J. Nicola

发表

The KCNQ1‐KCNE2 K+ channel is required for adequate thyroid I− uptake

G. Abbott, N. Carrasco, A. Reyna-Neyra, 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Dietary I(-) absorption: expression and regulation of the Na(+)/I(-) symporter in the intestine.

N. Carrasco, J. Nicola, A. M. Masini-Repiso, 2015, Vitamins and hormones.

Mechanism of anion selectivity and stoichiometry of the Na+/I- symporter (NIS)

E. Dadachova, S. Eskandari, N. Carrasco, 2011, Proceedings of the National Academy of Sciences.

Neonatal endotoxin stimulation is associated with a long-term bronchiolar epithelial expression of innate immune and anti-allergic markers that attenuates the allergic response

J. Nicola, L. García, C. Leimgruber, 2020, PloS one.

Neonatal endotoxin stimulation was associated with long- term innate immune markers and an anti-allergic response in bronchiolar epithelium in spite of allergen challenge

J. Nicola, L. García, C. Leimgruber, 2019, bioRxiv.

A Carboxy-Terminal Monoleucine-Based Motif Participates in the Basolateral Targeting of the Na+/I- Symporter.

Carlos P. Modenutti, M. Martí, T. Pourcher, 2018, Endocrinology.

Implications of Na+/I- Symporter Transport to the Plasma Membrane for Thyroid Hormonogenesis and Radioiodide Therapy

J. Nicola, A. M. Masini-Repiso, Mariano Martín, 2018, Journal of the Endocrine Society.

Sodium/Iodide Symporter Mutant V270E Causes Stunted Growth but No Cognitive Deficiency.

L. Amzel, P. Saenger, R. Muzumdar, 2015, The Journal of clinical endocrinology and metabolism.

Functional toll-like receptor 4 conferring lipopolysaccharide responsiveness is expressed in thyroid cells.

L. Fozzatti, J. Nicola, A. M. Masini-Repiso, 2009, Endocrinology.

Thyroid peroxidase gene expression is induced by lipopolysaccharide involving nuclear factor (NF)-κB p65 subunit phosphorylation.

J. Nicola, A. M. Masini-Repiso, M. L. Vélez, 2012, Endocrinology.

Nuclear Factor (NF)-κB-dependent Thyroid Hormone Receptor β1 Expression Controls Dendritic Cell Function via Akt Signaling*

G. Rabinovich, J. Ilarregui, J. Nicola, 2009, The Journal of Biological Chemistry.

S-Nitrosylation of NF-κB p65 Inhibits TSH-Induced Na(+)/I(-) Symporter Expression.

J. Bocco, J. Nicola, A. M. Masini-Repiso, 2015, Endocrinology.

The ERα membrane pool modulates the proliferation of pituitary tumours.

J. Valdez-Taubas, L. D. Sosa, A. D. De Paul, 2019, The Journal of endocrinology.

Transcription Factor CREB3L1 Regulates the Expression of the Sodium/Iodide Symporter (NIS) in Rat Thyroid Follicular Cells

C. Alvarez, J. Nicola, Mariano Martín, 2022, Cells.

The Na+/I- symporter mediates active iodide uptake in the intestine.

N. Carrasco, A. Reyna-Neyra, J. Nicola, 2009, American journal of physiology. Cell physiology.

Family Study Designs to Combat Heterogeneity and Identify Multi-Cancer Pleiotropies: The Power of the Utah Population Database

P. Bernard, H. Hanson, J. Doherty, 2020 .

Inefficient N2-Like Neutrophils Are Promoted by Androgens During Infection

G. Menezes, J. Nicola, C. Leimgruber, 2018, Front. Immunol..

Nitric oxide-repressed Forkhead factor FoxE1 expression is involved in the inhibition of TSH-induced thyroid peroxidase levels

J. Nicola, A. M. Masini-Repiso, Victoria Peyret, 2016, Molecular and Cellular Endocrinology.

Structural insights into the mechanism of the sodium/iodide symporter (NIS)

F. Sigworth, S. Ravera, N. Carrasco, 2022 .

The KCNQ1-KCNE2 K channel is required for adequate thyroid I (cid:2) uptake

G. Abbott, N. Carrasco, A. Reyna-Neyra, 2012 .

Targeted Next-Generation Sequencing of Congenital Hypothyroidism-Causative Genes Reveals Unexpected Thyroglobulin Gene Variants in Patients with Iodide Transport Defect

Cintia E. Citterio, F. Savagner, A. Chiesa, 2022, International journal of molecular sciences.

