C. Kohchi

发表

Delivery of rifampicin-PLGA microspheres into alveolar macrophages is promising for treatment of tuberculosis.

G. Soma, H. Inagawa, H. Terada, 2010, Journal of controlled release : official journal of the Controlled Release Society.

Unique molecular characteristics of the environmental responses of mucosal macrophages.

G. Soma, H. Inagawa, T. Nishizawa, 2006, Anticancer research.

Selective delivery of rifampicin incorporated into poly(DL-lactic-co-glycolic) acid microspheres after phagocytotic uptake by alveolar macrophages, and the killing effect against intracellular Mycobacterium bovis Calmette-Guérin.

G. Soma, H. Inagawa, H. Terada, 2006, Microbes and infection.

The role of toll-like receptor 2 in survival strategies of Mycobacterium tuberculosis in macrophage phagosomes.

G. Soma, H. Inagawa, T. Nishizawa, 2009, Anticancer research.

Intestinal macrophages involved in the homeostasis of the intestine have the potential for responding to LPS.

G. Soma, H. Inagawa, T. Nishizawa, 2009, Anticancer research.

Utilization of macrophages in anticancer therapy: the macrophage network theory.

G. Soma, H. Inagawa, H. Terada, 2004, Anticancer research.

Chemical constituents of malagasy liverworts, part V: prenyl bibenzyls and clerodane diterpenoids with nitric oxide inhibitory activity from Radula appressa and Thysananthus spathulistipus.

G. Soma, Y. Asakawa, T. Nishizawa, 2006, Chemical & pharmaceutical bulletin.

Lipopolysaccharide-activated alveolar macrophages having cytotoxicity toward lung tumor cells through cell-to-cell binding-dependent mechanism.

G. Soma, H. Taniguchi, H. Inagawa, 2010, Anticancer research.

Protective effects of the immunopotentiator from Pantoea agglomerans 1 on chemotherapeutic agent-induced macrophage growth inhibition.

G. Soma, Y. Matsumoto, G. Watanabe, 2010, Anticancer research.

Oral administration of immunopotentiator from Pantoea agglomerans 1 (IP-PA1) improves the survival of B16 melanoma-inoculated model mice.

G. Soma, Y. Matsumoto, G. Watanabe, 2011, Experimental animals.

Nucleotide sequence of Candida pelliculosa beta-glucosidase gene.

A. Toh-E, C. Kohchi, A. Toh-e, 1985, Nucleic acids research.

Comparative immunological analysis of innate immunity activation after oral administration of wheat fermented extract to teleost fish.

G. Soma, H. Inagawa, Yukinori Takahashi, 2009, Anticancer research.

Oncorhynchus mykiss Trout Permeability-Increasing Protein in Rainbow Protein and Bactericidal of Mammalian Lipopolysaccharide-Binding Cloning and Characterization of the Homolog Yokomizo

H. Inagawa, Y. Yokomizo, Y. Yoshiura, 2002 .

Cloning and Characterization of the Homolog of Mammalian Lipopolysaccharide-Binding Protein and Bactericidal Permeability-Increasing Protein in Rainbow Trout Oncorhynchus mykiss1

G. Soma, H. Inagawa, Y. Yokomizo, 2002, The Journal of Immunology.

Cytotoxic and Protective Activity of Nitric Oxide in Cancers

G. Soma, H. Inagawa, C. Kohchi, 2010 .

Existence of galanin in lumbosacral sympathetic ganglionic neurons that project to the quail uterine oviduct.

K. Ukena, K. Tsutsui, T. Ubuka, 2000, Endocrinology.

Stimulation of Phagocytic Activity of Alveolar Macrophages Toward Artificial Microspheres by Infection with Mycobacteria

G. Soma, H. Inagawa, H. Terada, 2008, Pharmaceutical Research.

Cloning and characterization of a TNF-like protein of Plecoglossus altivelis (ayu fish).

