V. Borodkin

发表

Substrate dependent intramolecular Pauson-Khand reaction of carbohydrate exo-methylene derivatives. Unexpected formation of fused “[4.1.0] bicycloheptene - pyranose” tricyclic product

V. Azov, N. K. Kochetkov, V. Borodkin, 1996 .

Catalytic deficiency of O-GlcNAc transferase leads to X-linked intellectual disability

D. V. van Aalten, M. Gundogdu, S. Joss, 2019, Proceedings of the National Academy of Sciences.

Chemical Dissection of the Link between Streptozotocin, O-glcnac, and Pancreatic Cell Death

D. V. van Aalten, V. Borodkin, Shalini Pathak, 2022 .

The conserved threonine-rich region of the HCF-1PRO repeat activates promiscuous OGT:UDP-GlcNAc glycosylation and proteolysis activities

W. Herr, D. V. van Aalten, V. Zoete, 2018, The Journal of Biological Chemistry.

Proteolysis of HCF-1 by Ser/Thr glycosylation-incompetent O-GlcNAc transferase:UDP-GlcNAc complexes

W. Herr, D. V. van Aalten, V. Zoete, 2016, Genes & development.

The chemical synthesis of bioactive glycosylphosphatidylinositols from Trypanosoma cruzi containing an unsaturated fatty acid in the lipid.

M. Ferguson, V. Borodkin, A. Nikolaev, 2006, Angewandte Chemie.

An efficient and versatile synthesis of GlcNAcstatins—potent and selective O-GlcNAcase inhibitors built on the tetrahydroimidazo[1,2-a]pyridine scaffold

D. V. van Aalten, V. Borodkin, 2010, Tetrahedron.

Total synthesis of erythronolide B. 2. Skeleton assembly in (C5C9) + (C3C4) + (C1C2) + (C11C13) sequence.

N. K. Kochetkov, V. Borodkin, D. Yashunsky, 1987 .

Synthesis of oligomeric phosphono analogues of Leishmania lipophosphoglycan fragments

M. Ferguson, V. Borodkin, A. Nikolaev, 2002 .

Synthesis of β-d-Galp-(1→4)-α-d-Manp methanephosphonate, a substrate analogue for the elongating α-d-mannosyl phosphate transferase in the Leishmania

M. Ferguson, V. Borodkin, A. Nikolaev, 2001 .

The chemical synthesis of bioactive glycosylphosphatidylinositols from Trypanosoma cruzi containing an unsaturated fatty acid in the lipid.

M. Ferguson, V. Borodkin, A. Nikolaev, 2006, Angewandte Chemie.

Stereo-controlled synthesis of erythronolides A and B from 1,6-anhydro-β-D-glucopyranose (levoglucosan). Skeleton assembly in (C9 – C13) + (C7 – C8) + (C1 – C6) sequence

N. K. Kochetkov, V. Borodkin, D. Yashunsky, 1989 .

Synthesis of macrolide antibiotics. 18. Stereospecific building up of the carbon chain of erythronolide B

V. Borodkin, M. Ermolenko, A. Sviridov, 1989 .

Synthesis of macrolide antibiotics. 14. Synthesis of 1-methylene-3,5-O-isopropylidene-9,11-O-p-(methoxybenzylidene)-9(S)-dihydro derivative of seco acid of 9(S)-dihydroerythronolide B

N. K. Kochetkov, V. Borodkin, M. Ermolenko, 1989 .

Synthesis of macrolide antibiotics. Communication 8. Synthesis of acyclic forms of C9-C13 fragment of erythronolide B

N. K. Kochetkov, V. Borodkin, M. Ermolenko, 1985 .

Synthesis of potential bisubstrate inhibitors of Leishmania elongating α-D-mannosyl phosphate transferase

M. Ferguson, V. Borodkin, A. Nikolaev, 2004 .

Synthesis of macrolide antibiotics

N. K. Kochetkov, V. Borodkin, M. Ermolenko, 1989 .

Synthesis of macrolide antibiotics. 19. Synthesis of the C7-C13 fragment of erythronolide A

N. K. Kochetkov, V. Borodkin, A. Sviridov, 1990 .

Probing elongating and branching β-D-galactosyltransferase activities in Leishmania parasites by making use of synthetic phosphoglycans.

