B. Chenard

发表

Metal silanolates: organic soluble equivalents for O−2

E. Laganis, B. Chenard, 1984 .

Neuroprotective effects of the N-methyl-D-aspartate receptor antagonists ifenprodil and SL-82,0715 on hippocampal cells in culture.

B. Chenard, I. Shalaby, M. Próchniak, 1992, The Journal of pharmacology and experimental therapeutics.

Effect of CP101,606, a novel NR2B subunit antagonist of the N-methyl-D-aspartate receptor, on the volume of ischemic brain damage off cytotoxic brain edema after middle cerebral artery occlusion in the feline brain.

R. Bullock, P. Fatouros, F. Corwin, 1997, Stroke.

Pyrido[2,3-b]pyrazines, discovery of TRPV1 antagonists with reduced potential for the formation of reactive metabolites.

S. Boyce, J. Krause, Xiaozhang Zheng, 2010, Bioorganic & medicinal chemistry letters.

α-Nitroarylation of Ketones and Esters: An Exceptionally Facile Synthesis of Indoles, 2-Indolinones, and Arylacetic Acids.

T. V. RajanBabu, B. Chenard, M. Petti, 1986 .

Electronic structure calculations of 1,3-dipolar cycloadditions using density functional and Hartree–Fock methods

J. Blake, J. Andzelm, B. Chenard, 1994 .

C5a, But Not C3a, Increases VEGF Secretion in ARPE-19 Human Retinal Pigment Epithelial Cells

J. Krause, B. Chenard, R. Meade, 2009, Current eye research.

Glycine reverses 7-Cl kynurenate blockade of glutamate neurotoxicity in cell culture.

B. Chenard, I. Shalaby, M. Próchniak, 1989, European journal of pharmacology.

G-Protein Coupled Receptor Inverse Agonists: Identification, Pharmacological Relevance and Functional Assays

J. Krause, R. Brodbeck, B. Chenard, 2005 .

Transient receptor potential ion channels as targets for the discovery of pain therapeutics.

J. Krause, B. Chenard, D. Cortright, 2005, Current opinion in investigational drugs.

Acidic isostere design: Synthetic strategies and recent progress in understanding electronic properties and metabolic stability

C. Lipinski, B. Chenard, 1990 .

(1S,2S)-1-(4-Hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidino)-1- propanol: A Potent New Neuroprotectant Which Blocks N-Methyl-D- aspartate Responses.

F. Menniti, W. White, M. Collins, 1995 .

Aminopyrazine CB1 receptor inverse agonists.

Mark T. Kershaw, J. Krause, J. Mao, 2008, Bioorganic & medicinal chemistry letters.

Aminoquinazolines as TRPV1 antagonists: modulation of drug-like properties through the exploration of 2-position substitution.

Mark T. Kershaw, J. Chandrasekhar, J. Krause, 2008, Bioorganic & medicinal chemistry letters.

The inverse-electron-demand Diels-Alder reaction of 3-(methylsulfonyl)-1,2,4-triazine and enamines. Isolation of crystalline intermediates and an improved synthesis of 1-(methylsulfonyl)tetrahydroisoquinolines

G. Schulte, B. Chenard, R. T. Ronau, 1988 .

Silylstannanes in organic synthesis. Scope and limitation of palladium-catalyzed reaction with acetylenes

B. Chenard, C. M. V. Zyl, 1986 .

Discovery of novel 6,6-heterocycles as transient receptor potential vanilloid (TRPV1) antagonists.

Mark T. Kershaw, S. Boyce, J. Krause, 2010, Journal of medicinal chemistry.

Quinazolin-4-one alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonists: structure-activity relationship of the C-2 side chain tether.

F. Menniti, J. Blake, W. M. Welch, 2001, Journal of medicinal chemistry.

Atropisomeric quinazolin-4-one derivatives are potent noncompetitive alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonists.

A. Ganong, F. Menniti, P. Seymour, 2001, Bioorganic & medicinal chemistry letters.

Methaqualone derivatives are potent noncompetitive AMPA receptor antagonists.

F. Menniti, K. Shenk, W. M. Welch, 2000, Bioorganic & medicinal chemistry letters.

Annelation reactions of quinone monoketals. Studies directed at an efficient synthesis of anthracyclinones

A. Sercel, B. Chenard, J. S. Swenton, 1984 .

Silyl stannanes: useful reagents for bis-functionalization of .alpha.,.beta.-unsaturated ketones and acetylenes

T. V. RajanBabu, E. Laganis, B. Chenard, 1985 .

Ethoxymethylenemalonates and Malononitriles (EMM reagents) as formic acid equivalents: Synthesis of fused-imidazoles under neutral or mildly acidic con

J. Macor, B. Chenard, B. E. Segelstein, 1993 .

Atropisomeric Quinazolin-4-one Derivatives Are Potent Noncompetitive α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Antagonists.

