Bailing Xu

发表

Three-component one-pot synthesis of 1,2,3,4-tetrahydroquinoline derivatives in hexafluoroisopropanol

Jie-Xing Zhou, Bailing Xu, 2008 .

Discovery of N-arylsulfonyl-indole-2-carboxamide Derivatives as Potent, Selective, and Orally Bioavailable Fructose-1,6-Bisphosphatase Inhibitors- Design, Synthesis, In Vivo Glucose Lowering Effects, and X-ray Crystal Complex Analysis.

Shuainan Liu, Quan Liu, Z. Shen, 2020, Journal of medicinal chemistry.

Synthesis and biological evaluation of pyrimidine derivatives as novel human Pin1 inhibitors.

Xiaoguang Chen, Jing Jin, R. Cao, 2018, Bioorganic & medicinal chemistry.

Synthesis and biological evaluation of novel human Pin1 inhibitors with benzophenone skeleton.

Jie Zhou, Xiaoguang Chen, Chang Liu, 2012, Bioorganic & medicinal chemistry.

Synthesis and biological evaluation of novel quinazoline-derived human Pin1 inhibitors.

Yan-shen Guo, Xiaoguang Chen, Chang Liu, 2011, Bioorganic & medicinal chemistry.

Synthesis and antiproliferative evaluation of novel benzoimidazole-contained oxazole-bridged analogs of combretastatin A-4.

Xiaoguang Chen, Jing Jin, Jie-Xing Zhou, 2013, European journal of medicinal chemistry.

Synthesis and antitumor activity of novel 2-(1-substituted-piperidin-4-ylamino)quinazolines as antitumor agents.

Xin Gao, Xiao-guang Chen, Jing Jin, 2012, Yao xue xue bao = Acta pharmaceutica Sinica.

Design, synthesis and biological evaluation of novel thiazole-based derivatives as human Pin1 inhibitors.

Bailing Xu, Xiaoyu Wang, Guonan Cui, 2020, Bioorganic & medicinal chemistry.

Discovery of 1-substituted benzyl-quinazoline-2,4(1H,3H)-dione derivatives as novel poly(ADP-ribose)polymerase-1 inhibitors.

Xiaoguang Chen, R. Cao, Jie-Xing Zhou, 2015, Bioorganic & medicinal chemistry.

A novel intramolecular DielsAlder cyclization involving indoloazepines

Tiansheng Wang, Bailing Xu, Zhonglin Wei, 2005 .

Discovery of novel quinazoline-2,4(1H,3H)-dione derivatives as potent PARP-2 selective inhibitors.

Fang-fang Lai, Xiaoguang Chen, Jie-Xing Zhou, 2017, Bioorganic & medicinal chemistry.

Discovery of novel indole derivatives as allosteric inhibitors of fructose-1,6-bisphosphatase.

Shuainan Liu, Z. Shen, Bailing Xu, 2015, European journal of medicinal chemistry.

Facile and efficient synthesis of 2-substituted-N1-carbethoxy-2,3-dihydro-4(1H)-quinazolinones in fluorous solvent

Bailing Xu, Jin Ping Chen, R. Qiao, 2008 .

A facile synthesis of 2-substituted-2,3-dihydro-4(1H)-quinazolinones in 2,2,2-trifluoroethanol

Y. Wang, Bailing Xu, R. Qiao, 2007 .

Discovery of 2-substituted 1H-benzo[d]immidazole-4-carboxamide derivatives as novel poly(ADP-ribose)polymerase-1 inhibitors with in vivo anti-tumor activity.

Xiaoguang Chen, R. Cao, Jie-Xing Zhou, 2017, European journal of medicinal chemistry.

A Novel PARP Inhibitor YHP-836 For the Treatment of BRCA-Deficiency Cancers

Jie Zhou, T. Du, Xiaoguang Chen, 2022, Frontiers in Pharmacology.

Discovery of Quinazoline-2,4(1H,3H)-dione Derivatives Containing 3-Substituted Piperizines as Potent PARP-1/2 Inhibitors─Design, Synthesis, In Vivo Antitumor Activity, and X-ray Crystal Structure Analysis.

Xiaoguang Chen, Yan Li, L. Sheng, 2021, Journal of medicinal chemistry.

A three-component one-pot synthesis of 2-alkoxy-4-amino-N-arylthiazole-5-carboxamides

Jie-Xing Zhou, Bailing Xu, Hong-rui Song, 2014 .

[Recent advances in the study of pin1 and its inhibitors].

Chong-Jing Zhang, Bailing Xu, Zhihui Zhang, 2008, Yao xue xue bao = Acta pharmaceutica Sinica.

Stereospecific gating of functional motions in Pin1

Jeffrey W. Peng, Bailing Xu, F. Etzkorn, 2011, Proceedings of the National Academy of Sciences.

Serine-cis-proline and serine-trans-proline isosteres: stereoselective synthesis of (Z)- and (E)-alkene mimics by Still-Wittig and Ireland-Claisen rearrangements.

John R. Goodell, S. Hart, Bailing Xu, 2003, The Journal of organic chemistry.

Synthesis and biological evaluation of N4-(hetero)arylsulfonylquinoxalinones as HIV-1 reverse transcriptase inhibitors.

Ying Guo, Yan Sun, Bailing Xu, 2009, Bioorganic & medicinal chemistry.

Discovery of quinazoline-2,4(1H,3H)-dione derivatives as novel PARP-1/2 inhibitors: design, synthesis and their antitumor activity.