M. Ferguson, O. Sizova, I. Ivanova, 2011, ACS chemical biology.

Structural insights into mechanism and specificity of O-GlcNAc transferase

A. W. Schüttelkopf, D. V. van Aalten, V. Borodkin, 2008, The EMBO journal.

Structural insights into mechanism and specificity of O-GlcNAc transferase This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits distribution,andreproductioninanymedium,providedtheoriginalauthorandsourcearecredited.Thislicensedoesnot pe

V. Borodkin, S. Shepherd, Shalini Pathak, 2008 .

Synthesis of C-methyldesoxy sugars: Desoxygenation of tertiary alcohol xanthogenates and hydrozirconation of exomethylene derivatives of carbohydrates

N. K. Kochetkov, V. Borodkin, M. Ermolenko, 1986 .

Total synthesis of erythronolide B. 1. Skeleton assembly in (C9C13) + (C7C8) + (C1C6) sequence.

N. K. Kochetkov, V. Borodkin, D. Yashunsky, 1987 .

Stereocontrolled synthesis of erythronolides A and B in a (C5-C9) + (C3-C4) + (C1-C2) + (C11-C13) sequence from 1.6-anhydro-β-D-glycopyranose (levoglucosan). Part 1. Synthesis of C1-C10 and C11-C13 segments

N. K. Kochetkov, V. Borodkin, D. Yashunsky, 1991 .

Synthesis of macrolide antibiotics. 16. Synthesis of erythronolides A and B by a coupling scheme of (C5-C9) + (C3-C4) + (C1-C2) + (C10) + (C11-C13) fragments and synthesis of the C5-C9 fragment

V. Borodkin, M. Ermolenko, A. Sviridov, 1989 .

Synthesis of macrolide antibiotics. 13. synthesis of certain derivatives of the seco-acid of erythronolide B

N. K. Kochetkov, V. Borodkin, M. Ermolenko, 1989 .

Synthesis of macrocyclic antibiotics. 9. Synthesis of the C9−C13 fragments of 12-epineomethinolide and methinolide

N. K. Kochetkov, V. Borodkin, M. Ermolenko, 1986 .

Substrate and product analogues as human O-GlcNAc transferase inhibitors

D. V. van Aalten, I. Navratilova, V. Borodkin, 2010, Amino Acids.

Stereocontrolled synthesis of erythronolides A and B in A (C5-C9) + (C3-C4) + (C1-C2) + (C11-C13) sequence from 1,6-anhydro-β-D-glucopyranose (levoglucosan). Part 2.

N. K. Kochetkov, V. Borodkin, D. Yashunsky, 1991 .

GlcNAcstatin: a picomolar, selective O-GlcNAcase inhibitor that modulates intracellular O-glcNAcylation levels.

D. V. van Aalten, N. Shpiro, V. Borodkin, 2006, Journal of the American Chemical Society.

GlcNAcstatins are nanomolar inhibitors of human O-GlcNAcase inducing cellular hyper-O-GlcNAcylation

D. V. van Aalten, V. Borodkin, M. Schimpl, 2009, The Biochemical journal.

Bisubstrate UDP–peptide conjugates as human O-GlcNAc transferase inhibitors

D. Robinson, M. Gundogdu, V. Borodkin, 2013, The Biochemical journal.

Synthesis of macrocyclic antibiotics. 10. Synthesis of the C9−C13 fragment of neomethinolide

N. K. Kochetkov, V. Borodkin, M. Ermolenko, 1986 .

Catalytic deficiency of O-GlcNAc transferase leads to X-linked intellectual disability