B. Chenard, 2001 .

Functional characterization of CP-465,022, a selective, noncompetitive AMPA receptor antagonist

A. Ganong, F. Menniti, J. Lerma, 2002, Neuropharmacology.

A novel methoxy-directed ketal hydrolysis and its application to a convergent, regiospecific synthesis of (.+-.)-daunomycinone

B. Chenard, J. S. Swenton, M. G. Dolson, 1981 .

Reactions of cis-silyl tin olefins: (Anti-Denmark) nazarov cyclization of β-silyl divinyl ketones

D. Sanderson, B. Chenard, C. M. V. Zyl, 1986 .

3-Stannyl-1-silyloxycyclohex-1-enes: synthetic equivalents for ketone α, β-dianions

B. Chenard, 1986 .

Synthesis of high-specific activity tritium and optically pure [14C]CP-101,606. Enantioselective crystallization of a radiochemically racemic mixture

S. Miller, K. E. Mccarthy, M. Dumont, 1997 .

Equilibration of the Oxidative Addition Product of Tetrakis(triphenylphosphine)palladium and Electron-Rich Aryl Halides Leads to Product Scrambling in the Stille Reaction

B. Chenard, T. Butler, B. E. Segelstein, 1995 .

An efficient route to benzo[b]thiophenequinones, quinone bisketals, and quinone monoketals via anodic oxidation of methoxylated benzo[b]thiophenes. Studies directed at the synthesis of functionalized benzo[b]thiophene-4,7-quinones

B. Chenard, J. R. McConnell, J. S. Swenton, 1983 .

Organocopper chemistry of quinone bisketals. Application to the synthesis of isoprenoid quinone systems

B. Chenard, J. S. Swenton, P. Raynolds, 1980 .

Synthesis and chemistry of 2-trimethylsilylbenzocyclobutenones

C. Slapak, B. Chenard, D. K. Anderson, 1981 .

Synthesis, structure, and properties of pentathiepins

R. Harlow, B. Chenard, A. L. Johnson, 1985 .

Benzopentathiepins: synthesis via thermolysis of benzothiadiazoles with sulfur

B. Chenard, T. Miller, 1984 .

Molecular Characterization of the Gerbil C5a Receptor and Identification of a Transmembrane Domain V Amino Acid That Is Crucial for Small Molecule Antagonist Interaction*

D. Severance, J. Krause, R. Brodbeck, 2005, Journal of Biological Chemistry.

Synthesis, structures, and conformation dynamics of pyrazolotetrathiepins and related compounds studied by X-ray crystallography, dynamic NMR, and molecular orbital calculations

D. Dixon, R. Harlow, D. Roe, 1987 .

Synthesis, Structures, and Conformation Dynamics of Pyrazolotetrathiepins and Related Compounds Studied by X-Ray Crystallography, Dynamic NMR, and Molecular Orbital Calculations.

D. Dixon, R. Harlow, D. Roe, 1987 .

Antagonists selective for NMDA receptors containing the NR2B subunit.

F. Menniti, B. Chenard, 1999, Current pharmaceutical design.

(1S,2S)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidino)-1-propanol: a potent new neuroprotectant which blocks N-methyl-D-aspartate responses.

M. Collins, M. Dumont, J. Bordner, 1995, Journal of medicinal chemistry.

Treatment with HC-070, a potent inhibitor of TRPC4 and TRPC5, leads to anxiolytic and antidepressant effects in mice

Georg Rast, Bastian Hengerer, T. Strassmaier, 2018, PloS one.

Characterization of the binding site for a novel class of noncompetitive alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonists.

F. Menniti, W. White, W. M. Welch, 2000, Molecular pharmacology.

α-Nitroarylation of Ketones and Esters: An Exceptionally Facile Synthesis of Indoles, 2-Indolinones, and Arylacetic Acids.

T. V. RajanBabu, B. Chenard, M. Petti, 1986 .

Is Not Neuroprotective In Vivo CP-465 , 022 , a Selective Noncompetitive AMPA Receptor Antagonist , Blocks AMPA

A. Ganong, F. Menniti, P. Seymour, 2002 .

An efficient preparation of beta-aryl-beta-ketophosphonates by the TFAA/H3PO4-mediated acylation of arenes with phosphonoacetic acids.

B. Chenard, C. Seekamp, G. P. Luke, 2008, The Journal of organic chemistry.

Pyrazolothiadiazoles from 3-aminopyrazoles: the hetero-Herz reaction

B. Chenard, 1984 .

CP-101,606: An NR2B-Selective NMDA Receptor Antagonist.

Stephen A. Williams, F. Menniti, K. Wilner, 1998, CNS drug reviews.

CP-101,606, an NR2B subunit selective NMDA receptor antagonist, inhibits NMDA and injury induced c-fos expression and cortical spreading depression in rodents

F. Menniti, W. White, P. Butler, 2000, Neuropharmacology.

A unified approach to systematic isosteric substitution for acidic groups and application to NMDA antagonists related to 2-amino-7-phosphonoheptanoate.

C. Lipinski, B. Dominy, B. Chenard, 1990, Journal of medicinal chemistry.

Separation of alpha 1 adrenergic and N-methyl-D-aspartate antagonist activity in a series of ifenprodil compounds.

Anne W. Schmidt, B. Koe, C. Fox, 1991, Journal of medicinal chemistry.

CP-101,606, a potent neuroprotectant selective for forebrain neurons.

F. Menniti, B. Chenard, I. Shalaby, 1997, European journal of pharmacology.

(3R,4S)-3-[4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl]chroman-4,7-diol: a conformationally restricted analogue of the NR2B subtype-selective NMDA antagonist (1S,2S)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidino)- 1-propanol.

F. Menniti, J. Blake, W. White, 1998, Journal of medicinal chemistry.

A short synthesis of GYKI 52466

F. Menniti, B. Chenard, M. Próchniak, 1993 .

Oxindole N-Methyl-D-Aspartate (NMDA) antagonists

B. Koe, C. Fox, B. Chenard, 1993 .

Use of 2,5-Dimethylpyrrole as an Amino-Protecting Group in an Efficient Synthesis of 5-Amino-3-[(N-methyl- pyrrolidin-2(R)-yl)methyl]indole

J. Macor, B. Chenard, R. Post, 1994 .

Characterization of the binding site for a novel class of noncompetitive alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonists.

F. Menniti, B. Chenard, J. Lazzaro, 2000, Molecular pharmacology.