G. Soma, H. Inagawa, Yukinori Takahashi, 2007, Molecular immunology.

Anti-inflammatory and Insulin Signaling Phenotype Induced by Repeated Lipopolysaccharide Stimulation in 3T3-L1 Adipocytes

G. Soma, H. Inagawa, C. Kohchi, 2022, AntiCancer Research.

Expression and activity of 3β-hydroxysteroid dehydrogenase/Δ5-Δ4-isomerase in different regions of the avian brain

K. Ukena, K. Tsutsui, R. Lea, 1999, Brain Research.

A mixture of Salacia oblonga extract and IP-PA1 reduces fasting plasma glucose (FPG) and low-density lipoprotein (LDL) cholesterol levels

M. Kuroki, G. Soma, H. Yoshimura, 2011, Nutrition research and practice.

Two types of tumor necrosis factor-alpha in bluefin tuna (Thunnus orientalis) genes: Molecular cloning and expression profile in response to several immunological stimulants.

G. Soma, H. Inagawa, Yukinori Takahashi, 2009, Fish & shellfish immunology.

ROS and innate immunity.

G. Soma, H. Inagawa, T. Nishizawa, 2009, Anticancer research.

Reconsideration of macrophage and dendritic cell classification.

G. Soma, M. Hirashima, H. Inagawa, 2012, Anticancer research.

Profile of cytokines produced in tumor tissue after administration of cyclophosphamide in a combination therapy with tumor necrosis factor.

G. Soma, N. Nagasue, H. Inagawa, 2004, Anticancer research.

Oral Administration of Lipopolysaccharide of Acetic Acid Bacteria Protects Pollen Allergy in a Murine Model.

G. Soma, H. Inagawa, S. Amano, 2015, Anticancer research.

Cloning of Candida pelliculosa β-glucosidase gene and its expression in Saccharomyces cerevisiae

A. Toh-E, C. Kohchi, A. Toh-e, 1986, Molecular and General Genetics MGG.

Effect of topical application of lipopolysaccharide on contact hypersensitivity.

H. Inagawa, M. Hara-Chikuma, Manami Tanaka, 2021, Biochemical and biophysical research communications.

Suppression of response to foreign substances by intestinal macrophages.

G. Soma, H. Inagawa, T. Nishizawa, 2007, Anticancer research.

Improvement of allergic dermatitis via regulation of the Th1/Th2 immune system balance by macrophages activated with lipopolysaccharide derived from Pantoea agglomerans (IP-PA1).

G. Soma, H. Inagawa, T. Nishizawa, 2009, Anticancer research.

Specific messenger RNA expression for signal transduction molecules by lipopolysaccharide in intestinal macrophages

G. Soma, H. Inagawa, T. Nishizawa, 2006, Clinical and experimental immunology.

Inherent potential for production of tumor necrosis factor-α by human intestinal macrophages

G. Soma, H. Yoshimura, N. Nagasue, 2006, International Journal of Colorectal Disease.

Mechanism for maintaining homeostasis in the immune system of the intestine.

G. Soma, H. Inagawa, T. Nishizawa, 2009, Anticancer research.

Cytotoxic effects of activated alveolar macrophages on lung carcinoma cells via cell-to-cell contact and nitric oxide.

G. Soma, H. Taniguchi, H. Inagawa, 2010, Anticancer research.

Antitumor effect of inhalatory lipopolysaccharide and synergetic effect in combination with cyclophosphamide.

G. Soma, H. Taniguchi, H. Inagawa, 2010, Anticancer research.

Innate-immune therapy for lung carcinoma based on tissue-macrophage activation with lipopolysaccharide.

G. Soma, H. Inagawa, H. Terada, 2005, Anticancer research.

Immune recovery effects of immunopotentiator from Pantoea agglomerans 1 (IP-PA1) on low antibody productions in response to Salmonella enteritidis vaccine and sheep red blood cells in dexamethasone-treated stressed chicken models.

