N. Pearson

发表

Flexible palladium-catalysed amidation reactions for the synthesis of complex aryl amides

S. Dabbs, D. Davies, R. Markwell, 2010 .

Parallel synthesis techniques in the identification of new chiral dirhodium(II) carboxylates for asymmetric carbenoid insertion reactions

M. Drysdale, D. Coe, C. Moody, 1998 .

SYNTHESIS OF (-)-GLOEOSPORONE

A. Holmes, M. Looney, N. Pearson, 1991 .

Penem inhibitors of bacterial signal peptidase

R. Southgate, A. Kaura, T. C. Smale, 1995 .

β-, γ- and δ-Lactams as conformational constraints in ring-closing metathesis

A. Holmes, R. Markwell, N. Pearson, 1999 .

Novel tricyclics (e.g., GSK945237) as potent inhibitors of bacterial type IIA topoisomerases.

S. Dabbs, D. Davies, E. Minthorn, 2016, Bioorganic & medicinal chemistry letters.

Novel hydroxyl tricyclics (e.g., GSK966587) as potent inhibitors of bacterial type IIA topoisomerases.

S. Dabbs, D. Davies, E. Minthorn, 2013, Bioorganic & medicinal chemistry letters.

Novel cyclohexyl-amides as potent antibacterials targeting bacterial type IIA topoisomerases.

S. Dabbs, D. Davies, Susanne Eyrisch, 2011, Bioorganic & medicinal chemistry letters.

Novel amino-piperidines as potent antibacterials targeting bacterial type IIA topoisomerases.

S. Dabbs, D. Davies, T. Gallagher, 2011, Bioorganic & medicinal chemistry letters.

New methodology for the synthesis of unsaturated 8-, 9- and 10-membered lactams

A. Nadin, P. Evans, A. Holmes, 1996 .

β-, γ-, and δ-Lactams as Conformational Constraints in Ring-Closing Metathesis.

A. Holmes, R. Markwell, N. Pearson, 2010 .

Type IIA topoisomerase inhibition by a new class of antibacterial agents

Kristin K. Brown, M. Hann, A. Fosberry, 2010, Nature.

N–H insertion reactions of rhodium carbenoids. Part 1. Preparation of α-amino acid and α-aminophosphonic acid derivatives

M. Drysdale, D. Haigh, C. Moody, 1996 .

N-H Insertion Reactions of Rhodium Carbenoids. Part 1. Preparation of . alpha.-Amino Acid and α-Aminophosphonic Acid Derivatives.

M. Drysdale, D. Haigh, C. Moody, 2010 .

Preparation of 3-benzoylpenems and penem amides by wittig methodology

R. Southgate, T. C. Smale, N. Pearson, 1995 .

ASYMMETRIC RHODIUM CARBENOID INSERTION INTO THE SI-H BOND

David C. Forbes, D. C. Forbes, M. Drysdale, 1996 .

The design of efficient and selective routes to pyridyl analogues of 2,3-dihydro-1,4-benzodioxin-6-carbaldehyde

S. Dabbs, D. Davies, Christopher W. Barfoot, 2010 .

The carbenoid approach to peptide synthesis.

M. Drysdale, D. Haigh, D. Coe, 2000, Chemistry.

Asymmetric rhodium carbene insertion into the SiH bond: identification of new dirhodium(II) carboxylate catalysts using parallel synthesis techniques

M. Drysdale, D. Haigh, D. Coe, 2003 .

Structural basis of quinolone inhibition of type IIA topoisomerases and target-mediated resistance

A. Fosberry, M. Gwynn, B. Bax, 2010, Nature Structural &Molecular Biology.

The many faces of RNA

C. Prescott, D. Eggleston, N. Pearson, 2000, Acta crystallographica. Section D, Biological crystallography.

Novel Bacterial Topoisomerase Inhibitor Gepotidacin Demonstrates Absence of Fluoroquinolone-Like Arthropathy in Juvenile Rats

S. Janmohamed, E. Dumont, N. Pearson, 2022, Antimicrobial agents and chemotherapy.

The design of efficient and selective routes to a key 1,4-cis-substituted cyclohexylamide intermediate

D. Davies, M. McGuire, R. Markwell, 2010 .

Design and synthesis of conformationally restricted eight-Membered ring diketones as potential serine protease inhibitors.

A. Kaura, D. Eggleston, R. Haltiwanger, 2002, Bioorganic & medicinal chemistry letters.

RNA as a drug target.

C. Prescott, N. Pearson, N D Pearson, 1997, Chemistry & biology.

Seven-Membered Lactams as Constraints for Amide Self-Recognition

J. Goodman, A. Nadin, A. Holmes, 1995 .

Seven‐Membered Lactams as Constraints for Amide Self‐Recognition.

J. Goodman, A. Nadin, A. Holmes, 1996 .