D. V. van Aalten, M. Gundogdu, S. Joss, 2019, Proceedings of the National Academy of Sciences.

Proteome Wide Purification and Identification of O‑glcnac-modified Proteins Using Click Chemistry and Mass Spectrometry

B. Kuster, Hannes Hahne, D. Helm, 2022 .

The active site of O-GlcNAc transferase imposes constraints on substrate sequence

A. W. Schüttelkopf, D. V. van Aalten, J. Alonso, 2015, Nature Structural &Molecular Biology.

Thio-Linked UDP–Peptide Conjugates as O-GlcNAc Transferase Inhibitors

D. V. van Aalten, V. Borodkin, K. Rafie, 2018, Bioconjugate chemistry.

Genetic recoding to dissect the roles of site-specific protein O-GlcNAcylation

D. V. van Aalten, S. G. Bartual, V. Borodkin, 2019, Nature Structural & Molecular Biology.

O-GlcNAc transferase invokes nucleotide sugar pyrophosphate participation in catalysis

A. W. Schüttelkopf, D. V. van Aalten, D. Robinson, 2012, Nature chemical biology.

O-GlcNAcylation of TAB1 modulates TAK1-mediated cytokine release

D. V. van Aalten, D. Campbell, V. Borodkin, 2010, The EMBO journal.

A Trapped Covalent Intermediate of a Glycoside Hydrolase on the Pathway to Transglycosylation. Insights from Experiments and Quantum Mechanics/Molecular Mechanics Simulations.

D. V. van Aalten, C. Rovira, J. Castro-López, 2016, Journal of the American Chemical Society.

A mechanism-inspired UDP-N-acetylglucosamine pyrophosphorylase inhibitor

Michael D. Urbaniak, M. Ferguson, D. V. van Aalten, 2020, RSC chemical biology.

A mutant O-GlcNAcase as a probe to reveal global dynamics of protein O-GlcNAcylation during Drosophila embryonic development.

I. Navratilova, J. Alonso, V. Borodkin, 2015, The Biochemical journal.

Synergy of Peptide and Sugar in O-GlcNAcase Substrate Recognition

D. V. van Aalten, V. Borodkin, M. Schimpl, 2012, Chemistry & biology.

Human OGA binds substrates in a conserved peptide recognition groove

A. W. Schüttelkopf, D. V. van Aalten, V. Borodkin, 2010, The Biochemical journal.

Recognition of a glycosylation substrate by the O-GlcNAc transferase TPR repeats

D. V. van Aalten, V. Borodkin, O. Raimi, 2017, Open Biology.

O-GlcNAcase Fragment Discovery with Fluorescence Polarimetry.

D. V. van Aalten, I. Navratilova, V. Borodkin, 2018, ACS chemical biology.

Cell-Penetrant, Nanomolar O-GlcNAcase Inhibitors Selective against Lysosomal Hexosaminidases

K. Read, D. V. van Aalten, V. Borodkin, 2010, Chemistry & biology.

A Structural and Biochemical Model of Processive Chitin Synthesis

D. V. van Aalten, V. Borodkin, A. Ferenbach, 2014, The Journal of Biological Chemistry.

O-GlcNAcylation of TAB1 modulates TAK1-mediated cytokine release

D. V. van Aalten, D. Campbell, V. Borodkin, 2012, The EMBO Journal.

O-GlcNAcylation of TAB1 modulates TAK1-mediated cytokine release

D. V. van Aalten, D. Campbell, V. Borodkin, 2012, The EMBO journal.

Proteome wide purification and identification of O-GlcNAc-modified proteins using click chemistry and mass spectrometry.

Hannes Hahne, D. V. van Aalten, V. Borodkin, 2013, Journal of proteome research.

Human OGA binds substrates in a conserved peptide recognition groove

A. W. Schüttelkopf, D. V. van Aalten, V. Borodkin, 2010, The Biochemical journal.

Chemical Dissection of the Link between Streptozotocin, O-GlcNAc, and Pancreatic Cell Death

D. V. van Aalten, V. Borodkin, Shalini Pathak, 2008, Chemistry & biology.