A. Francesch

发表

Isolation and first total synthesis of PM050489 and PM060184, two new marine anticancer compounds.

F. Reyes, C. Cuevas, S. Munt, 2013, Journal of the American Chemical Society.

Enzyme-labile protecting groups for the synthesis of natural products: solid-phase synthesis of thiocoraline.

Miriam Góngora-Benítez, Judit Tulla-Puche, F. Albericio, 2013, Angewandte Chemie.

New Antineoplastic Naphthohydroquinones Attached to Labdane and Rearranged Diterpene Skeletons

A. Francesch, Ángela-Patricia Hernández, A. San Feliciano, 2021, Molecules.

Stellatolides, a new cyclodepsipeptide family from the sponge Ecionemia acervus: isolation, solid-phase total synthesis, and full structural assignment of stellatolide A.

Judit Tulla-Puche, F. Albericio, F. Reyes, 2014, Journal of the American Chemical Society.

MI130004, a Novel Antibody–Drug Conjugate Combining Trastuzumab with a Molecule of Marine Origin, Shows Outstanding In Vivo Activity against HER2-Expressing Tumors

C. Galmarini, J. F. Martínez-Leal, S. Munt, 2018, Molecular Cancer Therapeutics.

Synthesis and Structure–Activity Relationship of Cytotoxic Marine Cyclodepsipeptide IB‐01212 Analogues

F. Albericio, C. Cuevas, A. Francesch, 2007, ChemMedChem.

Synthesis of Ecteinascidin 743 Analogues from Cyanosafracin B: Isolation of a Kinetically Stable Quinoneimine Tautomer of a 5‐Hydroxyindole

C. Cuevas, A. Echavarren, A. Francesch, 2006 .

Lignopurines: a new family of hybrids between cyclolignans and purines. Synthesis and biological evaluation.

F. Mollinedo, A. Francesch, A. San Feliciano, 2012, European journal of medicinal chemistry.

New 1,4-anthracenedione derivatives with fused heterocyclic rings: synthesis and biological evaluation

A. Francesch, A. Mesa-Arango, M. Castro, 2015 .

Ecteinascidin-743 (Yondelis®), Aplidin®, and Irvalec®

C. Galmarini, S. Munt, P. Avilés, 2011 .

Diazonamides C–E, new cytotoxic metabolites from the ascidian Diazona sp.

F. Reyes, C. Cuevas, R. Fernández, 2008 .

Synthesis and structure-activity relationship study of potent cytotoxic analogues of the marine alkaloid Lamellarin D.

Fernando Albericio, Andrés Francesch, Mercedes Alvarez, 2006, Journal of medicinal chemistry.

Synthesis and cytotoxic evaluation of new derivatives of the marine alkaloid variolin B.

P. Molina, C. Cuevas, A. Francesch, 2006, Journal of medicinal chemistry.

Synthesis, cytotoxicity and antiplasmodial activity of novel ent-kaurane derivatives.

A. Francesch, L. García-Fernández, Ronan Batista, 2013, European journal of medicinal chemistry.

Topoisomerase I-mediated DNA cleavage as a guide to the development of antitumor agents derived from the marine alkaloid lamellarin D: triester derivatives incorporating amino acid residues.

C. Bailly, C. Tardy, C. Cuevas, 2004, Bioorganic & medicinal chemistry.

Steric Hindrance Facilitated Synthesis of Enynes and Their Intramolecular [4 + 2] Cycloaddition with Alkynes

Juan J. González, D. Cárdenas, A. Echavarren, 1998 .

Dearomatizing anionic cyclization of N-methyl-N-benzyldi(1-naphthyl)phosphinamide: a route for access to a new class of functionalized tricyclic azaphospholes with antitumor properties

M. Serrano-Ruiz, C. Cuevas, M. Iglesias, 2012 .

Lamellarin D bioconjugates I: Synthesis and cellular internalization of PEG-derivatives.

Fernando Albericio, Andrés Francesch, Mercedes Alvarez, 2009, Bioconjugate chemistry.

Development of Yondelis (trabectedin, ET-743). A semisynthetic process solves the supply problem.

Andrés Francesch, Carmen Cuevas, C. Cuevas, 2009, Natural product reports.

Structure-activity relationship of kahalalide F synthetic analogues.

E. Giralt, F. Albericio, C. Cuevas, 2008, Journal of medicinal chemistry.

Total synthesis of natural myriaporones.

F. Reyes, C. Cuevas, C. del Pozo, 2004, Angewandte Chemie.

Optically active 1,3,4,4-tetrasubstituted β-lactams: synthesis and evaluation as tumor cell growth inhibitors.

M. García-López, R. González-Muñiz, C. Cuevas, 2011, European journal of medicinal chemistry.

Preparation of penta-azole containing cyclopeptides: challenges in macrocyclization

F. Albericio, C. Cuevas, M. Álvarez, 2007 .

Njaoamines A–F, new cytotoxic polycyclic alkaloids from the haplosclerid sponge Reniera sp.

