Mioko Hirayama

A novel class of cycloalkano[b]pyridines as potent and orally active opioid receptor-like 1 antagonists with minimal binding affinity to the hERG K+ channel.

Hisashi Ohta, Hiroshi Kawamoto, Satoshi Ozaki, 2008, Journal of medicinal chemistry.

2-Cyclohexylcarbonylbenzimidazoles as potent, orally available and brain-penetrable opioid receptor-like 1 (ORL1) antagonists.

Hisashi Ohta, Hiroshi Kawamoto, Satoshi Ozaki, 2009, Bioorganic & medicinal chemistry letters.