Ai M. Fletcher

发表

Asymmetric synthesis of (-)-martinellic acid.

James A. Lee, J. E. Thomson, S. Davies, 2013, Organic letters.

A diastereodivergent strategy for the asymmetric syntheses of (−)-martinellic acid and (−)-4-epi-martinellic acid

James A. Lee, J. E. Thomson, S. Davies, 2013 .

An electrochemical thermometer: voltammetric measurement of temperature and its application to amperometric gas sensing.

R. Compton, S. Davies, Ai M. Fletcher, 2012, The Analyst.

Asymmetric syntheses of methyl N-Boc-2-deoxy-2-amino-l-erythroside, methyl N-Boc-2-deoxy-2-amino-d-threoside and methyl N-Boc-2,3-dideoxy-3-amino-l-arabinopyranoside

J. E. Thomson, S. Davies, P. M. Roberts, 2014 .

Concise and highly selective asymmetric synthesis of acosamine from sorbic acid

James A. Lee, J. E. Thomson, S. Davies, 2011 .

Alkylation and aldol reactions of acyl derivatives of N-1-(1′-naphthyl)ethyl-O-tert-butylhydroxylamine: asymmetric synthesis of α-alkoxy-, α-substituted-β-alkoxy- and α,β-dialkoxyaldehydes

J. E. Thomson, D. Hepworth, S. Davies, 2010 .

Syntheses of (R)-sitagliptin

J. E. Thomson, S. Davies, Ai M. Fletcher, 2015 .

Asymmetric synthesis of (−)-(R)-sitagliptin

J. E. Thomson, S. Davies, P. M. Roberts, 2012 .

Synthesis of SMT022357 enantiomers and in vivo evaluation in a Duchenne muscular dystrophy mouse model

J. E. Thomson, G. Wynne, K. Davies, 2020, Tetrahedron.

The asymmetric synthesis of (S,S)-methylphenidate hydrochloride via ring-opening of an enantiopure aziridinium intermediate with phenylmagnesium bromide

J. E. Thomson, S. Davies, P. M. Roberts, 2019, Tetrahedron.

Asymmetric synthesis of d-fagomine and its diastereoisomers

J. E. Thomson, S. Davies, P. M. Roberts, 2018, Tetrahedron.

Structural Revision of the Hancock Alkaloid (-)-Galipeine.

J. E. Thomson, S. Davies, P. M. Roberts, 2017, The Journal of organic chemistry.

Asymmetric Syntheses of 3-Deoxy-3-aminosphingoid Bases: Approaches Based on Parallel Kinetic Resolution and Double Asymmetric Induction.

J. E. Thomson, S. Davies, P. M. Roberts, 2017, The Journal of organic chemistry.

Trading N and O. Part 3: Synthesis of 1,2,3,4-tetrahydroisoquinolines from α-hydroxy-β-amino esters

J. E. Thomson, S. Davies, P. M. Roberts, 2016 .

The asymmetric synthesis of enantiopure C(5)-substituted transpentacins via diastereoselective conjugate additions to a β′-amino-α,β-unsaturated ester

J. E. Thomson, S. Davies, P. M. Roberts, 2016 .

Asymmetric synthesis of N,O-diacetyl-3-epi-xestoaminol C: structure and absolute configuration confirmation of 3-epi-xestoaminol C

J. E. Thomson, S. Davies, P. M. Roberts, 2016 .

Asymmetric syntheses of the methyl 3-deoxy-3-amino-glycosides of d-glycero-l-gulo-heptose, d-glycero-d-galacto-heptose, d-glycero-l-allo-heptose and d-glycero-d-allo-heptose

James A. Lee, J. E. Thomson, S. Davies, 2016 .

