M. David-Cordonnier

发表

Covalent binding to glutathione of the DNA-alkylating antitumor agent, S23906-1.

C. Bailly, C. Tardy, M. Kouach, 2003, European journal of biochemistry.

c-Myb protein binds to the EP element of the HBV enhancer and regulates transcription in synergy with NF-M.

J. D'halluin, M. Hamdane, M. David-Cordonnier, 1999, Biochimica et biophysica acta.

Direct and Indirect Targeting of HOXA9 Transcription Factor in Acute Myeloid Leukemia

I. Seuningen, M. David-Cordonnier, M. Lambert, 2019, Cancers.

Heterocyclic Diamidine DNA Ligands as HOXA9 Transcription Factor Inhibitors: Design, Molecular Evaluation, and Cellular Consequences in a HOXA9-Dependant Leukemia Cell Model.

Daniel P. Sweat, P. Peixoto, W. Wilson, 2019, Journal of medicinal chemistry.

DNA-Destabilizing Agents as an Alternative Approach for Targeting DNA: Mechanisms of Action and Cellular Consequences

M. David-Cordonnier, G. Lenglet, 2010, Journal of nucleic acids.

Protein Recognition in Drug-Induced DNA Alkylation: When the Moonlight Protein GAPDH Meets S23906-1/DNA Minor Groove Adducts

M. David-Cordonnier, S. Depauw, Gaëlle Savreux-Lenglet, 2015, International journal of molecular sciences.

A transesterification reaction is implicated in the covalent binding of benzo[b]acronycine anticancer agents with DNA and glutathion.

C. Bailly, H. Vezin, M. Kouach, 2004, Bioorganic & medicinal chemistry.

Protein recognition of the S23906-1-DNA adduct by nuclear proteins: direct involvement of glyceraldehyde-3-phosphate dehydrogenase (GAPDH).

M. David-Cordonnier, G. Lenglet, S. Depauw, 2013, The Biochemical journal.

DNA Helix Destabilization by Alkylating Agents: From Covalent Bonding to DNA Repair

M. David-Cordonnier, G. Lenglet, S. Depauw, 2011 .

New Insights on the Mechanism of Quinoline-based DNA Methyltransferase Inhibitors*

A. Mai, L. Mourey, M. Bouhlel, 2014, The Journal of Biological Chemistry.

Rebeccamycin Derivatives as Dual DNA-Damaging Agents and Potent Checkpoint Kinase 1 Inhibitors

L. Meijer, P. Peixoto, B. Pfeiffer, 2008, Molecular Pharmacology.

Biological activity and DNA binding studies of 2-substituted benzimidazo[1,2-a]quinolines bearing different amino side chains

M. Hranjec, M. Kralj, G. Karminski-Zamola,, 2013 .

DNA and non-DNA targets in the mechanism of action of the antitumor drug trabectedin.

O. Olmea, C. Bailly, F. Mollinedo, 2005, Chemistry & biology.

Antiproliferative potency of 2-amino, 5-amino and 2,5-diamino substituted benzimidazo[1,2-a]quinolines: 3D QSAR study and DNA binding properties

M. Hranjec, M. Kralj, G. Karminski-Zamola,, 2016 .

Amino substituted benzimidazo[1,2-a]quinolines: Antiproliferative potency, 3D QSAR study and DNA binding properties.

M. Hranjec, M. Kralj, G. Karminski-Zamola,, 2016, European journal of medicinal chemistry.

Anilides and quinolones with nitrogen-bearing substituents from benzothiophene and thienothiophene series: synthesis, photochemical synthesis, cytostatic evaluation, 3D-derived QSAR analysis and DNA-binding properties.

S. Tomić, M. Kralj, G. Karminski-Zamola,, 2014, European journal of medicinal chemistry.

Water-mediated binding of agents that target the DNA minor groove.

S. Neidle, W. Wilson, Arvind Kumar, 2011, Journal of the American Chemical Society.

Synthesis, antitumor activity, and mechanism of action of benzo[b]chromeno[6,5-g][1,8]naphthyridin-7-one analogs of acronycine.

B. Pfeiffer, Wen Tian, L. Kraus-Berthier, 2014, Journal of medicinal chemistry.

Covalent binding of antitumor benzoacronycines to double-stranded DNA induces helix opening and the formation of single-stranded DNA: unique consequences of a novel DNA-bonding mechanism.