Silent but Not Harmless: A Synonymous SLC5A5 Gene Variant Leading to Dyshormonogenic Congenital Hypothyroidism

J. Nicola, A. M. Masini-Repiso, M. Miras, 2022, Frontiers in Endocrinology.

Clinical Relevance of Molecular Diagnosis in Patients with CongenitalHypothyroidism

J. Nicola, 2017 .

Dietary iodide controls its own absorption through post‐transcriptional regulation of the intestinal Na+/I− symporter

N. Carrasco, A. Reyna-Neyra, J. Nicola, 2012, The Journal of physiology.

MotSASi: Functional Short Linear Motifs (SLiMs) prediction based on genomic single nucleotide variants and structural data

Carlos P. Modenutti, M. Martí, C. Modenutti, 2021 .

Asn441 plays a key role in folding and function of the Na⁺/I^â•fi symporter (NIS)

L. Amzel, N. Carrasco, J. Nicola, 2013 .

Structural insights into the mechanism of the sodium/iodide symporter

F. Sigworth, S. Ravera, N. Carrasco, 2022, Nature.

Testosterone Rescues the De‐Differentiation of Smooth Muscle Cells Through Serum Response Factor/Myocardin

J. Miano, J. Nicola, C. Leimgruber, 2017, Journal of cellular physiology.

The Na+/I− Symporter (NIS) and Thyroid Hormone Biosynthesis

N. Carrasco, J. Nicola, 2014 .

Expression of Toll‐like receptor 4 in the prostate gland and its association with the severity of prostate cancer

V. Rivero, J. Nicola, A. M. Masini-Repiso, 2009, The Prostate.

Effects of 2-iodohexadecanal in the physiology of thyroid cells

C. Christophe-Hobertus, D. Christophe, M. Pisarev, 2016, Molecular and Cellular Endocrinology.

Potentiates Antipurine Antifolate Activity in the Presence of Hypoxanthine in Tumor Cells but not in Normal Tissues in Vitro 1

Newell, David, Calvert, 2005 .

An intramolecular ionic interaction linking defective sodium/iodide symporter transport to the plasma membrane and dyshormonogenic congenital hypothyroidism.

A. Chiesa, J. Nicola, A. M. Masini-Repiso, 2021, Thyroid : official journal of the American Thyroid Association.

Testosterone-loaded GM1 micelles targeted to the intracellular androgen receptor for the specific induction of genomic androgen signaling.

R. Alasino, D. Beltramo, L. D. Sosa, 2020, International journal of pharmaceutics.

Sodium iodide symporter-targeted gene therapy in glioblastoma

J. Nicola, C. LaRocca, 2023, Molecular therapy oncolytics.

Physiological sodium concentrations enhance the iodide affinity of the Na+/I− symporter

L. Amzel, N. Carrasco, J. Nicola, 2014, Nature Communications.

Functional Toll-like Receptor 4 Overexpression in Papillary Thyroid Cancer by MAPK/ERK–Induced ETS1 Transcriptional Activity

P. Santisteban, E. Kimura, C. S. Fuziwara, 2018, Molecular Cancer Research.

MCR-17-0433-AT 833..845

P. Santisteban, E. Kimura, C. S. Fuziwara, 2018 .

The PDZ protein SCRIB regulates sodium/iodide symporter (NIS) expression at the basolateral plasma membrane

S. Lindenthal, T. Pourcher, E. Darrouzet, 2021, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Endogenous thyrocyte-produced nitric oxide inhibits iodide uptake and thyroid-specific gene expression in FRTL-5 thyroid cells.

D. Macció, L. Fozzatti, G. A. Roth, 2007, The Journal of endocrinology.

The expansion of adult stem/progenitor cells and their marker expression fluctuations are linked with pituitary plastic adaptation during gestation and lactancy.

L. D. Sosa, J. P. Petiti, J. Nicola, 2016, American journal of physiology. Endocrinology and metabolism.

Iodide transport defect: functional characterization of a novel mutation in the Na+/I- symporter 5'-untranslated region in a patient with congenital hypothyroidism.

C. Serrano-Nascimento, J. Nicola, A. M. Masini-Repiso, 2011, The Journal of clinical endocrinology and metabolism.

The Response of Prostate Smooth Muscle Cells to Testosterone Is Determined by the Subcellular Distribution of the Androgen Receptor

J. Nicola, C. Leimgruber, A. Quintar, 2018, Endocrinology.

A Novel SLC5A5 Variant Reveals the Crucial Role of Kinesin Light Chain 2 in Thyroid Hormonogenesis.

Carlos P. Modenutti, N. Calcaterra, Marcelo Martí, 2021, The Journal of clinical endocrinology and metabolism.