Asymmetric syntheses of the 1-hydroxymethyl-2-hydroxy substituted pyrrolizidines (−)-macronecine, (−)-petasinecine, (−)-1-epi-macronecine, (+)-1-epi-petasinecine and (+)-2-epi-rosmarinecine

J. E. Thomson, S. Davies, P. M. Roberts, 2016 .

Asymmetric Synthesis of Substituted anti-β-Fluorophenylalanines.

J. E. Thomson, S. Davies, P. M. Roberts, 2015, Organic letters.

Asymmetric syntheses of polysubstituted homoprolines and homoprolinols

James A. Lee, J. E. Thomson, S. Davies, 2015 .

Concise total asymmetric syntheses of (−)-fagomine, two of its epimers, and two seven-membered ring congeners

J. E. Thomson, David J. Klauber, S. Davies, 2015 .

Asymmetric syntheses of (-)-3-epi-Fagomine, (2R,3S,4R)-dihydroxypipecolic acid, and several polyhydroxylated homopipecolic acids.

J. E. Thomson, David J. Klauber, S. Davies, 2014, The Journal of organic chemistry.

Asymmetric syntheses of 2,5-dideoxy-2,5-imino-d-glucitol [(+)-DGDP] and 1,2,5-trideoxy-1-amino-2,5-imino-d-glucitol [(+)-ADGDP]

J. E. Thomson, S. Davies, P. M. Roberts, 2014 .

Diastereoselective Ireland-Claisen rearrangements of substituted allyl β-amino esters: applications in the asymmetric synthesis of C(5)-substituted transpentacins.

James A. Lee, J. E. Thomson, S. Davies, 2014, Organic & biomolecular chemistry.

Asymmetric syntheses of (-)-1-deoxymannojirimycin and (+)-1-deoxyallonojirimycin via a ring-expansion approach.

J. E. Thomson, S. Davies, P. M. Roberts, 2013, Organic letters.

Asymmetric syntheses of enantiopure C(5)-substituted transpentacins via diastereoselective Ireland-Claisen rearrangements.

J. E. Thomson, S. Davies, P. M. Roberts, 2013, Chemical communications.

Asymmetric syntheses of APTO and AETD: the β-amino acid fragments within microsclerodermins C, D, and E.

James A. Lee, J. E. Thomson, S. Davies, 2013, The Journal of organic chemistry.

Trading N and O: asymmetric syntheses of β-hydroxy-α-amino acids via α-hydroxy-β-amino esters

James A. Lee, J. E. Thomson, S. Davies, 2013 .

Short asymmetric syntheses of sphinganine [(2S,3R)-2-aminooctadecane-1,3-diol] and its C(2)-epimer

J. E. Thomson, S. Davies, P. M. Roberts, 2021 .

Asymmetric synthesis of β-fluoroaryl-β-amino acids

J. E. Thomson, S. Davies, P. M. Roberts, 2012 .

Probing Competitive and Co-operative Hydroxyl and Ammonium Hydrogen-Bonding Directed Epoxidations.

James A. Lee, J. E. Thomson, A. Russell, 2017, The Journal of organic chemistry.

Isolation, structural identification, synthesis, and pharmacological profiling of 1,2-trans-dihydro-1,2-diol metabolites of the utrophin modulator ezutromid.

G. Wynne, K. Davies, M. Chatzopoulou, 2019, Journal of medicinal chemistry.

Asymmetric syntheses of (−)-isoretronecanol and (−)-trachelantamidine

J. E. Thomson, S. Davies, P. M. Roberts, 2014 .

Pinacolatoboron fluoride (pinBF) is an efficient fluoride transfer agent for diastereoselective synthesis of benzylic fluorides

James A. Lee, J. E. Thomson, S. Davies, 2015 .

One-pot conversions of olefins to cyclic carbonates and secondary allylic and homoallylic amines to cyclic carbamates.

James A. Lee, J. E. Thomson, S. Davies, 2010, The Journal of organic chemistry.