F. Reyes, C. Cuevas, R. Fernández, 2007 .

Halogenated helianane derivatives from the sponge Spirastrella hartmani.

F. Reyes, C. Cuevas, R. Fernández, 2005, Journal of natural products.

The first total synthesis of the cyclodepsipeptide pipecolidepsin A

Judit Tulla-Puche, F. Albericio, C. Cuevas, 2013, Nature Communications.

Aplicyanins A–F, new cytotoxic bromoindole derivatives from the marine tunicate Aplidium cyaneum

F. Reyes, S. Taboada, C. Cuevas, 2008 .

Identification of three single nucleotide polymorphisms in the chicken insulin-like growth factor 1 and 2 genes and their associations with growth and feeding traits.

A. Sánchez, J. Estany, M. Tor, 2003, Poultry science.

Synthesis and antimitotic and tubulin interaction profiles of novel pinacol derivatives of podophyllotoxins.

I. Barasoain, C. Trigili, J. Andreu, 2012, Journal of medicinal chemistry.

Metabolic Disposition of Lurbinectedin, a Potent Selective Inhibitor of Active Transcription of Protein-Coding Genes, in Nonclinical Species and Patients

J. Schellens, H. Rosing, J. Beijnen, 2022, Drug Metabolism and Disposition.

The effects of grape seed in the diet of the Penedes chicken, on growth and on the chemical composition and sensory profile of meat

A. Francesch, M. Cartañá, 2015, British poultry science.

Meat characteristics of chickens from an F1 cross of two improved Spanish breeds depending on slaughter age

A. Francesch, M. Tor, J. A. Miguel, 2011 .

Tanjungides A and B: New Antitumoral Bromoindole Derived Compounds from Diazona cf formosa. Isolation and Total Synthesis

F. Reyes, C. Cuevas, S. Munt, 2014, Marine drugs.

Methodology for morphological characterization of chicken and its application to compare Penedesenca and Empordanesa breeds

A. Francesch, I. Villalba, M. Cartañá, 2011 .

Comparison of fatty acid profiles of edible meat, adipose tissues and muscles between cocks and capons

J. Estany, M. Tor, A. Francesch, 2005 .

Genetic parameters for egg number, egg weight, and eggshell color in three Catalan poultry breeds.

J. Estany, L. Alfonso, A. Francesch, 1997, Poultry science.

Dearomatizing anionic cyclization of phosphonamides. A route to phosphonic acid derivatives with antitumor properties.

M. Serrano-Ruiz, C. Cuevas, M. Iglesias, 2008, Organic letters.

Double dearomatization of bis(diphenylphosphinamides) through anionic cyclization. A facile route of accessing multifunctional systems with antitumor properties.

M. Serrano-Ruiz, S. García‐Granda, C. Cuevas, 2007, The Journal of organic chemistry.

502 MI130004, an antibody–drug conjugate including a novel payload of marine origin: Evidences of in vivo activity

C. Galmarini, S. Munt, P. Avilés, 2014 .

In vitro studies on the metabolism of trabectedin (YONDELIS) in monkey and man, including human CYP reaction phenotyping.

G. Mannens, F. Cuyckens, P. Avilés, 2009, Biochemical pharmacology.

Highly functionalized β-lactams and 2-ketopiperazines as TRPM8 antagonists with antiallodynic activity

G. Fernández-Ballester, M. Bonache, A. Fernández-Carvajal, 2020, Scientific Reports.

Metabolite profiling of the novel anti-cancer agent, plitidepsin, in urine and faeces in cancer patients after administration of 14C-plitidepsin

J. Schellens, H. Rosing, J. Beijnen, 2018, Cancer Chemotherapy and Pharmacology.

Smallest peptoids with antiproliferative activity on human neoplastic cells.

E. Pérez-Payá, F. Albericio, A. Messeguer, 2007, Journal of medicinal chemistry.

Stolonoxides E and F, cytotoxic metabolites from the marine ascidian Stolonica socialis.

F. Reyes, C. Cuevas, R. Fernández, 2010, Journal of natural products.

Synthesis of Retinals Fluorinated at Odd-Numbered Side-Chain Positions and of the Corresponding Fluorobacteriorhodopsins.

R. Álvarez, A. D. de Lera, A. Francesch, 1997, The Journal of organic chemistry.

The Aplidin analogs PM01215 and PM02781 inhibit angiogenesis in vitro and in vivo

M. Hermann, E. Gunsilius, N. Steiner, 2015, BMC Cancer.

Optically active 1,3,4,4-tetrasubstituted β-lactams: synthesis and evaluation as tumor cell growth inhibitors.

M. García-López, R. González-Muñiz, C. Cuevas, 2011, European journal of medicinal chemistry.