Secreted Factors by Anaplastic Thyroid Cancer Cells Induce Tumor-Promoting M2-like Macrophage Polarization through a TIM3-Dependent Mechanism

Sheue-yann Cheng, L. Fozzatti, E. A. Acosta Rodríguez, 2021, Cancers.

NF-kappaB p65 subunit mediates lipopolysaccharide-induced Na(+)/I(-) symporter gene expression by involving functional interaction with the paired domain transcription factor Pax8.

J. Nicola, A. M. Masini-Repiso, I. Mascanfroni, 2010, Molecular endocrinology.

Impact of the mutational landscape of the sodium/iodide symporter in congenital hypothyroidism.

J. Nicola, Mariano Martín, 2021, Thyroid : official journal of the American Thyroid Association.

Structural insights into sodium/iodide symporter (NIS) substrate binding and specificity

F. Sigworth, L. Amzel, S. Ravera, 2022, bioRxiv.

Beyond non-integer Hill coefficients: A novel approach to analyzing binding data, applied to Na+-driven transporters

M. Quick, S. Ravera, N. Carrasco, 2015, The Journal of general physiology.

Excess iodide downregulates Na+/I− symporter gene transcription through activation of PI3K/Akt pathway

C. Serrano-Nascimento, Camilo Lellis-Santos, S. Bordin, 2016, Molecular and Cellular Endocrinology.

The acute inhibitory effect of iodide excess on sodium/iodide symporter expression and activity involves the PI3K/Akt signaling pathway.

C. Serrano-Nascimento, R. Nachbar, J. Nicola, 2014, Endocrinology.

Congenital iodide transport defect: recent advances and future perspectives

J. Nicola, Mariano Martín, 2016 .

Na+ coordination at the Na2 site of the Na+/I− symporter

Ignacia Echeverria, Yunlong Liu, N. Carrasco, 2016, Proceedings of the National Academy of Sciences.

The iodide-transport-defect-causing mutation R124H: a &dgr;-amino group at position 124 is critical for maturation and trafficking of the Na+/I− symporter

C. Ginter, N. Carrasco, V. Paroder, 2013, Journal of Cell Science.

Asn441 plays a key role in folding and function of the Na+/I– symporter (NIS)

N. Carrasco, J. Nicola, L. Amzel, 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

MotSASi: Functional short linear motifs (SLiMs) prediction based on genomic single nucleotide variants and structural data.

Carlos P. Modenutti, M. Martí, C. Modenutti, 2022, Biochimie.

Novel Sodium/Iodide Symporter Compound Heterozygous Pathogenic Variants Causing Dyshormonogenic Congenital Hypothyroidism.

A. Chiesa, J. Nicola, Mariano Martín, 2019, Thyroid : official journal of the American Thyroid Association.

Dissecting endocytic mechanisms reveals new molecular targets to enhance sodium iodide symporter activity with clinical relevance to radioiodide therapy

M. Campbell, M. Ringel, S. Jhiang, 2023, bioRxiv.

TIM3 Expression in Anaplastic-Thyroid-Cancer-Infiltrating Macrophages: An Emerging Immunotherapeutic Target

L. Fozzatti, M. C. Rodriguez-Galan, J. Nicola, 2022, Biology.

The KCNQ1‐KCNE2 K+ channel is required for adequate thyroid I− uptake

G. Abbott, N. Carrasco, A. Reyna-Neyra, 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The Na+/I- symporter mediates active iodide uptake in the intestine.

N. Carrasco, A. Reyna-Neyra, J. Nicola, 2009, American journal of physiology. Cell physiology.

Thyroid peroxidase gene expression is induced by lipopolysaccharide involving nuclear factor (NF)-κB p65 subunit phosphorylation.

J. Nicola, M. L. Vélez, C. Pellizas, 2012, Endocrinology.

Targeted Next-Generation Sequencing of Congenital Targeted Next-Generation Sequencing of Congenital Hypothyroidism-causative Genes Reveals Unexpected Hypothyroidism-causative Genes Reveals Unexpected Thyroglobulin Gene Variants in Patients with Iodide Transport Thyroglobulin Gene Variants in Patient

Cintia E. Citterio, J. Nicola, Mariano Martín, 2022 .

MOLECULAR MECHANISMS UNDERLYING SODIUM IODIDE SYMPORTER EXPRESSION AT THE PLASMA MEMBRANE IN THE THYROID FOLLICULAR CELL

J. Nicola, Gerardo Hernán Carro, 2023, Current Opinion in Endocrine and Metabolic Research.

Nitric oxide-repressed Forkhead factor FoxE1 expression is involved in the inhibition of TSH-induced thyroid peroxidase levels

J. Nicola, Victoria Peyret, A. M. Lucero, 2016, Molecular and Cellular Endocrinology.