Jean-Pierre Marquette

Automated harvesting and processing of protein crystals through laser photoablation

Peter Murphy, Gergely Papp, Florent Cipriani, 2016, Acta crystallographica. Section D, Structural biology.

A highly potent and selective Vps34 inhibitor alters vesicle trafficking and autophagy.

Jean-Pierre Marquette, Magali Mathieu, Thomas Bertrand, 2014, Nature chemical biology.

SAR and X-ray. A new approach combining fragment-based screening and rational drug design: application to the discovery of nanomolar inhibitors of Src SH2.

Jean-Pierre Marquette, E. Mandine, G. Lange, 2002, Journal of medicinal chemistry.

Selective Inhibition of Mutant Isocitrate Dehydrogenase 1 (IDH1) via Disruption of a Metal Binding Network by an Allosteric Small Molecule

Dietmar Hoffmann, Jean-Pierre Marquette, Magali Mathieu, 2014, The Journal of Biological Chemistry.

Discovery and optimization of pyrimidone indoline amide PI3Kβ inhibitors for the treatment of phosphatase and tensin homologue (PTEN)-deficient cancers.

Jean-Pierre Marquette, Magali Mathieu, Thomas Bertrand, 2014, Journal of medicinal chemistry.