G. Soma, Y. Matsumoto, G. Watanabe, 2010, The Journal of veterinary medical science.

Usefulness of oral administration of lipopolysaccharide for disease prevention through the induction of priming in macrophages.

G. Soma, H. Inagawa, C. Kohchi, 2014, Anticancer research.

Intracellular localization of CD14 protein in intestinal macrophages.

G. Soma, H. Inagawa, T. Nishizawa, 2009, Anticancer research.

Purification and Properties of β-Glucosidase from Candida pelliculosa var. acetaetherius

S. Nagai, C. Kohchi, M. Hayashi, 1985 .

Lipopolysaccharides Derived from Pantoea agglomerans Can Promote the Phagocytic Activity of Amyloid β in Mouse Microglial Cells.

G. Soma, T. Masaki, H. Inagawa, 2017, Anticancer research.

Grifolin derivatives from Albatrellus caeruleoporus, new inhibitors of nitric oxide production in RAW 264.7 cells.

G. Soma, Y. Asakawa, T. Nishizawa, 2006, Bioorganic & medicinal chemistry.

Bioactive compounds from liverworts: Inhibition of lipopolysaccharide-induced inducible NOS mRNA in RAW 264.7 cells by herbertenoids and cuparenoids.

G. Soma, Y. Asakawa, T. Nishizawa, 2007, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Development of a drug delivery system using a model that mimics chronic infection of Mycobacterium bovis Calmette-Guerin in alveolar macrophages.

G. Soma, H. Inagawa, H. Hori, 2007, Anticancer research.

A Novel Anti-inflammatory Phenotype Transformed by Repetitive Low-dose Lipopolysaccharide in Primary Peritoneal Tissue-resident Macrophages

G. Soma, H. Inagawa, Haruka Mizobuchi, 2020, AntiCancer Research.

Neurosteroid biosynthesis in vertebrate brains.

K. Ukena, K. Tsutsui, R. Lea, 1999, Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology.

Inhibition of nitric oxide production in RAW 264.7 cells by azaphilones from xylariaceous fungi.

G. Soma, Y. Asakawa, T. Nishizawa, 2006, Biological & pharmaceutical bulletin.

Orally administered LPS enhances head kidney macrophage activation with down-regulation of IL-6 in common carp (Cyprinus carpio).

G. Soma, H. Inagawa, Yukinori Takahashi, 2013, Fish & shellfish immunology.

Inhibitory activity of nitric oxide production in RAW 264.7 cells of daldinals A–C from the fungus Daldinia childiae and other metabolites isolated from inedible mushrooms

G. Soma, Y. Asakawa, T. Nishizawa, 2006, Journal of Natural Medicines.

Isolation of a cDNA Encoding for a Carboxypeptidase, having Leucine Zipper Structure at the N-terminal Region, from the Cultured Shoot Primordia of Matricaria chamomilla

M. Yasuda, T. Hirata, C. Kohchi, 1999 .

Subchronic (90‐day) toxicity assessment of Somacy‐FP100, a lipopolysaccharide‐containing fermented wheat flour extract from Pantoea agglomerans

R. Simon, C. Kohchi, Y. Nakata, 2020, Journal of applied toxicology : JAT.

Cloning and characterization of a LPS-regulatory gene having an LPS binding domain in kuruma prawn Marsupenaeus japonicus.

G. Soma, H. Inagawa, Yukinori Takahashi, 2006, Molecular immunology.

Applications of lipopolysaccharide derived from Pantoea agglomerans (IP-PA1) for health care based on macrophage network theory.

S. Nagai, G. Soma, H. Inagawa, 2006, Journal of bioscience and bioengineering.

Functional characterization of lipopolysaccharide derived from symbiotic bacteria in rice as a macrophage-activating substance.

G. Soma, M. Hirashima, H. Inagawa, 2011, Anticancer research.

Age- and region-specific expressions of the messenger RNAs encoding for steroidogenic enzymes P450scc, P450c17 and 3β-HSD in the postnatal rat brain

K. Ukena, K. Tsutsui, C. Kohchi, 1998, Brain Research.

Molecular cloning of a cDNA of a camptothecin-resistant human DNA topoisomerase I and identification of mutation sites

Eric Patterson, Ken Nishikawa, Ryutaro Yamada, 1991, Nucleic Acids Res..

