P. Porubsky

发表

Overcoming product inhibition in catalysis of the intramolecular Schmidt reaction.

J. Aubé, C. Fehl, Hashim F. Motiwala, 2013, Journal of the American Chemical Society.

p-dimethylaminocinnamaldehyde derivatization for colorimetric detection and HPLC-UV/vis-MS/MS identification of indoles.

T. Williams, E. Scott, P. Porubsky, 2008, Archives of biochemistry and biophysics.

Evaluating p97 Inhibitor Analogues for Potency against p97–p37 and p97–Npl4–Ufd1 Complexes

Henry J. Lin, T. Chou, F. Schoenen, 2016, ChemMedChem.

3-Substituted Biquinolinium Inhibitors of AraC Family Transcriptional Activator VirF from S. flexneri Obtained Through In Situ Chemical Ionization of 3,4-Disubstituted Dihydroquinolines.

Benjamin Neuenswander, J. Aubé, S. Egan, 2014, RSC advances.

Effect of C-2 substitution on the stability of non-traditional cephalosporins in mouse plasma

C. Nathan, M. Zimmerman, J. Aubé, 2019, The Journal of Antibiotics.

Identification of Potent and Selective Inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PfM18AAP) of Human Malaria via High-Throughput Screening

J. Dalton, T. Spicer, P. Ghosh, 2014, Journal of biomolecular screening.

Facile (triazolyl)methylation of MACOS-derived benzofused sultams utilizing ROMP-derived OTP reagents.

F. Ullah, G. Lushington, Benjamin Neuenswander, 2012, ACS combinatorial science.

Synthesis of amino-benzothiaoxazepine-1,1-dioxides utilizing a microwave-assisted, S(N)Ar protocol.

F. Ullah, G. Lushington, Benjamin Neuenswander, 2011, ACS combinatorial science.

Triazole-containing isothiazolidine 1,1-dioxide library synthesis: one-pot, multi-component protocols for small molecular probe discovery.

G. Lushington, Benjamin Neuenswander, P. Hanson, 2011, ACS combinatorial science.

Automated synthesis of a library of triazolated 1,2,5-thiadiazepane 1,1-dioxides via a double aza-Michael strategy.

F. Ullah, G. Lushington, Benjamin Neuenswander, 2012, ACS combinatorial science.

Novel Cephalosporins Selectively Active on Nonreplicating Mycobacterium tuberculosis

C. Nathan, M. Zimmerman, J. Aubé, 2016, Journal of medicinal chemistry.

A Small Molecule Inhibitor of the MITF Molecular Pathway

Patrick W. Faloon, Carrie M. Mosher, S. Schreiber, 2014 .

Solution-phase synthesis of a diverse library of benzisoxazoles utilizing the [3 + 2] cycloaddition of in situ-generated nitrile oxides and arynes.

G. Lushington, R. Larock, F. Shi, 2013, ACS combinatorial science.

Synthesis of an Isoindoline-Annulated, Tricyclic Sultam Library via Microwave-Assisted, Continuous-Flow Organic Synthesis (MACOS).

F. Ullah, G. Lushington, Benjamin Neuenswander, 2012, Synthesis.

Effect of C-2 substitution on the stability of non-traditional cephalosporins in mouse plasma

C. Nathan, M. Zimmerman, J. Aubé, 2019, The Journal of Antibiotics.

Exploring chemical diversity via a modular reaction pairing strategy

G. Lushington, Benjamin Neuenswander, P. Hanson, 2012, Beilstein journal of organic chemistry.

Synthesis of a unique isoindoline/tetrahydroisoquinoline-based tricyclic sultam library utilizing a Heck-aza-Michael strategy.

F. Ullah, G. Lushington, Benjamin Neuenswander, 2012, ACS combinatorial science.

Small Molecules Targeting the Mitochondrial Permeability Transition

M. Jackson, T. Chung, D. Bourdette, 2015 .

Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways

Steven J Brown, R. Deshaies, T. Chou, 2011, Proceedings of the National Academy of Sciences.

Human Cytochrome P450 2E1 Structures with Fatty Acid Analogs Reveal a Previously Unobserved Binding Mode*

K. Battaile, E. Scott, P. Porubsky, 2010, The Journal of Biological Chemistry.

Structures of Human Steroidogenic Cytochrome P450 17A1 with Substrates*

E. Scott, P. Porubsky, N. DeVore, 2014, The Journal of Biological Chemistry.

Lifting the Mask: Identification of New Small Molecule Inhibitors of Uropathogenic Escherichia coli Group 2 Capsule Biogenesis

Brooks E. Maki, Nichole A. Tower, Carlos C. Goller, 2014, PloS one.

Structures of Human Cytochrome P-450 2E1

E. Scott, Emily E. Scott, P. Porubsky, 2008, Journal of Biological Chemistry.

Structure of the Human Lung Cytochrome P450 2A13*

C. Stout, G. Lushington, E. Scott, 2007, Journal of Biological Chemistry.

Selective, reversible inhibitors of the AAA ATPase p97

Patrick Porubsky, Jeffrey Aubé, Kevin J. Frankowski, 2013 .

uinolinium inhibitors of AraC family transcriptional activator VirF from S . fl exneri obtained through in situ chemical ionization of 3 , 4-disubstituted dihydroquinolines †

Benjamin Neuenswander, S. Egan, Prashi Jain, 2014 .

Overcoming product inhibition in catalysis of the intramolecular Schmidt reaction.

J. Aubé, C. Fehl, E. Hirt, 2013, Journal of the American Chemical Society.

Inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase

Nichole A. Tower, J. Dalton, T. Spicer, 2014 .

Evaluating p97 Inhibitor Analogues for Potency against p97–p37 and p97–Npl4–Ufd1 Complexes

Henry J. Lin, T. Chou, F. Schoenen, 2016, ChemMedChem.