2013, Journal of the American Chemical Society.

Synthesis and Reactivity of Stable Alkyl-Pd(IV) Complexes Relevant to Monodentate N-directed C(sp3)-H Functionalization Processes.

M. Gaunt, William G Whitehurst, 2020, Journal of the American Chemical Society.

Streamlined Synthesis of C(sp3)-Rich N-Heterospirocycles Enabled by Visible-Light-Mediated Photocatalysis.

M. Gaunt, D. Willcox, Yongjoo Kim, 2019, Journal of the American Chemical Society.

A practical and efficient synthesis of the C-16-C-28 spiroketal fragment (CD) of the spongistatins.

S. Ley, Huw R. Tanner, M. Gaunt, 2003, Organic letters.

Multicomponent synthesis of tertiary alkylamines by photocatalytic olefin-hydroaminoalkylation

Dominik Reich, M. Gaunt, A. Trowbridge, 2018, Nature.

The Effect of Chemical Representation on Active Machine Learning Towards Closed-Loop Optimization

Lucy J. Colwell, A. Lapkin, M. Gaunt, 2022, Reaction Chemistry & Engineering.

Pd(II)-Catalyzed Enantioselective C(sp3)–H Arylation of Cyclopropanes and Cyclobutanes Guided by Tertiary Alkylamines

M. Gaunt, Javier Miró, Jesus Rodrigalvarez, 2022, Journal of the American Chemical Society.

A Chiral Amine Transfer Approach to the Photocatalytic Asymmetric Synthesis of α-Trialkyl-α-tertiary Amines

M. Gaunt, A. Trowbridge, Georgia R Harris, 2023, Organic letters.

C(sp3)–C(sp3) coupling of non-activated alkyl-iodides with electron-deficient alkenes via visible-light/silane-mediated alkyl-radical formation

M. Gaunt, Roopender Kumar, Andrew S. Lister, 2022, Chemical Science.

Visible-Light-Mediated Carbonyl Alkylative Amination to All-Alkyl α-Tertiary Amino Acid Derivatives.

M. Gaunt, Roopender Kumar, J. Blackwell, 2021, Journal of the American Chemical Society.

Rapid Generation of Complex Molecular Architectures by a Catalytic Enantioselective Dearomatization Strategy

Alice E. Williamson, M. Gaunt, J. Cuthbertson, 2015, Synlett.

Copper-catalyzed carboarylation of alkynes via vinyl cations.

M. Suero, M. Gaunt, Wen-Hua Xu, 2013, Journal of the American Chemical Society.

Oxidative Pd(II)-catalyzed C-H bond amination to carbazole at ambient temperature.

C. Johansson, M. Gaunt, E. M. Beck, 2008, Journal of the American Chemical Society.

Scalable Palladium-Catalyzed C(sp3)–H Carbonylation of Alkylamines in Batch and Continuous Flow

A. Lapkin, J. Zakrzewski, P. Yaseneva, 2023, Organic Process Research & Development.

Gram-scale enantioselective formal synthesis of morphine through an ortho-para oxidative phenolic coupling strategy.

Robert J. Phipps, M. Gaunt, C. Lucas, 2014, Angewandte Chemie.

Palladium-catalyzed intermolecular alkenylation of indoles by solvent-controlled regioselective C-H functionalization.

N. Grimster, M. Gaunt, C. Godfrey, 2005, Angewandte Chemie.

Multicomponent Synthesis of α-Branched Amines via a Zinc-Mediated Carbonyl Alkylative Amination Reaction

M. Gaunt, Roopender Kumar, Nils J Flodén, 2024, Journal of the American Chemical Society.

The total synthesis of K-252c (staurosporinone) via a sequential C–H functionalisation strategy

M. Gaunt, R. E. Gilligan, J. C. Fox, 2016, Chemical science.

Multicomponent synthesis of tertiary alkylamines by photocatalytic olefin-hydroaminoalkylation

Dominik Reich, M. Gaunt, A. Trowbridge, 2018, Nature.

A general catalytic β-C–H carbonylation of aliphatic amines to β-lactams

Adam P Smalley, M. Gaunt, Ben G. N. Chappell, 2016, Science.

Organocatalytic C-H bond arylation of aldehydes to bis-heteroaryl ketones.

A. McNally, M. Gaunt, Q. Toh, 2013, Journal of the American Chemical Society.

Continuous‐Flow Synthesis and Derivatization of Aziridines through Palladium‐Catalyzed C(sp3)−H Activation

Matthew J Gaunt, Alexei A Lapkin, Mikhail A Kabeshov, 2016, Angewandte Chemie.