Preparation of lipopolysaccharide derived from Pantoea agglomerans labeled with fluorescence as a tracer for kinetics analysis.

G. Soma, M. Hirashima, H. Inagawa, 2010, Anticancer research.

Prevention of Diabetes-Associated Cognitive Dysfunction Through Oral Administration of Lipopolysaccharide Derived From Pantoea agglomerans

G. Soma, H. Inagawa, Haruka Mizobuchi, 2021, Frontiers in Immunology.

Attempt to Construct an In Vitro Model of Enhancement of Macrophage Phagocytosis Via Continuous Administration of LPS

G. Soma, H. Inagawa, Haruka Mizobuchi, 2020, AntiCancer Research.

A unique hybrid characteristic having both pro- and anti-inflammatory phenotype transformed by repetitive low-dose lipopolysaccharide in C8-B4 microglia

G. Soma, H. Inagawa, Haruka Mizobuchi, 2020, Scientific Reports.

The Effect of Lipopolysaccharide-containing Moisturizing Cream on Skin Care in Patients With Mild Atopic Dermatitis

G. Soma, K. Nakai, Y. Kubota, 2018, In Vivo.

Dewaxed Brown Rice Feed Improves Fatty Liver in Obese and Diabetic Model Mice

G. Soma, H. Inagawa, C. Kohchi, 2018, AntiCancer Research.

Oral administration of Pantoea agglomerans-derived lipopolysaccharide prevents metabolic dysfunction and Alzheimer’s disease-related memory loss in senescence-accelerated prone 8 (SAMP8) mice fed a high-fat diet

G. Soma, H. Inagawa, Yutaro Kobayashi, 2018, PloS one.

Oral administration of Pantoea agglomerans-derived lipopolysaccharide prevents development of atherosclerosis in high-fat diet-fed apoE-deficient mice via ameliorating hyperlipidemia, pro-inflammatory mediators and oxidative responses

G. Soma, H. Inagawa, Yutaro Kobayashi, 2018, PloS one.

Effects of 3 months continuous intake of supplement containing Pantoea agglomerans LPS to maintain normal bloodstream in adults: Parallel double‐blind randomized controlled study

G. Soma, H. Yoshimura, C. Kohchi, 2017, Food science & nutrition.

Immunopotentiator from Pantoea agglomerans 1 (IP-PA1) Promotes Murine Hair Growth and Human Dermal Papilla Cell Gene Expression.

G. Soma, T. Nishizawa, K. Wakame, 2016, Anticancer research.

Recovery from immunosuppression-related disorders in humans and animals by IP-PA1, an edible lipopolysaccharide.

G. Soma, Y. Matsumoto, G. Watanabe, 2010, Anticancer research.

Molecular cloning and expression analysis of a macrophage-colony stimulating factor receptor-like gene from rainbow trout, Oncorhynchus mykiss.

G. Soma, H. Inagawa, Y. Yokomizo, 2005, Molecular immunology.

Utility and safety of LPS-based fermented flour extract as a macrophage activator.

G. Soma, H. Inagawa, T. Nishizawa, 2009, Anticancer research.

Expression and Activity of 3β-Hydroxysteroid Dehydrogenase/Δ5-Δ4-Isomerase in the Rat Purkinje Neuron during Neonatal Life.

K. Ukena, K. Tsutsui, C. Kohchi, 1999, Endocrinology.

Multiple roles of cyclooxygenase-2 in endometrial cancer.

G. Soma, M. Inoue, H. Inagawa, 2005, Anticancer research.

Cytochrome P450 side-chain cleavage enzyme in the cerebellar Purkinje neuron and its neonatal change in rats.