E. De Pauw, C. Bailly, P. Colson, 2005, Molecular cancer therapeutics.

Alkylation of Guanine in DNA by S23906-1, a Novel Potent Antitumor Compound Derived from the Plant Alkaloid Acronycine†

C. Bailly, J. Hickman, M. Kouach, 2002 .

Design of DNA minor groove binding diamidines that recognize GC base pair sequences: a dimeric-hinge interaction motif.

P. Peixoto, C. Bailly, W. Wilson, 2007, Journal of the American Chemical Society.

Influence of the Stereoisomeric Position of the Reactive Acetate Groups of the Benzo[b]Acronycine derivative S23906-1 on Its DNA Alkylation, Helix-Opening, Cytotoxic, and Antitumor Activities

C. Bailly, B. Pfeiffer, F. Tillequin, 2009, Molecular Pharmacology.

DNA minor groove induced dimerization of heterocyclic cations: compound structure, binding affinity, and specificity for a TTAA site.

W. Wilson, Arvind Kumar, D. Boykin, 2010, Journal of molecular biology.

Synthesis and biological activities of 7-aza rebeccamycin analogues bearing the sugar moiety on the nitrogen of the pyridine ring.

P. Peixoto, B. Pfeiffer, M. Prudhomme, 2006, Bioorganic & medicinal chemistry.

In vitro anticancer activity, toxicity and structure-activity relationships of phyllostictine A, a natural oxazatricycloalkenone produced by the fungus Phyllosticta cirsii.

R. Kiss, V. Mathieu, A. Evidente, 2011, Toxicology and applied pharmacology.

Novel phenyl and pyridyl substituted derivatives of isoindolines: Synthesis, antitumor activity and DNA binding features.

G. Karminski-Zamola,, S. Kraljević Pavelić, Nataša Ilić, 2014, European journal of medicinal chemistry.

Photochemical electrocyclisation of 3-vinylindoles to pyrido[2,3-a]-, pyrido[4,3-a]- and thieno[2,3-a]-carbazoles: design, synthesis, DNA binding and antitumor cell cytotoxicity.

M. David-Cordonnier, G. Lenglet, S. Depauw, 2009, European journal of medicinal chemistry.

Novel diamidino-substituted derivatives of phenyl benzothiazolyl and dibenzothiazolyl furans and thiophenes: synthesis, antiproliferative and DNA binding properties.

P. Peixoto, K. Pavelić, G. Karminski-Zamola,, 2010, Journal of medicinal chemistry.

Synthesis, antitumor activity and DNA binding features of benzothiazolyl and benzimidazolyl substituted isoindolines.

G. Karminski-Zamola,, S. Kraljević Pavelić, Nataša Ilić, 2018, Bioorganic & medicinal chemistry.

Novel substituted benzothiophene and thienothiophene carboxanilides and quinolones: synthesis, photochemical synthesis, DNA-binding properties, antitumor evaluation and 3D-derived QSAR analysis.

Maja Aleksić, Sanja Tomić, Raja Nhili, 2012, Journal of medicinal chemistry.

Design, synthesis and biological evaluation of new oligopyrrole carboxamides linked with tricyclic DNA-intercalators as potential DNA ligands or topoisomerase inhibitors.

B. Baldeyrou, A. Lansiaux, M. David-Cordonnier, 2007, European journal of medicinal chemistry.

Antibacterial and antiproliferative activity of novel 2-benzimidazolyl- and 2-benzothiazolyl-substituted benzo[b]thieno-2-carboxamides

D. Verbanac, M. Hranjec, M. Kralj, 2018, Molecular Diversity.

Stereoselectivity, Sequence Specificity and Mechanism of Action of the Azinomycin Epoxide

C. Bailly, M. Kouach, G. Briand, 2006, Chembiochem : a European journal of chemical biology.

Synthesis and biological evaluation of dialkylaminoalkylamino benzo[c][1,7] and [1,8]phenanthrolines as antiproliferative agents.

Soizic Prado, F. Tillequin, F. Porée, 2010, European journal of medicinal chemistry.

Amino- and glycoconjugates of pyrido[4,3,2-kl]acridine. Synthesis, antitumor activity, and DNA binding.

L. Bouffier, O. Renaudet, P. Dumy, 2006, Bioorganic & medicinal chemistry.

Novel amidino substituted benzimidazole and benzothiazole benzo[b]thieno-2-carboxamides exert strong antiproliferative and DNA binding properties.

M. Hranjec, G. Karminski-Zamola,, S. Kraljević Pavelić, 2017, European journal of medicinal chemistry.

Synthesis, cytotoxic activity, and DNA binding properties of antitumor cis-1,2-dihydroxy-1,2-dihydrobenzo[b]acronycine cinnamoyl esters.