The Hancock Alkaloids Angustureine, Cuspareine, Galipinine, and Galipeine: A Review of their Isolation, Synthesis, and Spectroscopic Data

J. E. Thomson, S. Davies, P. M. Roberts, 2019, European Journal of Organic Chemistry.

The conjugate addition of enantiomerically pure lithium amides as chiral ammonia equivalents part II: 2005−2011

J. E. Thomson, S. Davies, P. M. Roberts, 2012 .

Stereochemical aspects of nucleophilic addition reactions to alkoxycarbene cations of the iron chiral auxiliary [(η5-C5H5)Fe(CO)(PPh3)]

J. E. Thomson, S. Davies, Ai M. Fletcher, 2013 .

Asymmetric synthesis of Sedum alkaloids via lithium amide conjugate addition

S. Davies, Andrew D. Smith, P. M. Roberts, 2009 .

Direct asymmetric syntheses of chiral aldehydes and ketones via N-acyl chiral auxiliary derivatives including chiral Weinreb amide equivalents.

J. E. Thomson, S. Davies, Ai M. Fletcher, 2013, Chemical communications.

Asymmetric synthesis of piperidines and octahydroindolizines using a one-pot ring-closure/N-debenzylation procedure

James A. Lee, J. E. Thomson, A. Russell, 2011 .

Asymmetric Syntheses of (+)-Preussin B, the C(2)-Epimer of (-)-Preussin B, and 3-Deoxy-(+)-preussin B.

J. E. Thomson, S. Davies, P. M. Roberts, 2016, The Journal of organic chemistry.

Trading N and O. Part 4: Asymmetric synthesis of syn-β-substituted-α-amino acids

J. E. Thomson, S. Davies, P. M. Roberts, 2018, Tetrahedron.

Enantiospecific stereodivergent synthesis of trans- and cis-N(2),3-dimethyl-4-phenyl-1,2,3,4-tetrahydroisoquinolines.

J. E. Thomson, S. Davies, P. M. Roberts, 2010, Chemistry, an Asian journal.

Stereoselective syntheses of substituted succinic acid derivatives of the iron chiral auxiliary [(η5-C5H5)Fe(CO)(PPh3)]

J. E. Thomson, S. Davies, G. Bodwell, 2014 .

Lithium Amides as Homochiral Ammonia Equivalents for Conjugate Additions to α,β‐Unsaturated Esters: Asymmetric Synthesis of (S)‐β‐Leucine

S. Davies, P. M. Roberts, Ai M. Fletcher, 2011 .

Ammonium-directed olefinic epoxidation: kinetic and mechanistic insights.

James A. Lee, J. E. Thomson, R. Compton, 2012, The Journal of organic chemistry.

Pyrrolizidines, indolizidines and quinolizidines via a double reductive cyclisation protocol: concise asymmetric syntheses of (+)-trachelanthamidine, (+)-tashiromine and (+)-epilupinine

J. E. Thomson, S. Davies, P. M. Roberts, 2016 .

Asymmetric and enantiospecific syntheses of 1-hydroxymethyl pyrrolizidine alkaloids

J. E. Thomson, S. Davies, Ai M. Fletcher, 2014 .

Asymmetric syntheses of nakinadine D, nakinadine E, and nakinadine F: confirmation of their relative (RS,SR)-configurations and proposal of their absolute (2S,3R)-configurations.

J. E. Thomson, S. Davies, P. M. Roberts, 2015, The Journal of organic chemistry.

Small molecule colorimetric probes for specific detection of human arylamine N-acetyltransferase 1, a potential breast cancer biomarker.

Akane Kawamura, Edith Sim, James Robinson, 2010, Journal of the American Chemical Society.

Asymmetric synthesis of the allocolchicinoid natural product N-acetylcolchinol methyl ether (suhailamine), solid state and solution phase conformational analysis

J. E. Thomson, S. Davies, P. M. Roberts, 2019, Tetrahedron.

Mutual kinetic resolution: probing enantiorecognition phenomena and screening for kinetic resolution with racemic reagents.

