Dirksen Bussiere

Discovery of 3-(2,6-dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), a potent and selective inhibitor of the fibroblast growth factor receptor family of receptor tyrosine kinase.

Pascal Furet, C. Schnell, J. Brueggen, 2011, Journal of medicinal chemistry.

Identification of NVP-BKM120 as a Potent, Selective, Orally Bioavailable Class I PI3 Kinase Inhibitor for Treating Cancer.

Simon Ng, Yanchen Zhang, Kenneth Crawford, 2011, ACS medicinal chemistry letters.