B. Pfeiffer, F. Tillequin, T. Gaslonde, 2009, Bioorganic & medicinal chemistry.

Synthesis, cytotoxic activity, and mechanism of action of furo[2,3-c]acridin-6-one and benzo[b]furo[3,2-h]acridin-6-one analogues of psorospermin and acronycine.

B. Pfeiffer, Marie-Christine Lallemand, F. Tillequin, 2008, Journal of medicinal chemistry.

Generation of replication-dependent double-strand breaks by the novel N2-G-alkylator S23906-1.

C. Tardy, R. Golsteyn, V. Poindessous, 2006, Cancer research.

Design, synthesis, and cytotoxic activity of Michael acceptors and enol esters in the benzo[b]acronycine series.

C. Bailly, B. Pfeiffer, F. Tillequin, 2005, Chemical & pharmaceutical bulletin.

Structure-activity relationships and mechanism of action of antitumor benzo[b]pyrano[3,2-h]acridin-7-one acronycine analogues.

C. Bailly, P. Renard, B. Pfeiffer, 2003, Journal of medicinal chemistry.

Further insight into the DNA recognition mechanism of trabectedin from the differential affinity of its demethylated analogue ecteinascidin ET729 for the triplet DNA binding site CGA.

C. Bailly, F. Gago, E. Marco, 2006, Journal of medicinal chemistry.

Design of novel antitumor DNA alkylating agents: the benzacronycine series.

C. Bailly, F. Tillequin, T. Gaslonde, 2004, Current medicinal chemistry. Anti-cancer agents.

The Unusual Monomer Recognition of Guanine-Containing Mixed Sequence DNA by a Dithiophene Heterocyclic Diamidine

P. Peixoto, W. Wilson, Arvind Kumar, 2014, Biochemistry.

Targeting Transcription Factors for Cancer Treatment

Sabine Depauw, Mélanie Lambert, Samy Jambon, 2018, Molecules.

Camptothecins for drug design, cancer cell death and gene targeting

C. Bailly, P. Arimondo, J. Kluza, 2008 .

Direct inhibition of the DNA-binding activity of POU transcription factors Pit-1 and Brn-3 by selective binding of a phenyl-furan-benzimidazole dication

P. Peixoto, C. Bailly, W. Wilson, 2008, Nucleic acids research.

Synthesis and biological activity of novel 2, 5-diamino substituted benzimidazo[1, 2-a]quinolines

M. Hranjec, M. Kralj, G. Karminski-Zamola,, 2014 .

Topoisomerase I-mediated DNA relaxation as a tool to study intercalation of small molecules into supercoiled DNA.

P. Peixoto, C. Bailly, M. David-Cordonnier, 2010, Methods in molecular biology.

Structure‐Dependent Binding of Arylimidamides to the DNA Minor Groove

N. Campbell, S. Neidle, W. Wilson, 2014, Chembiochem : a European journal of chemical biology.

The DNA binding domain of the human c-Abl tyrosine kinase preferentially binds to DNA sequences containing an AAC motif and to distorted DNA structures.

C. Bailly, J. D'halluin, M. Hamdane, 1998, Biochemistry.

Activation of p65 NF-κB protein by p210BCR – ABL in a myeloid cell line (P210BCR – ABL activates p65 NF-κB)

J. D'halluin, M. David-Cordonnier, Malika Hamdane, 1997, Oncogene.

Excision of 8-oxoguanine within clustered damage by the yeast OGG1 protein.

P O'Neill, S. Boiteux, P. O'Neill, 2001, Nucleic acids research.

Targeting the DNA-binding activity of the human ERG transcription factor using new heterocyclic dithiophene diamidines

P. Peixoto, Arvind Kumar, D. Boykin, 2012, Nucleic acids research.

Targeting Transcription Factor Binding to DNA by Competing with DNA Binders as an Approach for Controlling Gene Expression.

M. Bouhlel, M. David-Cordonnier, M. Lambert, 2015, Current topics in medicinal chemistry.

Novel Stable Camptothecin Derivatives Replacing the E-Ring Lactone by a Ketone Function Are Potent Inhibitors of Topoisomerase I and Promising Antitumor Drugs

C. Bailly, J. Hickman, G. Lavielle, 2007, Molecular Pharmacology.

Determination of the human c‐Abl consensus DNA binding site

C. Bailly, J. D'halluin, M. Hamdane, 1998, FEBS letters.

Efficiency of incision of an AP site within clustered DNA damage by the major human AP endonuclease.

