J. Shotwell

发表

Efficient stereoselective syntheses of isopanepoxydone and panepoxydone: a re-assignment of relative configuration

C. Crews, J. L. Wood, J. Shotwell, 2000 .

Discovery of selective small molecule type III phosphatidylinositol 4-kinase alpha (PI4KIIIα) inhibitors as anti hepatitis C (HCV) agents.

C. Moore, A. Mathis, J. Botyánszki, 2014, Journal of medicinal chemistry.

Discovery of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidines: potent inhibitors of the IGF-1R receptor tyrosine kinase.

L. Shewchuk, P. Sabbatini, A. Hassell, 2009, Bioorganic & medicinal chemistry letters.

Optimization of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine IGF-1R tyrosine kinase inhibitors towards JNK selectivity.

L. Shewchuk, P. Sabbatini, A. Hassell, 2009, Bioorganic & medicinal chemistry letters.

Discovery of a potent boronic acid derived inhibitor of the HCV RNA-dependent RNA polymerase.

R. Hamatake, Z. Hong, Shawn P. Williams, 2014, Journal of medicinal chemistry.

Small-molecule inhibitors of the cell cycle: an overview.

C. Crews, J. Shotwell, 2003, Progress in cell cycle research.

Structure and Energetics of the Samarium Diiodide-HMPA Complex in Tetrahydrofuran.

J. Shotwell, Jennifer M. Sealy, R. A. Flowers, 1999, The Journal of organic chemistry.

Inhibitors of NF-kappaB signaling: design and synthesis of a biotinylated isopanepoxydone affinity reagent.

C. Crews, J. L. Wood, J. Shotwell, 2002, Bioorganic & medicinal chemistry letters.

In Vitro Characterization of GSK2485852, a Novel Hepatitis C Virus Polymerase Inhibitor

R. Hamatake, Z. Hong, J. Vamathevan, 2013, Antimicrobial Agents and Chemotherapy.

Imidazo[1,2-a]pyridines That Directly Interact with Hepatitis C NS4B: Initial Preclinical Characterization.

D. J. Price, M. Thomson, R. Crosby, 2012, ACS medicinal chemistry letters.

Design of N-Benzoxaborole Benzofuran GSK8175—Optimization of Human Pharmacokinetics Inspired by Metabolites of a Failed Clinical HCV Inhibitor

D. J. Price, John Miller, Shawn P. Williams, 2019, Journal of medicinal chemistry.

Hepatitis C replication inhibitors that target the viral NS4B protein.

D. J. Price, R. Hamatake, Z. Hong, 2014, Journal of medicinal chemistry.

Calorimetric determination of the solution affinity of YbCl3 for HMPA in tetrahydrofuran

J. Shotwell, R. A. Flowers, 1998 .

Reversible carboxamide-mediated internal activation at C(6) of 2-chloro-4-anilino-1H-pyrrolo[2,3-d]pyrimidines.

K. Stevens, Joseph W. Wilson, S. Patnaik, 2008, The Journal of organic chemistry.

Efficient syntheses of novel C2'-alkylated (+/-)-K252a analogues.

T. Nheu, D. Petsch, Y. Hirokawa, 2001, Organic letters.

Efficient protiodesilylation of unactivated C(sp3)-SiMe2Ph bonds using tetrabutylammonium fluoride.

W. Roush, E. Mertz, J. Shotwell, 2005, Organic letters.

Synthesis of the C11-C29 fragment of amphidinolide F.

W. Roush, J. Shotwell, 2004, Organic letters.

Efficient protiodesilylation of unactivated C(sp3)-SiMe2Ph bonds using tetrabutylammonium fluoride.

W. Roush, E. Mertz, J. Shotwell, 2005, Organic letters.

Efficient construction of the securine A carbon skeleton.

J. Shotwell, S. Chaffee, P. Korakas, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Stereoselective syntheses of the C(1)-C(9) fragment of amphidinolide C.

Robert H Bates, W. Roush, J. Shotwell, 2008, Organic letters.

Abstract PR02: Integrated metabolic and epigenomic reprograming by H3K27M mutations in diffuse intrinsic pontine gliomas

A. Chinnaiyan, Ho-Joon Lee, S. Blüml, 2020, Oral Presentations - Proffered Abstracts.

GSK1838705A inhibits the insulin-like growth factor-1 receptor and anaplastic lymphoma kinase and shows antitumor activity in experimental models of human cancers

P. Sabbatini, R. Kruger, Rakesh Kumar, 2009, Molecular Cancer Therapeutics.

The Role of Phosphodiesterase 12 (PDE12) as a Negative Regulator of the Innate Immune Response and the Discovery of Antiviral Inhibitors*

Cecil E. Rise, B. Wisely, T. Sheahan, 2015, The Journal of Biological Chemistry.

The HPK1 Inhibitor A-745 Verifies the Potential of Modulating T Cell Kinase Signaling for Immunotherapy.

Ryan A McClure, K. Longenecker, Chaohong Sun, 2022, ACS chemical biology.

Novel Modes of Inhibition of Wild-Type Isocitrate Dehydrogenase 1 (IDH1): Direct Covalent Modification of His315.

A. Vasudevan, Chaohong Sun, C. Jakob, 2018, Journal of medicinal chemistry.

Total synthesis of luminacin D.

C. Crews, J. Hines, J. Shotwell, 2002, Organic letters.

Small Molecule IL-36 gamma Antagonist as a Novel Therapeutic Approach for Plaque Psoriasis.

P. Richardson, Chaohong Sun, R. Henry, 2019 .

Small Molecule IL-36γ Antagonist as a Novel Therapeutic Approach for Plaque Psoriasis

P. Richardson, Chaohong Sun, R. Henry, 2019, Scientific Reports.

Discovery of 3,5-disubstituted-1H-pyrrolo[2,3-b]pyridines as potent inhibitors of the insulin-like growth factor-1 receptor (IGF-1R) tyrosine kinase.

Samarjit Patnaik, Felix Deanda, Hiroko Nakamura, 2009, Bioorganic & medicinal chemistry letters.

Electrochemical Investigation of the Solvolytic Properties of Ethylammonium Nitrate (EAN) and Propylammonium Nitrate (PAN)

J. Shotwell, R. A. Flowers, 2000 .

GSK1838705A inhibits the insulin-like growth factor-1 receptor and anaplastic lymphoma kinase and shows antitumor activity in experimental models of human cancers

P. Sabbatini, R. Kruger, S. Rabindran, 2009, Molecular Cancer Therapeutics.