J. E. Thomson, S. Davies, P. M. Roberts, 2021, Organic & biomolecular chemistry.

Trading N and O . Part 2: Exploiting aziridinium intermediates for the synthesis of β-hydroxy-α-amino acids

J. E. Thomson, S. Davies, P. M. Roberts, 2014 .

Asymmetric synthesis of (−)-(1R,7aS)-absouline

J. E. Thomson, S. Davies, P. M. Roberts, 2013 .

Asymmetric syntheses of (−)-hastanecine, (−)-turneforcidine and (−)-platynecine

J. E. Thomson, S. Davies, P. M. Roberts, 2016 .

(-)-(2S,3R,Z)-Nakinadine A: first asymmetric synthesis and absolute configuration assignment.

J. E. Thomson, S. Davies, P. M. Roberts, 2014, Organic letters.

Doubly diastereoselective conjugate addition of enantiopure lithium amides to enantiopure N-enoyl oxazolidin-2-ones: a mechanistic probe

J. E. Thomson, S. Davies, Andrew D. Smith, 2010 .

SuperQuat chiral auxiliaries: design, synthesis, and utility.

J. E. Thomson, S. Davies, P. M. Roberts, 2019, Organic & biomolecular chemistry.

Asymmetric syntheses of the methyl glycosides of 2-deoxy-2-aminohexoses: d-allosamine, d-mannosamine, d-idosamine and d-talosamine

James A. Lee, J. E. Thomson, S. Davies, 2014 .

Asymmetric syntheses of fagomine and its stereoisomers

J. E. Thomson, S. Davies, P. M. Roberts, 2019, Tetrahedron.

Polysubstituted piperidines via iodolactonization: application to the asymmetric synthesis of (+)-pseudodistomin D.

James A. Lee, J. E. Thomson, A. Russell, 2012, Organic letters.

Asymmetric Synthesis of Pyrrolizidines, Indolizidines and Quinolizidines via a Double Reductive Cyclisation Protocol

J. E. Thomson, S. Davies, P. M. Roberts, 2017, Synlett.

Synthesis of (-)-Conduramine A1, (-)-Conduramine A2 and (-)-Conduramine E2 in Six Steps from Cyclohexa-1,4-diene.

J. E. Thomson, S. Davies, P. M. Roberts, 2019, Organic letters.

N-Acetylcolchinol Methyl Ether (a Natural Product); Suhailamine (a Phantom Natural Product).

J. E. Thomson, S. Davies, P. M. Roberts, 2019, Journal of natural products.

The Hancock Alkaloids (-)-Cuspareine, (-)-Galipinine, (-)-Galipeine, and (-)-Angustureine: Asymmetric Syntheses and Corrected 1H and 13C NMR Data.

J. E. Thomson, S. Davies, P. M. Roberts, 2018, Journal of natural products.

Discussion Addendum for: Lithium Amides as Homochiral Ammonia Equivalents for Conjugate Additions to α,β‐Unsaturated Esters: Asymmetric Synthesis of ( S )‐ β‐Leucine

J. E. Thomson, S. Davies, P. M. Roberts, 2019 .

Asymmetric Syntheses of (2 R,3 S)-3-Hydroxyproline and (2 S,3 S)-3-Hydroxyproline.

J. E. Thomson, S. Davies, P. M. Roberts, 2018, Organic letters.

The asymmetric syntheses of pyrrolizidines, indolizidines and quinolizidines via two sequential tandem ring-closure/N-debenzylation processes.

J. E. Thomson, S. Davies, P. M. Roberts, 2014, Organic and biomolecular chemistry.

The Asymmetric Syntheses of Pyrrolizidines, Indolizidines and Quinolizidines via Two Sequential Tandem Ring‐Closure/N‐Debenzylation Processes.