Xiaoguang Chen, R. Cao, Jie-Xing Zhou, 2018, Organic & biomolecular chemistry.

Design, synthesis and biological evaluation of 7-nitro-1H-indole-2-carboxylic acid derivatives as allosteric inhibitors of fructose-1,6-bisphosphatase.

Shuainan Liu, Z. Shen, Jie-Xing Zhou, 2014, Bioorganic & medicinal chemistry.

Synthesis and Pin1 inhibitory activity of thiazole derivatives.

Xiaoguang Chen, Jing Jin, Bailing Xu, 2016, Bioorganic & medicinal chemistry.

A novel derivative of quinazoline, WYK431 induces G2/M phase arrest and apoptosis in human gastric cancer BGC823 cells through the PI3K/Akt pathway.

Xiao-guang Chen, Jing Jin, Bailing Xu, 2014, International journal of oncology.

A Facile Synthesis of 2-Substituted-2,3-dihydro-4(1H)-quinazolinones in 2,2,2-Trifluoroethanol.

Y. Wang, Bailing Xu, R. Qiao, 2008 .

Synthesis and biological evaluation of novel quinoxalinone-based HIV-1 reverse transcriptase inhibitors

Haibo Zhou, Ying Guo, Jie-Xing Zhou, 2014 .

[Mechanism and action characteristics studies of a quinoxalinone compound against HIV-1 replication].

Ying Guo, Bailing Xu, Mingyu Ba, 2013, Yao xue xue bao = Acta pharmaceutica Sinica.

Facile and efficient synthesis of 5, 7-disubstituted thiazolo [5,4-d] pyrimidine-4, 6 (5H, 7H)-diones

Liang Chen, Jie-Xing Zhou, Bailing Xu, 2012 .

Conformationally locked isostere of phosphoSer-cis-Pro inhibits Pin1 23-fold better than phosphoSer-trans-Pro isostere.

Bailing Xu, F. Etzkorn, Ashley B Mullins, 2004, Journal of the American Chemical Society.

Design, synthesis and biological evaluation of indole-2-carboxylic acid derivatives as IDO1/TDO dual inhibitors.

Xiaoguang Chen, Bailing Xu, Xiaoyu Wang, 2019, European journal of medicinal chemistry.

Poly (ADP-ribose) polymerases inhibitor, Zj6413, as a potential therapeutic agent against breast cancer.

Qin Zhou, Xiaoguang Chen, Nina Xue, 2016, Biochemical pharmacology.

Discovery of 3, 6-disubstituted isobenzofuran-1(3H)-ones as novel inhibitors of monoamine oxidases.

Jie Zhou, Tong Xu, Kaiyue Liu, 2022, Bioorganic & medicinal chemistry letters.

Toward flexibility-activity relationships by NMR spectroscopy: dynamics of Pin1 ligands.

Jeffrey W. Peng, B. Wilson, Bailing Xu, 2010, Journal of the American Chemical Society.

XLN306 induces apoptosis in human breast carcinoma MX-1 cells

Y. Li, Xiaoguang Chen, Jing Jin, 2011 .

The use of one-bead one-compound combinatorial library method to identify peptide ligands for α4β1 integrin receptor in non-Hodgkin's lymphoma

K. Lam, M. Renil, Bailing Xu, 2001, Letters in Peptide Science.

[Design, synthesis and biological evaluation of novel 3-(2-oxo-2-substituted acetamido)benzamides as PARP-1 inhibitors].

Xiao-guang Chen, R. Cao, Bailing Xu, 2015, Yao xue xue bao = Acta pharmaceutica Sinica.

Synthesis and cytotoxic evaluation of N-(4-methoxy-1H-benzo[d]imidazol-7-yl)-arylsulfonamide and N-aryl-(4-methoxy-1H-benzo[d]imidazol)-7-sulfonamide analogs of combretastatin A-4

Xiao-guang Chen, Jin-hua Dong, Jie-Xing Zhou, 2011, Journal of Asian natural products research.

Combining the rapid MTT formazan exocytosis assay and the MC65 protection assay led to the discovery of carbazole analogs as small molecule inhibitors of Aβ oligomer-induced cytotoxicity

K. Lam, R. Diaz-Avalos, R. Cheng, 2007, Brain Research.

Quantitative determination of Cpd118, A novel FBPase inhibitor, in dog plasma by HPLC-MS/MS.

Shuainan Liu, Z. Shen, Fenghe Wang, 2021, Bioanalysis.

Discovery of Novel Indole Derivatives as Fructose-1,6-bisphosphatase Inhibitors and X-ray Cocrystal Structures Analysis.

Shuainan Liu, Linxiang Zhao, Bailing Xu, 2021, ACS medicinal chemistry letters.

Discovery of Quinazoline-2,4(1H,3H)-dione Derivatives Containing a Piperizinone Moiety as Potent PARP-1/2 Inhibitors─Design, Synthesis, In Vivo Antitumor Activity, and X-ray Crystal Structure Analysis.

Bailing Xu, M. Ji, Xiaoyu Wang, 2023, Journal of medicinal chemistry.

A novel derivative of quinazoline, WYK431 induces G2/M phase arrest and apoptosis in human gastric cancer BGC823 cells through the PI3K/Akt pathway.

Xiao-guang Chen, Jing Jin, Bailing Xu, 2014, International journal of oncology.