K. Conde-Knape

发表

Potent, selective MCH-1 receptor antagonists.

S. Berthel, S. Mischke, Y. Qian, 2008, Bioorganic & medicinal chemistry letters.

The common insertional polymorphism in the APOC1 promoter is associated with serum apolipoprotein C-I levels in Hispanic children.

S. Shea, D. Rabinowitz, R. Deckelbaum, 2005, Atherosclerosis.

Potent MCH-1 receptor antagonists from cis-1,4-diaminocyclohexane-derived indane analogs.

S. So, Y. Qian, Yonglin Ren, 2013, Bioorganic & medicinal chemistry letters.

Sex and hormonal status influence the effects of psyllium on lipoprotein remodeling and composition.

S. Vega-López, M. Fernández, R. Vidal-Quintanar, 2002, Metabolism: clinical and experimental.

Beneficial effects of weight loss on plasma apolipoproteins in postmenopausal women.

T. Lohman, S. Vega-López, M. Fernández, 2004, The Journal of nutritional biochemistry.

Discovery of 1-arylcarbonyl-6,7-dimethoxyisoquinoline derivatives as glutamine fructose-6-phosphate amidotransferase (GFAT) inhibitors.

S. So, Shaoqing Chen, Nam T Le, 2011, Bioorganic & medicinal chemistry letters.

Design and synthesis of 2-N-substituted indazolone derivatives as non-carboxylic acid glycogen synthase activators.

Qing Xiang, Xiaolei Zhang, Y. Qian, 2013, Bioorganic & medicinal chemistry letters.

N-substituted sultam carboxylic acids as novel glycogen synthase activators

Qing Xiang, Xiaolei Zhang, Y. Qian, 2013 .

Overexpression of apoC-I in apoE-null mice: severe hypertriglyceridemia due to inhibition of hepatic lipase.

A. Bensadoun, N. Shachter, J. Cohn, 2002, Journal of lipid research.

Discovery of orally active carboxylic acid derivatives of 2-phenyl-5-trifluoromethyloxazole-4-carboxamide as potent diacylglycerol acyltransferase-1 inhibitors for the potential treatment of obesity and diabetes.

C. Rondinone, Yingsi Chen, Y. Qian, 2011, Journal of medicinal chemistry.

Heparan sulfate proteoglycans in experimental models of diabetes: a role for perlecan in diabetes complications

K. Conde-Knape, 2001, Diabetes/metabolism research and reviews.

Overexpression of apoC-III produces lesser hypertriglyceridemia in apoB-48-only gene-targeted mice than in apoB-100-only mice Published, JLR Papers in Press, September 1, 2004. DOI 10.1194/jlr.M400185-JLR200

R. Ramakrishnan, N. Shachter, K. Okada, 2004, Journal of Lipid Research.

Systemic bile acid sensing by G protein‐coupled bile acid receptor 1 (GPBAR1) promotes PYY and GLP‐1 release

P. Mattei, S. Raab, H. Dehmlow, 2013, British journal of pharmacology.

Systemic bile acid sensing by G protein-coupled bile acid receptor 1 ( GPBAR 1 ) promotes PYY and GLP-1 release 1 RUNNING TITLE : Mechanism of GPBAR 1-mediated PYY / GLP-1 release

P. Mattei, S. Raab, H. Dehmlow, 2013 .

Fatty acid modulators for the treatment of diabesity

C. Rondinone, R. Taub, S. Erickson, 2007 .

Discovery and optimisation of 1-hydroxyimino-3,3-diphenylpropanes, a new class of orally active GPBAR1 (TGR5) agonists.

Rainer E. Martin, C. Bissantz, P. Mattei, 2013, Bioorganic & medicinal chemistry letters.

A neutralizing antibody against DKK1 does not reduce plaque formation in classical murine models of atherosclerosis: Is the therapeutic potential lost in translation?

M. Nyberg, K. Hultman, U. Hedin, 2020, Atherosclerosis.

BMP7-induced-Pten inhibits Akt and prevents renal fibrosis.

M. Prunotto, F. Martin, C. Godson, 2017, Biochimica et biophysica acta. Molecular basis of disease.

Discovery and optimization of 2-phenyloxazole derivatives as diacylglycerol acyltransferase-1 inhibitors.

Yingsi Chen, Y. Qian, R. Taub, 2011, Bioorganic & medicinal chemistry letters.

Autotaxin Inhibitor Protects from Chronic Allograft Injury in Rat Kidney Allotransplantation

G. Remuzzi, A. Benigni, M. Noris, 2019, Nephron.

Discovery of camphor-derived pyrazolones as 11β-hydroxysteroid dehydrogenase type 1 inhibitors.

S. So, Yonglin Ren, R. Taub, 2014, Bioorganic & medicinal chemistry letters.

Preparation and characterization of albumin conjugates of a truncated peptide YY analogue for half-life extension.

H. Michel, P. Goelzer, Farooq Qureshi, 2013, Bioconjugate chemistry.

PK modulation of haptenylated peptides via non-covalent antibody complexation.

U. Brinkmann, I. Thorey, K. Stubenrauch, 2013, Journal of controlled release : official journal of the Controlled Release Society.

Discovery of 2-[3,5-dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yloxy)phenyl]-3,5-dioxo-2,3,4,5-tetrahydro[1,2,4]triazine-6-carbonitrile (MGL-3196), a Highly Selective Thyroid Hormone Receptor β agonist in clinical trials for the treatment of dyslipidemia.

S. So, I. Klein, Y. Qian, 2014, Journal of medicinal chemistry.

Discovery of pyrazolo[3,4-d]pyrimidine derivatives as GPR119 agonists.

S. So, M. Myers, G. Saha, 2014, Bioorganic & medicinal chemistry letters.

Unimolecular Dual Incretins Maximize Metabolic Benefits in Rodents, Monkeys, and Humans

Bin Yang, Brian Finan, Tao Ma, 2013, Science Translational Medicine.

Fatty acids increase presenilin-1 levels and γ-secretase activity in PSwt-1 cells Published, JLR Papers in Press, September 17, 2004. DOI 10.1194/jlr.M400317-JLR200

D. Beher, M. Shearman, N. Shachter, 2004, Journal of Lipid Research.

A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents

R. Seeley, D. Drucker, P. Pfluger, 2014, Nature Medicine.

Longitudinal assessment of heart function of ZSF1 rats by echocardiography

A. Bénardeau, I. Lartaud, K. Conde-Knape, 2013 .

Spatial Transcriptional Mapping Reveals Site-Specific Pathways Underlying Human Atherosclerotic Plaque Rupture.

M. Orho-Melander, E. Lutgens, I. Gonçalves, 2023, Journal of the American College of Cardiology.

Unimolecular Dual Incretins Maximize Metabolic Benefits in Rodents, Monkeys, and Humans

D. Drucker, P. Pfluger, M. Tschöp, 2013, Science Translational Medicine.

PK modulation of haptenylated peptides via non-covalent antibody complexation.

U. Brinkmann, I. Thorey, K. Stubenrauch, 2013, Journal of Controlled Release.