J. E. Thomson, S. Davies, P. M. Roberts, 2015 .

An efficient asymmetric synthesis of (-)-lupinine.

J. E. Thomson, S. Davies, P. M. Roberts, 2014, Chemical communications.

Stereoselective Ammonium-Directed Epoxidation in the Asymmetric Syntheses of Dihydroconduramines (–)-A-2, (–)-B-2, (–)-C-3 and (+)-F-3

J. E. Thomson, S. Davies, P. M. Roberts, 2017, Synthesis.

(-)-Pseudodistomin E: First Asymmetric Synthesis and Absolute Configuration Assignment.

J. E. Thomson, S. Davies, P. M. Roberts, 2017, Organic letters.

Asymmetric Synthesis of the Tetraponerine Alkaloids.

J. E. Thomson, S. Davies, P. M. Roberts, 2017, The Journal of organic chemistry.

Syntheses of Dihydroconduramines (±)-B-1, (±)-E-1, and (±)-F-1 via Diastereoselective Epoxidation of N-Protected 4-Aminocyclohex-2-en-1-ols.

James A. Lee, J. E. Thomson, A. Russell, 2015, The Journal of organic chemistry.

Epoxidation of trans-4-Aminocyclohex-2-en-1-ol Derivatives: Competition of Hydroxy-Directed and Ammonium-Directed Pathways*

James A. Lee, J. E. Thomson, A. Russell, 2015 .

Hydrogen bond directed epoxidation: diastereoselective olefinic oxidation of allylic alcohols and amines.

J. E. Thomson, S. Davies, Ai M. Fletcher, 2014, Organic & biomolecular chemistry.

Asymmetric syntheses of the N-terminal α-hydroxy-β-amino acid components of microginins 612, 646 and 680

J. E. Thomson, S. Davies, P. M. Roberts, 2017 .

Ammonium-directed oxidation of cyclic allylic and homoallylic amines.

James A. Lee, J. E. Thomson, A. Russell, 2009, Journal of Organic Chemistry.

Diastereoselective Ammonium-Directed Epoxidation in the Asymmetric Syntheses of Dihydroconduramines (+)-C-2, (-)-C-2, (+)-D-2, (+)-E-2, (+)-F-2, and (-)-F-2.

J. E. Thomson, S. Davies, P. M. Roberts, 2018, The Journal of organic chemistry.

Rapid Stereoselective Syntheses of Heteroarene-Fused Azacycles via Diastereoselective Conjugate Addition of Heteroaryl Substituted Lithium Amides

J. E. Thomson, S. Davies, P. M. Roberts, 2019, HETEROCYCLES.

Microgrewiapine C: Asymmetric Synthesis, Spectroscopic Data, and Configuration Assignment

S. Davies, P. M. Roberts, Ai M. Fletcher, 2022, Journal of natural products.

Synthesis and Configuration of O-Acetyl Microgrewiapine A: Phantomization of O-Acetyl 6-epi-Microgrewiapine A.

S. Davies, P. M. Roberts, Ai M. Fletcher, 2021, Journal of natural products.

Microcosamine A, Microgrewiapine A and Microgrewiapine B: three homochiral alkaloids?

S. Davies, P. M. Roberts, Ai M. Fletcher, 2021 .

Microconine [N-methyl-2-methyl-3-methoxy-6-(deca-l’,3′,5′-trienyl)piperidine, an alkaloid from Microcos paniculata]: Synthesis, stereochemistry and spectroscopic data

S. Davies, P. M. Roberts, Ai M. Fletcher, 2020 .

General Approach to Enantiopure 1-Aminopyrrolizidines: Application to the Asymmetric Synthesis of the Loline Alkaloids

S. Davies, Ai M. Fletcher, J. Thomson, 2023, Journal of Organic Chemistry.

Tuning solute redox potentials by varying the anion component of room temperature ionic liquids.

R. Compton, C. Hardacre, S. Davies, 2012, Chemical communications.