Brian G. Monks

发表

A TIR Domain Variant of MyD88 Adapter-like (Mal)/TIRAP Results in Loss of MyD88 Binding and Reduced TLR2/TLR4 Signaling*

Douglas T. Golenbock, Katherine A. Fitzgerald, Mihai G. Netea, 2009, The Journal of Biological Chemistry.

The AIM2 inflammasome is essential for host-defense against cytosolic bacteria and DNA viruses

Eva Szomolanyi-Tsuda, Shruti Sharma, V. Hornung, 2010, Nature Immunology.

Lipopolysaccharide Rapidly Traffics to and from the Golgi Apparatus with the Toll-like Receptor 4-MD-2-CD14 Complex in a Process That Is Distinct from the Initiation of Signal Transduction* 210

Douglas T. Golenbock, Egil Lien, Terje Espevik, 2002, The Journal of Biological Chemistry.

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

K. Schroder, D. Kastner, I. Vetter, 2015, Nature Medicine.

LPS-TLR4 Signaling to IRF-3/7 and NF-κB Involves the Toll Adapters TRAM and TRIF

Daniel R. Caffrey, B. Monks, D. Golenbock, 2003, The Journal of experimental medicine.

Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide.

B. Monks, D. Golenbock, H. Heine, 2000, The Journal of clinical investigation.

Cutting edge: cells that carry A null allele for toll-like receptor 2 are capable of responding to endotoxin.

B. Monks, D. Golenbock, M. Rothe, 1999, Journal of immunology.

Mouse, but not Human STING, Binds and Signals in Response to the Vascular Disrupting Agent 5,6-Dimethylxanthenone-4-Acetic Acid

B. Monks, T. Xiao, R. Vance, 2013, The Journal of Immunology.

Cutting Edge: NF-κB Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression1

E. Alnemri, V. Hornung, B. Monks, 2009, The Journal of Immunology.

Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9

B. Monks, D. Golenbock, E. Latz, 2007, Proceedings of the National Academy of Sciences.

Efficacy and Pharmacology of the NLRP3 Inflammasome Inhibitor CP-456,773 (CRID3) in Murine Models of Dermal and Pulmonary Inflammation

B. Monks, E. Latz, D. Hepworth, 2016, The Journal of Immunology.

Pulmonary Inflammation ( CRID 3 ) in Murine Models of Dermal and Inflammasome Inhibitor CP-456 , 773 Efficacy and Pharmacology of the NLRP 3

B. Monks, E. Latz, D. Hepworth, 2016 .

The NALP3 inflammasome is involved in the innate immune response to amyloid-β

K. Moore, T. Reinheckel, V. Hornung, 2008, Nature Immunology.

A Long Noncoding RNA Mediates Both Activation and Repression of Immune Response Genes

Daniel R. Caffrey, J. Lawrence, M. Moore, 2013, Science.

The RNA Helicase Lgp2 Inhibits TLR-Independent Sensing of Viral Replication by Retinoic Acid-Inducible Gene-I1

S. Akira, Masahiro Yamamoto, B. Monks, 2005, The Journal of Immunology.

Ligand-induced conformational changes allosterically activate Toll-like receptor 9

B. Monks, D. Golenbock, E. Latz, 2007, Nature Immunology.

The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction.

S. Akira, N. Gay, Masahiro Yamamoto, 2006, Proceedings of the National Academy of Sciences of the United States of America.

TLR9 signals after translocating from the ER to CpG DNA in the lysosome

B. Monks, D. Golenbock, E. Latz, 2004, Nature Immunology.

5,6-Dimethylxanthenone-4-Acetic Acid Disrupting Agent Signals in Response to the Vascular Mouse, but not Human STING, Binds and

B. Monks, R. Vance, S. Vogel, 2013 .

Binding of C4b-Binding Protein to Porin

A. Blom, B. Dahlbäck, S. Ram, 2001, The Journal of experimental medicine.

Binding of C4b-binding protein to porin: a molecular mechanism of serum resistance of Neisseria gonorrhoeae

A. Blom, B. Dahlbäck, S. Ram, 2001 .

Binding of C4b-binding protein: A molecular mechanism of serum resistance of Neisseria gonorrhoeae

A. Blom, B. Dahlbäck, S. Ram, 2001 .

Molecular Characterization of the Interaction between Sialylated Neisseria gonorrhoeae and Factor H*

S. Ram, B. Monks, P. Rice, 2011, The Journal of Biological Chemistry.

Human polymorphism at microRNAs and microRNA target sites.

Charles E. Vejnar, Daniel R. Caffrey, L. Liang, 2013 .

The functional importance of a cap site-proximal region of the human prointerleukin 1 beta gene is defined by viral protein trans-activation

A. C. Webb, G. Hunninghake, B. Monks, 1992, Molecular and cellular biology.

A Fluorescent Reporter Mouse for Inflammasome Assembly Demonstrates an Important Role for Cell-Bound and Free ASC Specks during In Vivo Infection.

B. Monks, D. Golenbock, E. Latz, 2016, Cell reports.

ASC has extracellular and prionoid activities that propagate inflammation

S. Hornemann, A. Aguzzi, B. Monks, 2014, Nature Immunology.

CD11/CD18 and CD14 share a common lipid A signaling pathway.

B. Monks, D. Golenbock, W. Christ, 1998, Journal of immunology.

Binding of C 4 b-binding protein : A molecular mechanism of serum resistance of Neisseria gonorrhoeae

A. Blom, B. Dahlbäck, S. Ram, 2001 .

Human Factor H Interacts Selectively with Neisseria gonorrhoeae and Results in Species-Specific Complement Evasion1

S. Ram, S. Gulati, B. Monks, 2008, The Journal of Immunology.

Species-Specific Complement Evasion Neisseria gonorrhoeae and Results in Human Factor H Interacts Selectively with

S. Ram, S. Gulati, B. Monks, 2013 .

Pharmacological Inhibition of Endotoxin Responses Is Achieved by Targeting the TLR4 Coreceptor, MD-21

B. Monks, D. Golenbock, E. Latz, 2005, The Journal of Immunology.

Targeted Deletion of the Lipopolysaccharide (LPS)-binding Protein Gene Leads to Profound Suppression of LPS Responses Ex Vivo, whereas In Vivo Responses Remain Intact

M. Wurfel, R. Thieringer, B. Monks, 1997, The Journal of experimental medicine.

RNA and β-Hemolysin of Group B Streptococcus Induce Interleukin-1β (IL-1β) by Activating NLRP3 Inflammasomes in Mouse Macrophages*

B. Monks, D. Golenbock, Shruti Sharma, 2014, The Journal of Biological Chemistry.

A Novel Factor H–Fc Chimeric Immunotherapeutic Molecule against Neisseria gonorrhoeae

M. Unemo, M. Ohnishi, S. Ram, 2012, The Journal of Immunology.

Neisseria gonorrhoeae Immunotherapeutic Molecule against Fc Chimeric - A Novel Factor H

M. Unemo, M. Ohnishi, S. Gulati, 2016 .

iGLuc: a luciferase-based inflammasome and protease activity reporter

V. Hornung, B. Monks, E. Latz, 2013, Nature Methods.

Involvement of Toll-like Receptor (TLR) 2 and TLR4 in Cell Activation by Mannuronic Acid Polymers*

S. Akira, O. Takeuchi, B. Monks, 2002, The Journal of Biological Chemistry.