K. Ukena, K. Tsutsui, C. Kohchi, 1998, Endocrinology.

Expression and activity of 3beta-hydroxysteroid dehydrogenase/delta5-delta4-isomerase in the rat Purkinje neuron during neonatal life.

K. Ukena, K. Tsutsui, C. Kohchi, 1999, Endocrinology.

Oral administration of lipopolysaccharides for the prevention of various diseases: benefit and usefulness.

G. Soma, H. Inagawa, C. Kohchi, 2011, Anticancer research.

Induction of nitric oxide production in RAW264.7 cells under serum-free conditions by O-antigen polysaccharide of lipopolysaccharide.

G. Soma, H. Inagawa, C. Kohchi, 2013, Anticancer research.

Development and potential use of a monoclonal antibody to the lipopolysaccharide of Pantoea agglomerans (IP-PA1).

G. Soma, H. Inagawa, T. Nishizawa, 2007, Anticancer research.

Inherent potential for production of tumor necrosis factor-alpha by human intestinal macrophages.

G. Soma, H. Yoshimura, N. Nagasue, 2006, International journal of colorectal disease.

Enhanced Effect of Hyaluronan and Elastin Synthesis in Fibroblasts Through Lipopolysaccharide-activated Macrophages

H. Inagawa, C. Kohchi, T. Honda, 2020, AntiCancer Research.

Dewaxed Brown Rice Contains a Significant Amount of Lipopolysaccharide Pointing to Macrophage Activation via TLRs.

G. Soma, H. Inagawa, C. Kohchi, 2016, Anticancer research.

Primed Activation of Macrophages by Oral Administration of Lipopolysaccharide Derived from Pantoea agglomerans.

G. Soma, H. Inagawa, Yutaro Kobayashi, 2016, In vivo.

Effects of the Subaleurone Layer of Rice on Macrophage Activation and Protection of Pollen Allergy in a Murine Model.

G. Soma, H. Inagawa, Y. Tamura, 2015, Anticancer research.

A soluble 17 kDa tumour necrosis factor (TNF) mutein, TNF-SAM2, with membrane-bound TNF-like biological characteristics.

G. Soma, H. Inagawa, H. Hori, 2006, Anticancer research.

Correlation of histological localization of tumor-associated macrophages with clinicopathological features in endometrial cancer.

G. Soma, M. Inoue, K. Koike, 2004, Anticancer research.

Molecular cloning of a cDNA that encodes the precursor to several exogastrula-inducing peptides, epidermal-growth-factor-related polypeptides of the sea urchin Anthocidaris crassispina.

G. Soma, D. Mizuno, C. Kohchi, 1995, European journal of biochemistry.

Bis(bibenzyls) from liverworts inhibit lipopolysaccharide-induced inducible NOS in RAW 264.7 cells: a study of structure-activity relationships and molecular mechanism.

G. Soma, Y. Asakawa, L. Harinantenaina, 2005, Journal of natural products.

Involvement of 26-kDa membrane-bound tumour necrosis factor precursor in bidirectional feedback regulation on 17-kDa tumour necrosis factor production after stimulation by lipopolysaccharide.

G. Soma, D. Mizuno, C. Kohchi, 1998, Cytokine.

Treatments for the activating macrophages that reduces surgical stress and postoperative mortalities from bacterial infections and tumor metastases.

G. Soma, H. Yoshimura, H. Inagawa, 2007, In vivo.

Avian galanin: cloning of complementary DNAs and characterization of transcripts in different tissues.

K. Tsutsui, C. Kohchi, Chie Kohchi, 2000, The Journal of experimental zoology.

Constitutive expression of TNF-alpha and -beta genes in mouse embryo: roles of cytokines as regulator and effector on development.

