K. Wiggall

发表

Reversible inhibitors of the gastric (H+/K+)-ATPase. 1. 1-Aryl-4-methylpyrrolo[3,2-c]quinolines as conformationally restrained analogues of 4-(arylamino)quinolines.

M. Parsons, C. Leach, R. Ife, 1990, Journal of medicinal chemistry.

Discovery and Preclinical Characterization of GSK1278863 (Daprodustat), a Small Molecule Hypoxia Inducible Factor–Prolyl Hydroxylase Inhibitor for Anemia

M. Pappalardi, K. Duffy, L. Luo, 2017, The Journal of Pharmacology and Experimental Therapeutics.

New IDH1 mutant inhibitors for treatment of acute myeloid leukemia.

Nicholas D. Adams, G. Drewes, M. Bantscheff, 2015, Nature chemical biology.

Synthesis and biological activity of heteroaryl 3-(1,1-dioxo-2H-(1,2,4)-benzothiadizin-3-yl)-4-hydroxy-2(1H)-quinolinone derivatives as hepatitis C virus NS5B polymerase inhibitors.

Adam T. Gates, R. Sarisky, D. Dhanak, 2009, Bioorganic & medicinal chemistry letters.

Reversible inhibitors of the gastric (H+/K+)-ATPase. 2. 1-Arylpyrrolo[3,2-c]quinolines: effect of the 4-substituent.

M. Parsons, C. Leach, R. Ife, 1992, Journal of medicinal chemistry.

Substituted benzothiadizine inhibitors of Hepatitis C virus polymerase.

Dashyant Dhanak, Adam T. Gates, R. Sarisky, 2009, Bioorganic & medicinal chemistry letters.

3-(1,1-dioxo-2H-(1,2,4)-benzothiadiazin-3-yl)-4-hydroxy-2(1H)-quinolinones, potent inhibitors of hepatitis C virus RNA-dependent RNA polymerase.

Dashyant Dhanak, Adam T. Gates, G. Hofmann, 2006, Journal of medicinal chemistry.

Hydrazinonaphthalene and azonaphthalene thrombopoietin mimics are nonpeptidyl promoters of megakaryocytopoiesis.

J. Luengo, R. Shah, K. Duffy, 2001, Journal of medicinal chemistry.

Identification of a pharmacophore for thrombopoietic activity of small, non-peptidyl molecules. 2. Rational design of naphtho[1,2-d]imidazole thrombopoietin mimics.

J. Luengo, S. Miller, L. Zhang, 2002, Journal of medicinal chemistry.

A versatile synthesis of functionalised 2-aminoquinolines by mercury controlled cyclisation of 2-vinylphenylthioureas

K. Wiggall, S. Richardson, 1995 .

Identification of a pharmacophore for thrombopoietic activity of small, non-peptidyl molecules. 1. Discovery and optimization of salicylaldehyde thiosemicarbazone thrombopoietin mimics.

J. Luengo, S. Miller, L. Zhang, 2002, Journal of medicinal chemistry.

Reversible inhibitors of the gastric (H+/K+)-ATPase. 3. 3-substituted-4-(phenylamino)quinolines.

M. Parsons, C. Leach, R. Ife, 1992, Journal of medicinal chemistry.

Discovery of SB-497115, a Small-Molecule Thrombopoietin (TPO) Receptor Agonist for the Treatment of Thrombocytopenia.

Stephen G. Miller, Kevin J. Duffy, J. Luengo, 2004 .

Reversible inhibitors of the gastric (H+/K+)-ATPase. 4. Identification of an inhibitor with an intermediate duration of action.

M. Parsons, C. Leach, R. Ife, 1995, Journal of Medicinal Chemistry.

Discovery and Preclinical Characterization of GSK1278863 (Daprodustat), a Small Molecule Hypoxia Inducible Factor–Prolyl Hydroxylase Inhibitor for Anemia

M. Pappalardi, K. Duffy, L. Luo, 2017, The Journal of Pharmacology and Experimental Therapeutics.