Bruce M Bechle

Highly potent and selective NaV1.7 inhibitors for use as intravenous agents and chemical probes.

Brian E Marron, Neil A Castle, Rubben Torella, 2017, Bioorganic & medicinal chemistry letters.

Discovery of Clinical Candidate 4-[2-(5-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-1,3-thiazol-4-ylbenzenesulfonamide (PF-05089771): Design and Optimization of Diaryl Ether Aryl Sulfonamides as Selective Inhibitors of NaV1.7.

P. A. Bradley, Brian E Marron, Ian K Gurrell, 2017, Journal of medicinal chemistry.