G. Soma, D. Mizuno, C. Kohchi, 1994, The International journal of biochemistry.

New Approach of Lipopolysaccharide Derived from Dietary-Experienced Gram-Negative Bacteria (IP-PA1) Based on the Macrophage-Network

G. Soma, H. Inagawa, C. Kohchi, 2007 .

Characterization of 5-HT2A receptor desensitization and the effect of cycloheximide on it in C6 cells

S. Yamawaki, A. Kagaya, I. Miyoshi, 2001, Journal of Neural Transmission.

A unique hybrid characteristic having both pro- and anti-inflammatory phenotype transformed by repetitive low-dose lipopolysaccharide in C8-B4 microglia

G. Soma, H. Inagawa, Haruka Mizobuchi, 2020, Scientific Reports.

Oral Administration of Lipopolysaccharide Prevents Cognitive Impairment in Streptozotocin-induced Diabetic Mice in a Blood Glucose-independent Manner

G. Soma, H. Inagawa, Haruka Mizobuchi, 2021, AntiCancer Research.

Effect of Lipopolysaccharide Derived from Pantoea agglomerans on the Phagocytic Activity of Amyloid β by Primary Murine Microglial Cells.

G. Soma, H. Inagawa, Yutaro Kobayashi, 2016, Anticancer research.

Improvement Effect of Dewaxed Brown Rice on Constipation in Antibiotic-treated Mice.

G. Soma, H. Inagawa, C. Kohchi, 2017, In vivo.

Chemical Constituents of Malagasy Liverworts. Part 5. Prenyl Bibenzyls and Clerodane Diterpenoids with Nitric Oxide Inhibitory Activity from Radula appressa and Thysananthus spathulistipus.

G. Soma, Y. Asakawa, T. Nishizawa, 2006 .

Innate Immunity Activated by Oral Administration of LPSp Is Phylogenetically Preserved and Developed in Broiler Chickens.

G. Soma, H. Inagawa, Keiko Saito, 2015, Anticancer research.

Anti-lipopolysaccharide factor evokes indirect killing of virulent bacteria in kuruma prawn.

G. Soma, H. Inagawa, T. Nishizawa, 2011, In vivo.

Expression of tumor necrosis factor-alpha and -beta transcripts in embryonal carcinoma and trophoblast cell lines: inflammation-like state as possible regulatory mechanism for ontogenesis.

G. Soma, D. Mizuno, C. Kohchi, 1991, European cytokine network.

Expression of transcripts of complement components and their receptors during differentiation of embryonal carcinoma cell lines.

G. Soma, H. Oshima, D. Mizuno, 1992, Biochemical and biophysical research communications.

Preventative and Therapeutic Potential of Lipopolysaccharide Derived from Edible Gram-Negative Bacteria to Various Diseases

G. Soma, H. Inagawa, T. Nishizawa, 2008 .

Establishment of an in vitro model using NR8383 cells and Mycobacterium bovis Calmette-Guerin that mimics a chronic infection of Mycobacterium tuberculosis.

G. Soma, H. Inagawa, H. Terada, 2005, In vivo.

Expression and Activity of 3 b -Hydroxysteroid Dehydrogenase/ D 5 - D 4 -Isomerase in the Rat Purkinje Neuron during Neonatal Life*

K. Ukena, K. Tsutsui, C. Kohchi, 1999 .

Highly Efficient Absorbents for Removing 32P-Labeled Nucleotides from Experimental Waste.

C. Kohchi, Miyoko Nakano, Kazuo Iwatani, 1997 .

Expression and Activity of 3 b -Hydroxysteroid Dehydrogenase/ D 5 - D 4 -Isomerase in the Rat Purkinje Neuron during Neonatal Life*

K. Ukena, K. Tsutsui, C. Kohchi, 1999 .

Selective lysis of early embryonic cells by the alternative pathway of complement--a possible mechanism for programmed cell death in embryogenesis.

G. Soma, H. Oshima, R. Kircheis, 1996, In vivo.

Foods Containing Pantoea agglomerans LPS Reduce Eye-Nose Allergies—A Double-Blind, Placebo-Controlled, Randomized, Parallel-Group Comparative Pilot Study

G. Soma, H. Inagawa, C. Kohchi, 2023, International Journal of Translational Medicine.