Peter O'Neill, Ian D Hickson, I. Hickson, 2002, Biochemistry.

Clustered DNA Damage, Influence on Damage Excision by XRS5 Nuclear Extracts and Escherichia coli Nth and Fpg Proteins*

P O'Neill, P. O'Neill, J. Laval, 2000, The Journal of Biological Chemistry.

Rational Design of Bisubstrate-Type Analogues as Inhibitors of DNA Methyltransferases in Cancer Cells.

M. Bouhlel, P. Arimondo, L. Halby, 2017, Journal of medicinal chemistry.

Synthesis, antiproliferative activity and DNA binding properties of novel 5-aminobenzimidazo[1,2-a]quinoline-6-carbonitriles.

M. Hranjec, M. Kralj, G. Karminski-Zamola,, 2014, European journal of medicinal chemistry.

Antitumor activity, X-ray crystal structure, and DNA binding properties of thiocoraline A, a natural bisintercalating thiodepsipeptide.

C. Bailly, J. Vaquero, F. Gago, 2007, Journal of medicinal chemistry.

Mixed up minor groove binders: Convincing A·T specific compounds to recognize a G·C base pair.

Rupesh K. Nanjunda, W. Wilson, Arvind Kumar, 2015, Bioorganic & medicinal chemistry letters.

Synthesis and biological evaluation of N-substituted benzo[c]phenanthrolines and benzo[c]phenanthrolinones as antiproliferative agents.

Soizic Prado, F. Tillequin, F. Porée, 2011, European journal of medicinal chemistry.

Structure-activity relationships and mechanism of action of antitumor bis 8-hydroxyquinoline substituted benzylamines.

R. Kiss, J. Kraus, T. Cresteil, 2010, European journal of medicinal chemistry.

Design, synthesis, and DNA-binding of N-alkyl(anilino)quinazoline derivatives.

P. Depreux, A. Lemoine, J. Goossens, 2010, Journal of medicinal chemistry.

The DNA-binding domain of human c-Abl tyrosine kinase promotes the interaction of a HMG chromosomal protein with DNA.

M. Waring, C. Bailly, A. Travers, 1999, Nucleic acids research.

Antibacterial and antiproliferative activity of novel 2-benzimidazolyl- and 2-benzothiazolyl-substituted benzo[b]thieno-2-carboxamides

D. Verbanac, M. Hranjec, M. Kralj, 2018, Molecular Diversity.

Synthesis, antitumor activity, and mechanism of action of benzo[a]pyrano[3,2-h]acridin-7-one analogues of acronycine.

B. Pfeiffer, Marie-Christine Lallemand, F. Tillequin, 2006, Journal of Medicinal Chemistry.

Efficiency of excision of 8-oxo-guanine within DNA clustered damage by XRS5 nuclear extracts and purified human OGG1 protein.

P O'Neill, S. Boiteux, P. O'Neill, 2001, Biochemistry.

New anticancer active and selective phenylene-bisbenzothiazoles: synthesis, antiproliferative evaluation and DNA binding.

K. Pavelić, G. Karminski-Zamola,, S. K. Pavelić, 2013, European journal of medicinal chemistry.

Recognition and kinetics for excision of a base lesion within clustered DNA damage by the Escherichia coli proteins Fpg and Nth.

P O'Neill, P. O'Neill, J. Laval, 2001, Biochemistry.

Activation of p65 NF-kappaB protein by p210BCR-ABL in a myeloid cell line (P210BCR-ABL activates p65 NF-kappaB).

J. D'halluin, M. Hamdane, M. David-Cordonnier, 1997, Oncogene.

Design of DNA minor groove binding diamidines that recognize GC base pair sequences: a dimeric-hinge interaction motif.

P. Peixoto, C. Bailly, D. Boykin, 2007, Journal of the American Chemical Society.

Rational Design of Bisubstrate-Type Analogues as Inhibitors of DNA Methyltransferases in Cancer Cells.

M. Bouhlel, P. Arimondo, L. Halby, 2017, Journal of medicinal chemistry.

Structure‐Dependent Binding of Arylimidamides to the DNA Minor Groove

N. Campbell, S. Neidle, W. Wilson, 2014, Chembiochem : a European journal of chemical biology.

Induction of AML cell differentiation using HOXA9/DNA binding inhibitors as a potential therapeutic option for HOXA9‐dependent AML

C. Preudhomme, M. Bouhlel, M. Figeac, 2024, HemaSphere.