Peter Hodder

发表

Table 1, Assays from the HTS campaign and prior probe discovery effort (ML121)

Timothy P. Spicer, Dmitriy Minond, I Enogieru, 2014 .

Figure 8, Lead profiling screen results summary

Dmitriy Minond, Peter Hodder, Michael D. Cameron, 2013 .

Table 2, Assays for the current probe discovery effort (ML302)

Timothy P. Spicer, Dmitriy Minond, I Enogieru, 2014 .

Monitoring of HTS Compound Library Quality via a High-Resolution Image Acquisition and Processing Instrument

Peter Hodder, Louis Scampavia, Pierre Baillargeon, 2011, Journal of laboratory automation.

Figure 14, Overlay of differential HDX data onto the docking model of 2hfp bound to ML244

Peter Hodder, Bruce M. Spiegelman, Naresh Kumar, 2013 .

Figure 5, Flow chart of HTS screening for NOX1 inhibitors

Peter Hodder, Hui Zhang, William R. Roush, 2011 .

Figure 6, CRC overlay of muscarinic rM1 – rM5 selectivity profile for ML326 (VU0467903)

Peter Hodder, Thomas M. Bridges, Michael R. Wood, 2013 .

Figure 5, One Step Synthesis of ML328

Peter Hodder, Timothy P. Spicer, Michael D. Cameron, 2013 .

Figure 8, Comparison of the structures of the original HTS lead and final Probe ML322

Peter Hodder, Franck Madoux, Peter Chase, 2014 .

Table 1, All PubChem AIDs for the Mcl-1inhibitor project

Dmitriy Minond, Peter Hodder, Michael D. Cameron, 2013 .

Table 11, Ricerca profiling of probe ML322: SID 103771539 /CID49800087

Peter Hodder, Franck Madoux, Peter Chase, 2014 .

Figure 5, CRC overlay for CID 2145491

Peter Hodder, Thomas M. Bridges, Michael R. Wood, 2013 .

Table 5, Pan Labs profiling of ML326 and selected results for ML172

Peter Hodder, Thomas M. Bridges, Michael R. Wood, 2013 .

Figure 6, Cartoon showing the critical path of the High Throughput Screening (HTS) campaign hit selection process and numeric assay cutoffs

Peter Hodder, Naresh Kumar, Michael D. Cameron, 2013 .

Figure 10, One Step Synthesis of ML346 (CID 767276)

Sa Saldanha, Peter Hodder, Franck Madoux, 2013 .

Figure 4, Selection of SID 49716510 as the starting point for SAR hit optimization

Peter Hodder, Franck Madoux, Peter Chase, 2014 .

Table S1, Activity of cherry-picked HTS hits against pPAFAH as assessed by gel-based competitive ABPP (AID 588474)

Peter Hodder, Hugh Rosen, Benjamin F. Cravatt, 2014 .

Table 1, HCV Core Inhibitors Project (see also Summary AID 1911)

Peter Hodder, Franck Madoux, Peter Chase, 2014 .

Ligand-binding pocket shape differences between sphingosine 1-phosphate (S1P) receptors S1P1 and S1P3 determine efficiency of chemical probe identification by ultrahigh-throughput screening.

Peter Hodder, Peter Chase, Hugh Rosen, 2008, ACS chemical biology.

Identification of Small-Molecule Inhibitors of the Colorectal Cancer Oncogene Krüppel-like Factor 5 Expression by Ultrahigh-Throughput Screening

Peter Hodder, Stephan Schürer, Franck Madoux, 2011, Molecular Cancer Therapeutics.

Discovery and SAR of muscarinic receptor subtype 1 (M1) allosteric activators from a molecular libraries high throughput screen. Part 1: 2,5-dibenzyl-2H-pyrazolo[4,3-c]quinolin-3(5H)-ones as positive allosteric modulators.

Peter Hodder, P. Jeffrey Conn, Craig W. Lindsley, 2015, Bioorganic & medicinal chemistry letters.

Hydroxyquinoline-derived compounds and analoguing of selective Mcl-1 inhibitors using a functional biomarker.

Dmitriy Minond, Peter Hodder, Noel Blake, 2013, Bioorganic & medicinal chemistry.

Table 2, Summary of Results

Peter Hodder, Scott Simanski, Franck Madoux, 2013 .

Improved Scalability of Neuron-Based Phenotypic Screening Assays for Therapeutic Discovery in Neuropsychiatric Disorders

Peter Hodder, Christopher Hubbs, Murat Kilinc, 2017, Molecular Neuropsychiatry.

High-Throughput Orthogonal Screening Methionyl-tRNA Synthetase via Trypanosoma brucei Identification of Potent Inhibitors of the

Peter Hodder, Louis Scampavia, Franck Madoux, 2014 .

Application of Parallel Multiparametric Cell-Based FLIPR Detection Assays for the Identification of Modulators of the Muscarinic Acetylcholine Receptor 4 (M4)

Peter Hodder, Louis Scampavia, Franck Madoux, 2015, Journal of biomolecular screening.

Development of an intact cell reporter gene beta-lactamase assay for G protein-coupled receptors for high-throughput screening.

James Inglese, Peter Hodder, Berta Strulovici, 2003, Analytical biochemistry.