M. Kranz

发表

Identification of PDE4B Over 4D subtype-selective inhibitors revealing an unprecedented binding mode.

Brian Evans, Michael Kranz, J. Gross, 2009, Bioorganic & medicinal chemistry.

Quinolines as a novel structural class of potent and selective PDE4 inhibitors: optimisation for oral administration.

M. Lindvall, D. Somers, T. Shipley, 2009, Bioorganic & medicinal chemistry letters.

The synthesis of cyclic tetrapeptoid analogues of the antiprotozoal natural product apicidin.

S. Croft, M. Ladlow, A. Holmes, 2001, Bioorganic & medicinal chemistry letters.

The discovery of potent and selective kynurenine 3-monooxygenase inhibitors for the treatment of acute pancreatitis.

M. Hann, D. Mole, J. Liddle, 2017, Bioorganic & medicinal chemistry letters.

The discovery of phthalazinone-based human H1 and H3 single-ligand antagonists suitable for intranasal administration for the treatment of allergic rhinitis.

Kenneth L. Clark, Duncan S. Holmes, Michael Kranz, 2011, Journal of medicinal chemistry.

Studies on the Bisoxazoline and (-)-Sparteine Mediated Enantioselective Addition of Organolithium Reagents to Imines.

S. Denmark, N. Nakajima, O. J. Nicaise, 2008, Advanced synthesis & catalysis.

Structural basis of quinolone inhibition of type IIA topoisomerases and target-mediated resistance

A. Fosberry, M. Gwynn, B. Bax, 2010, Nature Structural &Molecular Biology.

Rotational barriers of 1,1'-binaphthyls: a computational study

P. Schleyer, T. Clark, M. Kranz, 1993 .

Organic super-electron-donors: initiators in transition metal-free haloarene–arene coupling

T. Tuttle, B. Mondal, John A. Murphy, 2014 .

An Ab initio Study of the P-C Bond Rotation in Phosphoryl- and Thiophosphoryl-Stabilized Carbanions: Five- and Six-Membered Heterocycles

Scott R. Wilson, S. Denmark, M. Kranz, 1996 .

An ab Initio Study of the P-C Bond Rotation in Phosphorus-Stabilized Carbanions: The Phosphoryl versus Thiophosphoryl Group

S. Denmark, M. Kranz, 1995 .

SYNTHESIS AND STRUCTURE OF THE HETEROBIMETALLIC LADDER COMPLEX (MESNH)SN(MU -NMA)2(LI.2THF)2 (MES = 2,4,6-ME3C6H2, MA = 2-MEOC6H4)

D. Wright, Michael A. Beswick, R. Allan, 1998 .

Azaborines: an ab initio study

T. Clark, M. Kranz, 1992 .

Solution, solid phase and computational structures of apicidin and its backbone‐reduced analogs

R. Upton, W. Clegg, M. Elsegood, 2006, Journal of peptide science : an official publication of the European Peptide Society.

CSAR 2014: A Benchmark Exercise Using Unpublished Data from Pharma

Richard D. Smith, Heather A. Carlson, Aqeel Ahmed, 2016, J. Chem. Inf. Model..

A pharma-wide approach to address the genotoxicity prediction of primary aromatic amines

Mick D. Fellows, Robert A. Jolly, Alexander Amberg, 2018, Computational Toxicology.

Evaluation of aromatic amines with different purities and different solvent vehicles in the Ames test.

Paul L A Popelier, Michael Kranz, James Harvey, 2015, Regulatory toxicology and pharmacology : RTP.

Quinolines as a novel structural class of potent and selective PDE4 inhibitors. Optimisation for inhaled administration.

Tony W Dean, Michael D. Woodrow, D. Somers, 2009, Bioorganic & medicinal chemistry letters.

1,5-Dilithiated arenes: double metal bridging verified by three X-ray structures and MNDO calculations

A. Kos, P. Schleyer, T. Clark, 1993 .